SE9102074D0 - Tomour antigen specific antibody - Google Patents

Tomour antigen specific antibody

Info

Publication number
SE9102074D0
SE9102074D0 SE9102074A SE9102074A SE9102074D0 SE 9102074 D0 SE9102074 D0 SE 9102074D0 SE 9102074 A SE9102074 A SE 9102074A SE 9102074 A SE9102074 A SE 9102074A SE 9102074 D0 SE9102074 D0 SE 9102074D0
Authority
SE
Sweden
Prior art keywords
tomour
antibody
specific antibody
antigen specific
antigen
Prior art date
Application number
SE9102074A
Other languages
English (en)
Swedish (sv)
Inventor
L G Lindholm
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE9102074A priority Critical patent/SE9102074D0/xx
Publication of SE9102074D0 publication Critical patent/SE9102074D0/xx
Priority to IL10239092A priority patent/IL102390A/en
Priority to PCT/SE1992/000495 priority patent/WO1993001302A1/en
Priority to AT92850166T priority patent/ATE171193T1/de
Priority to DE69226990T priority patent/DE69226990T2/de
Priority to JP17584892A priority patent/JP3194020B2/ja
Priority to ES92850166T priority patent/ES2124250T3/es
Priority to CA002073124A priority patent/CA2073124C/en
Priority to AU19425/92A priority patent/AU658198B2/en
Priority to PCT/SE1992/000502 priority patent/WO1993001303A1/en
Priority to AU22920/92A priority patent/AU2292092A/en
Priority to KR1019930704117A priority patent/KR100246681B1/ko
Priority to NZ243435A priority patent/NZ243435A/en
Priority to HU9400011A priority patent/HU218084B/hu
Priority to IE922188A priority patent/IE80841B1/en
Priority to EP92850166A priority patent/EP0521842B1/en
Priority to DK92850166T priority patent/DK0521842T3/da
Priority to NO19934777A priority patent/NO315472B1/no
Priority to FI935970A priority patent/FI109207B/fi
Priority to EE9400328A priority patent/EE03031B1/xx
Priority to US08/438,123 priority patent/US5552293A/en
Priority to HU95P/P00289P priority patent/HU211512A9/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1063—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from stomach or intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1057—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from liver or pancreas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SE9102074A 1991-07-03 1991-07-03 Tomour antigen specific antibody SE9102074D0 (sv)

Priority Applications (22)

Application Number Priority Date Filing Date Title
SE9102074A SE9102074D0 (sv) 1991-07-03 1991-07-03 Tomour antigen specific antibody
IL10239092A IL102390A (en) 1991-07-03 1992-07-02 Tumour antigen specific monoclonal antibody its use and cell line producing the antibody and pharmaceutical compositions containing said antibody
PCT/SE1992/000495 WO1993001302A1 (en) 1991-07-03 1992-07-02 Tumor, carbohydrate antigen specific monoclonal antibody and cell line
DK92850166T DK0521842T3 (da) 1991-07-03 1992-07-03 Tumorantigenspecifikt antistof
AU22920/92A AU2292092A (en) 1991-07-03 1992-07-03 Tumor, carbohydrate antigen specific monoclonal antibody and cell line
NZ243435A NZ243435A (en) 1991-07-03 1992-07-03 Monoclonal antibody specific for a tumour antigen, its use and the cell line responsible for its production
JP17584892A JP3194020B2 (ja) 1991-07-03 1992-07-03 腫瘍抗原特異的抗体、それを含む医薬組成物およびその抗体を産生する細胞系
ES92850166T ES2124250T3 (es) 1991-07-03 1992-07-03 Anticuerpo especifico para un antigeno tumoral.
CA002073124A CA2073124C (en) 1991-07-03 1992-07-03 Tumor antigen specific antibody
AU19425/92A AU658198B2 (en) 1991-07-03 1992-07-03 Tumour antigen specific antibody, its use and cell in line producing the antibody
PCT/SE1992/000502 WO1993001303A1 (en) 1991-07-03 1992-07-03 Tumor, carbohydrate antigen specific monoclonal antibody and cell line
AT92850166T ATE171193T1 (de) 1991-07-03 1992-07-03 Tumorantigen-spezifischer antikörper
KR1019930704117A KR100246681B1 (ko) 1991-07-03 1992-07-03 종양, 탄수화물 항원에 특이한 모노클로날 항체 및 세포계
DE69226990T DE69226990T2 (de) 1991-07-03 1992-07-03 Tumorantigen-spezifischer Antikörper
HU9400011A HU218084B (hu) 1991-07-03 1992-07-03 Daganatokra specifikus monoklonális antitest és sejtvonal, valamint ezeket tartalmazó gyógyászati készítmények
IE922188A IE80841B1 (en) 1991-07-03 1992-07-03 Tumor antigen specific antibody
EP92850166A EP0521842B1 (en) 1991-07-03 1992-07-03 Tumor antigen specific antibody
NO19934777A NO315472B1 (no) 1991-07-03 1993-12-22 Tumor, karbohydratantigen spesifikt monoklonalt antistoff og cellelinje, farmasöytisk sammensetning og fremgangsmåte for invitro diagnostikk
FI935970A FI109207B (fi) 1991-07-03 1993-12-31 Tuumori/hiilihydraattiantigeenispesifinen monoklonaalinen vasta-aine ja solulinja
EE9400328A EE03031B1 (et) 1991-07-03 1994-11-16 Kasvaja süsivesik-antigeeni spetsiifiline monokloonne antikeha, meetod in vitro diagnostikaks ja farmatseutilised kompositsioonid
US08/438,123 US5552293A (en) 1991-07-03 1995-05-08 Tumor antigen specific antibody
HU95P/P00289P HU211512A9 (en) 1991-07-03 1995-06-20 Tumor antigen specific antibody and cell line, and pharmaceutical composition comprising them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9102074A SE9102074D0 (sv) 1991-07-03 1991-07-03 Tomour antigen specific antibody

Publications (1)

Publication Number Publication Date
SE9102074D0 true SE9102074D0 (sv) 1991-07-03

Family

ID=20383243

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9102074A SE9102074D0 (sv) 1991-07-03 1991-07-03 Tomour antigen specific antibody

Country Status (19)

Country Link
US (1) US5552293A (enExample)
EP (1) EP0521842B1 (enExample)
JP (1) JP3194020B2 (enExample)
KR (1) KR100246681B1 (enExample)
AT (1) ATE171193T1 (enExample)
AU (2) AU658198B2 (enExample)
CA (1) CA2073124C (enExample)
DE (1) DE69226990T2 (enExample)
DK (1) DK0521842T3 (enExample)
EE (1) EE03031B1 (enExample)
ES (1) ES2124250T3 (enExample)
FI (1) FI109207B (enExample)
HU (2) HU218084B (enExample)
IE (1) IE80841B1 (enExample)
IL (1) IL102390A (enExample)
NO (1) NO315472B1 (enExample)
NZ (1) NZ243435A (enExample)
SE (1) SE9102074D0 (enExample)
WO (2) WO1993001302A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9402430L (sv) 1994-07-11 1996-01-12 Pharmacia Ab Konjugat mellan modifierat superantigen och en målsökande förening samt användning av konjugaten
SE9601245D0 (sv) 1996-03-29 1996-03-29 Pharmacia Ab Chimeric superantigens and their use
TW517061B (en) 1996-03-29 2003-01-11 Pharmacia & Amp Upjohn Ab Modified/chimeric superantigens and their use
JP3876002B2 (ja) * 1997-04-14 2007-01-31 ミクロメート・アクチエンゲゼルシャフト 抗ヒト抗原受容体を産生するための斬新な方法およびそれらの使用
JP4776843B2 (ja) 1999-10-01 2011-09-21 イムノゲン インコーポレーティッド 免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法
JP2004537976A (ja) * 2001-03-15 2004-12-24 インターナショナル バイオイムン システムズ，インコーポレーテッド 膵癌のモノクローナル抗体治療
DE10116552A1 (de) * 2001-04-03 2002-10-10 Abc Armbruster Biochemicals Verfahren zur Bestimmung der wirksamen Parathormon-Aktivität in einer Probe
EP1539239A4 (en) * 2002-07-02 2005-09-14 Smithkline Beecham Corp NEW STABLE FORMULATION
US7390898B2 (en) 2002-08-02 2008-06-24 Immunogen Inc. Cytotoxic agents containing novel potent taxanes and their therapeutic use
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
EP1651162B1 (en) 2003-05-20 2015-10-21 ImmunoGen, Inc. Improved cytotoxic agents comprising new maytansinoids
US7811572B2 (en) 2005-08-24 2010-10-12 Immunogen, Inc. Process for preparing purified drug conjugates
AU2006213662B2 (en) 2005-02-11 2010-08-05 Immunogen, Inc. Process for preparing stable drug conjugates
US20110166319A1 (en) * 2005-02-11 2011-07-07 Immunogen, Inc. Process for preparing purified drug conjugates
DK2594591T3 (en) * 2005-08-11 2018-07-30 Matossian Rogers Arpi TCR-V-BETA RELATED PEPTIDES FOR TREATMENT AND DIAGNOSIS OF AUTOIMMUNE DISEASE
AU2012241141B2 (en) * 2005-08-11 2015-08-20 Arpi Matossian-Rogers TCR-V-beta related peptides for treatment and diagnosis of autoimmune disease
MX337991B (es) 2008-08-05 2016-03-30 Toray Industries Metodo para detectar cancer.
JP5784592B2 (ja) 2009-06-03 2015-09-24 イミュノジェン・インコーポレーテッド 抱合方法
EA033468B1 (ru) 2011-03-29 2019-10-31 Immunogen Inc Способы получения конъюгата "антитело-майтансиноид"
WO2012135517A2 (en) 2011-03-29 2012-10-04 Immunogen, Inc. Preparation of maytansinoid antibody conjugates by a one-step process
EP2904089A4 (en) 2012-10-04 2016-05-25 Immunogen Inc USE OF A PVDF MEMBRANE FOR PURIFYING CELL BINDING AGENT-CYTOTOXIC AGENT CONJUGATES
WO2015076425A1 (ja) * 2013-11-25 2015-05-28 リンク・ジェノミクス株式会社 新規モノクローナル抗体
CA2966932A1 (en) 2014-11-19 2016-05-26 Immunogen, Inc. Process for preparing cell-binding agent-cytotoxic agent conjugates
EP3411409B1 (en) 2016-01-10 2025-10-08 Neotx Therapeutics Ltd. Anti pd-1/anti-pd-l1 antibodies for enhancing the potency of superantigen mediated cancer immunotherapy
TW201731532A (zh) 2016-02-05 2017-09-16 伊繆諾金公司 用於製備細胞結合劑-細胞毒性劑結合物之有效方法
CN107167590B (zh) * 2017-04-14 2019-03-08 江苏福隆生物技术有限公司 糖类抗原242的板式化学发光法检测试剂盒及制备方法
WO2019035034A1 (en) * 2017-08-16 2019-02-21 The Broad Institute, Inc. NEURONAL DOSAGE METHOD INVOLVING CALCINEURIN
AU2020275142A1 (en) 2019-05-15 2021-12-16 Neotx Therapeutics Ltd. Cancer treatment
JP2023517011A (ja) 2020-03-05 2023-04-21 ネオティーエックス セラピューティクス リミテッド 免疫細胞を用いて癌を治療するための方法および組成物
EP4732850A1 (en) 2024-10-25 2026-04-29 Antelope Therapeutics SAS Antibody-drug conjugates and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752569A (en) * 1984-06-21 1988-06-21 The Regents Of The University Of California Sialylated Lewisx epitope, antibodies and diagnosis
US4904596A (en) * 1985-08-07 1990-02-27 Fred Hutchinson Cancer Research Center Hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside
SE8902043L (sv) * 1988-11-10 1990-05-11 Pharmacia Ab Foerfarande foer karakterisering av makromolekyler
CA2087163A1 (en) * 1990-07-20 1992-01-21 Hubert Agback Heterobifunctional reagents and conjugates with oxaalkylene units for amphiphilic bridge structures
AU656906B2 (en) * 1990-07-20 1995-02-23 Active Biotech Ab Target specific antibody-superantigen conjugates and their preparation

Also Published As

Publication number Publication date
DE69226990T2 (de) 1999-03-25
KR100246681B1 (ko) 2000-04-01
CA2073124A1 (en) 1993-01-04
NO934777L (no) 1994-02-11
WO1993001303A1 (en) 1993-01-21
ATE171193T1 (de) 1998-10-15
IL102390A (en) 1996-01-19
EP0521842A3 (enExample) 1994-01-26
IL102390A0 (en) 1993-01-14
EP0521842B1 (en) 1998-09-16
CA2073124C (en) 2007-06-19
NO934777D0 (no) 1993-12-22
EP0521842A2 (en) 1993-01-07
NO315472B1 (no) 2003-09-08
JP3194020B2 (ja) 2001-07-30
HU9400011D0 (en) 1994-05-30
FI109207B (fi) 2002-06-14
ES2124250T3 (es) 1999-02-01
HU211512A9 (en) 1995-11-28
NZ243435A (en) 1994-10-26
EE03031B1 (et) 1997-08-15
HUT71193A (en) 1995-11-28
HU218084B (hu) 2000-05-28
AU658198B2 (en) 1995-04-06
FI935970A0 (fi) 1993-12-31
DK0521842T3 (da) 1999-06-14
DE69226990D1 (de) 1998-10-22
US5552293A (en) 1996-09-03
JPH05276987A (ja) 1993-10-26
IE80841B1 (en) 1999-03-24
IE922188A1 (en) 1993-01-13
WO1993001302A1 (en) 1993-01-21
AU1942592A (en) 1993-01-07
FI935970L (fi) 1993-12-31
AU2292092A (en) 1993-02-11

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