AU782866B2 - Formulation of substituted benzimidazoles - Google Patents

Formulation of substituted benzimidazoles Download PDF

Info

Publication number
AU782866B2
AU782866B2 AU11823/01A AU1182301A AU782866B2 AU 782866 B2 AU782866 B2 AU 782866B2 AU 11823/01 A AU11823/01 A AU 11823/01A AU 1182301 A AU1182301 A AU 1182301A AU 782866 B2 AU782866 B2 AU 782866B2
Authority
AU
Australia
Prior art keywords
sodium
liquid formulation
stable liquid
potassium salt
polyethylene glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU11823/01A
Other languages
English (en)
Other versions
AU1182301A (en
Inventor
Mikael Brulls
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU1182301A publication Critical patent/AU1182301A/en
Application granted granted Critical
Publication of AU782866B2 publication Critical patent/AU782866B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU11823/01A 1999-10-22 2000-10-13 Formulation of substituted benzimidazoles Ceased AU782866B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9903831A SE9903831D0 (sv) 1999-10-22 1999-10-22 Formulation of substituted benzimidazoles
SE9903831 1999-10-22
PCT/SE2000/001992 WO2001028558A1 (en) 1999-10-22 2000-10-13 Formulation of substituted benzimidazoles

Publications (2)

Publication Number Publication Date
AU1182301A AU1182301A (en) 2001-04-30
AU782866B2 true AU782866B2 (en) 2005-09-01

Family

ID=20417464

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11823/01A Ceased AU782866B2 (en) 1999-10-22 2000-10-13 Formulation of substituted benzimidazoles

Country Status (35)

Country Link
US (1) US6730685B1 (enExample)
EP (1) EP1274427B1 (enExample)
JP (1) JP2003512327A (enExample)
KR (1) KR100785603B1 (enExample)
CN (1) CN1213751C (enExample)
AR (1) AR029005A1 (enExample)
AT (1) ATE304851T1 (enExample)
AU (1) AU782866B2 (enExample)
BG (1) BG65580B1 (enExample)
BR (1) BR0014895A (enExample)
CA (1) CA2425199C (enExample)
CO (1) CO5261533A1 (enExample)
CY (1) CY1106055T1 (enExample)
CZ (1) CZ20021375A3 (enExample)
DE (1) DE60022789T2 (enExample)
DK (1) DK1274427T3 (enExample)
EE (1) EE05175B1 (enExample)
ES (1) ES2246903T3 (enExample)
HU (1) HUP0203121A3 (enExample)
IL (2) IL149107A0 (enExample)
IS (1) IS2196B (enExample)
MX (1) MXPA02003900A (enExample)
MY (1) MY131971A (enExample)
NO (1) NO329545B1 (enExample)
NZ (1) NZ518155A (enExample)
PL (1) PL199868B1 (enExample)
RU (1) RU2286782C2 (enExample)
SE (1) SE9903831D0 (enExample)
SI (1) SI1274427T1 (enExample)
SK (1) SK286266B6 (enExample)
TR (1) TR200201103T2 (enExample)
TW (1) TWI236372B (enExample)
UA (1) UA74347C2 (enExample)
WO (1) WO2001028558A1 (enExample)
ZA (1) ZA200202905B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002012225A1 (en) * 2000-08-04 2002-02-14 Takeda Chemical Industries, Ltd. Salts of benzimidazole compound and use thereof
EP1310252A4 (en) * 2000-08-18 2009-06-10 Takeda Pharmaceutical INJECTIONS
MY137726A (en) * 2000-11-22 2009-03-31 Nycomed Gmbh Freeze-dried pantoprazole preparation and pantoprazole injection
GB2376231A (en) * 2001-06-06 2002-12-11 Cipla Ltd Benzimidazole-cyclodextrin inclusion complex
FR2845915B1 (fr) * 2002-10-21 2006-06-23 Negma Gild Utilisation du tenatoprazole pour le traitement du reflux gastro-oesophagien
FR2845916B1 (fr) * 2002-10-21 2006-07-07 Negma Gild Composition pharmaceutique associant le tenatoprazole et un antagoniste des recepteurs h2 a l'histamine
FR2845917B1 (fr) * 2002-10-21 2006-07-07 Negma Gild Composition pharmaceutique associant le tenatoprazole et un anti-inflammatoire
FR2848555B1 (fr) * 2002-12-16 2006-07-28 Negma Gild Enantiomere(-)du tenatoprazole et son application en therapeutique
KR20050123096A (ko) * 2003-02-24 2005-12-29 미쯔비시 웰 파마 가부시키가이샤 테나토프라졸의 거울상 이성질체 및 치료를 위한 그 용도
TWI372066B (en) * 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
US20060089376A1 (en) * 2004-10-27 2006-04-27 Joshi Ramesh A Tenatoprazole salts and process of preparation thereof
BRPI0711048A2 (pt) * 2006-05-09 2011-08-23 Astrazeneca Ab formulações parenteral esterilizada e sólida estáveis, solução para administração parenteral, processos para a preparação de uma formulação e para a fabricação de um produto, método para prevenir ou tratar doenças gastrintestinais, uso de uma formulação sólida estável
CN100411613C (zh) * 2006-12-08 2008-08-20 中国药科大学 一种奥美拉唑速释固体制剂及其制备方法
WO2016077185A1 (en) 2014-11-13 2016-05-19 3M Innovative Properties Company Kit comprising atp-diphosphohydrolase for detecting bacterial atp in a sample
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2025078989A1 (en) * 2023-10-11 2025-04-17 Reena Patel Stabilized pharmaceutical compositions
WO2025181379A1 (en) * 2024-03-01 2025-09-04 Etico Lifesciences Private Limited Liquid, storage stable, directly injectable, pantoprazole formulations, their uses and manufacturing

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
IL75400A (en) 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU4640985A (en) 1984-08-31 1986-03-06 Nippon Chemiphar Co. Ltd. Benzimidazole derivatives
DK399389A (da) * 1988-08-18 1990-02-19 Takeda Chemical Industries Ltd Injicerbare oploesninger
JP2536173B2 (ja) * 1988-08-18 1996-09-18 武田薬品工業株式会社 注射剤
KR930000861B1 (ko) 1990-02-27 1993-02-08 한미약품공업 주식회사 오메프라졸 직장투여 조성물
ATE144421T1 (de) 1992-07-28 1996-11-15 Astra Ab Injizierbares arzneimittel und satz, die omoprazol oder verwandte verbindungenenthalten
SE9301830D0 (sv) 1993-05-28 1993-05-28 Ab Astra New compounds
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
TW359614B (en) 1993-08-31 1999-06-01 Takeda Chemical Industries Ltd Composition containing benzimidazole compounds for rectal administration
US5726181A (en) 1995-06-05 1998-03-10 Bionumerik Pharmaceuticals, Inc. Formulations and compositions of poorly water soluble camptothecin derivatives
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US5877205A (en) 1996-06-28 1999-03-02 Board Of Regents, The University Of Texas System Parenteral paclitaxel in a stable non-toxic formulation
SE510643C2 (sv) 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
US6287594B1 (en) * 1998-01-20 2001-09-11 Edward S. Wilson Oral liquid compositions

Also Published As

Publication number Publication date
PL199868B1 (pl) 2008-11-28
HUP0203121A3 (en) 2004-01-28
IS6347A (is) 2002-04-17
DE60022789D1 (de) 2006-02-02
DE60022789T2 (de) 2006-06-22
NO20021860D0 (no) 2002-04-19
TWI236372B (en) 2005-07-21
HUP0203121A2 (hu) 2003-01-28
JP2003512327A (ja) 2003-04-02
BG65580B1 (bg) 2009-01-30
CO5261533A1 (es) 2003-03-31
WO2001028558A1 (en) 2001-04-26
SK5392002A3 (en) 2002-10-08
CN1213751C (zh) 2005-08-10
KR20020059637A (ko) 2002-07-13
EE05175B1 (et) 2009-06-15
ZA200202905B (en) 2003-07-14
CA2425199C (en) 2010-12-07
KR100785603B1 (ko) 2007-12-14
CZ20021375A3 (cs) 2002-09-11
NZ518155A (en) 2004-07-30
RU2286782C2 (ru) 2006-11-10
BG106602A (en) 2002-12-29
CY1106055T1 (el) 2011-04-06
ES2246903T3 (es) 2006-03-01
MY131971A (en) 2007-09-28
AU1182301A (en) 2001-04-30
IL149107A (en) 2008-04-13
IS2196B (is) 2007-01-15
BR0014895A (pt) 2002-06-18
DK1274427T3 (da) 2005-12-27
SK286266B6 (sk) 2008-06-06
HK1051142A1 (en) 2003-07-25
EE200200204A (et) 2003-04-15
ATE304851T1 (de) 2005-10-15
NO20021860L (no) 2002-05-21
IL149107A0 (en) 2002-11-10
PL354926A1 (en) 2004-03-22
EP1274427B1 (en) 2005-09-21
MXPA02003900A (es) 2002-09-30
NO329545B1 (no) 2010-11-08
AR029005A1 (es) 2003-06-04
US6730685B1 (en) 2004-05-04
TR200201103T2 (tr) 2002-08-21
UA74347C2 (uk) 2005-12-15
CN1382048A (zh) 2002-11-27
SE9903831D0 (sv) 1999-10-22
SI1274427T1 (sl) 2006-02-28
CA2425199A1 (en) 2001-04-26
EP1274427A1 (en) 2003-01-15

Similar Documents

Publication Publication Date Title
AU782866B2 (en) Formulation of substituted benzimidazoles
RU2126252C1 (ru) Препарат для инъекций и набор для инъекций, содержащие омепразол и его аналоги
IL304986A (en) Compositions and methods for inhibition of ras
SK6062003A3 (en) Freeze-dried pantoprazole preparation and pantoprazole injection
JPWO2006134877A1 (ja) 注射剤
AU2007248949B2 (en) Parenteral formulation comprising proton pump inhibitor sterilized in its final container by ionizing radiation
RU2002107421A (ru) Алкоксизамещенные бензимидазольные соединения, содержащие их фармацевтические препараты и способы их применения
HK1051142B (en) Formulation of substituted benzimidazoles
SK282353B6 (sk) Farmaceutický prostriedok na intravenózne podanie

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase
TH Corrigenda

Free format text: IN VOL 15, NO 33, PAGE(S) 6983-6987 UNDER THE HEADING APPLICATIONS LAPSED, REFUSED OR WITHDRAWN PLEASE DELETE ALL REFERENCE TO APPLICATION NO. 11823/01

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20020326