SE9102074D0 - Tomour antigen specific antibody - Google Patents

Tomour antigen specific antibody

Info

Publication number
SE9102074D0
SE9102074D0 SE9102074A SE9102074A SE9102074D0 SE 9102074 D0 SE9102074 D0 SE 9102074D0 SE 9102074 A SE9102074 A SE 9102074A SE 9102074 A SE9102074 A SE 9102074A SE 9102074 D0 SE9102074 D0 SE 9102074D0
Authority
SE
Sweden
Prior art keywords
tomour
antibody
specific antibody
antigen specific
antigen
Prior art date
Application number
SE9102074A
Other languages
English (en)
Swedish (sv)
Inventor
L G Lindholm
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE9102074A priority Critical patent/SE9102074D0/xx
Publication of SE9102074D0 publication Critical patent/SE9102074D0/xx
Priority to IL10239092A priority patent/IL102390A/en
Priority to PCT/SE1992/000495 priority patent/WO1993001302A1/en
Priority to DK92850166T priority patent/DK0521842T3/da
Priority to JP17584892A priority patent/JP3194020B2/ja
Priority to AU19425/92A priority patent/AU658198B2/en
Priority to ES92850166T priority patent/ES2124250T3/es
Priority to NZ243435A priority patent/NZ243435A/en
Priority to DE69226990T priority patent/DE69226990T2/de
Priority to KR1019930704117A priority patent/KR100246681B1/ko
Priority to CA002073124A priority patent/CA2073124C/en
Priority to HU9400011A priority patent/HU218084B/hu
Priority to IE922188A priority patent/IE80841B1/en
Priority to AT92850166T priority patent/ATE171193T1/de
Priority to EP92850166A priority patent/EP0521842B1/en
Priority to PCT/SE1992/000502 priority patent/WO1993001303A1/en
Priority to AU22920/92A priority patent/AU2292092A/en
Priority to NO19934777A priority patent/NO315472B1/no
Priority to FI935970A priority patent/FI109207B/fi
Priority to EE9400328A priority patent/EE03031B1/xx
Priority to US08/438,123 priority patent/US5552293A/en
Priority to HU95P/P00289P priority patent/HU211512A9/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1063—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from stomach or intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1057—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from liver or pancreas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SE9102074A 1991-07-03 1991-07-03 Tomour antigen specific antibody SE9102074D0 (sv)

Priority Applications (22)

Application Number Priority Date Filing Date Title
SE9102074A SE9102074D0 (sv) 1991-07-03 1991-07-03 Tomour antigen specific antibody
IL10239092A IL102390A (en) 1991-07-03 1992-07-02 Tumour antigen specific monoclonal antibody its use and cell line producing the antibody and pharmaceutical compositions containing said antibody
PCT/SE1992/000495 WO1993001302A1 (en) 1991-07-03 1992-07-02 Tumor, carbohydrate antigen specific monoclonal antibody and cell line
AU22920/92A AU2292092A (en) 1991-07-03 1992-07-03 Tumor, carbohydrate antigen specific monoclonal antibody and cell line
CA002073124A CA2073124C (en) 1991-07-03 1992-07-03 Tumor antigen specific antibody
IE922188A IE80841B1 (en) 1991-07-03 1992-07-03 Tumor antigen specific antibody
AU19425/92A AU658198B2 (en) 1991-07-03 1992-07-03 Tumour antigen specific antibody, its use and cell in line producing the antibody
ES92850166T ES2124250T3 (es) 1991-07-03 1992-07-03 Anticuerpo especifico para un antigeno tumoral.
NZ243435A NZ243435A (en) 1991-07-03 1992-07-03 Monoclonal antibody specific for a tumour antigen, its use and the cell line responsible for its production
DE69226990T DE69226990T2 (de) 1991-07-03 1992-07-03 Tumorantigen-spezifischer Antikörper
KR1019930704117A KR100246681B1 (ko) 1991-07-03 1992-07-03 종양, 탄수화물 항원에 특이한 모노클로날 항체 및 세포계
DK92850166T DK0521842T3 (da) 1991-07-03 1992-07-03 Tumorantigenspecifikt antistof
HU9400011A HU218084B (hu) 1991-07-03 1992-07-03 Daganatokra specifikus monoklonális antitest és sejtvonal, valamint ezeket tartalmazó gyógyászati készítmények
JP17584892A JP3194020B2 (ja) 1991-07-03 1992-07-03 腫瘍抗原特異的抗体、それを含む医薬組成物およびその抗体を産生する細胞系
AT92850166T ATE171193T1 (de) 1991-07-03 1992-07-03 Tumorantigen-spezifischer antikörper
EP92850166A EP0521842B1 (en) 1991-07-03 1992-07-03 Tumor antigen specific antibody
PCT/SE1992/000502 WO1993001303A1 (en) 1991-07-03 1992-07-03 Tumor, carbohydrate antigen specific monoclonal antibody and cell line
NO19934777A NO315472B1 (no) 1991-07-03 1993-12-22 Tumor, karbohydratantigen spesifikt monoklonalt antistoff og cellelinje, farmasöytisk sammensetning og fremgangsmåte for invitro diagnostikk
FI935970A FI109207B (fi) 1991-07-03 1993-12-31 Tuumori/hiilihydraattiantigeenispesifinen monoklonaalinen vasta-aine ja solulinja
EE9400328A EE03031B1 (et) 1991-07-03 1994-11-16 Kasvaja süsivesik-antigeeni spetsiifiline monokloonne antikeha, meetod in vitro diagnostikaks ja farmatseutilised kompositsioonid
US08/438,123 US5552293A (en) 1991-07-03 1995-05-08 Tumor antigen specific antibody
HU95P/P00289P HU211512A9 (en) 1991-07-03 1995-06-20 Tumor antigen specific antibody and cell line, and pharmaceutical composition comprising them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9102074A SE9102074D0 (sv) 1991-07-03 1991-07-03 Tomour antigen specific antibody

Publications (1)

Publication Number Publication Date
SE9102074D0 true SE9102074D0 (sv) 1991-07-03

Family

ID=20383243

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9102074A SE9102074D0 (sv) 1991-07-03 1991-07-03 Tomour antigen specific antibody

Country Status (19)

Country Link
US (1) US5552293A (enExample)
EP (1) EP0521842B1 (enExample)
JP (1) JP3194020B2 (enExample)
KR (1) KR100246681B1 (enExample)
AT (1) ATE171193T1 (enExample)
AU (2) AU658198B2 (enExample)
CA (1) CA2073124C (enExample)
DE (1) DE69226990T2 (enExample)
DK (1) DK0521842T3 (enExample)
EE (1) EE03031B1 (enExample)
ES (1) ES2124250T3 (enExample)
FI (1) FI109207B (enExample)
HU (2) HU218084B (enExample)
IE (1) IE80841B1 (enExample)
IL (1) IL102390A (enExample)
NO (1) NO315472B1 (enExample)
NZ (1) NZ243435A (enExample)
SE (1) SE9102074D0 (enExample)
WO (2) WO1993001302A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9402430L (sv) 1994-07-11 1996-01-12 Pharmacia Ab Konjugat mellan modifierat superantigen och en målsökande förening samt användning av konjugaten
SE9601245D0 (sv) 1996-03-29 1996-03-29 Pharmacia Ab Chimeric superantigens and their use
TW517061B (en) 1996-03-29 2003-01-11 Pharmacia & Amp Upjohn Ab Modified/chimeric superantigens and their use
TR199902553T2 (xx) * 1997-04-14 2000-03-21 Micromet Gesellschaft F�R Biomedizinische Forschung Mbh �nsan v�cuduna kar�� antijen resept�rlerinin �retimi i�in yeni metod ve kullan�mlar�.
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
JP2004537976A (ja) * 2001-03-15 2004-12-24 インターナショナル バイオイムン システムズ，インコーポレーテッド 膵癌のモノクローナル抗体治療
DE10116552A1 (de) * 2001-04-03 2002-10-10 Abc Armbruster Biochemicals Verfahren zur Bestimmung der wirksamen Parathormon-Aktivität in einer Probe
NZ537610A (en) * 2002-07-02 2006-07-28 Smithkline Beecham Corp Stable formulations of the C242 antibody
US7390898B2 (en) 2002-08-02 2008-06-24 Immunogen Inc. Cytotoxic agents containing novel potent taxanes and their therapeutic use
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
KR101145506B1 (ko) 2003-05-20 2012-05-15 이뮤노젠 아이엔씨 새로운 메이탠시노이드를 포함하는 개선된 세포독성체
US20110166319A1 (en) * 2005-02-11 2011-07-07 Immunogen, Inc. Process for preparing purified drug conjugates
JP5165387B2 (ja) 2005-02-11 2013-03-21 イムノゲン インコーポレーティッド 安定な薬物複合体を調製するための方法
AU2012241141B2 (en) * 2005-08-11 2015-08-20 Arpi Matossian-Rogers TCR-V-beta related peptides for treatment and diagnosis of autoimmune disease
GB2429013C (en) * 2005-08-11 2012-11-28 Arpi Matossian-Rogers Peptides for treatment and diagnosis of autoimmunedisease
EP3539572A1 (en) 2005-08-24 2019-09-18 ImmunoGen, Inc. Process for preparing maytansinoid antibody conjugates
US11137401B2 (en) 2008-08-05 2021-10-05 Toray Industries, Inc. Method for detecting cancer using CAPRIN-1 as a marker
EP2437790B1 (en) 2009-06-03 2019-02-20 Immunogen, Inc. Conjugation methods
WO2012135517A2 (en) 2011-03-29 2012-10-04 Immunogen, Inc. Preparation of maytansinoid antibody conjugates by a one-step process
TR201902180T4 (tr) 2011-03-29 2019-03-21 Immunogen Inc Tek adimli bi̇r i̇şlem i̇le maytansi̇noi̇d anti̇kor konjugatlarinin hazirlanmasi
RU2661083C2 (ru) 2012-10-04 2018-07-11 Иммуноджен, Инк. Использование пвдф-мембраны для очистки конъюгатов клеточно-связывающий агент - цитотоксический агент
WO2015076425A1 (ja) * 2013-11-25 2015-05-28 リンク・ジェノミクス株式会社 新規モノクローナル抗体
US10413615B2 (en) 2014-11-19 2019-09-17 Immunogen, Inc. Process for preparing cell-binding agent-cytotoxic agent conjugates
EA201891601A1 (ru) 2016-01-10 2019-03-29 Неоткс Терапьютикс Лтд. Способы и композиции, усиливающие эффективность опосредованной суперантигеном иммунотерапии злокачественных опухолей
JP2019510741A (ja) 2016-02-05 2019-04-18 イミュノジェン・インコーポレーテッド 細胞結合剤・細胞毒性剤コンジュゲートを調製するための効率的なプロセス
CN107167590B (zh) * 2017-04-14 2019-03-08 江苏福隆生物技术有限公司 糖类抗原242的板式化学发光法检测试剂盒及制备方法
US20200256880A1 (en) * 2017-08-16 2020-08-13 The Broad Institute, Inc. Neuronal Assay Method Involving Calcineurin
EA202193121A1 (ru) 2019-05-15 2022-02-21 Неоткс Терапьютикс Лтд. Лечение рака
AU2021357520A1 (en) 2020-03-05 2022-09-29 Neotx Therapeutics Ltd. Methods and compositions for treating cancer with immune cells
EP4732850A1 (en) 2024-10-25 2026-04-29 Antelope Therapeutics SAS Antibody-drug conjugates and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752569A (en) * 1984-06-21 1988-06-21 The Regents Of The University Of California Sialylated Lewisx epitope, antibodies and diagnosis
US4904596A (en) * 1985-08-07 1990-02-27 Fred Hutchinson Cancer Research Center Hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside
SE8902043L (sv) * 1988-11-10 1990-05-11 Pharmacia Ab Foerfarande foer karakterisering av makromolekyler
CA2087163A1 (en) * 1990-07-20 1992-01-21 Hubert Agback Heterobifunctional reagents and conjugates with oxaalkylene units for amphiphilic bridge structures
ES2094231T3 (es) * 1990-07-20 1997-01-16 Pharmacia & Upjohn Ab Conjugados de anticuerpos superantigenos especificos de una diana y su preparacion.

Also Published As

Publication number Publication date
IL102390A (en) 1996-01-19
EE03031B1 (et) 1997-08-15
WO1993001303A1 (en) 1993-01-21
DK0521842T3 (da) 1999-06-14
KR100246681B1 (ko) 2000-04-01
HU211512A9 (en) 1995-11-28
NZ243435A (en) 1994-10-26
HU218084B (hu) 2000-05-28
FI935970A0 (fi) 1993-12-31
HUT71193A (en) 1995-11-28
FI935970L (fi) 1993-12-31
DE69226990T2 (de) 1999-03-25
ATE171193T1 (de) 1998-10-15
US5552293A (en) 1996-09-03
EP0521842A3 (enExample) 1994-01-26
DE69226990D1 (de) 1998-10-22
CA2073124A1 (en) 1993-01-04
AU658198B2 (en) 1995-04-06
EP0521842A2 (en) 1993-01-07
FI109207B (fi) 2002-06-14
IE922188A1 (en) 1993-01-13
ES2124250T3 (es) 1999-02-01
AU2292092A (en) 1993-02-11
CA2073124C (en) 2007-06-19
IE80841B1 (en) 1999-03-24
JP3194020B2 (ja) 2001-07-30
AU1942592A (en) 1993-01-07
NO934777D0 (no) 1993-12-22
IL102390A0 (en) 1993-01-14
WO1993001302A1 (en) 1993-01-21
EP0521842B1 (en) 1998-09-16
JPH05276987A (ja) 1993-10-26
HU9400011D0 (en) 1994-05-30
NO934777L (no) 1994-02-11
NO315472B1 (no) 2003-09-08

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