DK0688771T3 - Anvendelse af lactamforbindelser som farmaceutiske aktivstoffer - Google Patents
Anvendelse af lactamforbindelser som farmaceutiske aktivstofferInfo
- Publication number
- DK0688771T3 DK0688771T3 DK95109191T DK95109191T DK0688771T3 DK 0688771 T3 DK0688771 T3 DK 0688771T3 DK 95109191 T DK95109191 T DK 95109191T DK 95109191 T DK95109191 T DK 95109191T DK 0688771 T3 DK0688771 T3 DK 0688771T3
- Authority
- DK
- Denmark
- Prior art keywords
- active substances
- pharmaceutical active
- lactam compounds
- lactam
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D421/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D421/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings
- C07D421/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4422237A DE4422237A1 (de) | 1994-06-24 | 1994-06-24 | Verwendung von Lactamverbindungen als pharmazeutische Wirkstoffe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0688771T3 true DK0688771T3 (da) | 2001-09-17 |
Family
ID=6521476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95109191T DK0688771T3 (da) | 1994-06-24 | 1995-06-14 | Anvendelse af lactamforbindelser som farmaceutiske aktivstoffer |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6500845B1 (es) |
| EP (1) | EP0688771B1 (es) |
| JP (1) | JPH0892092A (es) |
| AT (1) | ATE203021T1 (es) |
| AU (1) | AU689885B2 (es) |
| CA (1) | CA2152432A1 (es) |
| DE (2) | DE4422237A1 (es) |
| DK (1) | DK0688771T3 (es) |
| ES (1) | ES2160649T3 (es) |
| GR (1) | GR3036532T3 (es) |
| HK (1) | HK1010107A1 (es) |
| HU (1) | HUT72600A (es) |
| PT (1) | PT688771E (es) |
| SI (1) | SI0688771T1 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635517B1 (en) * | 1996-07-24 | 1999-06-29 | Celgene Corp | Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines |
| ES2339425T3 (es) * | 1996-07-24 | 2010-05-20 | Celgene Corporation | 2-(2,6-dioxopiperidin-3-il)-ftalimidas y -1-oxoisoindolinas sustituidas y procedimiento para reducir los niveles de tnf-alfa. |
| HU228769B1 (en) * | 1996-07-24 | 2013-05-28 | Celgene Corp | Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha |
| ES2192342T3 (es) * | 1997-11-18 | 2003-10-01 | Celgene Corp | 2-(2,6-dioxo-3-fluoropiperidin-3-il)-isoindolinas sustituidas y su uso para reducir los niveles de tnfalfa. |
| US5955476A (en) * | 1997-11-18 | 1999-09-21 | Celgene Corporation | Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels |
| CZ299253B6 (cs) * | 1998-03-16 | 2008-05-28 | Celgene Corporation | Isoindolinový derivát, jeho použití pro výrobu léciva a farmaceutická kompozice tento derivát obsahující |
| JP2002514578A (ja) * | 1998-05-11 | 2002-05-21 | エントレメッド インコーポレイテッド | ２−フタルイミジノグルタル酸の類似体および血管新生の阻害剤としてのそれらの使用 |
| US6673828B1 (en) | 1998-05-11 | 2004-01-06 | Children's Medical Center Corporation | Analogs of 2-Phthalimidinoglutaric acid |
| US7629360B2 (en) * | 1999-05-07 | 2009-12-08 | Celgene Corporation | Methods for the treatment of cachexia and graft v. host disease |
| ES2296618T3 (es) * | 1999-05-20 | 2008-05-01 | Dong Wha Pharmaceutical Industrial Co. Ltd. | Derivados opticamente activos de acidos quinolin-carboxilicos que tienen sustituyentes de 7-pirrolidina que provocan actividad optica y un procedimiento para la preparacion de estos. |
| US7182953B2 (en) | 1999-12-15 | 2007-02-27 | Celgene Corporation | Methods and compositions for the prevention and treatment of atherosclerosis restenosis and related disorders |
| WO2002068414A2 (en) * | 2001-02-27 | 2002-09-06 | The Governement Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
| JP4943845B2 (ja) | 2003-09-17 | 2012-05-30 | ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ | サリドマイド類似体 |
| US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
| AU2007238785B2 (en) * | 2006-04-13 | 2013-02-07 | Agnieszka Ambrozak | Tetrahalogenated compounds useful as inhibitors of angiogenesis |
| HUE037955T2 (hu) | 2011-03-11 | 2018-09-28 | Celgene Corp | A 3-(5-amino-2-metil-4-oxo-4H-kinazolin-3-il)- piperidin-2,6-dion szilárd halmazállapotú formái, valamint gyógyászati készítményei és felhasználása |
| US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3705162A (en) * | 1967-07-01 | 1972-12-05 | Gruenenthal Chemie | 4-phthalimidine glutarimides |
| DE3048663A1 (de) * | 1980-12-23 | 1982-07-22 | Grünenthal GmbH, 5190 Stolberg | Neue lactamverbindungen, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
| DE3827093A1 (de) | 1988-08-10 | 1990-02-15 | Nattermann A & Cie | Verfahren zur herstellung von hochreinem ebselen |
| AU1531492A (en) | 1991-02-14 | 1992-09-15 | Rockefeller University, The | Method for controlling abnormal concentration tnf alpha in human tissues |
| US5382514A (en) * | 1992-03-31 | 1995-01-17 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | In vivo angiogenesis assay |
| US5629327A (en) | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
-
1994
- 1994-06-24 DE DE4422237A patent/DE4422237A1/de not_active Withdrawn
-
1995
- 1995-06-06 US US08/471,198 patent/US6500845B1/en not_active Expired - Fee Related
- 1995-06-14 PT PT95109191T patent/PT688771E/pt unknown
- 1995-06-14 SI SI9530475T patent/SI0688771T1/xx unknown
- 1995-06-14 EP EP95109191A patent/EP0688771B1/de not_active Expired - Lifetime
- 1995-06-14 DE DE59509395T patent/DE59509395D1/de not_active Expired - Lifetime
- 1995-06-14 AT AT95109191T patent/ATE203021T1/de not_active IP Right Cessation
- 1995-06-14 ES ES95109191T patent/ES2160649T3/es not_active Expired - Lifetime
- 1995-06-14 DK DK95109191T patent/DK0688771T3/da active
- 1995-06-19 HU HU9501801A patent/HUT72600A/hu unknown
- 1995-06-22 CA CA002152432A patent/CA2152432A1/en not_active Abandoned
- 1995-06-23 JP JP7158186A patent/JPH0892092A/ja active Pending
- 1995-06-23 AU AU23230/95A patent/AU689885B2/en not_active Ceased
-
1998
- 1998-09-25 HK HK98110958A patent/HK1010107A1/xx not_active IP Right Cessation
-
2001
- 2001-09-05 GR GR20010401392T patent/GR3036532T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2152432A1 (en) | 1995-12-25 |
| ES2160649T3 (es) | 2001-11-16 |
| JPH0892092A (ja) | 1996-04-09 |
| HUT72600A (en) | 1996-05-28 |
| PT688771E (pt) | 2001-11-30 |
| DE59509395D1 (de) | 2001-08-16 |
| HK1010107A1 (en) | 1999-06-11 |
| HU9501801D0 (en) | 1995-08-28 |
| EP0688771A1 (de) | 1995-12-27 |
| DE4422237A1 (de) | 1996-01-04 |
| GR3036532T3 (en) | 2001-12-31 |
| EP0688771B1 (de) | 2001-07-11 |
| US6500845B1 (en) | 2002-12-31 |
| AU2323095A (en) | 1996-01-11 |
| SI0688771T1 (en) | 2001-10-31 |
| AU689885B2 (en) | 1998-04-09 |
| ATE203021T1 (de) | 2001-07-15 |
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