DK403384A - Enteralt effektivt, biologisk aktivt peptid- eller proteinmiddel ogfremgangsmaader til fremstilling deraf - Google Patents

Enteralt effektivt, biologisk aktivt peptid- eller proteinmiddel ogfremgangsmaader til fremstilling deraf Download PDF

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Publication number
DK403384A
DK403384A DK403384A DK403384A DK403384A DK 403384 A DK403384 A DK 403384A DK 403384 A DK403384 A DK 403384A DK 403384 A DK403384 A DK 403384A DK 403384 A DK403384 A DK 403384A
Authority
DK
Denmark
Prior art keywords
enterally
procedures
producing
effective
biologically active
Prior art date
Application number
DK403384A
Other languages
English (en)
Other versions
DK403384D0 (da
Inventor
Lin-Nar L Teng
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of DK403384D0 publication Critical patent/DK403384D0/da
Publication of DK403384A publication Critical patent/DK403384A/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/541—Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK403384A 1982-12-23 1984-08-23 Enteralt effektivt, biologisk aktivt peptid- eller proteinmiddel ogfremgangsmaader til fremstilling deraf DK403384A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/452,493 US4582820A (en) 1982-12-23 1982-12-23 Orally administered biologically active peptides and proteins
PCT/US1983/001941 WO1984002467A1 (en) 1982-12-23 1983-12-12 Orally administered biologically active peptides and proteins

Publications (2)

Publication Number Publication Date
DK403384D0 DK403384D0 (da) 1984-08-23
DK403384A true DK403384A (da) 1984-08-23

Family

ID=23796678

Family Applications (1)

Application Number Title Priority Date Filing Date
DK403384A DK403384A (da) 1982-12-23 1984-08-23 Enteralt effektivt, biologisk aktivt peptid- eller proteinmiddel ogfremgangsmaader til fremstilling deraf

Country Status (6)

Country Link
US (1) US4582820A (da)
EP (1) EP0129582A4 (da)
JP (1) JPS60500289A (da)
CA (1) CA1232267A (da)
DK (1) DK403384A (da)
WO (1) WO1984002467A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604376A (en) * 1982-04-21 1986-08-05 Research Corporation Enteric compounds and complexes
US6156731A (en) * 1989-05-10 2000-12-05 G. D. Searle & Co. Polypeptide composition for oral administration
US5015626A (en) * 1989-08-02 1991-05-14 Iowa State University Research Foundation, Inc. Porcine somatotropin to improve meat quality of pigs
US5015627A (en) * 1990-07-20 1991-05-14 Smithkline Beecham Corporation Stabilized somatotropin for parenteral administration
WO1995002411A1 (en) * 1993-07-16 1995-01-26 Mallinckrodt Veterinary Limited Stabilised polypeptide growth factor formulation at low ph
US5821219A (en) * 1995-08-11 1998-10-13 Oregon Health Sciences University Opioid antagonists and methods of their use
US6221378B1 (en) 1998-02-10 2001-04-24 Generex Pharmaceuticals Incorporated Mixed micellar delivery system and method of preparation
US7070799B1 (en) * 1998-02-10 2006-07-04 Generex Pharmaceuticals, Inc. Method for administering insulin to the buccal region
JP2002506876A (ja) * 1998-03-18 2002-03-05 ユニバーシティ テクノロジー コーポレーション 非晶質ポリマーを含む持続放出性組成物
US6613358B2 (en) 1998-03-18 2003-09-02 Theodore W. Randolph Sustained-release composition including amorphous polymer
US6294153B1 (en) 1998-12-21 2001-09-25 Generex Pharmaceuticals, Inc. Aerosol pharmaceutical formulation for pulmonary and nasal delivery
US6350432B1 (en) 1999-03-19 2002-02-26 Generex Pharmaceuticals Incorporated Pressurized container having an aerosolized pharmaceutical composition
US7517669B2 (en) * 2000-11-01 2009-04-14 Broyles Robert H Gene regulation therapy involving ferritin
US7060675B2 (en) * 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
US9089521B2 (en) * 2001-11-01 2015-07-28 Robert H. Broyles Method for regulating production of hemoglobin beta chains

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2108765A (en) * 1938-02-15 Preserving and disinfecting media
CH201759A (de) * 1936-01-07 1938-12-15 Fritz Dr Lasch Mittel zum Schutze von Heilmitteln, insbesondere Insulin, gegen vorzeitige Zerstörung im Magen und Darm.
US2694663A (en) * 1950-09-05 1954-11-16 California Research Corp Synergistic microbicidal compositions
US2844466A (en) * 1953-10-02 1958-07-22 Armour & Co Growth promotant substances
US2907693A (en) * 1956-04-30 1959-10-06 Pfizer & Co C Antibacterial compositions comprising a tetracycline-type antibiotic and an alkyl phenoxyethoxyethyl dialkylbenzyl ammonium salt
US3058884A (en) * 1959-09-14 1962-10-16 Abbott Lab Process for purifying heparin
US3160563A (en) * 1960-05-13 1964-12-08 Ormonoterapia Richter Spa Purification of heaprin
US3869550A (en) * 1972-05-01 1975-03-04 Environmental Science Corp Method for the control of fertility
US4153689A (en) * 1975-06-13 1979-05-08 Takeda Chemical Industries, Ltd. Stable insulin preparation for nasal administration
GB1563311A (en) * 1975-09-26 1980-03-26 Yamanouchi Pharma Co Ltd Pharmaceutical composition of insulin for rectal use
US4277465A (en) * 1978-08-26 1981-07-07 Kyoto Yakuhin Kogyo Kabushiki Kaisha Adjuvant for promoting absorption of therapeutically active substances through the digestive tract
JPS55113723A (en) * 1979-02-26 1980-09-02 Ko Kamata Drug composition to be absorbed in digestive canal

Also Published As

Publication number Publication date
JPS60500289A (ja) 1985-03-07
EP0129582A4 (en) 1987-09-02
DK403384D0 (da) 1984-08-23
CA1232267A (en) 1988-02-02
WO1984002467A1 (en) 1984-07-05
EP0129582A1 (en) 1985-01-02
US4582820A (en) 1986-04-15

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment