RU93005269A - Способ получения формотерола и родственных соединений - Google Patents
Способ получения формотерола и родственных соединенийInfo
- Publication number
- RU93005269A RU93005269A RU93005269/04A RU93005269A RU93005269A RU 93005269 A RU93005269 A RU 93005269A RU 93005269/04 A RU93005269/04 A RU 93005269/04A RU 93005269 A RU93005269 A RU 93005269A RU 93005269 A RU93005269 A RU 93005269A
- Authority
- RU
- Russia
- Prior art keywords
- related compounds
- formotherol
- obtaining
- formoterol
- present
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims 3
- BPZSYCZIITTYBL-YJYMSZOUSA-N Formoterol Chemical compound C1=CC(OC)=CC=C1C[C@@H](C)NC[C@H](O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-YJYMSZOUSA-N 0.000 claims 2
- 229960002848 formoterol Drugs 0.000 claims 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-L fumarate(2-) Chemical class [O-]C(=O)\C=C\C([O-])=O VZCYOOQTPOCHFL-OWOJBTEDSA-L 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
Claims (1)
- Настоящее изобретение относится к способу получения формотерола и его родственных соединений и производных, а также к их фармакологически и фармацевтически приемлемым фумаратным солям и/или сольватам. Настоящее изобретение направлено также на некоторые формотерольные родственные соединения per se.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9003057-8 | 1990-09-26 | ||
| SE9003057A SE9003057D0 (sv) | 1990-09-26 | 1990-09-26 | New process |
| PCT/SE1991/000643 WO1992005147A1 (en) | 1990-09-26 | 1991-09-25 | New process for preparing formoterol and related compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93005269A true RU93005269A (ru) | 1996-04-27 |
| RU2079486C1 RU2079486C1 (ru) | 1997-05-20 |
Family
ID=20380456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU9193005269A RU2079486C1 (ru) | 1990-09-26 | 1991-09-25 | Способ получения формотерола или его производных |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP0550612B1 (ru) |
| JP (1) | JP2801401B2 (ru) |
| KR (1) | KR0179639B1 (ru) |
| AT (1) | ATE134990T1 (ru) |
| AU (1) | AU652386B2 (ru) |
| BG (1) | BG61605B1 (ru) |
| CA (1) | CA2091343C (ru) |
| CZ (1) | CZ284256B6 (ru) |
| DE (1) | DE69117768T2 (ru) |
| DK (1) | DK0550612T3 (ru) |
| EE (1) | EE02979B1 (ru) |
| ES (1) | ES2084831T3 (ru) |
| FI (1) | FI111714B (ru) |
| GR (1) | GR3020134T3 (ru) |
| HK (1) | HK52297A (ru) |
| HU (1) | HU214054B (ru) |
| IE (1) | IE74387B1 (ru) |
| IS (1) | IS1684B (ru) |
| LT (1) | LT3813B (ru) |
| LV (1) | LV10770B (ru) |
| NO (1) | NO301709B1 (ru) |
| PL (1) | PL166434B1 (ru) |
| PT (1) | PT99051B (ru) |
| RU (1) | RU2079486C1 (ru) |
| SE (1) | SE9003057D0 (ru) |
| SG (1) | SG43150A1 (ru) |
| SK (1) | SK22793A3 (ru) |
| WO (1) | WO1992005147A1 (ru) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6299863B1 (en) | 1992-04-03 | 2001-10-09 | Sepracor Inc. | Aerosol formulations containing micronized optically pure (R,R) formoterol for bronchodilating therapy |
| US6866839B2 (en) | 1991-04-05 | 2005-03-15 | Sepracor Inc. | Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol |
| US5795564A (en) * | 1991-04-05 | 1998-08-18 | Sepracor, Inc. | Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol |
| US5629200A (en) * | 1993-11-18 | 1997-05-13 | Daicel Chemical Industries, Ltd. | Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation |
| SE9404080L (sv) * | 1993-12-28 | 1995-06-29 | Ciba Geigy Ag | Förfarande för framställning av en optiskt ren enantiomer av formoterol |
| US6040344A (en) | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
| CA2271004C (en) * | 1996-11-11 | 2007-05-01 | Sepracor Inc. | Process for the preparation of optically pure isomers of formoterol |
| US6303145B2 (en) | 1999-05-10 | 2001-10-16 | Sepracor Inc. | (S,R) formoterol methods and compositions |
| AR028948A1 (es) | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
| DE10207881A1 (de) * | 2001-02-22 | 2003-02-13 | Universitaetsklinikum Charite | Zielkomplex als Mittel zur Hemmung von Tumorzellen und zur Stimulierung der Angiogenese |
| US6472563B1 (en) | 2001-11-09 | 2002-10-29 | Sepracor Inc. | Formoterol tartrate process and polymorph |
| TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| TW200738634A (en) | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
| WO2008035380A2 (en) * | 2006-09-19 | 2008-03-27 | Natco Pharma Limited | An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts |
| TW200825084A (en) | 2006-11-14 | 2008-06-16 | Astrazeneca Ab | New compounds 521 |
| US20100288022A1 (en) * | 2007-10-29 | 2010-11-18 | Mylan India Private Limited | Novel chromatography methods |
| EP2300464A1 (en) | 2008-05-13 | 2011-03-30 | AstraZeneca AB | Quinuclidine derivatives as muscarinic m3 receptor antagonists |
| CN101921200B (zh) * | 2009-06-16 | 2014-01-15 | 上海医药工业研究院 | 一种n-苄基-1-(4-甲氧基苯基)-2-丙胺的制备方法 |
| WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
| CN115368250A (zh) * | 2022-09-02 | 2022-11-22 | 博诺康源(北京)药业科技有限公司 | 拆分福莫特罗手性中间体的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2305092A1 (de) | 1972-02-05 | 1973-08-16 | Yamanouchi Pharma Co Ltd | Alpha-aminomethylbenzylalkoholderivate |
| GB1468156A (en) * | 1973-07-19 | 1977-03-23 | Ici Ltd | Phenylethylamine derivatives |
| ES2005492A6 (es) | 1987-12-23 | 1989-03-01 | Lasa Lab | Procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2((2- (4-metoxifenil)-1metiletil)amino)etil)fenil)foramida (i). |
-
1990
- 1990-09-26 SE SE9003057A patent/SE9003057D0/xx unknown
-
1991
- 1991-09-25 CZ CZ93442A patent/CZ284256B6/cs not_active IP Right Cessation
- 1991-09-25 WO PCT/SE1991/000643 patent/WO1992005147A1/en active IP Right Grant
- 1991-09-25 PL PL91298237A patent/PL166434B1/pl unknown
- 1991-09-25 KR KR1019930700901A patent/KR0179639B1/ko not_active IP Right Cessation
- 1991-09-25 PT PT99051A patent/PT99051B/pt not_active IP Right Cessation
- 1991-09-25 ES ES91917624T patent/ES2084831T3/es not_active Expired - Lifetime
- 1991-09-25 DK DK91917624.8T patent/DK0550612T3/da active
- 1991-09-25 CA CA002091343A patent/CA2091343C/en not_active Expired - Lifetime
- 1991-09-25 JP JP3516242A patent/JP2801401B2/ja not_active Expired - Lifetime
- 1991-09-25 SG SG1996004479A patent/SG43150A1/en unknown
- 1991-09-25 EP EP91917624A patent/EP0550612B1/en not_active Expired - Lifetime
- 1991-09-25 IS IS3756A patent/IS1684B/is unknown
- 1991-09-25 AT AT91917624T patent/ATE134990T1/de not_active IP Right Cessation
- 1991-09-25 SK SK22793A patent/SK22793A3/sk unknown
- 1991-09-25 AU AU86520/91A patent/AU652386B2/en not_active Expired
- 1991-09-25 HU HU9300867A patent/HU214054B/hu unknown
- 1991-09-25 RU RU9193005269A patent/RU2079486C1/ru active
- 1991-09-25 DE DE69117768T patent/DE69117768T2/de not_active Expired - Lifetime
- 1991-09-26 IE IE337391A patent/IE74387B1/en not_active IP Right Cessation
-
1993
- 1993-03-23 NO NO931058A patent/NO301709B1/no not_active IP Right Cessation
- 1993-03-24 BG BG97576A patent/BG61605B1/bg unknown
- 1993-03-25 FI FI931333A patent/FI111714B/fi not_active IP Right Cessation
- 1993-08-10 LV LVP-93-1025A patent/LV10770B/en unknown
- 1993-12-30 LT LTIP1715A patent/LT3813B/lt not_active IP Right Cessation
-
1994
- 1994-11-23 EE EE9400425A patent/EE02979B1/xx unknown
-
1996
- 1996-05-31 GR GR960401514T patent/GR3020134T3/el unknown
-
1997
- 1997-04-24 HK HK52297A patent/HK52297A/xx not_active IP Right Cessation
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