SE8305123D0 - Biologiskt aktiva tripeptid- och tetrapeptid-alkylamider, sett for framstellning derav och farmaceutiska kompositioner innehallande desamma - Google Patents
Biologiskt aktiva tripeptid- och tetrapeptid-alkylamider, sett for framstellning derav och farmaceutiska kompositioner innehallande desammaInfo
- Publication number
- SE8305123D0 SE8305123D0 SE8305123A SE8305123A SE8305123D0 SE 8305123 D0 SE8305123 D0 SE 8305123D0 SE 8305123 A SE8305123 A SE 8305123A SE 8305123 A SE8305123 A SE 8305123A SE 8305123 D0 SE8305123 D0 SE 8305123D0
- Authority
- SE
- Sweden
- Prior art keywords
- alkylamides
- tetrapeptide
- carbon atoms
- preparation
- pharmaceutical compositions
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 2
- 235000004279 alanine Nutrition 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 206010014561 Emphysema Diseases 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 102000016387 Pancreatic elastase Human genes 0.000 abstract 1
- 108010067372 Pancreatic elastase Proteins 0.000 abstract 1
- 206010033645 Pancreatitis Diseases 0.000 abstract 1
- 206010033647 Pancreatitis acute Diseases 0.000 abstract 1
- 201000003229 acute pancreatitis Diseases 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- -1 benzyloxycarbonylamino group Chemical group 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS827013A CS231228B1 (en) | 1982-10-01 | 1982-10-01 | Biologically effective tri and tetrapeptide alkylamide derivatives and their processing method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8305123D0 true SE8305123D0 (sv) | 1983-09-22 |
| SE8305123L SE8305123L (sv) | 1984-04-02 |
| SE457087B SE457087B (sv) | 1988-11-28 |
Family
ID=5418471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8305123A SE457087B (sv) | 1982-10-01 | 1983-09-22 | Biologiskt aktiva tripeptid- och tetrapeptid-alkylamider och farmaceutiska kompositioner innehaallande desamma |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4528133A (sv) |
| JP (1) | JPS5978150A (sv) |
| BE (1) | BE897844A (sv) |
| CA (1) | CA1243306A (sv) |
| CH (1) | CH658251A5 (sv) |
| CS (1) | CS231228B1 (sv) |
| DE (1) | DE3335865A1 (sv) |
| FR (1) | FR2533920B1 (sv) |
| GB (1) | GB2127830B (sv) |
| HU (1) | HU193048B (sv) |
| IT (1) | IT1171092B (sv) |
| SE (1) | SE457087B (sv) |
| YU (1) | YU195383A (sv) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5444042A (en) * | 1990-12-28 | 1995-08-22 | Cortex Pharmaceuticals | Method of treatment of neurodegeneration with calpain inhibitors |
| IL108031A0 (en) * | 1992-12-22 | 1994-04-12 | Procter & Gamble | Difluoro pentapeptide derivatives and pharmaceutical compositions containing them |
| CZ285911B6 (cs) * | 1997-04-30 | 1999-11-17 | Vúfb, A. S. | Oligopeptidické inhibitory elastáz |
| JP2000256396A (ja) | 1999-03-03 | 2000-09-19 | Dainippon Pharmaceut Co Ltd | 複素環式化合物およびその中間体ならびにエラスターゼ阻害剤 |
| PL354122A1 (en) * | 1999-08-09 | 2003-12-29 | Tripep Abtripep Ab | Pharmaceutical compositions containing tripeptides |
| DE60023931T2 (de) * | 1999-10-18 | 2006-08-03 | Firmenich S.A. | Ester mit einer sekundären carbamoylgruppe und deren verwendung als ausgangsstoffe von duftenden alkoholen |
| US6593455B2 (en) * | 2001-08-24 | 2003-07-15 | Tripep Ab | Tripeptide amides that block viral infectivity and methods of use thereof |
| WO2003024995A1 (en) * | 2001-09-19 | 2003-03-27 | Tripep Ab | Molecules that block viral infectivity and methods of use thereof |
| US20050096319A1 (en) * | 2003-02-21 | 2005-05-05 | Balzarini Jan M.R. | Identification of compounds that inhibit replication of human immunodeficiency virus |
| US20040180893A1 (en) * | 2003-02-21 | 2004-09-16 | Balzarini Jan Maria Rene | Identification of compounds that inhibit replication of human immunodeficiency virus |
| US20170043197A1 (en) * | 2014-09-16 | 2017-02-16 | Massachusetts Institute Of Technology | Block Copolymer Complex Coacervate Core Micelles for Enzymatic Catalysis in Organic Solvent |
| BR112018076309A8 (pt) | 2016-06-17 | 2022-06-28 | Univ Erasmus Med Ct Rotterdam | Compostos de geminóide e seus usos |
| WO2022235051A1 (ko) | 2021-05-03 | 2022-11-10 | 한국화학연구원 | 에스테르 작용기를 포함하는 유색 고분자로부터 색을 발현하는 이물질을 제거하기 위한 추출제, 추출 방법 및 유색 고분자 혼합물로부터 에스테르 작용기를 포함하는 고분자를 화학적으로 선별하는 방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3972773A (en) * | 1975-04-29 | 1976-08-03 | Sagami Chemical Research Center | Process for producing peptide |
| PH14141A (en) * | 1976-06-25 | 1981-03-05 | Hoffmann La Roche | Pharmaceutical composition containing dipeptide derivatives |
| US4167449A (en) * | 1976-07-29 | 1979-09-11 | American Hospital Supply Corporation | Composition and method for determining transferase and protease activity |
| US4155916A (en) * | 1977-08-29 | 1979-05-22 | Dolbeare Frank A | Fluorescence method for enzyme analysis which couples aromatic amines with aromatic aldehydes |
| US4276298A (en) * | 1978-03-24 | 1981-06-30 | Merck & Co., Inc. | 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors |
| US4336186A (en) * | 1978-08-03 | 1982-06-22 | Gargiulo Robert J | Analytical fluorogenic substrates for proteolytic enzymes |
| US4275153A (en) * | 1978-08-03 | 1981-06-23 | American Hospital Supply Corporation | Analytical fluorogenic substrates for proteolytic enzymes |
| CS226907B1 (en) * | 1981-08-07 | 1984-04-16 | Kasafirek Evzen | Alkylamides of carboxyalkanoylpeptides |
| US4371466A (en) * | 1981-10-07 | 1983-02-01 | American Home Products Corporation | Mammalian collagenase inhibitors |
-
1982
- 1982-10-01 CS CS827013A patent/CS231228B1/cs unknown
-
1983
- 1983-09-19 GB GB08324970A patent/GB2127830B/en not_active Expired
- 1983-09-22 SE SE8305123A patent/SE457087B/sv not_active IP Right Cessation
- 1983-09-22 JP JP58174386A patent/JPS5978150A/ja active Granted
- 1983-09-26 CH CH5209/83A patent/CH658251A5/de not_active IP Right Cessation
- 1983-09-27 CA CA000437638A patent/CA1243306A/en not_active Expired
- 1983-09-27 BE BE0/211590A patent/BE897844A/fr not_active IP Right Cessation
- 1983-09-29 IT IT23059/83A patent/IT1171092B/it active
- 1983-09-29 YU YU01953/83A patent/YU195383A/xx unknown
- 1983-09-30 HU HU833420A patent/HU193048B/hu not_active IP Right Cessation
- 1983-09-30 FR FR8315600A patent/FR2533920B1/fr not_active Expired
- 1983-10-03 DE DE19833335865 patent/DE3335865A1/de active Granted
- 1983-10-03 US US06/538,095 patent/US4528133A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0359919B2 (sv) | 1991-09-12 |
| YU195383A (en) | 1986-08-31 |
| IT8323059A1 (it) | 1985-03-29 |
| SE8305123L (sv) | 1984-04-02 |
| DE3335865C2 (sv) | 1991-03-14 |
| HU193048B (en) | 1987-08-28 |
| SE457087B (sv) | 1988-11-28 |
| CS231228B1 (en) | 1984-10-15 |
| GB8324970D0 (en) | 1983-10-19 |
| GB2127830B (en) | 1986-08-13 |
| FR2533920A1 (fr) | 1984-04-06 |
| JPS5978150A (ja) | 1984-05-04 |
| BE897844A (fr) | 1984-01-16 |
| CH658251A5 (de) | 1986-10-31 |
| CA1243306A (en) | 1988-10-18 |
| DE3335865A1 (de) | 1984-04-05 |
| GB2127830A (en) | 1984-04-18 |
| IT8323059A0 (it) | 1983-09-29 |
| FR2533920B1 (fr) | 1986-08-14 |
| US4528133A (en) | 1985-07-09 |
| IT1171092B (it) | 1987-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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