SE9501939D0 - DNA molecules for expression of polypeptides - Google Patents
DNA molecules for expression of polypeptidesInfo
- Publication number
- SE9501939D0 SE9501939D0 SE9501939A SE9501939A SE9501939D0 SE 9501939 D0 SE9501939 D0 SE 9501939D0 SE 9501939 A SE9501939 A SE 9501939A SE 9501939 A SE9501939 A SE 9501939A SE 9501939 D0 SE9501939 D0 SE 9501939D0
- Authority
- SE
- Sweden
- Prior art keywords
- polypeptide
- pichia pastoris
- coding
- expression
- region
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108020004414 DNA Proteins 0.000 abstract 3
- 241000235058 Komagataella pastoris Species 0.000 abstract 3
- 102100035687 Bile salt-activated lipase Human genes 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 2
- 108010087173 bile salt-stimulated lipase Proteins 0.000 abstract 2
- 108010025188 Alcohol oxidase Proteins 0.000 abstract 1
- 108091026890 Coding region Proteins 0.000 abstract 1
- 101000715643 Homo sapiens Bile salt-activated lipase Proteins 0.000 abstract 1
- 108700026244 Open Reading Frames Proteins 0.000 abstract 1
- 108010076504 Protein Sorting Signals Proteins 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 102000052905 human CEL Human genes 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (26)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9501939A SE9501939D0 (sv) | 1995-05-24 | 1995-05-24 | DNA molecules for expression of polypeptides |
| SK1256-97A SK125697A3 (en) | 1995-03-23 | 1996-03-12 | A dna molecule for expression of bile salt-stimulated lipase (bssl) |
| RU97117367/13A RU2157847C2 (ru) | 1995-05-24 | 1996-03-12 | Молекула днк для экспрессии, стимулируемой солями желчи липазы (bssl) |
| TR97/01010T TR199701010T1 (xx) | 1995-05-24 | 1996-03-12 | Safra tuzu stim�lasyonlu lipazin ekspresyonu i�in dna. |
| CZ972973A CZ297397A3 (cs) | 1995-05-24 | 1996-03-12 | DNA molekula pro expresi žlučovými solemi stimulované lipasy (BSSL) |
| BR9607920A BR9607920A (pt) | 1995-03-23 | 1996-03-12 | Molécula de dna vetor de expressão replicável células hospedeiras do gênero pichia e processo para a produção de um polipeptídeo que é uma bssl humana |
| PL96322848A PL322848A1 (en) | 1995-05-24 | 1996-03-12 | Dna molecule for expression of bile salt stimulated lipase (bssl) |
| CN96194083A CN1185812A (zh) | 1995-05-24 | 1996-03-12 | 表达胆汁盐刺激脂酶(bssl)的dna分子 |
| JP08535592A JP2000510683A (ja) | 1995-05-24 | 1996-03-12 | 胆汁塩刺激リパーゼ(bssl)発現のためのdna分子 |
| PCT/SE1996/000318 WO1996037622A1 (en) | 1995-05-24 | 1996-03-12 | A dna molecule for expression of bile salt-stimulated lipase (bssl) |
| EE9700321A EE9700321A (et) | 1995-05-24 | 1996-03-12 | DNA molekul sapphapete sooladega stimuleeritud lipaasi ekspressiooniks |
| HU9802388A HUP9802388A3 (en) | 1995-05-24 | 1996-03-12 | A dna molecule for expression of bile salt-stimulated lipase (bssl) |
| KR1019970706642A KR19980703238A (ko) | 1995-03-23 | 1996-03-12 | 답즙산염-자극 리파제(bssl)의 발현을 위한 dna 분자 |
| AU51656/96A AU5165696A (en) | 1995-05-24 | 1996-03-12 | A dna molecule for expression of bile salt-stimulated lipase (bssl) |
| IE960211A IE960211A1 (en) | 1995-03-23 | 1996-03-12 | Dna molecules for expression of polypeptides |
| EP96908415A EP0832257A1 (en) | 1995-05-24 | 1996-03-12 | A dna molecule for expression of bile salt-stimulated lipase (bssl) |
| AU48033/96A AU715297B2 (en) | 1995-03-23 | 1996-03-13 | DNA molecules for expression of polypeptides |
| NZ286234A NZ286234A (en) | 1995-03-23 | 1996-03-21 | Expression of recombinant bile salt-stimulated lipase (bssl) |
| CA002172447A CA2172447A1 (en) | 1995-03-23 | 1996-03-22 | Dna molecules for expression of polypeptides |
| GB9606023A GB2299085B (en) | 1995-03-23 | 1996-03-22 | Expression of bile salt-stimulated lipase in the yeast Pichia |
| AR33588496A AR001410A1 (es) | 1995-03-23 | 1996-03-22 | Moleculas de adn para la expresión de polipeptidos, un vector que las contiene, celulas huesped y procedimiento para la producción de un polipeptido. |
| TW085104253A TW434314B (en) | 1995-05-24 | 1996-04-10 | DNA molecules for expression of polypeptides |
| IL11833596A IL118335A0 (en) | 1995-05-24 | 1996-05-20 | DNA molecules for expression of polypeptides |
| NO974318A NO974318L (no) | 1995-03-23 | 1997-09-19 | DNA-molekyl for ekspresjon av gallesaltstimulert lipase (BSSL) |
| HK98111871.4A HK1011048B (en) | 1995-03-23 | 1998-11-10 | Expression of bile salt-stimulated lipase in the yeast pichia |
| US09/418,176 US20030040040A1 (en) | 1995-03-23 | 1999-10-13 | Dna molecules for expression of bile salt-stimulated lipase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9501939A SE9501939D0 (sv) | 1995-05-24 | 1995-05-24 | DNA molecules for expression of polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9501939D0 true SE9501939D0 (sv) | 1995-05-24 |
Family
ID=20398427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9501939A SE9501939D0 (sv) | 1995-03-23 | 1995-05-24 | DNA molecules for expression of polypeptides |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0832257A1 (cs) |
| JP (1) | JP2000510683A (cs) |
| KR (1) | KR19980703238A (cs) |
| CN (1) | CN1185812A (cs) |
| AU (1) | AU5165696A (cs) |
| CZ (1) | CZ297397A3 (cs) |
| EE (1) | EE9700321A (cs) |
| HU (1) | HUP9802388A3 (cs) |
| IL (1) | IL118335A0 (cs) |
| PL (1) | PL322848A1 (cs) |
| RU (1) | RU2157847C2 (cs) |
| SE (1) | SE9501939D0 (cs) |
| TR (1) | TR199701010T1 (cs) |
| TW (1) | TW434314B (cs) |
| WO (1) | WO1996037622A1 (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001255501A1 (en) * | 2000-04-21 | 2001-11-07 | Monsanto Technology Llc | Blood-pressure reducing polypeptides containing vpp derived from microorganisms |
| KR100717353B1 (ko) * | 2006-04-12 | 2007-05-11 | 한국생명공학연구원 | 피키아 파스토리스 유래의 자동 유도성 nps 프로모터 및이를 이용한 이종 단백질의 제조방법 |
| CN103952386A (zh) * | 2014-03-31 | 2014-07-30 | 四川农业大学 | 利用毕赤酵母高效分泌表达重组猪胰腺脂肪酶ppl的方法 |
| RU2697218C1 (ru) * | 2018-07-11 | 2019-08-13 | федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (национальный исследовательский университет)" | Использование сигнальных пептидов митохондриальной локализации для увеличения уровня гетерологической экспрессии белков в P.pastoris и S.cerevisiae |
| CA3146193A1 (en) * | 2019-07-12 | 2021-01-21 | Lipum Ab | Novel bssl antibodies |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5200183A (en) * | 1987-11-19 | 1993-04-06 | Oklahoma Medical Research Foundation | Recombinant bile salt activated lipases |
| NO177065C (no) * | 1988-09-26 | 1995-07-12 | Labofina Sa | Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym |
| EP0438200B1 (en) * | 1990-01-16 | 2002-07-17 | Centro De Ingenieria Genetica Y Biotecnologia | Method for the expression of heterologous genes in the yeast Pichia pastoris, expression vectors and transformed microorganisms |
| EP0443063A1 (en) * | 1990-02-22 | 1991-08-28 | Henkel Research Corporation | Pseudomonas lipase gene, vectors for the expression thereof, production of the lipase by transformed microorganisms and uses of this enzyme |
| WO1991016422A1 (de) * | 1990-04-14 | 1991-10-31 | Kali-Chemie Aktiengesellschaft | Alkalische bacillus-lipasen, hierfür codierende dna-sequenzen sowie bacilli, die diese lipasen produzieren |
| JPH074256B2 (ja) * | 1990-10-31 | 1995-01-25 | 栗田工業株式会社 | リパーゼの活性発現を調節する遺伝子、ベクターおよびリパーゼの生産方法 |
| IS4130A (is) * | 1993-03-01 | 1994-09-02 | Ab Astra | Ný fjölpeptíð |
-
1995
- 1995-05-24 SE SE9501939A patent/SE9501939D0/xx unknown
-
1996
- 1996-03-12 EP EP96908415A patent/EP0832257A1/en not_active Withdrawn
- 1996-03-12 HU HU9802388A patent/HUP9802388A3/hu unknown
- 1996-03-12 WO PCT/SE1996/000318 patent/WO1996037622A1/en not_active Ceased
- 1996-03-12 CZ CZ972973A patent/CZ297397A3/cs unknown
- 1996-03-12 KR KR1019970706642A patent/KR19980703238A/ko not_active Ceased
- 1996-03-12 RU RU97117367/13A patent/RU2157847C2/ru not_active IP Right Cessation
- 1996-03-12 JP JP08535592A patent/JP2000510683A/ja not_active Abandoned
- 1996-03-12 AU AU51656/96A patent/AU5165696A/en not_active Abandoned
- 1996-03-12 PL PL96322848A patent/PL322848A1/xx unknown
- 1996-03-12 CN CN96194083A patent/CN1185812A/zh active Pending
- 1996-03-12 EE EE9700321A patent/EE9700321A/xx unknown
- 1996-03-12 TR TR97/01010T patent/TR199701010T1/xx unknown
- 1996-04-10 TW TW085104253A patent/TW434314B/zh active
- 1996-05-20 IL IL11833596A patent/IL118335A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EE9700321A (et) | 1998-06-15 |
| CN1185812A (zh) | 1998-06-24 |
| CZ297397A3 (cs) | 1998-03-18 |
| HUP9802388A2 (hu) | 1999-02-01 |
| TW434314B (en) | 2001-05-16 |
| HUP9802388A3 (en) | 2000-10-30 |
| JP2000510683A (ja) | 2000-08-22 |
| TR199701010T1 (xx) | 1998-01-21 |
| IL118335A0 (en) | 1996-09-12 |
| PL322848A1 (en) | 1998-02-16 |
| EP0832257A1 (en) | 1998-04-01 |
| WO1996037622A1 (en) | 1996-11-28 |
| KR19980703238A (ko) | 1998-10-15 |
| RU2157847C2 (ru) | 2000-10-20 |
| AU5165696A (en) | 1996-12-11 |
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