DE69303497D1 - Pyrrolidinderivate und Verfahren zur Herstellung solcher Verbindungen - Google Patents

Pyrrolidinderivate und Verfahren zur Herstellung solcher Verbindungen

Info

Publication number
DE69303497D1
DE69303497D1 DE69303497T DE69303497T DE69303497D1 DE 69303497 D1 DE69303497 D1 DE 69303497D1 DE 69303497 T DE69303497 T DE 69303497T DE 69303497 T DE69303497 T DE 69303497T DE 69303497 D1 DE69303497 D1 DE 69303497D1
Authority
DE
Germany
Prior art keywords
compounds
preparation
pyrrolidine derivatives
pyrrolidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69303497T
Other languages
English (en)
Other versions
DE69303497T2 (de
Inventor
Makoto Sunagawa
Haruki Matsumura
Takashi Bando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharmaceuticals Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Publication of DE69303497D1 publication Critical patent/DE69303497D1/de
Application granted granted Critical
Publication of DE69303497T2 publication Critical patent/DE69303497T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69303497T 1992-01-10 1993-01-07 Pyrrolidinderivate und Verfahren zur Herstellung solcher Verbindungen Expired - Fee Related DE69303497T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP04022104A JP3091297B2 (ja) 1992-01-10 1992-01-10 ピロリジン誘導体およびその製造方法

Publications (2)

Publication Number Publication Date
DE69303497D1 true DE69303497D1 (de) 1996-08-14
DE69303497T2 DE69303497T2 (de) 1997-01-23

Family

ID=12073586

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69303497T Expired - Fee Related DE69303497T2 (de) 1992-01-10 1993-01-07 Pyrrolidinderivate und Verfahren zur Herstellung solcher Verbindungen

Country Status (7)

Country Link
US (1) US5322952A (de)
EP (1) EP0551993B1 (de)
JP (1) JP3091297B2 (de)
KR (1) KR930016425A (de)
CA (1) CA2086649A1 (de)
DE (1) DE69303497T2 (de)
ES (1) ES2089709T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648501A (en) * 1995-08-04 1997-07-15 Merck & Co., Inc. Process for synthesizing carbapenem side chain intermediates
ATE197456T1 (de) * 1995-08-04 2000-11-11 Merck & Co Inc Verfahren zur herstellung von zwischenprodukten von carbapenem-seitenketten
US5721368A (en) * 1996-07-22 1998-02-24 Merck & Co. Inc. Process for synthesizing carbapenem side chain intermediates
AU731586B2 (en) * 1997-07-09 2001-04-05 Merck Sharp & Dohme Corp. Process for synthesizing carbapenem side chain intermediates
US6063931A (en) * 1997-07-09 2000-05-16 Merck & Co., Inc. Process for synthesizing carbapenem side chain intermediates
US6060607A (en) * 1998-06-29 2000-05-09 Merck & Co., Inc. Process for synthesizing carbapenem side chain intermediates
JP4068452B2 (ja) 2000-07-19 2008-03-26 エフ．ホフマン−ラ ロシュ アーゲー エンドセリン変換酵素阻害剤としてのピロリジン誘導体
ATE315568T1 (de) 2000-11-20 2006-02-15 Sankyo Co Verfahren zur herstellung antibakterieller verbindungen vom carbapenem-typ
JP2004035507A (ja) * 2002-07-05 2004-02-05 Nippon Soda Co Ltd ピロール誘導体及びその製造方法
CA2530680A1 (en) * 2003-04-04 2004-10-14 Alpharma Aps Process for the preparation of steroidal carbothioic acid derivatives and intermediates
CN101367812B (zh) * 2007-06-28 2011-04-27 山东轩竹医药科技有限公司 被巯基吡咯烷甲酰胺基环戊烯酸取代的培南衍生物
US8236792B2 (en) * 2008-05-23 2012-08-07 Janssen Pharmaceutica Nv Substituted pyrrolidine amides as modulators of the histamine H3 receptor
WO2010073706A1 (ja) * 2008-12-25 2010-07-01 株式会社カネカ カルバペネム側鎖中間体の改良された製造方法
CN102002069A (zh) * 2010-11-12 2011-04-06 上海巴迪生物医药科技有限公司 一种合成培南类侧链的双环中间体的制备方法及其应用
CN102134249B (zh) * 2010-12-30 2015-11-25 天津市敬业精细化工有限公司 一种手性5-保护-2-硫杂-5-氮杂双环[2.2.1]庚-3-酮的制备方法
CN102351861A (zh) * 2011-08-16 2012-02-15 湖南欧亚生物有限公司 一种厄他培南的工业化制备方法
CN104130262B (zh) * 2014-08-12 2017-06-09 湖南凯米尔生物科技有限公司 一种厄他培南、厄他培南侧链及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991076A (en) * 1974-06-07 1976-11-09 American Hoechst Corporation Aminoalkylthiopyranopyrroles
US4321383A (en) * 1980-11-24 1982-03-23 E. R. Squibb & Sons, Inc. Heterobicyclo intermediates
FR2537974A1 (fr) * 1982-12-16 1984-06-22 Adir Nouveaux derives de thieno (2,3-b) pyrrole, leur procede de preparation et les compositions pharmaceutiques les renfermant
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JP3005045B2 (ja) * 1990-02-14 2000-01-31 住友製薬株式会社 新規なβ―ラクタム化合物及びその製造法
CA2036163C (en) * 1990-02-14 2001-06-19 Makoto Sunagawa Novel beta-lactam compounds and their production

Also Published As

Publication number Publication date
KR930016425A (ko) 1993-08-26
EP0551993A1 (de) 1993-07-21
ES2089709T3 (es) 1996-10-01
JP3091297B2 (ja) 2000-09-25
CA2086649A1 (en) 1993-07-11
JPH05186476A (ja) 1993-07-27
US5322952A (en) 1994-06-21
DE69303497T2 (de) 1997-01-23
EP0551993B1 (de) 1996-07-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee