SE8904298D0 - New compounds - Google Patents
New compoundsInfo
- Publication number
- SE8904298D0 SE8904298D0 SE8904298A SE8904298A SE8904298D0 SE 8904298 D0 SE8904298 D0 SE 8904298D0 SE 8904298 A SE8904298 A SE 8904298A SE 8904298 A SE8904298 A SE 8904298A SE 8904298 D0 SE8904298 D0 SE 8904298D0
- Authority
- SE
- Sweden
- Prior art keywords
- new compounds
- compounds
- analgetica
- anaesthetica
- local
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cosmetics (AREA)
Priority Applications (42)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8904298A SE8904298D0 (sv) | 1989-12-21 | 1989-12-21 | New compounds |
NZ236293A NZ236293A (en) | 1989-12-21 | 1990-11-30 | 1-(alkyl or alkoxyalkyl)-4-phenyl piperidine-4-carboxylic acid amide derivatives; preparatory processes and pharmaceutical compositions |
ZA909903A ZA909903B (en) | 1989-12-21 | 1990-12-10 | New compounds |
IL9663690A IL96636A (en) | 1989-12-21 | 1990-12-11 | History of piperidine Process for preparation and pharmaceutical preparations containing them |
YU234690A YU48086B (sh) | 1989-12-21 | 1990-12-12 | Supstituisani 4-fenil-4-piperidinkarboksamid i postupak za njihovo dobijanje |
DZ900223A DZ1468A1 (fr) | 1989-12-21 | 1990-12-12 | Composés nouveaux. |
SI9012346A SI9012346B (sl) | 1989-12-21 | 1990-12-12 | Substituirani 4-fenil-4-piperidinkarboksamidi z lokalno-anestezijskim in analgetskim učinkom kot tudi postopki za njihovo pripravo |
DK91901571.9T DK0506778T3 (da) | 1989-12-21 | 1990-12-17 | Substituerede 4-phenyl-4-piperidincarboxamider med både lokal anæstetisk og analgetisk virkning samt fremgangsmåder til deres fremstilling |
AT91901571T ATE138650T1 (de) | 1989-12-21 | 1990-12-17 | Substituierte 4-phenyl-4-piperidincarboxamide mit sowohl lokalanästhetischer als auch schmerzlindernder wirkung sowie verfahren zur herstellung |
KR1019920701484A KR0179382B1 (ko) | 1989-12-21 | 1990-12-17 | 국부 마취 및 진통 효과를 갖는 치환 4-페닐-4-피페리딘카르복스아미드 및 그의 제조 방법 |
HU9202044A HU213110B (en) | 1989-12-21 | 1990-12-17 | Process for producing 4-phenyl-piperidine-4-carboxamide derivatives and pharmaceutical preparatives containing them as active agents |
IS3659A IS1664B (is) | 1989-12-21 | 1990-12-17 | Ný aðferð við að framleiða útskipt 4-fenýl-4-píperídínkarboxamíð sem hefur bæði staðbundin deyfandiog kvalastillandi áhrif |
IE453490A IE74855B1 (en) | 1989-12-21 | 1990-12-17 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
SG1996004491A SG46413A1 (en) | 1989-12-21 | 1990-12-17 | Substituted 4-phenyl-4-piperdinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
RO92-0832A RO112864B1 (ro) | 1989-12-21 | 1990-12-17 | Derivati substituiti ai 4-fenil-4-piperidincarboxamidelor cu efect analgezic si anestezic local, procedeu de obtinere a acestora si compozitie farmaceutica care ii contine |
DE69027221T DE69027221T2 (de) | 1989-12-21 | 1990-12-17 | Substituierte 4-phenyl-4-piperidincarboxamide mit sowohl lokalanästhetischer als auch schmerzlindernder wirkung sowie verfahren zur herstellung |
ES91901571T ES2087280T3 (es) | 1989-12-21 | 1990-12-17 | 4-fenil-4-piperidina-carboxamidas sustituidas con efecto tanto anestesico local como analgesico, asi como procedimientos para su preparacion. |
UA5052485A UA26403A (uk) | 1989-12-21 | 1990-12-17 | Похідhі n-заміщеhого 4-феhіл-4-піперидиhкарбоксаміду та їх фармацевтичhо прийhятhі солі, що проявляють аhестезувальhу та аhальгезувальhу дію, спосіб їх одержаhhя та фармацевтичhа композиція |
PCT/SE1990/000818 WO1991009845A1 (en) | 1989-12-21 | 1990-12-17 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
CA002069608A CA2069608C (en) | 1989-12-21 | 1990-12-17 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
JP3501896A JP2656152B2 (ja) | 1989-12-21 | 1990-12-17 | 局所麻酔作用および鎮痛作用の両方を有する置換された4―フェニル―4―ピペリジンカルボキサミドならびにその製法 |
EP91901571A EP0506778B1 (en) | 1989-12-21 | 1990-12-17 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
AU69783/91A AU647068B2 (en) | 1989-12-21 | 1990-12-17 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
EG74690A EG19361A (en) | 1989-12-21 | 1990-12-20 | A process for the preparation of piperidine compound having local anaesthetica and analgetic |
PT96303A PT96303B (pt) | 1989-12-21 | 1990-12-20 | Processo para a preparacao de novos derivados do acido piperidinocarboxilico com accao anestesica local e analgesica e de composicoes farmaceuticas que os contem |
PL90288409A PL163591B1 (pl) | 1989-12-21 | 1990-12-21 | Sposób wytwarzania nowych pochodnych 4-fenylo-4-piperydynokarboksyamldu PL PL PL PL PL |
CN90106009A CN1037841C (zh) | 1989-12-21 | 1990-12-21 | 具有局部麻醉和止痛作用的取代4-苯基-4-呱啶甲酰胺的制备方法 |
CS906581A CZ278035B6 (en) | 1989-12-21 | 1990-12-21 | Substituted piperidinecarboxamides, process of their preparation, pharmaceutical compositions in which they are comprised |
US07/633,246 US5227389A (en) | 1989-12-21 | 1990-12-21 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
SK6581-90A SK278283B6 (en) | 1989-12-21 | 1990-12-21 | Substituted piperidinecarboxamides, method of their manufacture, pharmaceutical drugs containing them and their application |
SA91110209A SA91110209B1 (ar) | 1989-12-21 | 1991-01-09 | مركبات 4-فينيل-4- بيبريدين كاربوكساميد مستبدلة Substituted -4- phenyl -4-piperidincarboxamide لها مفعول مخدر موضعي ومسكن وكذلك طرق لتحضيرها |
NO922380A NO178858C (no) | 1989-12-21 | 1992-06-17 | Analogifremgangsmåte for fremstilling av substituerte 4-fenyl-4-piperidinkarboksamider med både lokal anestetisk og analgetisk effekt |
FI922806A FI100881B (fi) | 1989-12-21 | 1992-06-17 | Menetelmä farmakologisesti aktiivisten, substituoitujen 4-fenyyli-4-pi peridiinikarboksamidien valmistamiseksi |
BG96513A BG60912B1 (bg) | 1989-12-21 | 1992-06-19 | Заместени 4-фенил-4-пиперидинкарбоксамиди с локален обезболя- ващ и болкоуспокояващ ефект и метод за получаването им |
SU925052485A RU2039043C1 (ru) | 1989-12-21 | 1992-06-19 | Производное n-замещенного 1-гексил-4-фенил-4-пиперидинкарбоксамида или его фармацевтически приемлемая соль и способ его получения |
HRP-2346/90A HRP920591B1 (en) | 1989-12-21 | 1992-09-29 | New compounds |
US08/090,416 US5360805A (en) | 1989-12-21 | 1993-07-12 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
LVP-93-1042A LV10949B (en) | 1989-12-21 | 1993-08-27 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
LTIP1731A LT4005B (en) | 1989-12-21 | 1993-12-30 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
LV960262A LV5766B4 (lv) | 1989-12-21 | 1996-07-17 | Aizvietoti 4-fenil-4-piperidinkarboksamidi ar lokalu anestezejosu un analgetisku daribu ka ari to iegusanas metodes |
HK22997A HK22997A (en) | 1989-12-21 | 1997-02-27 | Substituted 4-phenyl-4-piperidine-carboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
BR1100379-0A BR1100379A (pt) | 1989-12-21 | 1997-04-30 | Composto, uso de um composto, preparação farmacêutica e processo para preparação de um composto |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8904298A SE8904298D0 (sv) | 1989-12-21 | 1989-12-21 | New compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE8904298D0 true SE8904298D0 (sv) | 1989-12-21 |
Family
ID=20377821
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8904298A SE8904298D0 (sv) | 1989-12-21 | 1989-12-21 | New compounds |
Country Status (40)
Country | Link |
---|---|
US (2) | US5227389A (cs) |
EP (1) | EP0506778B1 (cs) |
JP (1) | JP2656152B2 (cs) |
KR (1) | KR0179382B1 (cs) |
CN (1) | CN1037841C (cs) |
AT (1) | ATE138650T1 (cs) |
AU (1) | AU647068B2 (cs) |
BG (1) | BG60912B1 (cs) |
BR (1) | BR1100379A (cs) |
CA (1) | CA2069608C (cs) |
CZ (1) | CZ278035B6 (cs) |
DE (1) | DE69027221T2 (cs) |
DK (1) | DK0506778T3 (cs) |
DZ (1) | DZ1468A1 (cs) |
EG (1) | EG19361A (cs) |
ES (1) | ES2087280T3 (cs) |
FI (1) | FI100881B (cs) |
HK (1) | HK22997A (cs) |
HR (1) | HRP920591B1 (cs) |
HU (1) | HU213110B (cs) |
IE (1) | IE74855B1 (cs) |
IL (1) | IL96636A (cs) |
IS (1) | IS1664B (cs) |
LT (1) | LT4005B (cs) |
LV (2) | LV10949B (cs) |
NO (1) | NO178858C (cs) |
NZ (1) | NZ236293A (cs) |
PL (1) | PL163591B1 (cs) |
PT (1) | PT96303B (cs) |
RO (1) | RO112864B1 (cs) |
RU (1) | RU2039043C1 (cs) |
SA (1) | SA91110209B1 (cs) |
SE (1) | SE8904298D0 (cs) |
SG (1) | SG46413A1 (cs) |
SI (1) | SI9012346B (cs) |
SK (1) | SK278283B6 (cs) |
UA (1) | UA26403A (cs) |
WO (1) | WO1991009845A1 (cs) |
YU (1) | YU48086B (cs) |
ZA (1) | ZA909903B (cs) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3916092B2 (ja) * | 1993-09-17 | 2007-05-16 | 杏林製薬株式会社 | イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬 |
SE9400447D0 (sv) * | 1994-02-11 | 1994-02-11 | Astra Ab | New compounds |
SE9404438D0 (sv) * | 1994-12-21 | 1994-12-21 | Astra Ab | New process |
US5931809A (en) | 1995-07-14 | 1999-08-03 | Depotech Corporation | Epidural administration of therapeutic compounds with sustained rate of release |
US7799337B2 (en) | 1997-07-21 | 2010-09-21 | Levin Bruce H | Method for directed intranasal administration of a composition |
US20020102291A1 (en) * | 1997-12-15 | 2002-08-01 | Noven Pharmaceuticals, Inc. | Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
PE20021081A1 (es) * | 2001-04-12 | 2002-12-18 | Pharmacopeia Drug Discovery | Aril y biaril piperidinas con actividad moduladora mch |
CN1744899A (zh) * | 2002-12-13 | 2006-03-08 | 史密丝克莱恩比彻姆公司 | 作为ccr5拮抗剂的哌啶衍生物 |
AR063275A1 (es) * | 2006-10-12 | 2009-01-14 | Epix Delaware Inc | Compuestos de carboxamida, una composicion farmaceutica que los comprende y su uso en la preparacion de un medicamento para el tratamiento de enfermedades mediadas por la activacion de ccr2. |
AU2008335135A1 (en) | 2007-12-11 | 2009-06-18 | Cytopathfinder, Inc. | Carboxamide compounds and their use as chemokine receptor agonists |
US8473062B2 (en) | 2008-05-01 | 2013-06-25 | Autonomic Technologies, Inc. | Method and device for the treatment of headache |
US8412336B2 (en) | 2008-12-29 | 2013-04-02 | Autonomic Technologies, Inc. | Integrated delivery and visualization tool for a neuromodulation system |
US9320908B2 (en) | 2009-01-15 | 2016-04-26 | Autonomic Technologies, Inc. | Approval per use implanted neurostimulator |
US8494641B2 (en) | 2009-04-22 | 2013-07-23 | Autonomic Technologies, Inc. | Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism |
EP3914246A1 (en) | 2019-01-22 | 2021-12-01 | ICM (Institut du Cerveau et de la Moelle Épinière) | Local anesthetic for the treatment of neurological symptoms resulting from brain dysfunctions |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE96980C1 (cs) | ||||
US2486796A (en) * | 1943-06-25 | 1949-11-01 | Ciba Pharm Prod Inc | Esters of 1-alkyl-4-hydroxyphenylpiperidyl-4-ketones |
US3334106A (en) * | 1964-10-20 | 1967-08-01 | Aldrich Chem Co Inc | N(aryl)n(hydrocarbyl)-omega-(4-phenyl-4-piperidinocarbonylheteroamine) alkanoamide |
US3539580A (en) * | 1967-06-26 | 1970-11-10 | Janssen Pharm | 4-aryl-4-aminoalkoxy-piperidines |
CH498836A (de) * | 1968-12-20 | 1970-11-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Piperidinderivaten |
US3737538A (en) * | 1968-12-30 | 1973-06-05 | Ciba Geigy Corp | Antitussive compositions and method with isonipecotic acid derivatives |
FR2156470A2 (en) * | 1971-10-21 | 1973-06-01 | Synthelabo | 1-(3,3-diphenyl-1-propyl)-4-aryl-piperidines - as analgesics spasmolytic and anti-tussive agents |
ZA899436B (en) * | 1988-12-12 | 1990-08-29 | Ciba Geigy | Piperidine derivatives |
US5100903A (en) * | 1989-05-12 | 1992-03-31 | Anaquest, Inc. | N-aryl-n-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds |
-
1989
- 1989-12-21 SE SE8904298A patent/SE8904298D0/xx unknown
-
1990
- 1990-11-30 NZ NZ236293A patent/NZ236293A/xx unknown
- 1990-12-10 ZA ZA909903A patent/ZA909903B/xx unknown
- 1990-12-11 IL IL9663690A patent/IL96636A/en not_active IP Right Cessation
- 1990-12-12 SI SI9012346A patent/SI9012346B/sl not_active IP Right Cessation
- 1990-12-12 YU YU234690A patent/YU48086B/sh unknown
- 1990-12-12 DZ DZ900223A patent/DZ1468A1/xx active
- 1990-12-17 EP EP91901571A patent/EP0506778B1/en not_active Expired - Lifetime
- 1990-12-17 IE IE453490A patent/IE74855B1/en not_active IP Right Cessation
- 1990-12-17 DE DE69027221T patent/DE69027221T2/de not_active Expired - Fee Related
- 1990-12-17 AU AU69783/91A patent/AU647068B2/en not_active Ceased
- 1990-12-17 RO RO92-0832A patent/RO112864B1/ro unknown
- 1990-12-17 HU HU9202044A patent/HU213110B/hu unknown
- 1990-12-17 DK DK91901571.9T patent/DK0506778T3/da active
- 1990-12-17 JP JP3501896A patent/JP2656152B2/ja not_active Expired - Fee Related
- 1990-12-17 WO PCT/SE1990/000818 patent/WO1991009845A1/en active IP Right Grant
- 1990-12-17 KR KR1019920701484A patent/KR0179382B1/ko not_active IP Right Cessation
- 1990-12-17 UA UA5052485A patent/UA26403A/uk unknown
- 1990-12-17 CA CA002069608A patent/CA2069608C/en not_active Expired - Fee Related
- 1990-12-17 SG SG1996004491A patent/SG46413A1/en unknown
- 1990-12-17 IS IS3659A patent/IS1664B/is unknown
- 1990-12-17 AT AT91901571T patent/ATE138650T1/de not_active IP Right Cessation
- 1990-12-17 ES ES91901571T patent/ES2087280T3/es not_active Expired - Lifetime
- 1990-12-20 EG EG74690A patent/EG19361A/xx active
- 1990-12-20 PT PT96303A patent/PT96303B/pt active IP Right Grant
- 1990-12-21 CN CN90106009A patent/CN1037841C/zh not_active Expired - Fee Related
- 1990-12-21 PL PL90288409A patent/PL163591B1/pl not_active IP Right Cessation
- 1990-12-21 SK SK6581-90A patent/SK278283B6/sk unknown
- 1990-12-21 US US07/633,246 patent/US5227389A/en not_active Expired - Lifetime
- 1990-12-21 CZ CS906581A patent/CZ278035B6/cs not_active IP Right Cessation
-
1991
- 1991-01-09 SA SA91110209A patent/SA91110209B1/ar unknown
-
1992
- 1992-06-17 FI FI922806A patent/FI100881B/fi not_active IP Right Cessation
- 1992-06-17 NO NO922380A patent/NO178858C/no unknown
- 1992-06-19 BG BG96513A patent/BG60912B1/bg unknown
- 1992-06-19 RU SU925052485A patent/RU2039043C1/ru not_active IP Right Cessation
- 1992-09-29 HR HRP-2346/90A patent/HRP920591B1/xx not_active IP Right Cessation
-
1993
- 1993-07-12 US US08/090,416 patent/US5360805A/en not_active Expired - Lifetime
- 1993-08-27 LV LVP-93-1042A patent/LV10949B/lv unknown
- 1993-12-30 LT LTIP1731A patent/LT4005B/lt not_active IP Right Cessation
-
1996
- 1996-07-17 LV LV960262A patent/LV5766B4/xx unknown
-
1997
- 1997-02-27 HK HK22997A patent/HK22997A/xx not_active IP Right Cessation
- 1997-04-30 BR BR1100379-0A patent/BR1100379A/pt active IP Right Grant
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