FR2533920B1 - Tripeptide- et tetrapeptide-alkylamides a activite biologique, utiles comme medicaments et procedes pour leur preparation - Google Patents

Tripeptide- et tetrapeptide-alkylamides a activite biologique, utiles comme medicaments et procedes pour leur preparation

Info

Publication number
FR2533920B1
FR2533920B1 FR8315600A FR8315600A FR2533920B1 FR 2533920 B1 FR2533920 B1 FR 2533920B1 FR 8315600 A FR8315600 A FR 8315600A FR 8315600 A FR8315600 A FR 8315600A FR 2533920 B1 FR2533920 B1 FR 2533920B1
Authority
FR
France
Prior art keywords
alkylamides
tetrapeptide
tripeptide
medicaments
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8315600A
Other languages
English (en)
Other versions
FR2533920A1 (fr
Inventor
Evzen Kasafirek
Premysl Fric
Jan Slaby
Alena Roubalova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spofa Vereinigte Pharma Werke
Original Assignee
Spofa Vereinigte Pharma Werke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Vereinigte Pharma Werke filed Critical Spofa Vereinigte Pharma Werke
Publication of FR2533920A1 publication Critical patent/FR2533920A1/fr
Application granted granted Critical
Publication of FR2533920B1 publication Critical patent/FR2533920B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR8315600A 1982-10-01 1983-09-30 Tripeptide- et tetrapeptide-alkylamides a activite biologique, utiles comme medicaments et procedes pour leur preparation Expired FR2533920B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS827013A CS231228B1 (en) 1982-10-01 1982-10-01 Biologically effective tri and tetrapeptide alkylamide derivatives and their processing method

Publications (2)

Publication Number Publication Date
FR2533920A1 FR2533920A1 (fr) 1984-04-06
FR2533920B1 true FR2533920B1 (fr) 1986-08-14

Family

ID=5418471

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8315600A Expired FR2533920B1 (fr) 1982-10-01 1983-09-30 Tripeptide- et tetrapeptide-alkylamides a activite biologique, utiles comme medicaments et procedes pour leur preparation

Country Status (13)

Country Link
US (1) US4528133A (fr)
JP (1) JPS5978150A (fr)
BE (1) BE897844A (fr)
CA (1) CA1243306A (fr)
CH (1) CH658251A5 (fr)
CS (1) CS231228B1 (fr)
DE (1) DE3335865A1 (fr)
FR (1) FR2533920B1 (fr)
GB (1) GB2127830B (fr)
HU (1) HU193048B (fr)
IT (1) IT1171092B (fr)
SE (1) SE457087B (fr)
YU (1) YU195383A (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5444042A (en) * 1990-12-28 1995-08-22 Cortex Pharmaceuticals Method of treatment of neurodegeneration with calpain inhibitors
IL108031A0 (en) * 1992-12-22 1994-04-12 Procter & Gamble Difluoro pentapeptide derivatives and pharmaceutical compositions containing them
CZ285911B6 (cs) * 1997-04-30 1999-11-17 Vúfb, A. S. Oligopeptidické inhibitory elastáz
JP2000256396A (ja) 1999-03-03 2000-09-19 Dainippon Pharmaceut Co Ltd 複素環式化合物およびその中間体ならびにエラスターゼ阻害剤
CZ2002421A3 (cs) * 1999-08-09 2002-09-11 Tripep Ab Prostředek pro potlačení aktivace transkripce, represe transkripce, sestavování bakteriálního holotoxinu, polymerizace aktinu, agregace beta-amyloidního peptidu, sestavování tubulínového komplexu, způsob potlačení, způsob léčby a prevence lidských chorob, Alzheimerovy choroby a rakoviny, způsob přípravy léčiva a léčivo
BR0014806A (pt) * 1999-10-18 2002-06-11 Firmenich & Cie Composição perfumante ou artigo perfumado, utilização de um composto, processos para a perfumação de têxteis, e para intensificar ou prolongar o efeito de difusão do odor caracterìstico de um álcool odorante desenvolvido para têxteis, e, composto
US6593455B2 (en) * 2001-08-24 2003-07-15 Tripep Ab Tripeptide amides that block viral infectivity and methods of use thereof
EP1436317A1 (fr) * 2001-09-19 2004-07-14 Tripep Ab Molecules bloquant l'infectivite virale et methodes d'utilisation associees
PL378163A1 (pl) * 2003-02-21 2006-03-06 Tripep Ab Pochodna glicynoamidu do hamowania replikacji HIV
US20050096319A1 (en) * 2003-02-21 2005-05-05 Balzarini Jan M.R. Identification of compounds that inhibit replication of human immunodeficiency virus
WO2016044400A1 (fr) * 2014-09-16 2016-03-24 Massachusetts Institute Of Technology Micelles à noyau de coacervat complexe à copolymère bloc pour la catalyse enzymatique dans un solvant organique
WO2017217855A1 (fr) 2016-06-17 2017-12-21 Erasmus University Medical Center Rotterdam Composés géminoïdes lipopeptides et leurs utilisations
WO2022235051A1 (fr) 2021-05-03 2022-11-10 한국화학연구원 Agent d'extraction et procédé d'extraction pour l'élimination de substances étrangères conférant de la couleur d'un polymère coloré contenant un groupe fonctionnel ester et procédé pour la sélection chimique d'un polymère contenant un groupe fonctionnel ester à partir d'un mélange à base de polymère coloré

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972773A (en) * 1975-04-29 1976-08-03 Sagami Chemical Research Center Process for producing peptide
CH627735A5 (de) * 1976-06-25 1982-01-29 Hoffmann La Roche Verfahren zur herstellung von dipeptidderivaten.
US4167449A (en) * 1976-07-29 1979-09-11 American Hospital Supply Corporation Composition and method for determining transferase and protease activity
US4155916A (en) * 1977-08-29 1979-05-22 Dolbeare Frank A Fluorescence method for enzyme analysis which couples aromatic amines with aromatic aldehydes
US4276298A (en) * 1978-03-24 1981-06-30 Merck & Co., Inc. 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors
US4336186A (en) * 1978-08-03 1982-06-22 Gargiulo Robert J Analytical fluorogenic substrates for proteolytic enzymes
US4275153A (en) * 1978-08-03 1981-06-23 American Hospital Supply Corporation Analytical fluorogenic substrates for proteolytic enzymes
CS226907B1 (en) * 1981-08-07 1984-04-16 Kasafirek Evzen Alkylamides of carboxyalkanoylpeptides
US4371466A (en) * 1981-10-07 1983-02-01 American Home Products Corporation Mammalian collagenase inhibitors

Also Published As

Publication number Publication date
GB2127830A (en) 1984-04-18
DE3335865C2 (fr) 1991-03-14
GB8324970D0 (en) 1983-10-19
SE457087B (sv) 1988-11-28
CS231228B1 (en) 1984-10-15
YU195383A (en) 1986-08-31
GB2127830B (en) 1986-08-13
IT8323059A1 (it) 1985-03-29
FR2533920A1 (fr) 1984-04-06
JPS5978150A (ja) 1984-05-04
SE8305123D0 (sv) 1983-09-22
DE3335865A1 (de) 1984-04-05
CA1243306A (fr) 1988-10-18
IT1171092B (it) 1987-06-10
US4528133A (en) 1985-07-09
IT8323059A0 (it) 1983-09-29
SE8305123L (sv) 1984-04-02
CH658251A5 (de) 1986-10-31
JPH0359919B2 (fr) 1991-09-12
HU193048B (en) 1987-08-28
BE897844A (fr) 1984-01-16

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Legal Events

Date Code Title Description
ST Notification of lapse