SE8705150D0 - Novel antiarrhythmic agents - Google Patents

Novel antiarrhythmic agents

Info

Publication number
SE8705150D0
SE8705150D0 SE8705150A SE8705150A SE8705150D0 SE 8705150 D0 SE8705150 D0 SE 8705150D0 SE 8705150 A SE8705150 A SE 8705150A SE 8705150 A SE8705150 A SE 8705150A SE 8705150 D0 SE8705150 D0 SE 8705150D0
Authority
SE
Sweden
Prior art keywords
antiarrhythmic agents
chem
compounds
novel antiarrhythmic
novel
Prior art date
Application number
SE8705150A
Other languages
English (en)
Swedish (sv)
Inventor
K O S Almgren
B G D Duker
G C Strandlund
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Priority to SE8705150A priority Critical patent/SE8705150D0/xx
Publication of SE8705150D0 publication Critical patent/SE8705150D0/xx
Priority to ZA889424A priority patent/ZA889424B/xx
Priority to NZ227381A priority patent/NZ227381A/en
Priority to NZ24080588A priority patent/NZ240805A/en
Priority to ES88850427T priority patent/ES2043891T3/es
Priority to DE8888850427T priority patent/DE3875600T2/de
Priority to AT88850427T priority patent/ATE81848T1/de
Priority to EP88850427A priority patent/EP0322389B1/en
Priority to JP1500469A priority patent/JPH02502726A/ja
Priority to ES88850428T priority patent/ES2045189T3/es
Priority to JP50046888A priority patent/JPH0637458B2/ja
Priority to PCT/SE1988/000692 priority patent/WO1989005795A1/en
Priority to HU89359A priority patent/HU205895B/hu
Priority to AU28244/89A priority patent/AU2824489A/en
Priority to AU28244/89A priority patent/AU625774B2/en
Priority to HU89361A priority patent/HUT54346A/hu
Priority to EP88850428A priority patent/EP0322390B1/en
Priority to AT88850428T priority patent/ATE82257T1/de
Priority to DE8888850428T priority patent/DE3875934T2/de
Priority to PCT/SE1988/000691 priority patent/WO1989005794A1/en
Priority to AU28241/89A priority patent/AU625872B2/en
Priority to HU913679A priority patent/HU913679D0/hu
Priority to IL10374188A priority patent/IL103741A/en
Priority to IS3425A priority patent/IS1558B/is
Priority to IL8874988A priority patent/IL88749A/en
Priority to PH37960A priority patent/PH26828A/en
Priority to PH37959A priority patent/PH25526A/en
Priority to IE883860A priority patent/IE883860L/xx
Priority to MX014310A priority patent/MX174084B/es
Priority to PT89311A priority patent/PT89311B/pt
Priority to PT89312A priority patent/PT89312B/pt
Priority to EG653/88A priority patent/EG18681A/xx
Priority to US07/289,630 priority patent/US5034411A/en
Priority to AR88312835A priority patent/AR247729A1/es
Priority to PCT/SE1988/000697 priority patent/WO1989005806A1/en
Priority to MYPI88001510A priority patent/MY103945A/en
Priority to AU29103/89A priority patent/AU2910389A/en
Priority to IE883859A priority patent/IE883859L/xx
Priority to CN88108941A priority patent/CN1033804A/zh
Priority to PL1988276698A priority patent/PL157747B1/pl
Priority to YU234088A priority patent/YU47580B/sh
Priority to PL1988287936A priority patent/PL159551B1/pl
Priority to DD88324296A priority patent/DD277274A5/de
Priority to ZA894441A priority patent/ZA894441B/xx
Priority to DD89329730A priority patent/DD295353A5/de
Priority to CN89104335A priority patent/CN1048214A/zh
Priority to DK404889A priority patent/DK404889A/da
Priority to DK404789A priority patent/DK404789A/da
Priority to NO893376A priority patent/NO171784C/no
Priority to KR1019890701579A priority patent/KR900700441A/ko
Priority to NO893375A priority patent/NO171724C/no
Priority to SU894614909A priority patent/RU1836342C/ru
Priority to SU894614813A priority patent/RU2024503C1/ru
Priority to FI893937A priority patent/FI893937A/fi
Priority to FI893936A priority patent/FI92192C/sv
Priority to KR1019890701592A priority patent/KR900700442A/ko
Priority to YU00196/90A priority patent/YU19690A/xx
Priority to US07/643,161 priority patent/US5155133A/en
Priority to SU914895329A priority patent/RU1836343C/ru
Priority to GR920402579T priority patent/GR3006241T3/el
Priority to IL103741A priority patent/IL103741A0/xx
Priority to FI930337A priority patent/FI930337A/fi
Priority to GR930400159T priority patent/GR3006912T3/el
Priority to LV930851A priority patent/LV10250A/xx
Priority to LTIP1687A priority patent/LTIP1687A/xx
Priority to LTIP1688A priority patent/LTIP1688A/xx
Priority to LTIP1720A priority patent/LTIP1720A/xx
Priority to LTIP1752A priority patent/LTIP1752A/xx
Priority to CN94105497A priority patent/CN1097736A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyridine Compounds (AREA)
SE8705150A 1987-12-23 1987-12-23 Novel antiarrhythmic agents SE8705150D0 (sv)

Priority Applications (69)

Application Number Priority Date Filing Date Title
SE8705150A SE8705150D0 (sv) 1987-12-23 1987-12-23 Novel antiarrhythmic agents
ZA889424A ZA889424B (en) 1987-12-23 1988-12-15 Novel antiarrhythmic agents
NZ227381A NZ227381A (en) 1987-12-23 1988-12-19 Thioalkylaminoalkoxybenzonitrile derivatives and pharmaceutical compositions
NZ24080588A NZ240805A (en) 1987-12-23 1988-12-19 Alkylamino-substituted thiol, sulphinyl and sulphonyl derivatives
ES88850427T ES2043891T3 (es) 1987-12-23 1988-12-20 Procedimiento para preparar nuevos agentes antiarritmicos ii.
DE8888850427T DE3875600T2 (de) 1987-12-23 1988-12-20 Antiarrythmische derivate 2.
AT88850427T ATE81848T1 (de) 1987-12-23 1988-12-20 Antiarrythmische derivate 2.
EP88850427A EP0322389B1 (en) 1987-12-23 1988-12-20 Novel antiarrhythmic agents ii
JP1500469A JPH02502726A (ja) 1987-12-23 1988-12-20 新規な抗不整脈剤２
ES88850428T ES2045189T3 (es) 1987-12-23 1988-12-20 Nuevos agentes anti-arritmicos i.
JP50046888A JPH0637458B2 (ja) 1987-12-23 1988-12-20 新規な抗不整脈剤ι
PCT/SE1988/000692 WO1989005795A1 (en) 1987-12-23 1988-12-20 Novel antiarrhythmic agents ii
HU89359A HU205895B (en) 1987-12-23 1988-12-20 Process for producing sulfur-containing cyano-phenol derivatives and pharmaceutical compositions containing them
AU28244/89A AU2824489A (en) 1987-12-23 1988-12-20 Novel antiarrhythmic agents ii
AU28244/89A AU625774B2 (en) 1987-12-23 1988-12-20 Novel antiarrhythmic agents ii
HU89361A HUT54346A (en) 1987-12-23 1988-12-20 Process for producing new, antiarrhythmic, sulfur-containing cyanophenol derivatives and medical compositions comprising same
EP88850428A EP0322390B1 (en) 1987-12-23 1988-12-20 Novel antiarrhythmic agents i
AT88850428T ATE82257T1 (de) 1987-12-23 1988-12-20 Antiarrythmische derivate 1.
DE8888850428T DE3875934T2 (de) 1987-12-23 1988-12-20 Antiarrythmische derivate 1.
PCT/SE1988/000691 WO1989005794A1 (en) 1987-12-23 1988-12-20 Novel antiarrhythmic agents i
AU28241/89A AU625872B2 (en) 1987-12-23 1988-12-20 Novel antiarrhythmic agents i
HU913679A HU913679D0 (en) 1987-12-23 1988-12-20 Process for the production of n-alkyl-n-alkyltio-amines
IL10374188A IL103741A (en) 1987-12-23 1988-12-21 Amino assemblies and their preparation
IS3425A IS1558B (is) 1987-12-23 1988-12-21 Nýtt lyf gegn hjartsláttaróreglu
IL8874988A IL88749A (en) 1987-12-23 1988-12-21 History of P-Cyanophenoxy Alkylamine Containing Sulfur, Process for Their Preparation and Antiarrhythmic Preparations Containing Them
PH37960A PH26828A (en) 1987-12-23 1988-12-21 Benzonitrile derivatives pharmaceutical preparations and use thereof
PH37959A PH25526A (en) 1987-12-23 1988-12-21 Benzonitrile derivatives, pharmaceutical preparations, use thereof
IE883860A IE883860L (en) 1987-12-23 1988-12-22 Novel antiarrhythmic agents ii
MX014310A MX174084B (es) 1987-12-23 1988-12-22 Procedimiento para la preparacion de agentes antiarritmicos producto obtenido y preparacion farmaceutica que lo incluye
PT89311A PT89311B (pt) 1987-12-23 1988-12-22 Processo para a preparacao de novos aminoalcoxi-p-benzonitrilos substituidos utilizaveis como agentes antiarritmicos e de composicoes farmaceuticas que os contem
PT89312A PT89312B (pt) 1987-12-23 1988-12-22 Processo para a preparacao de novos benzonitrilos substituidos na posicao para utilizaveis como agentes antiarritmicos e de composicoes farmaceuticas que os contem
EG653/88A EG18681A (en) 1987-12-23 1988-12-22 Process for preparing novel antiarrhythmic agents
US07/289,630 US5034411A (en) 1987-12-23 1988-12-22 Novel 4-cyanophenyl derivatives with action against cardiac arrhythmia
AR88312835A AR247729A1 (es) 1987-12-23 1988-12-22 Procedimiento para preparar nuevos compuestos antiarritmicos
PCT/SE1988/000697 WO1989005806A1 (en) 1987-12-23 1988-12-22 Novel antiarrhythmic agents iii
MYPI88001510A MY103945A (en) 1987-12-23 1988-12-22 Novel antiarrhythmic agents i
AU29103/89A AU2910389A (en) 1987-12-23 1988-12-22 Novel antiarrhythmic agents iii
IE883859A IE883859L (en) 1987-12-23 1988-12-22 Novel antiarrhythmic agents i
CN88108941A CN1033804A (zh) 1987-12-23 1988-12-23 新的抗心律失常剂及其制备方法
PL1988276698A PL157747B1 (pl) 1987-12-23 1988-12-23 Sposób wytwarzania nowych pochodnych benzonitrylu PL PL PL
YU234088A YU47580B (sh) 1987-12-23 1988-12-23 Postupak za dobijanje novih derivata benzonitrila
PL1988287936A PL159551B1 (pl) 1987-12-23 1988-12-23 Sposób wytwarzania nowych pochodnych benzonitrylu PL PL PL
DD88324296A DD277274A5 (de) 1987-12-23 1988-12-28 Verfahren zur herstellung von alkoxybenzonitrilderivaten
ZA894441A ZA894441B (en) 1987-12-23 1989-06-12 Novel antiarrhymtic agents ii
DD89329730A DD295353A5 (de) 1987-12-23 1989-06-19 Verfahren zur herstellung von benzonitrilderivaten
CN89104335A CN1048214A (zh) 1987-12-23 1989-06-22 新的抗心律失常药ii的制备方法
DK404889A DK404889A (da) 1987-12-23 1989-08-17 Nye antiarrytmiske midler ii
DK404789A DK404789A (da) 1987-12-23 1989-08-17 Nye antiarrytmiske midler i
NO893376A NO171784C (no) 1987-12-23 1989-08-22 Analogifremgangsmaate for fremstilling av nye antiarytmiske midler samt nye forbindelser for bruk ved fremstillingen
KR1019890701579A KR900700441A (ko) 1987-12-23 1989-08-22 신규 항부정맥제 ⅱ
NO893375A NO171724C (no) 1987-12-23 1989-08-22 Analogifremgangsmaate for fremstilling av nye antiarytmiske midler samt nye forbindelser for bruk ved fremstillingen
SU894614909A RU1836342C (ru) 1987-12-23 1989-08-22 Способ получени производных бензонитрила
SU894614813A RU2024503C1 (ru) 1987-12-23 1989-08-22 Производные бензонитрила, или их рацематы, или фармацевтически приемлемые соли, обладающие антиаритмическим действием, и состав для лечения сердечной аритмии
FI893937A FI893937A (fi) 1987-12-23 1989-08-22 Nya antiarytmiska aemnen ii.
FI893936A FI92192C (sv) 1987-12-23 1989-08-22 Förfarande för framställning av terapeutiskt aktiva föreningar samt mellanprodukter
KR1019890701592A KR900700442A (ko) 1987-12-23 1989-08-23 신규 부정맥 치료제 i
YU00196/90A YU19690A (en) 1987-12-23 1990-02-02 Process for obtaining new derivatives of benzonitryl
US07/643,161 US5155133A (en) 1987-12-23 1991-01-18 Antiarrhythmic compounds and pharmaceutical compositions and methods thereof
SU914895329A RU1836343C (ru) 1987-12-23 1991-04-22 Способ получени производных бензонитрила или их фармацевтически приемлемых солей
GR920402579T GR3006241T3 (no) 1987-12-23 1992-11-12
IL103741A IL103741A0 (en) 1987-12-23 1992-11-13 Amino compounds and their preparation
FI930337A FI930337A (fi) 1987-12-23 1993-01-27 N-alkyl-n-(alkyltioalkyl)aminderivat anvaendbara som mellanprodukter
GR930400159T GR3006912T3 (no) 1987-12-23 1993-01-28
LV930851A LV10250A (lv) 1987-12-23 1993-06-30 Jauni antiaritmijas lidzekli panemiens to iegusanai arstniecibas lidzeklis pielietojums
LTIP1687A LTIP1687A (en) 1987-12-23 1993-12-28 Novel antiarrhythmic agents, process for the preparation thereof and pharmaceutical compositions
LTIP1688A LTIP1688A (en) 1987-12-23 1993-12-28 Process for the preparation of antiarrhythmic agents
LTIP1720A LTIP1720A (en) 1987-12-23 1993-12-30 Novel antiarrhythmic agents, process for the preparation and use thereof
LTIP1752A LTIP1752A (en) 1987-12-23 1993-12-31 Benzonitrile derivatives
CN94105497A CN1097736A (zh) 1987-12-23 1994-05-31 新的抗心律失常剂及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8705150A SE8705150D0 (sv) 1987-12-23 1987-12-23 Novel antiarrhythmic agents

Publications (1)

Publication Number Publication Date
SE8705150D0 true SE8705150D0 (sv) 1987-12-23

Family

ID=20370706

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8705150A SE8705150D0 (sv) 1987-12-23 1987-12-23 Novel antiarrhythmic agents

Country Status (33)

Country Link
US (2) US5034411A (no)
EP (2) EP0322389B1 (no)
JP (2) JPH0637458B2 (no)
KR (2) KR900700441A (no)
CN (3) CN1033804A (no)
AR (1) AR247729A1 (no)
AT (2) ATE81848T1 (no)
AU (4) AU625774B2 (no)
DD (2) DD277274A5 (no)
DE (2) DE3875600T2 (no)
DK (2) DK404789A (no)
EG (1) EG18681A (no)
ES (2) ES2043891T3 (no)
FI (2) FI893937A (no)
GR (2) GR3006241T3 (no)
HU (3) HU913679D0 (no)
IE (2) IE883860L (no)
IL (2) IL88749A (no)
IS (1) IS1558B (no)
LT (4) LTIP1687A (no)
LV (1) LV10250A (no)
MX (1) MX174084B (no)
MY (1) MY103945A (no)
NO (2) NO171784C (no)
NZ (1) NZ227381A (no)
PH (2) PH25526A (no)
PL (2) PL159551B1 (no)
PT (2) PT89311B (no)
RU (3) RU2024503C1 (no)
SE (1) SE8705150D0 (no)
WO (3) WO1989005795A1 (no)
YU (2) YU47580B (no)
ZA (2) ZA889424B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8705150D0 (sv) * 1987-12-23 1987-12-23 Haessle Ab Novel antiarrhythmic agents
SE8902237D0 (sv) * 1989-06-20 1989-06-20 Haessle Ab Novel stereoisomers
SE8902236D0 (sv) * 1989-06-20 1989-06-20 Haessle Ab Novel polystyrenesulfonate
SE8902235D0 (sv) * 1989-06-20 1989-06-20 Haessle Ab Novel cyclodextrin inclusion complexes
SE9003902D0 (sv) * 1990-12-07 1990-12-07 Astra Ab Solid dosage forms of a drug
US5084463A (en) * 1989-12-11 1992-01-28 American Home Products Corporation N-quinolinyl alkyl-substituted 1-aryloxy-2-propanolamine and propylamine derivatives possessing class III antiarrhythmic activity
US5619274A (en) * 1990-09-10 1997-04-08 Starsight Telecast, Inc. Television schedule information transmission and utilization system and process
UA26190C2 (uk) * 1992-07-28 1999-07-19 Сейфтек Ай Лімітед Шприц
US5679706A (en) * 1994-09-30 1997-10-21 Bristol-Myers Squibb Company Combination of a potassium channel activator and an antiarrhythmic agent
US6143569A (en) * 1998-08-31 2000-11-07 The United States Of America As Represented By The Secretary Of The Navy Chelators exhibiting triple fluorescence
GB0123961D0 (en) * 2001-10-05 2001-11-28 Astrazeneca Ab Process and intermediates
US7465738B2 (en) 2003-06-16 2008-12-16 Vertex Pharmaceuticals Incorporated Compounds useful as promoters of SMN2
WO2005007215A2 (en) * 2003-07-09 2005-01-27 Glucolight Corporation Method and apparatus for tissue oximetry
RU2631231C1 (ru) * 2016-12-01 2017-09-19 Научно-производственная ассоциация "Технопарк Авиационных Технологий" Способ получения заготовки лопатки газотурбинного двигателя для линейной сварки трением
CN115417973B (zh) * 2022-11-03 2023-03-24 广东粤港澳大湾区黄埔材料研究院 抗菌聚氨酯材料及其制备方法和应用

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US3149147A (en) * 1961-03-16 1964-09-15 Smith Kline French Lab Novel substituted phenylalkylamines
FR152F (no) * 1962-01-24
GB1069345A (en) * 1963-07-19 1967-05-17 Ici Ltd New alkanolamine derivatives
DE1593771A1 (de) * 1967-04-06 1970-04-30 Boehringer Sohn Ingelheim Verfahren zur Herstellung von 1-Phenoxy-2-amino-alkanen
BE757005A (fr) * 1969-10-02 1971-04-02 Bristol Myers Co Phenethanolamines substituees et procede pour leur preparation
GB1457876A (en) * 1972-12-15 1976-12-08 Ici Ltd Alkanolamine derivatives device for use in
SE404793B (sv) * 1973-05-25 1978-10-30 Boehringer Sohn Ingelheim Forfarande for framstellning av vissa angivna nitrilsubstituerade 1-fenoxi-2-hydroxi-3-lagalkylaminopropaner
GB1433920A (en) * 1973-10-01 1976-04-28 Ici Ltd Alkanolamine derivatives
FR2280376A1 (fr) * 1974-08-02 1976-02-27 Sogeras Nouveaux derives du piperidine-4 ethanol
DE2503222A1 (de) * 1975-01-27 1976-07-29 Boehringer Sohn Ingelheim Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten
SE421123B (sv) * 1976-08-25 1981-11-30 Boehringer Sohn Ingelheim Forfarande for framstellning av vissa angivna nitrilsubstituerade 1-fenoxi-2-hydroxi-3-alkylaminopropaner
US4283534A (en) * 1979-04-11 1981-08-11 Basf Aktiengesellschaft Reductive alkylation of nitrogen heterocycles
US4544654A (en) * 1984-03-20 1985-10-01 Schering A.G. Substituted sulfonamidobenzamides, antiarrhythmic agents and compositions thereof
US4614746A (en) * 1985-03-21 1986-09-30 American Cyanamid Company 5-fluorobenzonitrile derivatives for increasing the lean meat to fat ratio and/or enhancing the growth rate of warm-blooded animals
CA1267416A (en) * 1985-06-17 1990-04-03 Ila Sircar 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders
EG18188A (en) * 1986-05-01 1992-09-30 Pfizer Ltd Process for preparation anti-arhythmia agents
SE8705150D0 (sv) * 1987-12-23 1987-12-23 Haessle Ab Novel antiarrhythmic agents
SE8902236D0 (sv) * 1989-06-20 1989-06-20 Haessle Ab Novel polystyrenesulfonate
SE8902237D0 (sv) * 1989-06-20 1989-06-20 Haessle Ab Novel stereoisomers

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CN1048214A (zh) 1991-01-02
MX14310A (es) 1993-10-01
KR900700442A (ko) 1990-08-13
FI92192C (sv) 1994-10-10
PT89312B (pt) 1993-08-31
LV10250A (lv) 1994-10-20
EP0322389B1 (en) 1992-10-28
ES2043891T3 (es) 1994-01-01
GR3006912T3 (no) 1993-06-30
FI893937A0 (fi) 1989-08-22
AU2910389A (en) 1989-07-19
FI893936A0 (fi) 1989-08-22
US5155133A (en) 1992-10-13
LTIP1687A (en) 1995-07-25
JPH02502725A (ja) 1990-08-30
DE3875600T2 (de) 1993-03-11
PT89312A (pt) 1989-12-29
PL157747B1 (pl) 1992-06-30
YU234088A (en) 1990-06-30
DD277274A5 (de) 1990-03-28
EP0322390A2 (en) 1989-06-28
RU1836342C (ru) 1993-08-23
IS1558B (is) 1994-10-05
IS3425A7 (is) 1989-06-24
ZA889424B (en) 1989-08-30
NO171784B (no) 1993-01-25
PL159551B1 (pl) 1992-12-31
HUT54346A (en) 1991-02-28
GR3006241T3 (no) 1993-06-21
EP0322389A2 (en) 1989-06-28
EP0322390B1 (en) 1992-11-11
AU2824489A (en) 1989-07-19
JPH0637458B2 (ja) 1994-05-18
YU19690A (en) 1992-05-28
PT89311A (pt) 1989-12-29
RU2024503C1 (ru) 1994-12-15
JPH02502726A (ja) 1990-08-30
AU625872B2 (en) 1992-07-16
RU1836343C (ru) 1993-08-23
MY103945A (en) 1993-10-30
KR900700441A (ko) 1990-08-13
PL276698A1 (en) 1989-08-07
AU625774B2 (en) 1992-07-16
YU47580B (sh) 1995-10-24
FI893937A (fi) 1989-08-22
NO171724B (no) 1993-01-18
DE3875600D1 (de) 1992-12-03
DK404889D0 (da) 1989-08-17
CN1033804A (zh) 1989-07-12
PH25526A (en) 1991-07-24
ATE82257T1 (de) 1992-11-15
NO171724C (no) 1993-04-28
WO1989005806A1 (en) 1989-06-29
WO1989005795A1 (en) 1989-06-29
CN1097736A (zh) 1995-01-25
ATE81848T1 (de) 1992-11-15
NO893375L (no) 1989-08-22
LTIP1688A (en) 1995-07-25
NO893375D0 (no) 1989-08-22
NO893376D0 (no) 1989-08-22
NO893376L (no) 1989-08-22
PH26828A (en) 1992-11-05
ES2045189T3 (es) 1994-01-16
EP0322389A3 (en) 1989-09-06
IE883859L (en) 1989-06-23
MX174084B (es) 1994-04-20
AR247729A1 (es) 1995-03-31
EG18681A (en) 1993-10-30
FI92192B (fi) 1994-06-30
DE3875934D1 (de) 1992-12-17
DD295353A5 (de) 1991-10-31
IE883860L (en) 1989-06-23
NO171784C (no) 1993-05-05
HU205895B (en) 1992-07-28
IL103741A (en) 1994-04-12
WO1989005794A1 (en) 1989-06-29
NZ227381A (en) 1992-07-28
US5034411A (en) 1991-07-23
LTIP1720A (en) 1995-07-25
AU2824189A (en) 1989-07-19
IL88749A (en) 1994-04-12
ZA894441B (en) 1990-02-28
HUT54345A (en) 1991-02-28
HU913679D0 (en) 1992-02-28
FI893936A (fi) 1989-08-22
DE3875934T2 (de) 1993-03-25
DK404889A (da) 1989-10-19
PT89311B (pt) 1993-08-31
EP0322390A3 (en) 1989-09-06
DK404789A (da) 1989-10-19
DK404789D0 (da) 1989-08-17
LTIP1752A (en) 1995-07-25

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