IT1171092B - Tripeptide e tetrapeptide alchilamidi biologicamente attive,processi per la loro preparazione e composizioni farmaceutiche che le contengono - Google Patents

Tripeptide e tetrapeptide alchilamidi biologicamente attive,processi per la loro preparazione e composizioni farmaceutiche che le contengono

Info

Publication number
IT1171092B
IT1171092B IT23059/83A IT2305983A IT1171092B IT 1171092 B IT1171092 B IT 1171092B IT 23059/83 A IT23059/83 A IT 23059/83A IT 2305983 A IT2305983 A IT 2305983A IT 1171092 B IT1171092 B IT 1171092B
Authority
IT
Italy
Prior art keywords
alchylamids
tetrapeptide
tripeptide
processes
preparation
Prior art date
Application number
IT23059/83A
Other languages
English (en)
Other versions
IT8323059A1 (it
IT8323059A0 (it
Inventor
Evzen Kasafirek
Premysl Fric
Jan Slaby
Alena Roubalova
Original Assignee
Spofa Spojene Podniky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Spojene Podniky filed Critical Spofa Spojene Podniky
Publication of IT8323059A0 publication Critical patent/IT8323059A0/it
Publication of IT8323059A1 publication Critical patent/IT8323059A1/it
Application granted granted Critical
Publication of IT1171092B publication Critical patent/IT1171092B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT23059/83A 1982-10-01 1983-09-29 Tripeptide e tetrapeptide alchilamidi biologicamente attive,processi per la loro preparazione e composizioni farmaceutiche che le contengono IT1171092B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS827013A CS231228B1 (en) 1982-10-01 1982-10-01 Biologically effective tri and tetrapeptide alkylamide derivatives and their processing method

Publications (3)

Publication Number Publication Date
IT8323059A0 IT8323059A0 (it) 1983-09-29
IT8323059A1 IT8323059A1 (it) 1985-03-29
IT1171092B true IT1171092B (it) 1987-06-10

Family

ID=5418471

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23059/83A IT1171092B (it) 1982-10-01 1983-09-29 Tripeptide e tetrapeptide alchilamidi biologicamente attive,processi per la loro preparazione e composizioni farmaceutiche che le contengono

Country Status (13)

Country Link
US (1) US4528133A (it)
JP (1) JPS5978150A (it)
BE (1) BE897844A (it)
CA (1) CA1243306A (it)
CH (1) CH658251A5 (it)
CS (1) CS231228B1 (it)
DE (1) DE3335865A1 (it)
FR (1) FR2533920B1 (it)
GB (1) GB2127830B (it)
HU (1) HU193048B (it)
IT (1) IT1171092B (it)
SE (1) SE457087B (it)
YU (1) YU195383A (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5444042A (en) * 1990-12-28 1995-08-22 Cortex Pharmaceuticals Method of treatment of neurodegeneration with calpain inhibitors
IL108031A0 (en) * 1992-12-22 1994-04-12 Procter & Gamble Difluoro pentapeptide derivatives and pharmaceutical compositions containing them
CZ285911B6 (cs) * 1997-04-30 1999-11-17 Vúfb, A. S. Oligopeptidické inhibitory elastáz
JP2000256396A (ja) 1999-03-03 2000-09-19 Dainippon Pharmaceut Co Ltd 複素環式化合物およびその中間体ならびにエラスターゼ阻害剤
CZ2002421A3 (cs) * 1999-08-09 2002-09-11 Tripep Ab Prostředek pro potlačení aktivace transkripce, represe transkripce, sestavování bakteriálního holotoxinu, polymerizace aktinu, agregace beta-amyloidního peptidu, sestavování tubulínového komplexu, způsob potlačení, způsob léčby a prevence lidských chorob, Alzheimerovy choroby a rakoviny, způsob přípravy léčiva a léčivo
BR0014806A (pt) * 1999-10-18 2002-06-11 Firmenich & Cie Composição perfumante ou artigo perfumado, utilização de um composto, processos para a perfumação de têxteis, e para intensificar ou prolongar o efeito de difusão do odor caracterìstico de um álcool odorante desenvolvido para têxteis, e, composto
US6593455B2 (en) * 2001-08-24 2003-07-15 Tripep Ab Tripeptide amides that block viral infectivity and methods of use thereof
EP1436317A1 (en) * 2001-09-19 2004-07-14 Tripep Ab Molecules that block viral infectivity and methods of use thereof
PL378163A1 (pl) * 2003-02-21 2006-03-06 Tripep Ab Pochodna glicynoamidu do hamowania replikacji HIV
US20050096319A1 (en) * 2003-02-21 2005-05-05 Balzarini Jan M.R. Identification of compounds that inhibit replication of human immunodeficiency virus
WO2016044400A1 (en) * 2014-09-16 2016-03-24 Massachusetts Institute Of Technology Block copolymer complex coacervate core micelles for enzymatic catalysis in organic solvent
WO2017217855A1 (en) 2016-06-17 2017-12-21 Erasmus University Medical Center Rotterdam Geminoid lipopeptide compounds and their uses
WO2022235051A1 (ko) 2021-05-03 2022-11-10 한국화학연구원 에스테르 작용기를 포함하는 유색 고분자로부터 색을 발현하는 이물질을 제거하기 위한 추출제, 추출 방법 및 유색 고분자 혼합물로부터 에스테르 작용기를 포함하는 고분자를 화학적으로 선별하는 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972773A (en) * 1975-04-29 1976-08-03 Sagami Chemical Research Center Process for producing peptide
CH627735A5 (de) * 1976-06-25 1982-01-29 Hoffmann La Roche Verfahren zur herstellung von dipeptidderivaten.
US4167449A (en) * 1976-07-29 1979-09-11 American Hospital Supply Corporation Composition and method for determining transferase and protease activity
US4155916A (en) * 1977-08-29 1979-05-22 Dolbeare Frank A Fluorescence method for enzyme analysis which couples aromatic amines with aromatic aldehydes
US4276298A (en) * 1978-03-24 1981-06-30 Merck & Co., Inc. 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors
US4336186A (en) * 1978-08-03 1982-06-22 Gargiulo Robert J Analytical fluorogenic substrates for proteolytic enzymes
US4275153A (en) * 1978-08-03 1981-06-23 American Hospital Supply Corporation Analytical fluorogenic substrates for proteolytic enzymes
CS226907B1 (en) * 1981-08-07 1984-04-16 Kasafirek Evzen Alkylamides of carboxyalkanoylpeptides
US4371466A (en) * 1981-10-07 1983-02-01 American Home Products Corporation Mammalian collagenase inhibitors

Also Published As

Publication number Publication date
GB2127830A (en) 1984-04-18
DE3335865C2 (it) 1991-03-14
FR2533920B1 (fr) 1986-08-14
GB8324970D0 (en) 1983-10-19
SE457087B (sv) 1988-11-28
CS231228B1 (en) 1984-10-15
YU195383A (en) 1986-08-31
GB2127830B (en) 1986-08-13
IT8323059A1 (it) 1985-03-29
FR2533920A1 (fr) 1984-04-06
JPS5978150A (ja) 1984-05-04
SE8305123D0 (sv) 1983-09-22
DE3335865A1 (de) 1984-04-05
CA1243306A (en) 1988-10-18
US4528133A (en) 1985-07-09
IT8323059A0 (it) 1983-09-29
SE8305123L (sv) 1984-04-02
CH658251A5 (de) 1986-10-31
JPH0359919B2 (it) 1991-09-12
HU193048B (en) 1987-08-28
BE897844A (fr) 1984-01-16

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