ES2160649T3 - Nuevos compuestos lactamicos y procedimientos para su preparacion. - Google Patents
Nuevos compuestos lactamicos y procedimientos para su preparacion.Info
- Publication number
- ES2160649T3 ES2160649T3 ES95109191T ES95109191T ES2160649T3 ES 2160649 T3 ES2160649 T3 ES 2160649T3 ES 95109191 T ES95109191 T ES 95109191T ES 95109191 T ES95109191 T ES 95109191T ES 2160649 T3 ES2160649 T3 ES 2160649T3
- Authority
- ES
- Spain
- Prior art keywords
- procedures
- preparation
- compounds
- new dairy
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D421/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D421/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings
- C07D421/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Abstract
LA INVENCION SE REFIERE A LA UTILIZACION DE COMPUESTOS LACTAMO ELEGIDOS COMO SUSTANCIAS ACTIVAS FARMACEUTICAS, NUEVOS COMPUESTOS LACTAMO ASI COMO PROCESO PARA SU ELABORACION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4422237A DE4422237A1 (de) | 1994-06-24 | 1994-06-24 | Verwendung von Lactamverbindungen als pharmazeutische Wirkstoffe |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2160649T3 true ES2160649T3 (es) | 2001-11-16 |
Family
ID=6521476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95109191T Expired - Lifetime ES2160649T3 (es) | 1994-06-24 | 1995-06-14 | Nuevos compuestos lactamicos y procedimientos para su preparacion. |
Country Status (14)
Country | Link |
---|---|
US (1) | US6500845B1 (es) |
EP (1) | EP0688771B1 (es) |
JP (1) | JPH0892092A (es) |
AT (1) | ATE203021T1 (es) |
AU (1) | AU689885B2 (es) |
CA (1) | CA2152432A1 (es) |
DE (2) | DE4422237A1 (es) |
DK (1) | DK0688771T3 (es) |
ES (1) | ES2160649T3 (es) |
GR (1) | GR3036532T3 (es) |
HK (1) | HK1010107A1 (es) |
HU (1) | HUT72600A (es) |
PT (1) | PT688771E (es) |
SI (1) | SI0688771T1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5635517B1 (en) * | 1996-07-24 | 1999-06-29 | Celgene Corp | Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines |
ES2529190T3 (es) * | 1996-07-24 | 2015-02-17 | Celgene Corporation | 2-(2,6-dioxopiperidin-3-il)-ftalimidas sustituidas por amino para reducir los niveles de TNF-alfa |
HU228769B1 (en) * | 1996-07-24 | 2013-05-28 | Celgene Corp | Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha |
PT1308444E (pt) * | 1997-11-18 | 2006-08-31 | Celgene Corp | 2-( 2,6-dioxo-3-fluoropiperidina-3-il )- isoindolinas e a sua utilizacao para reduzir os niveis de tnf |
US5955476A (en) * | 1997-11-18 | 1999-09-21 | Celgene Corporation | Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels |
BR9908811A (pt) * | 1998-03-16 | 2000-12-05 | Celgene Corp | Composto, composição farmacêutica e seu uso no tratamento de mamìferos |
US6673828B1 (en) | 1998-05-11 | 2004-01-06 | Children's Medical Center Corporation | Analogs of 2-Phthalimidinoglutaric acid |
KR100699968B1 (ko) * | 1998-05-11 | 2007-03-28 | 더 칠드런스 메디칼 센터 코포레이션 | 2-프탈이미디노글루타르산 유사체 및 안기오게네시스억제제로서의 이의 용도 |
US7629360B2 (en) * | 1999-05-07 | 2009-12-08 | Celgene Corporation | Methods for the treatment of cachexia and graft v. host disease |
CA2374767C (en) * | 1999-05-20 | 2007-05-15 | Dong Wha Pharm. Ind. Co., Ltd. | Optically active quinoline carboxylic acid derivatives having 7-pyrrolidine substitutes causing optical activity and a process for preparing thereof |
US7182953B2 (en) * | 1999-12-15 | 2007-02-27 | Celgene Corporation | Methods and compositions for the prevention and treatment of atherosclerosis restenosis and related disorders |
EP1389203B8 (en) * | 2001-02-27 | 2010-03-10 | The Governement of the United States of America, represented by The Secretary Department of Health and Human services | Analogs of thalidomide as angiogenesis inhibitors |
CN1867331B (zh) | 2003-09-17 | 2010-05-26 | 美国政府健康及人类服务部 | 作为TNF-α调节剂的沙利度胺类似物 |
US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
CA2648216C (en) * | 2006-04-13 | 2016-06-07 | Michael Gutschow | Tetrahalogenated compounds useful as inhibitors of angiogenesis |
SG192946A1 (en) | 2011-03-11 | 2013-09-30 | Celgene Corp | Solid forms of 3-(5-amino-2methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione, and their pharmaceutical compositions and uses |
US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3705162A (en) * | 1967-07-01 | 1972-12-05 | Gruenenthal Chemie | 4-phthalimidine glutarimides |
DE3048663A1 (de) * | 1980-12-23 | 1982-07-22 | Grünenthal GmbH, 5190 Stolberg | Neue lactamverbindungen, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
DE3827093A1 (de) | 1988-08-10 | 1990-02-15 | Nattermann A & Cie | Verfahren zur herstellung von hochreinem ebselen |
AU1531492A (en) | 1991-02-14 | 1992-09-15 | Rockefeller University, The | Method for controlling abnormal concentration tnf alpha in human tissues |
US5382514A (en) * | 1992-03-31 | 1995-01-17 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | In vivo angiogenesis assay |
US5629327A (en) * | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
-
1994
- 1994-06-24 DE DE4422237A patent/DE4422237A1/de not_active Withdrawn
-
1995
- 1995-06-06 US US08/471,198 patent/US6500845B1/en not_active Expired - Fee Related
- 1995-06-14 ES ES95109191T patent/ES2160649T3/es not_active Expired - Lifetime
- 1995-06-14 EP EP95109191A patent/EP0688771B1/de not_active Expired - Lifetime
- 1995-06-14 DE DE59509395T patent/DE59509395D1/de not_active Expired - Lifetime
- 1995-06-14 DK DK95109191T patent/DK0688771T3/da active
- 1995-06-14 AT AT95109191T patent/ATE203021T1/de not_active IP Right Cessation
- 1995-06-14 PT PT95109191T patent/PT688771E/pt unknown
- 1995-06-14 SI SI9530475T patent/SI0688771T1/xx unknown
- 1995-06-19 HU HU9501801A patent/HUT72600A/hu unknown
- 1995-06-22 CA CA002152432A patent/CA2152432A1/en not_active Abandoned
- 1995-06-23 JP JP7158186A patent/JPH0892092A/ja active Pending
- 1995-06-23 AU AU23230/95A patent/AU689885B2/en not_active Ceased
-
1998
- 1998-09-25 HK HK98110958A patent/HK1010107A1/xx not_active IP Right Cessation
-
2001
- 2001-09-05 GR GR20010401392T patent/GR3036532T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SI0688771T1 (en) | 2001-10-31 |
DE59509395D1 (de) | 2001-08-16 |
ATE203021T1 (de) | 2001-07-15 |
HU9501801D0 (en) | 1995-08-28 |
US6500845B1 (en) | 2002-12-31 |
PT688771E (pt) | 2001-11-30 |
JPH0892092A (ja) | 1996-04-09 |
AU2323095A (en) | 1996-01-11 |
EP0688771B1 (de) | 2001-07-11 |
AU689885B2 (en) | 1998-04-09 |
DK0688771T3 (da) | 2001-09-17 |
HUT72600A (en) | 1996-05-28 |
EP0688771A1 (de) | 1995-12-27 |
CA2152432A1 (en) | 1995-12-25 |
DE4422237A1 (de) | 1996-01-04 |
GR3036532T3 (en) | 2001-12-31 |
HK1010107A1 (en) | 1999-06-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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