SE9003057D0 - New process - Google Patents

New process

Info

Publication number
SE9003057D0
SE9003057D0 SE9003057A SE9003057A SE9003057D0 SE 9003057 D0 SE9003057 D0 SE 9003057D0 SE 9003057 A SE9003057 A SE 9003057A SE 9003057 A SE9003057 A SE 9003057A SE 9003057 D0 SE9003057 D0 SE 9003057D0
Authority
SE
Sweden
Prior art keywords
new process
directed
present
formoterol
related compounds
Prior art date
Application number
SE9003057A
Other languages
English (en)
Swedish (sv)
Inventor
J Trofast
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9003057A priority Critical patent/SE9003057D0/xx
Publication of SE9003057D0 publication Critical patent/SE9003057D0/xx
Priority to RU9193005269A priority patent/RU2079486C1/ru
Priority to CZ93442A priority patent/CZ284256B6/cs
Priority to AT91917624T priority patent/ATE134990T1/de
Priority to IS3756A priority patent/IS1684B/is
Priority to KR1019930700901A priority patent/KR0179639B1/ko
Priority to SG1996004479A priority patent/SG43150A1/en
Priority to PCT/SE1991/000643 priority patent/WO1992005147A1/en
Priority to JP3516242A priority patent/JP2801401B2/ja
Priority to DK91917624.8T priority patent/DK0550612T3/da
Priority to AU86520/91A priority patent/AU652386B2/en
Priority to DE69117768T priority patent/DE69117768T2/de
Priority to EP91917624A priority patent/EP0550612B1/en
Priority to CA002091343A priority patent/CA2091343C/en
Priority to SK22793A priority patent/SK22793A3/sk
Priority to PL91298237A priority patent/PL166434B1/pl
Priority to PT99051A priority patent/PT99051B/pt
Priority to HU9300867A priority patent/HU214054B/hu
Priority to ES91917624T priority patent/ES2084831T3/es
Priority to IE337391A priority patent/IE74387B1/en
Priority to NO931058A priority patent/NO301709B1/no
Priority to BG97576A priority patent/BG61605B1/bg
Priority to FI931333A priority patent/FI111714B/fi
Priority to LVP-93-1025A priority patent/LV10770B/en
Priority to LTIP1715A priority patent/LT3813B/lt
Priority to US08/309,167 priority patent/US5434304A/en
Priority to EE9400425A priority patent/EE02979B1/xx
Priority to GR960401514T priority patent/GR3020134T3/el
Priority to HK52297A priority patent/HK52297A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/42Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/43Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/14Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
SE9003057A 1990-09-26 1990-09-26 New process SE9003057D0 (sv)

Priority Applications (29)

Application Number Priority Date Filing Date Title
SE9003057A SE9003057D0 (sv) 1990-09-26 1990-09-26 New process
ES91917624T ES2084831T3 (es) 1990-09-26 1991-09-25 Nuevo procedimiento para preparar formoterol y compuestos relacionados.
EP91917624A EP0550612B1 (en) 1990-09-26 1991-09-25 New process for preparing formoterol and related compounds
SK22793A SK22793A3 (en) 1990-09-26 1991-09-25 New process for preparimg formoterol and related compounds
AT91917624T ATE134990T1 (de) 1990-09-26 1991-09-25 Neues verfahren zur darstellung von formoterol und vewandten verbindungen
IS3756A IS1684B (is) 1990-09-26 1991-09-25 Ný aðferð við framleiðslu formóteról og skyldra efnablandna6
KR1019930700901A KR0179639B1 (ko) 1990-09-26 1991-09-25 포르모테롤 및 관련 화합물의 신규 제조 방법
SG1996004479A SG43150A1 (en) 1990-09-26 1991-09-25 New process for preparing formoterol and related compounds
PCT/SE1991/000643 WO1992005147A1 (en) 1990-09-26 1991-09-25 New process for preparing formoterol and related compounds
JP3516242A JP2801401B2 (ja) 1990-09-26 1991-09-25 新規な製法
DK91917624.8T DK0550612T3 (da) 1990-09-26 1991-09-25 Ny fremgangsmåde til fremstilling af formoterol ogbeslægtede forbindelser
AU86520/91A AU652386B2 (en) 1990-09-26 1991-09-25 New process for preparing formoterol and related compounds
DE69117768T DE69117768T2 (de) 1990-09-26 1991-09-25 Neues verfahren zur darstellung von formoterol und vewandten verbindungen
RU9193005269A RU2079486C1 (ru) 1990-09-26 1991-09-25 Способ получения формотерола или его производных
CA002091343A CA2091343C (en) 1990-09-26 1991-09-25 Process for preparing formoterol and related compounds
CZ93442A CZ284256B6 (cs) 1990-09-26 1991-09-25 Nový způsob výroby formoterolu a příbuzných sloučenin
PL91298237A PL166434B1 (pl) 1990-09-26 1991-09-25 S posób wytwarzania alkoholu 3-formamido-4-hydroksy-a-{N-[1 -metylo-2- (p-metoksyfenylo)-etylo]-aminometylo}benzylowego PL PL PL
PT99051A PT99051B (pt) 1990-09-26 1991-09-25 Processo para a preparacao de formoterol e de compostos com ele relacionados e seus derivados
HU9300867A HU214054B (en) 1990-09-26 1991-09-25 Novel process for preparing formoterol and it's n-alkyl-derivatives
IE337391A IE74387B1 (en) 1990-09-26 1991-09-26 New process for preparing formoterol and related compounds
NO931058A NO301709B1 (no) 1990-09-26 1993-03-23 Fremgangsmåte for fremstilling av formoterol og beslektede forbindelser
BG97576A BG61605B1 (bg) 1990-09-26 1993-03-24 Метод за получаване на формотерол и съединения от същатагрупа
FI931333A FI111714B (fi) 1990-09-26 1993-03-25 Uusi menetelmä formoterolin ja lähisukuisten yhdisteiden valmistamiseksi
LVP-93-1025A LV10770B (en) 1990-09-26 1993-08-10 Process for preparation of formoterol
LTIP1715A LT3813B (en) 1990-09-26 1993-12-30 Process for preparing 3-formamido-4-hydroxy-alpha£n£1-methyl-2(p-methoxyphenyl)ethylaminomethyl|benzyl alkohol fumarate (formoterol) and related compounds and derivatives thereof
US08/309,167 US5434304A (en) 1990-09-26 1994-09-20 Process for preparing formoterol and related compounds
EE9400425A EE02979B1 (et) 1990-09-26 1994-11-23 Formoterool ja tema ühendid ning nende valmistamise meetod
GR960401514T GR3020134T3 (en) 1990-09-26 1996-05-31 New process for preparing formoterol and related compounds
HK52297A HK52297A (en) 1990-09-26 1997-04-24 New process for preparing formoterol and related compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9003057A SE9003057D0 (sv) 1990-09-26 1990-09-26 New process

Publications (1)

Publication Number Publication Date
SE9003057D0 true SE9003057D0 (sv) 1990-09-26

Family

ID=20380456

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9003057A SE9003057D0 (sv) 1990-09-26 1990-09-26 New process

Country Status (28)

Country Link
EP (1) EP0550612B1 (cs)
JP (1) JP2801401B2 (cs)
KR (1) KR0179639B1 (cs)
AT (1) ATE134990T1 (cs)
AU (1) AU652386B2 (cs)
BG (1) BG61605B1 (cs)
CA (1) CA2091343C (cs)
CZ (1) CZ284256B6 (cs)
DE (1) DE69117768T2 (cs)
DK (1) DK0550612T3 (cs)
EE (1) EE02979B1 (cs)
ES (1) ES2084831T3 (cs)
FI (1) FI111714B (cs)
GR (1) GR3020134T3 (cs)
HK (1) HK52297A (cs)
HU (1) HU214054B (cs)
IE (1) IE74387B1 (cs)
IS (1) IS1684B (cs)
LT (1) LT3813B (cs)
LV (1) LV10770B (cs)
NO (1) NO301709B1 (cs)
PL (1) PL166434B1 (cs)
PT (1) PT99051B (cs)
RU (1) RU2079486C1 (cs)
SE (1) SE9003057D0 (cs)
SG (1) SG43150A1 (cs)
SK (1) SK22793A3 (cs)
WO (1) WO1992005147A1 (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6299863B1 (en) 1992-04-03 2001-10-09 Sepracor Inc. Aerosol formulations containing micronized optically pure (R,R) formoterol for bronchodilating therapy
US6866839B2 (en) 1991-04-05 2005-03-15 Sepracor Inc. Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
US5795564A (en) * 1991-04-05 1998-08-18 Sepracor, Inc. Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
US5629200A (en) * 1993-11-18 1997-05-13 Daicel Chemical Industries, Ltd. Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation
SE9404080L (sv) * 1993-12-28 1995-06-29 Ciba Geigy Ag Förfarande för framställning av en optiskt ren enantiomer av formoterol
CA2271004C (en) * 1996-11-11 2007-05-01 Sepracor Inc. Process for the preparation of optically pure isomers of formoterol
US6040344A (en) 1996-11-11 2000-03-21 Sepracor Inc. Formoterol process
US6303145B2 (en) 1999-05-10 2001-10-16 Sepracor Inc. (S,R) formoterol methods and compositions
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
DE10290563D2 (de) * 2001-02-22 2004-04-29 Universitaetsklinikum Charite Mittel zur Hemmung von Tumorzellen
US6472563B1 (en) 2001-11-09 2002-10-29 Sepracor Inc. Formoterol tartrate process and polymorph
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
TW200738634A (en) 2005-08-02 2007-10-16 Astrazeneca Ab New salt
WO2008035380A2 (en) * 2006-09-19 2008-03-27 Natco Pharma Limited An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts
TW200825084A (en) 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
AU2008320590A1 (en) * 2007-10-29 2009-05-07 Generics [Uk] Limited Novel chromatography methods
JP4837800B2 (ja) 2008-05-13 2011-12-14 アストラゼネカ・アクチエボラーグ ムスカリンm3受容体アンタゴニストとしてのキヌクリジン誘導体
CN101921200B (zh) * 2009-06-16 2014-01-15 上海医药工业研究院 一种n-苄基-1-(4-甲氧基苯基)-2-丙胺的制备方法
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
CN115368250B (zh) * 2022-09-02 2024-07-26 博诺康源(北京)药业科技有限公司 拆分福莫特罗手性中间体的方法
CN117682969A (zh) * 2023-07-31 2024-03-12 浙江理工大学 一种福莫特罗中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2366625C2 (cs) * 1972-02-05 1988-06-09 Yamanouchi Pharmaceutical Co., Ltd., Tokio/Tokyo, Jp
GB1468156A (en) * 1973-07-19 1977-03-23 Ici Ltd Phenylethylamine derivatives
ES2005492A6 (es) 1987-12-23 1989-03-01 Lasa Lab Procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2((2- (4-metoxifenil)-1metiletil)amino)etil)fenil)foramida (i).

Also Published As

Publication number Publication date
CZ44293A3 (en) 1994-01-19
HU214054B (en) 1997-12-29
FI931333A0 (fi) 1993-03-25
EE02979B1 (et) 1997-04-15
PL166434B1 (pl) 1995-05-31
FI111714B (fi) 2003-09-15
SK22793A3 (en) 1993-07-07
LT3813B (en) 1996-03-25
NO931058L (no) 1993-03-23
LTIP1715A (en) 1995-07-25
EP0550612B1 (en) 1996-03-06
NO931058D0 (no) 1993-03-23
IE74387B1 (en) 1997-07-30
ES2084831T3 (es) 1996-05-16
GR3020134T3 (en) 1996-08-31
NO301709B1 (no) 1997-12-01
EP0550612A1 (en) 1993-07-14
AU8652091A (en) 1992-04-15
HUT65912A (en) 1994-07-28
DE69117768T2 (de) 1996-08-29
JP2801401B2 (ja) 1998-09-21
WO1992005147A1 (en) 1992-04-02
IS3756A7 (is) 1992-03-27
IS1684B (is) 1998-02-24
CA2091343A1 (en) 1992-03-27
LV10770B (en) 1996-04-20
HK52297A (en) 1997-05-02
BG61605B1 (bg) 1998-01-30
JPH06501262A (ja) 1994-02-10
KR0179639B1 (ko) 1999-05-15
FI931333L (fi) 1993-04-22
LV10770A (lv) 1995-08-20
DK0550612T3 (da) 1996-07-22
DE69117768D1 (de) 1996-04-11
IE913373A1 (en) 1992-04-08
CA2091343C (en) 2002-07-09
HU9300867D0 (en) 1993-06-28
PT99051A (pt) 1992-08-31
RU2079486C1 (ru) 1997-05-20
ATE134990T1 (de) 1996-03-15
SG43150A1 (en) 1997-10-17
AU652386B2 (en) 1994-08-25
BG97576A (bg) 1994-03-31
CZ284256B6 (cs) 1998-10-14
PT99051B (pt) 1999-02-26

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