SE9903831D0 - Formulation of substituted benzimidazoles - Google Patents
Formulation of substituted benzimidazolesInfo
- Publication number
- SE9903831D0 SE9903831D0 SE9903831A SE9903831A SE9903831D0 SE 9903831 D0 SE9903831 D0 SE 9903831D0 SE 9903831 A SE9903831 A SE 9903831A SE 9903831 A SE9903831 A SE 9903831A SE 9903831 D0 SE9903831 D0 SE 9903831D0
- Authority
- SE
- Sweden
- Prior art keywords
- sodium
- formulation
- potassium salt
- polyethylene glycol
- liquid formulations
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000001556 benzimidazoles Chemical class 0.000 title 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 4
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 3
- 229910052708 sodium Inorganic materials 0.000 abstract 3
- 239000011734 sodium Substances 0.000 abstract 3
- 229940121819 ATPase inhibitor Drugs 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- 239000000362 adenosine triphosphatase inhibitor Substances 0.000 abstract 2
- 239000012669 liquid formulation Substances 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (37)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9903831A SE9903831D0 (sv) | 1999-10-22 | 1999-10-22 | Formulation of substituted benzimidazoles |
| ARP000105283A AR029005A1 (es) | 1999-10-22 | 2000-10-06 | FORMULACION LíQUIDA ESTABLE SIN AGUA O CASI SIN AGUA DE BENCIMIDAZOLES SUSTITUIDOS, PROCESO PARA SU PREPARACIoN, USO DE ESTA FORMULACIoN, Y USO DE POLIETILENGLICOL Y UNA SAL DE SODIO O POTASIO DE UN INHIBIDOR DE H+, K+-ATP ASA |
| TW089121063A TWI236372B (en) | 1999-10-22 | 2000-10-09 | Formulation of substituted benzimidazoles |
| KR1020027005112A KR100785603B1 (ko) | 1999-10-22 | 2000-10-13 | 치환된 벤즈이미다졸의 제제 |
| HU0203121A HUP0203121A3 (en) | 1999-10-22 | 2000-10-13 | Pharmaceutical composition containing substituted benzimidazoles and its use |
| JP2001531388A JP2003512327A (ja) | 1999-10-22 | 2000-10-13 | 置換ベンズイミダゾール製剤 |
| NZ518155A NZ518155A (en) | 1999-10-22 | 2000-10-13 | Formulation of substituted benzimidazoles |
| HK03103347.1A HK1051142B (en) | 1999-10-22 | 2000-10-13 | Formulation of substituted benzimidazoles |
| RU2002110328/15A RU2286782C2 (ru) | 1999-10-22 | 2000-10-13 | Препарат замещенных бензимидазолов |
| UA2002043345A UA74347C2 (uk) | 1999-10-22 | 2000-10-13 | Безводна або майже безводна, стабільна рідка композиція |
| TR2002/01103T TR200201103T2 (tr) | 1999-10-22 | 2000-10-13 | İkame edilmiş benzimidazol formülasyonları |
| SI200030759T SI1274427T1 (sl) | 1999-10-22 | 2000-10-13 | Formulacija substituiranih benzimidazolov |
| AU11823/01A AU782866B2 (en) | 1999-10-22 | 2000-10-13 | Formulation of substituted benzimidazoles |
| MXPA02003900A MXPA02003900A (es) | 1999-10-22 | 2000-10-13 | Formulacion de benzimidazoles sustituidos. |
| AT00973295T ATE304851T1 (de) | 1999-10-22 | 2000-10-13 | Zusammensetzung die substituierte benzimidazole enthält |
| US09/701,714 US6730685B1 (en) | 1999-10-22 | 2000-10-13 | Formulation of substituted benzimidazoles |
| DE60022789T DE60022789T2 (de) | 1999-10-22 | 2000-10-13 | Zusammensetzung die substituierte benzimidazole enthält |
| IL14910700A IL149107A0 (en) | 1999-10-22 | 2000-10-13 | Formulation of substituted benzimidazoles |
| SK539-2002A SK286266B6 (sk) | 1999-10-22 | 2000-10-13 | Stabilný kvapalinový prípravok, spôsob jeho prípravy a jeho použitie |
| PL354926A PL199868B1 (pl) | 1999-10-22 | 2000-10-13 | Trwały ciekły preparat inhibitora H⁺ , K⁺-ATPazy, sposób jego wytwarzania, zastosowanie glikolu polietylenowego i soli sodowej lub potasowej inhibitora H⁺ , K⁺-ATPazy oraz zastosowanie tego preparatu |
| ES00973295T ES2246903T3 (es) | 1999-10-22 | 2000-10-13 | Formulacion de bencimidazoles sustituidos. |
| DK00973295T DK1274427T3 (da) | 1999-10-22 | 2000-10-13 | Formulering af substituerede benzimidazoler |
| PCT/SE2000/001992 WO2001028558A1 (en) | 1999-10-22 | 2000-10-13 | Formulation of substituted benzimidazoles |
| BR0014895-4A BR0014895A (pt) | 1999-10-22 | 2000-10-13 | Formulação lìquida estável, processo para a preparação da mesma, uso da mesma, uso de polietileno glicol e sal de sódio ou potássio de um inibidor h+, k+-atpase, e, método para tratar doenças gastrointestinais |
| EP00973295A EP1274427B1 (en) | 1999-10-22 | 2000-10-13 | Formulation of substituted benzimidazoles |
| CZ20021375A CZ20021375A3 (cs) | 1999-10-22 | 2000-10-13 | Prostředek na bázi substituovaného benzimidazolu |
| CA2425199A CA2425199C (en) | 1999-10-22 | 2000-10-13 | Formulation of substituted benzimidazoles |
| CNB008146373A CN1213751C (zh) | 1999-10-22 | 2000-10-13 | 取代苯并咪唑的制剂 |
| EEP200200204A EE05175B1 (et) | 1999-10-22 | 2000-10-13 | Asendatud bensimidasooli preparaat, meetod selle valmistamiseks ja selle kasutamine meditsiinis |
| CO00079671A CO5261533A1 (es) | 1999-10-22 | 2000-10-19 | Formulaciones parenterales liquidas estables libres de agua que comprenden sales de sodio o potasio de bencimidazoles sustituidos y polietilenglicol |
| MYPI20004932A MY131971A (en) | 1999-10-22 | 2000-10-19 | Formulation of substituted benzimidazoles |
| BG106602A BG65580B1 (bg) | 1999-10-22 | 2002-04-10 | Течен състав със заместени бензимидазоли |
| IL149107A IL149107A (en) | 1999-10-22 | 2002-04-11 | Stable liquid formulations of converted benzimidazoles, a process for their preparation and use in the preparation of a drug for the treatment of gastric and intestinal diseases |
| ZA200202905A ZA200202905B (en) | 1999-10-22 | 2002-04-12 | Formulation of substituted benzimidazoles. |
| IS6347A IS2196B (is) | 1999-10-22 | 2002-04-17 | Blanda útskiptra bensimídasóla |
| NO20021860A NO329545B1 (no) | 1999-10-22 | 2002-04-19 | Stabil flytende formulering, fremgangsmate for fremstilling derav, samt anvendelse derav i medisin |
| CY20051101567T CY1106055T1 (el) | 1999-10-22 | 2005-12-19 | Τυποποιηση των υποκατεστημενων βενζιμιδαζολων |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9903831A SE9903831D0 (sv) | 1999-10-22 | 1999-10-22 | Formulation of substituted benzimidazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9903831D0 true SE9903831D0 (sv) | 1999-10-22 |
Family
ID=20417464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9903831A SE9903831D0 (sv) | 1999-10-22 | 1999-10-22 | Formulation of substituted benzimidazoles |
Country Status (35)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001276721A1 (en) * | 2000-08-04 | 2002-02-18 | Takeda Chemical Industries Ltd. | Salts of benzimidazole compound and use thereof |
| WO2002015908A1 (en) * | 2000-08-18 | 2002-02-28 | Takeda Chemical Industries, Ltd. | Injections |
| MY137726A (en) * | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
| GB2376231A (en) * | 2001-06-06 | 2002-12-11 | Cipla Ltd | Benzimidazole-cyclodextrin inclusion complex |
| MXPA04002973A (es) | 2001-09-28 | 2005-06-20 | Johnson & Johnson | Formas de dosis de liberacion modificada. |
| FR2845915B1 (fr) * | 2002-10-21 | 2006-06-23 | Negma Gild | Utilisation du tenatoprazole pour le traitement du reflux gastro-oesophagien |
| FR2845916B1 (fr) * | 2002-10-21 | 2006-07-07 | Negma Gild | Composition pharmaceutique associant le tenatoprazole et un antagoniste des recepteurs h2 a l'histamine |
| FR2845917B1 (fr) * | 2002-10-21 | 2006-07-07 | Negma Gild | Composition pharmaceutique associant le tenatoprazole et un anti-inflammatoire |
| FR2848555B1 (fr) | 2002-12-16 | 2006-07-28 | Negma Gild | Enantiomere(-)du tenatoprazole et son application en therapeutique |
| CN100558726C (zh) * | 2003-02-24 | 2009-11-11 | 田边三菱制药株式会社 | 泰妥拉唑的对映体及其在治疗中的应用 |
| TWI372066B (en) * | 2003-10-01 | 2012-09-11 | Wyeth Corp | Pantoprazole multiparticulate formulations |
| US20060089376A1 (en) * | 2004-10-27 | 2006-04-27 | Joshi Ramesh A | Tenatoprazole salts and process of preparation thereof |
| AU2007248949B2 (en) * | 2006-05-09 | 2010-04-08 | Astrazeneca Ab | Parenteral formulation comprising proton pump inhibitor sterilized in its final container by ionizing radiation |
| CN100411613C (zh) * | 2006-12-08 | 2008-08-20 | 中国药科大学 | 一种奥美拉唑速释固体制剂及其制备方法 |
| JP6698651B2 (ja) | 2014-11-13 | 2020-05-27 | スリーエム イノベイティブ プロパティズ カンパニー | 試料中の細菌ａｔｐを検出するためのａｔｐ−ジホスホヒドロラーゼを含むキット |
| US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| WO2025078989A1 (en) * | 2023-10-11 | 2025-04-17 | Reena Patel | Stabilized pharmaceutical compositions |
| WO2025181379A1 (en) * | 2024-03-01 | 2025-09-04 | Etico Lifesciences Private Limited | Liquid, storage stable, directly injectable, pantoprazole formulations, their uses and manufacturing |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| IL75400A (en) | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
| JPS6150978A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| AU4640985A (en) | 1984-08-31 | 1986-03-06 | Nippon Chemiphar Co. Ltd. | Benzimidazole derivatives |
| DK399389A (da) | 1988-08-18 | 1990-02-19 | Takeda Chemical Industries Ltd | Injicerbare oploesninger |
| JP2536173B2 (ja) * | 1988-08-18 | 1996-09-18 | 武田薬品工業株式会社 | 注射剤 |
| KR930000861B1 (ko) * | 1990-02-27 | 1993-02-08 | 한미약품공업 주식회사 | 오메프라졸 직장투여 조성물 |
| SG52479A1 (en) | 1992-07-28 | 1998-09-28 | Astra Ab | Injection and injection kit containing omeprazole and its analogs |
| SE9301830D0 (sv) | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| SE9302396D0 (sv) * | 1993-07-09 | 1993-07-09 | Ab Astra | A novel compound form |
| TW359614B (en) | 1993-08-31 | 1999-06-01 | Takeda Chemical Industries Ltd | Composition containing benzimidazole compounds for rectal administration |
| US5726181A (en) | 1995-06-05 | 1998-03-10 | Bionumerik Pharmaceuticals, Inc. | Formulations and compositions of poorly water soluble camptothecin derivatives |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US5877205A (en) | 1996-06-28 | 1999-03-02 | Board Of Regents, The University Of Texas System | Parenteral paclitaxel in a stable non-toxic formulation |
| SE510643C2 (sv) | 1997-06-27 | 1999-06-14 | Astra Ab | Termodynamiskt stabil omeprazol natrium form B |
| US6287594B1 (en) * | 1998-01-20 | 2001-09-11 | Edward S. Wilson | Oral liquid compositions |
-
1999
- 1999-10-22 SE SE9903831A patent/SE9903831D0/xx unknown
-
2000
- 2000-10-06 AR ARP000105283A patent/AR029005A1/es unknown
- 2000-10-09 TW TW089121063A patent/TWI236372B/zh not_active IP Right Cessation
- 2000-10-13 SK SK539-2002A patent/SK286266B6/sk not_active IP Right Cessation
- 2000-10-13 DE DE60022789T patent/DE60022789T2/de not_active Expired - Lifetime
- 2000-10-13 ES ES00973295T patent/ES2246903T3/es not_active Expired - Lifetime
- 2000-10-13 NZ NZ518155A patent/NZ518155A/en unknown
- 2000-10-13 SI SI200030759T patent/SI1274427T1/sl unknown
- 2000-10-13 AU AU11823/01A patent/AU782866B2/en not_active Ceased
- 2000-10-13 PL PL354926A patent/PL199868B1/pl not_active IP Right Cessation
- 2000-10-13 CA CA2425199A patent/CA2425199C/en not_active Expired - Fee Related
- 2000-10-13 CZ CZ20021375A patent/CZ20021375A3/cs unknown
- 2000-10-13 CN CNB008146373A patent/CN1213751C/zh not_active Expired - Fee Related
- 2000-10-13 MX MXPA02003900A patent/MXPA02003900A/es active IP Right Grant
- 2000-10-13 US US09/701,714 patent/US6730685B1/en not_active Expired - Fee Related
- 2000-10-13 BR BR0014895-4A patent/BR0014895A/pt not_active IP Right Cessation
- 2000-10-13 AT AT00973295T patent/ATE304851T1/de active
- 2000-10-13 DK DK00973295T patent/DK1274427T3/da active
- 2000-10-13 EP EP00973295A patent/EP1274427B1/en not_active Expired - Lifetime
- 2000-10-13 UA UA2002043345A patent/UA74347C2/uk unknown
- 2000-10-13 IL IL14910700A patent/IL149107A0/xx active IP Right Grant
- 2000-10-13 TR TR2002/01103T patent/TR200201103T2/xx unknown
- 2000-10-13 EE EEP200200204A patent/EE05175B1/xx not_active IP Right Cessation
- 2000-10-13 JP JP2001531388A patent/JP2003512327A/ja active Pending
- 2000-10-13 HU HU0203121A patent/HUP0203121A3/hu unknown
- 2000-10-13 RU RU2002110328/15A patent/RU2286782C2/ru not_active IP Right Cessation
- 2000-10-13 KR KR1020027005112A patent/KR100785603B1/ko not_active Expired - Fee Related
- 2000-10-13 WO PCT/SE2000/001992 patent/WO2001028558A1/en not_active Ceased
- 2000-10-19 CO CO00079671A patent/CO5261533A1/es active IP Right Grant
- 2000-10-19 MY MYPI20004932A patent/MY131971A/en unknown
-
2002
- 2002-04-10 BG BG106602A patent/BG65580B1/bg unknown
- 2002-04-11 IL IL149107A patent/IL149107A/en not_active IP Right Cessation
- 2002-04-12 ZA ZA200202905A patent/ZA200202905B/en unknown
- 2002-04-17 IS IS6347A patent/IS2196B/is unknown
- 2002-04-19 NO NO20021860A patent/NO329545B1/no not_active IP Right Cessation
-
2005
- 2005-12-19 CY CY20051101567T patent/CY1106055T1/el unknown
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| DE60031699D1 (de) | Hydroxyacetamidobenzolsulfonamidderivate |