HUP9801924A2 - Nátrium/hidrogén-csere inhibitorokat és szív- és keringési zavarok kezelésére alkalmas hatóanyagokat tartalmazó gyógyszerkészítmény - Google Patents

Nátrium/hidrogén-csere inhibitorokat és szív- és keringési zavarok kezelésére alkalmas hatóanyagokat tartalmazó gyógyszerkészítmény

Info

Publication number
HUP9801924A2
HUP9801924A2 HU9801924A HUP9801924A HUP9801924A2 HU P9801924 A2 HUP9801924 A2 HU P9801924A2 HU 9801924 A HU9801924 A HU 9801924A HU P9801924 A HUP9801924 A HU P9801924A HU P9801924 A2 HUP9801924 A2 HU P9801924A2
Authority
HU
Hungary
Prior art keywords
inhibitors
hydrogen
containing sodium
exchange
pharmaceutical composition
Prior art date
Application number
HU9801924A
Other languages
English (en)
Inventor
Udo Albus
Wolfgang Scholz
Original Assignee
Hoechst Marion Roussel Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Deutschland Gmbh. filed Critical Hoechst Marion Roussel Deutschland Gmbh.
Publication of HU9801924D0 publication Critical patent/HU9801924D0/hu
Publication of HUP9801924A2 publication Critical patent/HUP9801924A2/hu
Publication of HUP9801924A3 publication Critical patent/HUP9801924A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

A találmány tárgya nátriűm/hidrőgén-csere inhibitőrőkat és szív- éskeringési betegségek kezelésére alkalmas hatóanyagőt tartalmazókőmbinációs gyógyszerkészítmény. A találmány értelmébennátriűm/hidrőgén-csere inhibitőrként előnyösen alkalamazhatókkülönböző benzőil-gűanidin-származékők. ŕ
HU9801924A 1997-08-27 1998-08-26 Combination containing sodium/hydrogen exchange inhibitors HUP9801924A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19737224A DE19737224A1 (de) 1997-08-27 1997-08-27 Pharmazeutisches Kombinationspräparat aus einem Inhibitor des Natrium-Wasserstoff-Austauschers und einem Arzneimittel zur Behandlung von Herz-Kreislauferkrankungen

Publications (3)

Publication Number Publication Date
HU9801924D0 HU9801924D0 (en) 1998-10-28
HUP9801924A2 true HUP9801924A2 (hu) 2000-02-28
HUP9801924A3 HUP9801924A3 (en) 2004-11-29

Family

ID=7840257

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801924A HUP9801924A3 (en) 1997-08-27 1998-08-26 Combination containing sodium/hydrogen exchange inhibitors

Country Status (23)

Country Link
US (1) US6348476B1 (hu)
EP (1) EP0937464B1 (hu)
JP (1) JP4436940B2 (hu)
KR (1) KR19990023904A (hu)
CN (1) CN1172665C (hu)
AR (1) AR017513A1 (hu)
AU (1) AU738598B2 (hu)
BR (1) BR9803233A (hu)
CA (1) CA2245776A1 (hu)
CZ (1) CZ270998A3 (hu)
DE (1) DE19737224A1 (hu)
HK (1) HK1018211A1 (hu)
HR (1) HRP980464A2 (hu)
HU (1) HUP9801924A3 (hu)
IL (1) IL125913A0 (hu)
NO (1) NO320264B1 (hu)
NZ (1) NZ331533A (hu)
PL (1) PL195566B1 (hu)
RU (1) RU2227751C2 (hu)
SK (1) SK116798A3 (hu)
TR (1) TR199801661A2 (hu)
TW (1) TW589175B (hu)
ZA (1) ZA987723B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19945302A1 (de) * 1999-09-22 2001-03-29 Merck Patent Gmbh Biphenylderivate als NHE-3-Inhibitoren
US6423705B1 (en) 2001-01-25 2002-07-23 Pfizer Inc. Combination therapy
IL147696A0 (en) * 2001-01-25 2002-08-14 Pfizer Prod Inc Combination therapy
US6844361B2 (en) 2002-02-04 2005-01-18 Aventis Pharma Deutschland Gmbh Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor
BR0307443A (pt) * 2002-02-04 2005-01-04 Aventis Pharma Gmbh Preparado de combinação do inibidor da troca sódio-hidrogênio cariporide com inibidores ace para o impedimento da insuficiência cardìaca e de outras disfunções de órgão condicionadas pela idade, doenças condicionadas pela idade e para o prolongamento da vida
US7375138B2 (en) * 2002-05-18 2008-05-20 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
FR2840302B1 (fr) * 2002-06-03 2004-07-16 Aventis Pharma Sa Derives d'isoindolones, procede de preparation et intermediaire de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
US6878748B2 (en) 2002-06-13 2005-04-12 Aventis Pharma Deutschland Gmbh Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them
RU2374224C2 (ru) * 2003-05-06 2009-11-27 Мерк Патент Гмбх Способ кристаллизации солей гуанидиния
US7534894B2 (en) 2003-09-25 2009-05-19 Wyeth Biphenyloxy-acids
US7531569B2 (en) * 2003-12-02 2009-05-12 Sanofi-Aventis Deutschland Gmbh Process for preparing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives
DE10356717A1 (de) * 2003-12-02 2005-07-07 Aventis Pharma Deutschland Gmbh Verfahren zur Herstellung von (3-Oxo-2,3-dihydro-1H-isoindol-1-yl)-acetylguanidin-Derivaten
CN101098679A (zh) * 2004-11-05 2008-01-02 国王医药研究与发展有限公司 稳定的雷米普利组合物及其制备方法
US10517839B2 (en) 2008-06-09 2019-12-31 Cornell University Mast cell inhibition in diseases of the retina and vitreous
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
EP3960165A1 (en) * 2020-08-25 2022-03-02 Fondation EspeRare Nhe-1 inhibitors for the treatment of coronavirus infections

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59307360D1 (de) 1992-02-15 1997-10-23 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0589336B1 (de) * 1992-09-22 1997-01-08 Hoechst Aktiengesellschaft Benzoylguanidine, Verfahren zu ihrer Herstellung, sowie ihre Verwendung als Antiarrhythmika
DE4328869A1 (de) 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4421536A1 (de) 1994-06-20 1995-12-21 Hoechst Ag Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4422685A1 (de) 1994-06-29 1996-01-04 Hoechst Ag Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4432106A1 (de) 1994-09-09 1996-03-14 Hoechst Ag Mit Heterocyclen-N-Oxid-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum, sie enthaltendes Medikament sowie Zwischenprodukte zu ihrer Herstellung
DE19741635A1 (de) * 1997-09-22 1999-03-25 Hoechst Marion Roussel De Gmbh Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament

Also Published As

Publication number Publication date
AR017513A1 (es) 2001-09-12
CA2245776A1 (en) 1999-02-27
EP0937464A3 (de) 2003-09-24
JP4436940B2 (ja) 2010-03-24
SK116798A3 (en) 1999-03-12
EP0937464A2 (de) 1999-08-25
PL328251A1 (en) 1999-03-01
NO983926D0 (no) 1998-08-26
PL195566B1 (pl) 2007-10-31
AU8190898A (en) 1999-03-11
BR9803233A (pt) 2000-05-02
EP0937464B1 (de) 2012-07-11
HUP9801924A3 (en) 2004-11-29
CZ270998A3 (cs) 1999-03-17
DE19737224A1 (de) 1999-03-18
CN1172665C (zh) 2004-10-27
AU738598B2 (en) 2001-09-20
TW589175B (en) 2004-06-01
NO320264B1 (no) 2005-11-14
NZ331533A (en) 2000-04-28
NO983926L (no) 1999-03-01
US6348476B1 (en) 2002-02-19
IL125913A0 (en) 1999-04-11
CN1209316A (zh) 1999-03-03
HU9801924D0 (en) 1998-10-28
HK1018211A1 (en) 1999-12-17
JPH11139990A (ja) 1999-05-25
ZA987723B (en) 1999-03-01
RU2227751C2 (ru) 2004-04-27
KR19990023904A (ko) 1999-03-25
HRP980464A2 (en) 1999-06-30
TR199801661A2 (xx) 1999-03-22

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