ATE134990T1 - Neues verfahren zur darstellung von formoterol und vewandten verbindungen - Google Patents
Neues verfahren zur darstellung von formoterol und vewandten verbindungenInfo
- Publication number
- ATE134990T1 ATE134990T1 AT91917624T AT91917624T ATE134990T1 AT E134990 T1 ATE134990 T1 AT E134990T1 AT 91917624 T AT91917624 T AT 91917624T AT 91917624 T AT91917624 T AT 91917624T AT E134990 T1 ATE134990 T1 AT E134990T1
- Authority
- AT
- Austria
- Prior art keywords
- related compounds
- formoterol
- new method
- preparing
- preparing formoterol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9003057A SE9003057D0 (sv) | 1990-09-26 | 1990-09-26 | New process |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE134990T1 true ATE134990T1 (de) | 1996-03-15 |
Family
ID=20380456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91917624T ATE134990T1 (de) | 1990-09-26 | 1991-09-25 | Neues verfahren zur darstellung von formoterol und vewandten verbindungen |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP0550612B1 (de) |
JP (1) | JP2801401B2 (de) |
KR (1) | KR0179639B1 (de) |
AT (1) | ATE134990T1 (de) |
AU (1) | AU652386B2 (de) |
BG (1) | BG61605B1 (de) |
CA (1) | CA2091343C (de) |
CZ (1) | CZ284256B6 (de) |
DE (1) | DE69117768T2 (de) |
DK (1) | DK0550612T3 (de) |
EE (1) | EE02979B1 (de) |
ES (1) | ES2084831T3 (de) |
FI (1) | FI111714B (de) |
GR (1) | GR3020134T3 (de) |
HK (1) | HK52297A (de) |
HU (1) | HU214054B (de) |
IE (1) | IE74387B1 (de) |
IS (1) | IS1684B (de) |
LT (1) | LT3813B (de) |
LV (1) | LV10770B (de) |
NO (1) | NO301709B1 (de) |
PL (1) | PL166434B1 (de) |
PT (1) | PT99051B (de) |
RU (1) | RU2079486C1 (de) |
SE (1) | SE9003057D0 (de) |
SG (1) | SG43150A1 (de) |
SK (1) | SK22793A3 (de) |
WO (1) | WO1992005147A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6299863B1 (en) | 1992-04-03 | 2001-10-09 | Sepracor Inc. | Aerosol formulations containing micronized optically pure (R,R) formoterol for bronchodilating therapy |
US6866839B2 (en) | 1991-04-05 | 2005-03-15 | Sepracor Inc. | Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol |
US5795564A (en) * | 1991-04-05 | 1998-08-18 | Sepracor, Inc. | Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol |
US5629200A (en) | 1993-11-18 | 1997-05-13 | Daicel Chemical Industries, Ltd. | Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation |
SE9404080L (sv) * | 1993-12-28 | 1995-06-29 | Ciba Geigy Ag | Förfarande för framställning av en optiskt ren enantiomer av formoterol |
US6040344A (en) * | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
ES2178015T3 (es) * | 1996-11-11 | 2002-12-16 | Sepracor Inc | Procedimiento de preparacion de isomeros de formoterol opticamente puros. |
US6303145B2 (en) | 1999-05-10 | 2001-10-16 | Sepracor Inc. | (S,R) formoterol methods and compositions |
AR028948A1 (es) | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
WO2002066021A2 (de) * | 2001-02-22 | 2002-08-29 | Universitätsklinikum Charite Medizinische Fakultät Der Humboldt-Universität Zu Berlin | Inhibitoren der protein kinase d und der protein kinase 2 als mittel zur hemmung von tumorzellen und zur stimulierung der angiogehese |
US6472563B1 (en) | 2001-11-09 | 2002-10-29 | Sepracor Inc. | Formoterol tartrate process and polymorph |
TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
TW200738634A (en) | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
WO2008035380A2 (en) * | 2006-09-19 | 2008-03-27 | Natco Pharma Limited | An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts |
TW200825084A (en) | 2006-11-14 | 2008-06-16 | Astrazeneca Ab | New compounds 521 |
AU2008320590A1 (en) * | 2007-10-29 | 2009-05-07 | Generics [Uk] Limited | Novel chromatography methods |
BRPI0822693A2 (pt) | 2008-05-13 | 2015-07-07 | Astrazeneca Ab | Derivados de quinuclidina como antagonistas do receptor muscarínico m3 |
CN101921200B (zh) * | 2009-06-16 | 2014-01-15 | 上海医药工业研究院 | 一种n-苄基-1-(4-甲氧基苯基)-2-丙胺的制备方法 |
WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
CN115368250A (zh) * | 2022-09-02 | 2022-11-22 | 博诺康源(北京)药业科技有限公司 | 拆分福莫特罗手性中间体的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2305092A1 (de) | 1972-02-05 | 1973-08-16 | Yamanouchi Pharma Co Ltd | Alpha-aminomethylbenzylalkoholderivate |
GB1468156A (en) * | 1973-07-19 | 1977-03-23 | Ici Ltd | Phenylethylamine derivatives |
JPS643121A (en) | 1987-06-25 | 1989-01-06 | Mitsubishi Kasei Corp | Remedy for endometriosis |
ES2005492A6 (es) | 1987-12-23 | 1989-03-01 | Lasa Lab | Procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2((2- (4-metoxifenil)-1metiletil)amino)etil)fenil)foramida (i). |
-
1990
- 1990-09-26 SE SE9003057A patent/SE9003057D0/xx unknown
-
1991
- 1991-09-25 CZ CZ93442A patent/CZ284256B6/cs not_active IP Right Cessation
- 1991-09-25 SK SK22793A patent/SK22793A3/sk unknown
- 1991-09-25 JP JP3516242A patent/JP2801401B2/ja not_active Expired - Lifetime
- 1991-09-25 PT PT99051A patent/PT99051B/pt not_active IP Right Cessation
- 1991-09-25 PL PL91298237A patent/PL166434B1/pl unknown
- 1991-09-25 EP EP91917624A patent/EP0550612B1/de not_active Expired - Lifetime
- 1991-09-25 DE DE69117768T patent/DE69117768T2/de not_active Expired - Lifetime
- 1991-09-25 IS IS3756A patent/IS1684B/is unknown
- 1991-09-25 DK DK91917624.8T patent/DK0550612T3/da active
- 1991-09-25 AT AT91917624T patent/ATE134990T1/de not_active IP Right Cessation
- 1991-09-25 AU AU86520/91A patent/AU652386B2/en not_active Expired
- 1991-09-25 ES ES91917624T patent/ES2084831T3/es not_active Expired - Lifetime
- 1991-09-25 SG SG1996004479A patent/SG43150A1/en unknown
- 1991-09-25 WO PCT/SE1991/000643 patent/WO1992005147A1/en active IP Right Grant
- 1991-09-25 CA CA002091343A patent/CA2091343C/en not_active Expired - Lifetime
- 1991-09-25 RU RU9193005269A patent/RU2079486C1/ru active
- 1991-09-25 KR KR1019930700901A patent/KR0179639B1/ko not_active IP Right Cessation
- 1991-09-25 HU HU9300867A patent/HU214054B/hu unknown
- 1991-09-26 IE IE337391A patent/IE74387B1/en not_active IP Right Cessation
-
1993
- 1993-03-23 NO NO931058A patent/NO301709B1/no not_active IP Right Cessation
- 1993-03-24 BG BG97576A patent/BG61605B1/bg unknown
- 1993-03-25 FI FI931333A patent/FI111714B/fi not_active IP Right Cessation
- 1993-08-10 LV LVP-93-1025A patent/LV10770B/en unknown
- 1993-12-30 LT LTIP1715A patent/LT3813B/lt not_active IP Right Cessation
-
1994
- 1994-11-23 EE EE9400425A patent/EE02979B1/xx unknown
-
1996
- 1996-05-31 GR GR960401514T patent/GR3020134T3/el unknown
-
1997
- 1997-04-24 HK HK52297A patent/HK52297A/xx not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EELA | Cancelled due to lapse of time |