ES2162951T3 - Estabilizacion de composiciones de prostaglandina. - Google Patents
Estabilizacion de composiciones de prostaglandina.Info
- Publication number
- ES2162951T3 ES2162951T3 ES95944447T ES95944447T ES2162951T3 ES 2162951 T3 ES2162951 T3 ES 2162951T3 ES 95944447 T ES95944447 T ES 95944447T ES 95944447 T ES95944447 T ES 95944447T ES 2162951 T3 ES2162951 T3 ES 2162951T3
- Authority
- ES
- Spain
- Prior art keywords
- compositions
- prostaglandina
- stabilization
- prostaglandin
- chemical stability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
EL USO DE ACEITES DE RICINO POLIETOXILADOS EN COMPOSICIONES DE PROSTAGLANDINAS MEJORA EN GRAN MEDIDA LA ESTABILIDAD QUIMICA DE LAS PROSTAGLANDINAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/362,677 US5631287A (en) | 1994-12-22 | 1994-12-22 | Storage-stable prostaglandin compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2162951T3 true ES2162951T3 (es) | 2002-01-16 |
Family
ID=23427079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95944447T Expired - Lifetime ES2162951T3 (es) | 1994-12-22 | 1995-12-19 | Estabilizacion de composiciones de prostaglandina. |
Country Status (12)
Country | Link |
---|---|
US (2) | US5631287A (es) |
EP (1) | EP0812198B1 (es) |
JP (3) | JP3631255B2 (es) |
AT (1) | ATE208621T1 (es) |
AU (1) | AU700574B2 (es) |
CA (1) | CA2181172C (es) |
DE (1) | DE69523951T2 (es) |
DK (1) | DK0812198T3 (es) |
ES (1) | ES2162951T3 (es) |
MX (1) | MX9603560A (es) |
PT (1) | PT812198E (es) |
WO (1) | WO1997029752A1 (es) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6011062A (en) * | 1994-12-22 | 2000-01-04 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
AR002194A1 (es) † | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
WO1998050024A1 (en) * | 1997-05-09 | 1998-11-12 | The Mount Sinai School Of Medicine Of The City University Of New York | 8-iso-prostaglandins for glaucoma therapy |
ATE285795T1 (de) * | 1998-07-14 | 2005-01-15 | Alcon Mfg Ltd | Polypropylenbasierte behälter für prostaglandin- enthaltende produkte |
US6235781B1 (en) | 1998-07-14 | 2001-05-22 | Alcon Laboratories, Inc. | Prostaglandin product |
AR020661A1 (es) | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento |
US7678836B2 (en) * | 1999-11-04 | 2010-03-16 | Fxs Ventures, Llc | Method for rendering a contact lens wettable |
US7166730B2 (en) * | 2000-01-27 | 2007-01-23 | Fine Tech Laboratories, Ltd | Process for the preparation of prostaglandin derivatives |
EP1321144B1 (en) * | 2000-09-13 | 2010-12-08 | Santen Pharmaceutical Co., Ltd. | Eye drops |
US7816399B2 (en) | 2001-04-19 | 2010-10-19 | Teika Pharmaceutical Co., Ltd. | Medicines and medicinal kits |
US20060264353A1 (en) * | 2002-03-21 | 2006-11-23 | Maxey Kirk M | Prostaglandin f2alpha analogs and their use in combination with antimicrobial proteins for the treatment of glaucoma and intraocular hypertension |
US20040079671A1 (en) * | 2002-08-29 | 2004-04-29 | Paramita Bandyopadhyay | Medicinal product packaging |
AU2003261981A1 (en) * | 2002-09-09 | 2004-03-29 | Santen Pharmaceutical Co., Ltd. | Transparent eye drops containing latanoprost |
DE602004023106D1 (de) | 2003-11-07 | 2009-10-22 | Senju Pharma Co | Pharmazeutische zusammensetzung mit prostaglandin |
GB0329620D0 (en) * | 2003-12-22 | 2004-01-28 | Pharmagene Lab Ltd | EP2 receptor agonists |
PL1759702T3 (pl) * | 2004-05-26 | 2009-06-30 | Bayardo Arturo Jimenez | Sposób wytwarzania roztworu latanoprostu do oczu oraz roztwór otrzymany tym sposobem |
ATE412400T1 (de) * | 2004-11-09 | 2008-11-15 | Novagali Pharma Sa | Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential |
GB0501192D0 (en) * | 2005-01-20 | 2005-03-02 | Resolution Chemicals Ltd | Stable prostaglandin-containing compositions |
WO2007015510A1 (ja) * | 2005-08-02 | 2007-02-08 | Santen Pharmaceutical Co., Ltd. | 熱的に不安定な薬物の分解抑制方法 |
CN104224704A (zh) * | 2006-03-13 | 2014-12-24 | 株式会社·R-技术上野 | 水性组合物 |
WO2007111806A2 (en) | 2006-03-23 | 2007-10-04 | Massachusetts Eye And Ear Infirmary | Cyclopentane heptanoic acid compounds for reducing body fat |
US20080095863A1 (en) * | 2006-10-24 | 2008-04-24 | Alcon Manufacturing Ltd. | 2-pyrrolidone derivatives for preservation of ophthalmic, otic and nasal compositions |
EP2123278B1 (en) | 2007-02-07 | 2013-01-09 | Teika Pharmaceutical Co., Ltd. | Eye drop preparation comprising latanoprost |
EP1985298A1 (en) * | 2007-04-24 | 2008-10-29 | Azad Pharma AG | Ophtalmic oil-in-water emulsions containing prostaglandins |
WO2009084021A2 (en) * | 2007-10-16 | 2009-07-09 | Sun Pharma Advanced Research Company Limited | Novel ophthalmic compositions |
EP2077105A1 (en) | 2008-01-02 | 2009-07-08 | Novagali Pharma SA | Ophthalmic Micellar Compositions with Enhanced Stability |
EP2077104A1 (en) | 2008-01-02 | 2009-07-08 | Novagali Pharma SA | Micellar compositions with ophtalmic applications |
US20090232763A1 (en) | 2008-03-17 | 2009-09-17 | Kabra Bhagwati P | Aqueous pharmaceutical compositions containing borate-polyol complexes |
TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
JP2009256281A (ja) * | 2008-04-21 | 2009-11-05 | Teika Seiyaku Kk | イソプロピルウノプロストン含有点眼剤組成物 |
EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
US20110293549A1 (en) | 2009-02-03 | 2011-12-01 | Athena Cosmetics, Inc. | Composition, method and kit for enhancing hair |
EP2228058A1 (en) | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Anionic oil-in-water emulsion containing prostaglandins and uses thereof |
TWI489997B (zh) * | 2009-06-19 | 2015-07-01 | Alcon Res Ltd | 含有硼酸-多元醇錯合物之水性藥學組成物 |
EP2498768A1 (en) * | 2009-11-11 | 2012-09-19 | Micro Labs Limited | Pharmaceutical combination of prostaglandin compound and nsaid for the treatment of glaucoma and ocular hypertension |
EP2389939A1 (en) * | 2010-05-28 | 2011-11-30 | Novagali Pharma S.A. | Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions |
FR2961694B1 (fr) | 2010-06-29 | 2013-01-25 | Thea Lab | Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur |
EP2452669A1 (en) | 2010-10-29 | 2012-05-16 | Omnivision GmbH | Ophthalmic composition |
JP2014500275A (ja) | 2010-12-06 | 2014-01-09 | フォリカ,インコーポレイテッド | 禿頭症を治療するため、および毛髪の成長を促進するための方法 |
ES2687494T3 (es) | 2011-01-19 | 2018-10-25 | Topokine Therapeutics, Inc. | Métodos y composiciones para reducir la grasa corporal |
US8426471B1 (en) | 2011-12-19 | 2013-04-23 | Topokine Therapeutics, Inc. | Methods and compositions for reducing body fat and adipocytes |
ITRM20120036A1 (it) * | 2012-02-02 | 2013-08-03 | Robert Davis Steigerwalt Jr | Applicazione transdermica di prostaglandina e1 per il trattamento dell¿ischemia oculare. |
CA2869676C (en) | 2012-11-21 | 2015-06-23 | Topokine Therapeutics, Inc. | Uses and compositions comprising a thiazolidinedione and oleic acid for locally increasing subcutaneous fat |
NO2753788T3 (es) | 2013-05-10 | 2018-06-16 | ||
WO2014186504A1 (en) | 2013-05-15 | 2014-11-20 | Topokine Therapeutics, Inc. | Methods and compositions for topical delivery of prostaglandins to subcutaneous fat |
TWI612960B (zh) * | 2014-01-10 | 2018-02-01 | Santen Pharmaceutical Co Ltd | 吡啶基胺基乙酸化合物及含聚氧乙烯蓖麻油之醫藥組成物 |
AU2015205179B2 (en) | 2014-01-10 | 2019-09-19 | Santen Pharmaceutical Co., Ltd. | Pharmaceutical composition containing pyridylamino acetic acid compound |
WO2015200425A1 (en) | 2014-06-27 | 2015-12-30 | Topokine Therapeutics, Inc. | Topical dosage regimen |
CA2999988C (en) | 2015-09-27 | 2024-06-11 | Follica, Inc. | Needling device and drug applicator |
EP3883562A4 (en) | 2018-11-21 | 2022-08-03 | Tremeau Pharmaceuticals, Inc. | PURIFIED FORMS OF ROFECOXIB AND METHODS OF MAKING AND USING |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2526938C2 (de) * | 1975-02-14 | 1982-04-22 | F. Hoffmann-La Roche & Co. AG, 4002 Basel | Vitaminpräparate |
JPS6046094B2 (ja) * | 1977-06-01 | 1985-10-14 | 科研製薬株式会社 | 安定化されたプロスタグランジンe類粉末製剤 |
JPS59216820A (ja) * | 1983-05-20 | 1984-12-06 | Taisho Pharmaceut Co Ltd | プロスタグランジン脂肪乳剤 |
DE3347128A1 (de) * | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 9-halogen-(delta)(pfeil hoch)2(pfeil hoch)-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3510978A1 (de) * | 1985-03-22 | 1986-09-25 | Schering AG, Berlin und Bergkamen, 1000 Berlin | Neue 9-halogenprostaglandine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
JP2597629B2 (ja) * | 1988-02-26 | 1997-04-09 | 株式会社 上野製薬応用研究所 | 13,14−ジヒドロ−15−ケトプロスタグランジン類の安定化 |
US4960799A (en) * | 1988-09-13 | 1990-10-02 | Ciba-Geigy Corporation | Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use |
JPH0669966B2 (ja) * | 1989-07-05 | 1994-09-07 | 株式会社ミドリ十字 | 血管造影補助剤 |
JPH03101622A (ja) * | 1989-09-11 | 1991-04-26 | Green Cross Corp:The | 肝炎予防治療剤 |
JP2785981B2 (ja) * | 1989-11-20 | 1998-08-13 | 株式会社資生堂 | 乳化組成物 |
CA2031469A1 (en) * | 1989-12-28 | 1991-06-29 | Larry A. Wheeler | Use of inclusion complexes of prostaglandins with cyclodextrins in the treatment of ocular hypertension |
JP3256997B2 (ja) * | 1990-08-30 | 2002-02-18 | 千寿製薬株式会社 | 安定な水性製剤 |
DE69311361T2 (de) * | 1992-10-13 | 1998-01-08 | Alcon Lab Inc | Zusammensetzungen zur behandlung von glaukoma die prostaglandine und clonidinderivate enthalten |
US5744155A (en) * | 1993-08-13 | 1998-04-28 | Friedman; Doron | Bioadhesive emulsion preparations for enhanced drug delivery |
TW406020B (en) * | 1993-09-29 | 2000-09-21 | Bristol Myers Squibb Co | Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent |
AU687906B2 (en) * | 1993-12-15 | 1998-03-05 | Alcon Laboratories, Inc. | Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension |
-
1994
- 1994-12-22 US US08/362,677 patent/US5631287A/en not_active Expired - Lifetime
-
1995
- 1995-12-19 CA CA002181172A patent/CA2181172C/en not_active Expired - Lifetime
- 1995-12-19 DE DE69523951T patent/DE69523951T2/de not_active Expired - Lifetime
- 1995-12-19 AU AU46495/96A patent/AU700574B2/en not_active Expired
- 1995-12-19 PT PT95944447T patent/PT812198E/pt unknown
- 1995-12-19 JP JP52494296A patent/JP3631255B2/ja not_active Expired - Lifetime
- 1995-12-19 WO PCT/US1995/017086 patent/WO1997029752A1/en active IP Right Grant
- 1995-12-19 AT AT95944447T patent/ATE208621T1/de active
- 1995-12-19 EP EP95944447A patent/EP0812198B1/en not_active Expired - Lifetime
- 1995-12-19 DK DK95944447T patent/DK0812198T3/da active
- 1995-12-19 ES ES95944447T patent/ES2162951T3/es not_active Expired - Lifetime
-
1996
- 1996-08-21 MX MX9603560A patent/MX9603560A/es unknown
- 1996-10-29 US US08/738,629 patent/US5849792A/en not_active Expired - Lifetime
-
2004
- 2004-10-15 JP JP2004302299A patent/JP2005015498A/ja active Pending
-
2009
- 2009-11-24 JP JP2009266859A patent/JP2010043131A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP3631255B2 (ja) | 2005-03-23 |
US5631287A (en) | 1997-05-20 |
JPH11500122A (ja) | 1999-01-06 |
US5849792A (en) | 1998-12-15 |
JP2005015498A (ja) | 2005-01-20 |
PT812198E (pt) | 2002-02-28 |
JP2010043131A (ja) | 2010-02-25 |
DE69523951T2 (de) | 2002-04-04 |
MX9603560A (es) | 1998-01-31 |
AU4649596A (en) | 1997-09-02 |
CA2181172A1 (en) | 1996-06-23 |
CA2181172C (en) | 2003-04-29 |
AU700574B2 (en) | 1999-01-07 |
DK0812198T3 (da) | 2002-03-18 |
ATE208621T1 (de) | 2001-11-15 |
DE69523951D1 (de) | 2001-12-20 |
EP0812198A1 (en) | 1997-12-17 |
EP0812198B1 (en) | 2001-11-14 |
WO1997029752A1 (en) | 1997-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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