SE9604786D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE9604786D0
SE9604786D0 SE9604786A SE9604786A SE9604786D0 SE 9604786 D0 SE9604786 D0 SE 9604786D0 SE 9604786 A SE9604786 A SE 9604786A SE 9604786 A SE9604786 A SE 9604786A SE 9604786 D0 SE9604786 D0 SE 9604786D0
Authority
SE
Sweden
Prior art keywords
new compounds
compounds
pain
chem
therapy
Prior art date
Application number
SE9604786A
Other languages
English (en)
Swedish (sv)
Inventor
Edward Roberts
Benjamin Pelcman
Original Assignee
Astra Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Inc filed Critical Astra Pharma Inc
Priority to SE9604786A priority Critical patent/SE9604786D0/xx
Publication of SE9604786D0 publication Critical patent/SE9604786D0/xx
Priority to UA99074131A priority patent/UA54481C2/uk
Priority to IDW990536A priority patent/ID21662A/id
Priority to JP52867098A priority patent/JP2001507021A/ja
Priority to CNB971808376A priority patent/CN1154635C/zh
Priority to EP97950539A priority patent/EP0946510B1/en
Priority to DE69729115T priority patent/DE69729115T2/de
Priority to CNA2004100324204A priority patent/CN1539824A/zh
Priority to ES97950539T priority patent/ES2219783T3/es
Priority to AT97950539T priority patent/ATE266638T1/de
Priority to IL13053697A priority patent/IL130536A0/xx
Priority to AU53513/98A priority patent/AU738002B2/en
Priority to US09/029,468 priority patent/US6153626A/en
Priority to PT97950539T priority patent/PT946510E/pt
Priority to CZ992200A priority patent/CZ220099A3/cs
Priority to PCT/SE1997/002051 priority patent/WO1998028270A1/en
Priority to SK763-99A priority patent/SK283300B6/sk
Priority to TR1999/01411T priority patent/TR199901411T2/xx
Priority to ZA9711049A priority patent/ZA9711049B/xx
Priority to EP04002901A priority patent/EP1428821A1/en
Priority to KR1019997005586A priority patent/KR20000069600A/ko
Priority to RU99115746/04A priority patent/RU2193030C2/ru
Priority to HU0000613A priority patent/HUP0000613A3/hu
Priority to EEP199900261A priority patent/EE03966B1/xx
Priority to HK00103168.0A priority patent/HK1023996B/xx
Priority to PL97334370A priority patent/PL188945B1/pl
Priority to DK97950539T priority patent/DK0946510T3/da
Priority to BR9713785-5A priority patent/BR9713785A/pt
Priority to SI9730659T priority patent/SI0946510T1/xx
Priority to HK00102011.1A priority patent/HK1022910B/en
Priority to CA002274117A priority patent/CA2274117A1/en
Priority to NZ336028A priority patent/NZ336028A/en
Priority to ARP970106076A priority patent/AR010378A1/es
Priority to MYPI97006174A priority patent/MY132705A/en
Priority to IS5078A priority patent/IS5078A/is
Priority to NO19993023A priority patent/NO313632B1/no
Priority to US09/645,565 priority patent/US6399635B1/en
Priority to US10/121,683 priority patent/US6710179B2/en
Priority to US10/628,309 priority patent/US6974825B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
SE9604786A 1996-12-20 1996-12-20 New compounds SE9604786D0 (sv)

Priority Applications (39)

Application Number Priority Date Filing Date Title
SE9604786A SE9604786D0 (sv) 1996-12-20 1996-12-20 New compounds
UA99074131A UA54481C2 (uk) 1996-12-20 1997-09-12 Сполуки з аналгезивною дією, спосіб їх отримання, фармакологічна композиція та діагностичний агент на їхній основі
NZ336028A NZ336028A (en) 1996-12-20 1997-12-09 Substituted 4-amino-piperidine and pyrrolidine derivatives having an analgesic effect
ZA9711049A ZA9711049B (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect.
KR1019997005586A KR20000069600A (ko) 1996-12-20 1997-12-09 진통 효과가 있는 신규 화합물
CNB971808376A CN1154635C (zh) 1996-12-20 1997-12-09 具有止痛作用的新化合物
EP97950539A EP0946510B1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
DE69729115T DE69729115T2 (de) 1996-12-20 1997-12-09 Verbindungen mit analgetischer wirkung
HU0000613A HUP0000613A3 (en) 1996-12-20 1997-12-09 Piperidine derivatives with analgesic effect process for producing them and pharmaceutical compositions containing them
ES97950539T ES2219783T3 (es) 1996-12-20 1997-12-09 Nuevos compuestos con efecto analgesico.
AT97950539T ATE266638T1 (de) 1996-12-20 1997-12-09 Verbindungen mit analgetischer wirkung
IL13053697A IL130536A0 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
AU53513/98A AU738002B2 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
US09/029,468 US6153626A (en) 1996-12-20 1997-12-09 Compounds with analgesic effect
PT97950539T PT946510E (pt) 1996-12-20 1997-12-09 Novos compostos com efeito analgesico
CZ992200A CZ220099A3 (cs) 1996-12-20 1997-12-09 Nové sloučeniny s analgetickým účinkem
PCT/SE1997/002051 WO1998028270A1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
SK763-99A SK283300B6 (sk) 1996-12-20 1997-12-09 Piperidínové zlúčeniny s analgetickým účinkom, spôsob ich prípravy, medziprodukty na ich prípravu, ich použitie, diagnostické činidlo a farmaceutické kompozície s ich obsahom
TR1999/01411T TR199901411T2 (xx) 1996-12-20 1997-12-09 Analjezik etkili yeni bile�imler.
IDW990536A ID21662A (id) 1996-12-20 1997-12-09 Senyawa-senyawa baru dengan efek analgesik
EP04002901A EP1428821A1 (en) 1996-12-20 1997-12-09 Piperidin-4-yl amines with analgesic effect
RU99115746/04A RU2193030C2 (ru) 1996-12-20 1997-12-09 Азотсодержащие гетероциклические соединения, способ их получения, фармацевтическая композиция на их основе и промежуточные вещества
JP52867098A JP2001507021A (ja) 1996-12-20 1997-12-09 鎮痛作用を有する新規な化合物
CNA2004100324204A CN1539824A (zh) 1996-12-20 1997-12-09 具有止痛作用的新化合物
EEP199900261A EE03966B1 (et) 1996-12-20 1997-12-09 Valuvaigistava toimega ühendid ja nende valmistamise meetod
HK00103168.0A HK1023996B (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
PL97334370A PL188945B1 (pl) 1996-12-20 1997-12-09 Heterocykliczne związki z atomem azotu, ich zastosowanie, środek diagnostyczny, środek farmaceutyczny, sposób wytwarzania heterocyklicznych związków z atomem azotu oraz nowe związki pośrednie
DK97950539T DK0946510T3 (da) 1996-12-20 1997-12-09 Hidtil ukendte forbindelser med analgetisk virkning
BR9713785-5A BR9713785A (pt) 1996-12-20 1997-12-09 Composto, uso do mesmo, agente de diagnóstico, composição farmacêutica, e, processos para a preparação de um composto e para o tratamento da dor, de distúrbios gastrointestinais e de lesões na coluna vertebral.
SI9730659T SI0946510T1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
HK00102011.1A HK1022910B (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
CA002274117A CA2274117A1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect
MYPI97006174A MY132705A (en) 1996-12-20 1997-12-19 Novel compounds with analgesic effect
ARP970106076A AR010378A1 (es) 1996-12-20 1997-12-19 Novedosos compuestos con efecto analgesico, uso de los mismos para la preparacion de un medicamento y como agente de diagnostico, composicion farmaceutica, proceso para la preparacion de dichos compuestos y compuestos intermediarios
IS5078A IS5078A (is) 1996-12-20 1999-06-11 Ný efnasambönd með verkjadeyfandi áhrif
NO19993023A NO313632B1 (no) 1996-12-20 1999-06-18 Nye forbindelser med analgetisk effekt, farmasöytisk preparat inneholdende slike forbindelser, deres anvendelse, fremgangsmåtefor deres fremstilling og mellomprodukter
US09/645,565 US6399635B1 (en) 1996-12-20 2000-08-25 Compounds with analgesic effect
US10/121,683 US6710179B2 (en) 1996-12-20 2002-04-15 Compounds with analgesic effect
US10/628,309 US6974825B1 (en) 1996-12-20 2003-07-29 Compounds with analgesic effect

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9604786A SE9604786D0 (sv) 1996-12-20 1996-12-20 New compounds

Publications (1)

Publication Number Publication Date
SE9604786D0 true SE9604786D0 (sv) 1996-12-20

Family

ID=20405139

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9604786A SE9604786D0 (sv) 1996-12-20 1996-12-20 New compounds

Country Status (31)

Country Link
US (3) US6153626A (enExample)
EP (2) EP0946510B1 (enExample)
JP (1) JP2001507021A (enExample)
KR (1) KR20000069600A (enExample)
CN (2) CN1154635C (enExample)
AR (1) AR010378A1 (enExample)
AT (1) ATE266638T1 (enExample)
AU (1) AU738002B2 (enExample)
BR (1) BR9713785A (enExample)
CA (1) CA2274117A1 (enExample)
CZ (1) CZ220099A3 (enExample)
DE (1) DE69729115T2 (enExample)
DK (1) DK0946510T3 (enExample)
EE (1) EE03966B1 (enExample)
ES (1) ES2219783T3 (enExample)
HU (1) HUP0000613A3 (enExample)
ID (1) ID21662A (enExample)
IL (1) IL130536A0 (enExample)
IS (1) IS5078A (enExample)
MY (1) MY132705A (enExample)
NO (1) NO313632B1 (enExample)
NZ (1) NZ336028A (enExample)
PL (1) PL188945B1 (enExample)
PT (1) PT946510E (enExample)
RU (1) RU2193030C2 (enExample)
SE (1) SE9604786D0 (enExample)
SK (1) SK283300B6 (enExample)
TR (1) TR199901411T2 (enExample)
UA (1) UA54481C2 (enExample)
WO (1) WO1998028270A1 (enExample)
ZA (1) ZA9711049B (enExample)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
AU2003220725B2 (en) * 1997-12-24 2006-06-01 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor
WO1999033806A1 (en) * 1997-12-24 1999-07-08 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor
US6900228B1 (en) 1998-03-10 2005-05-31 Research Triangle Institute Opiate compounds, methods of making and methods of use
AU756983B2 (en) * 1998-03-10 2003-01-30 Research Triangle Institute Novel opiate compounds, methods of making and methods of use
US6436959B1 (en) 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904674D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
EP1242421A1 (en) 1999-12-22 2002-09-25 Ortho-McNeil Pharmaceutical, Inc. 4-[aryl(8-azabicyclo[3.2.1] octan-3-yl)] aminobenzoic acid derivatives
CA2400640A1 (en) * 2000-02-18 2001-08-23 Meiji Seika Kaisha, Ltd. Phenoxyalkylamine derivatives useful as opioid .delta. receptor ligands
IL151550A0 (en) 2000-03-03 2003-04-10 Ortho Mcneil Pharm Inc 3-(diarylmethylene)-8-azabicyclo [3.2.1] octane derivatives
CA2404280A1 (en) 2000-03-24 2002-09-23 Meiji Seika Kaisha, Ltd. Diphenylalkylamine derivatives useful as opioid .delta. receptor agonists
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
AU2002234010A1 (en) * 2000-12-14 2002-06-24 Ortho-Mcneil Pharmaceutical, Inc. Benzamidine derivatives
AU2002222879B2 (en) * 2000-12-15 2006-02-02 Astrazeneca Ab New process for the preparation diaryl-4-amino-piperidinyl compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
US7229994B2 (en) 2001-05-18 2007-06-12 Astrazeneca Ab 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders
SE0101770D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
EA006507B1 (ru) 2001-10-15 2005-12-29 Янссен Фармацевтика Н.В. Новые замещенные 4-фенил-4-[1h-имидазол-2-ил] пиперидиновые производные и их применение в качестве селективных непептидных агонистов дельта-опиоидов
US7501417B2 (en) * 2002-03-13 2009-03-10 Janssen Pharmaceutica, N.V. Aminocarbonyl-derivatives as novel inhibitors of histone deacetylase
EP2399903A1 (en) 2002-05-24 2011-12-28 Millennium Pharmaceuticals, Inc. Ccr9 inhibitors and methods of use thereof
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
US7227035B2 (en) 2002-11-18 2007-06-05 Chemocentryx Bis-aryl sulfonamides
US7741519B2 (en) 2007-04-23 2010-06-22 Chemocentryx, Inc. Bis-aryl sulfonamides
PT1562940E (pt) 2002-11-18 2007-07-23 Chemocentryx Inc Sulfonamidas de arilo.
US7420055B2 (en) 2002-11-18 2008-09-02 Chemocentryx, Inc. Aryl sulfonamides
ES2314362T3 (es) * 2003-01-16 2009-03-16 Acadia Pharmaceuticals Inc. Agonistas inversos selectivos de los receptores 2a o 2c de serotonina utilizados como agentes terapeuticos contra enfermedades neurodegenerativas.
EP1644373A1 (en) 2003-06-27 2006-04-12 Janssen Pharmaceutica N.V. Tricyclic delta opioid modulators
WO2005075472A1 (en) 2004-02-03 2005-08-18 Janssen Pharmaceutica, N.V. 3-(diheteroarylnethylene)-8-azabicyclo[3.2.1]octane and 3-(aryl)(heteroaryl)methylene)-8-azabicyclo[3.2.1]octane derivatives
HRP20120343T1 (hr) 2004-08-02 2012-05-31 Astrazeneca Ab Derivati diarilmetil piperazina, njihovi pripravci i njihova uporaba
BRPI0513075A (pt) * 2004-08-05 2008-04-22 Janssen Pharmaceutica Nv moduladores gama-opióides tricìclicos
AU2005319059A1 (en) * 2004-12-22 2006-06-29 Janssen Pharmaceutica N.V. Tricyclic delta-opioid modulators
MX2007007626A (es) * 2004-12-22 2008-01-28 Johnson & Johnson Moduladores delta-opioides triciclicos.
CA2592464A1 (en) * 2004-12-22 2006-06-29 Janssen Pharmaceutica N.V. Tricyclic .delta.-opioid modulators
CA2594347A1 (en) * 2005-01-06 2006-07-13 Janssen Pharmaceutica N.V. Tricyclic d-opioid modulators
TWI449692B (zh) 2005-05-13 2014-08-21 Otsuka Pharma Co Ltd 吡咯烷化合物（三）
JP2008543866A (ja) * 2005-06-16 2008-12-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 三環式オピオイドモジュレーター
JP5219465B2 (ja) * 2006-11-10 2013-06-26 大塚製薬株式会社 医薬

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091096A (en) * 1976-03-19 1978-05-23 Eli Lilly And Company Dinitroanilines for the control of phytopathogens
EG12406A (en) * 1976-08-12 1979-03-31 Janssen Pharmaceutica Nv Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
SE441448B (sv) * 1977-05-23 1985-10-07 Pfizer Sett att framstella hexahydro-gamma-karbolinforeningar
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3563964D1 (en) * 1984-10-16 1988-09-01 Synthelabo Piperidine derivatives, their preparation and their therapeutical application
YU150489A (sh) 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
KR940003491B1 (ko) 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
SE8904298D0 (sv) * 1989-12-21 1989-12-21 Astra Ab New compounds
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
US5854245A (en) * 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
WO1999033806A1 (en) * 1997-12-24 1999-07-08 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor
AU756983B2 (en) 1998-03-10 2003-01-30 Research Triangle Institute Novel opiate compounds, methods of making and methods of use
US6436959B1 (en) 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides

Also Published As

Publication number Publication date
AU738002B2 (en) 2001-09-06
NO993023D0 (no) 1999-06-18
PL188945B1 (pl) 2005-05-31
DE69729115T2 (de) 2005-04-28
PL334370A1 (en) 2000-02-28
US6153626A (en) 2000-11-28
SK283300B6 (sk) 2003-05-02
AU5351398A (en) 1998-07-17
NO313632B1 (no) 2002-11-04
ES2219783T3 (es) 2004-12-01
MY132705A (en) 2007-10-31
HK1023996A1 (en) 2000-09-29
EP0946510A1 (en) 1999-10-06
UA54481C2 (uk) 2003-03-17
JP2001507021A (ja) 2001-05-29
HUP0000613A2 (hu) 2000-09-28
ZA9711049B (en) 1998-06-22
US6399635B1 (en) 2002-06-04
WO1998028270A1 (en) 1998-07-02
BR9713785A (pt) 2000-02-08
CN1241178A (zh) 2000-01-12
CN1539824A (zh) 2004-10-27
EE9900261A (et) 2000-02-15
AR010378A1 (es) 2000-06-07
US6710179B2 (en) 2004-03-23
CA2274117A1 (en) 1998-07-02
ATE266638T1 (de) 2004-05-15
EE03966B1 (et) 2003-02-17
CN1154635C (zh) 2004-06-23
HUP0000613A3 (en) 2002-10-28
NO993023L (no) 1999-08-12
HK1022910A1 (en) 2000-08-25
US20030055045A1 (en) 2003-03-20
EP1428821A1 (en) 2004-06-16
DE69729115D1 (de) 2004-06-17
PT946510E (pt) 2004-08-31
RU2193030C2 (ru) 2002-11-20
IL130536A0 (en) 2000-06-01
CZ220099A3 (cs) 1999-11-17
IS5078A (is) 1999-06-11
ID21662A (id) 1999-07-08
EP0946510B1 (en) 2004-05-12
EP1428821A8 (en) 2005-01-26
TR199901411T2 (xx) 1999-09-21
DK0946510T3 (da) 2004-08-09
SK76399A3 (en) 2000-01-18
KR20000069600A (ko) 2000-11-25
NZ336028A (en) 2001-03-30

Similar Documents

Publication Publication Date Title
SE9604786D0 (sv) New compounds
SE9504661D0 (sv) New compounds
CA2274074A1 (en) Novel compounds with analgesic effect
HU9600834D0 (en) Quinazoline derivatives
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
RU94043772A (ru) Пропинил-диароматические соединения, фармацевтические и косметические составы на их основе
SE9802206D0 (sv) Novel compounds
SE9900961D0 (sv) Novel compounds
DE69523169D1 (de) Verwendung von Mangiferin oder seinen Derivaten zur kosmetischen Anwendung
CY1107391T1 (el) Αρυλσυμπυκνωμενες αζαπολυκυκλικες ενωσεις
BG103399A (en) New heterocycle-substituted benzamides and their application for the treatment of diseases
SE9802208D0 (sv) Novel compounds
DE69716810D1 (de) 2,3-Disubstituierte-(5,6)-heteroarylkondensierte-pyrimidin-4-one
SE0104250D0 (sv) Heterocyclic compounds
PT992509E (pt) Novos derivados macrolidos
ATE219073T1 (de) Benzopyran derivate mit leukotrien- antagonistischer wirkung
ES2160649T3 (es) Nuevos compuestos lactamicos y procedimientos para su preparacion.
DE69530988D1 (de) Benzimidazolderivate mit dopaminerger wirkung
GEP20043227B (en) 5HT1 Antagonists for Antidepressant Therapy
MD502G2 (ro) Derivaţi noi ai adenozinei, procedee de preparare a lor, compoziţii farmaceutice ce le conţin
EA200000242A1 (ru) Применение фанхинона для лечения болезни альцгеймера
SE9802209D0 (sv) Novel compounds
DE69227583D1 (de) Arylmorpholine, herstellung und verwendung
SE9504662D0 (sv) New compounds
UY27587A1 (es) Heterociclos terapéuticos