DE69203551T2 - Biologisch abbaubarer Copolyester von 4-Hydroxyprolin und diesen enthaltende pharmazeutische Zusammensetzung. - Google Patents

Biologisch abbaubarer Copolyester von 4-Hydroxyprolin und diesen enthaltende pharmazeutische Zusammensetzung.

Info

Publication number
DE69203551T2
DE69203551T2 DE69203551T DE69203551T DE69203551T2 DE 69203551 T2 DE69203551 T2 DE 69203551T2 DE 69203551 T DE69203551 T DE 69203551T DE 69203551 T DE69203551 T DE 69203551T DE 69203551 T2 DE69203551 T2 DE 69203551T2
Authority
DE
Germany
Prior art keywords
hydroxyproline
pharmaceutical composition
composition containing
biodegradable copolyester
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69203551T
Other languages
English (en)
Other versions
DE69203551D1 (de
Inventor
Seiji Mochizuki
Kiyoshi Nawata
Yuji Makino
Yoshiki Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of DE69203551D1 publication Critical patent/DE69203551D1/de
Application granted granted Critical
Publication of DE69203551T2 publication Critical patent/DE69203551T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
    • C08G63/685—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen
    • C08G63/6852—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen derived from hydroxy carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Pyrrole Compounds (AREA)
DE69203551T 1991-09-06 1992-09-01 Biologisch abbaubarer Copolyester von 4-Hydroxyprolin und diesen enthaltende pharmazeutische Zusammensetzung. Expired - Fee Related DE69203551T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP25429091 1991-09-06

Publications (2)

Publication Number Publication Date
DE69203551D1 DE69203551D1 (de) 1995-08-24
DE69203551T2 true DE69203551T2 (de) 1996-01-11

Family

ID=17262915

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69203551T Expired - Fee Related DE69203551T2 (de) 1991-09-06 1992-09-01 Biologisch abbaubarer Copolyester von 4-Hydroxyprolin und diesen enthaltende pharmazeutische Zusammensetzung.

Country Status (7)

Country Link
US (1) US5395916A (de)
EP (1) EP0531091B1 (de)
JP (1) JPH05202177A (de)
AT (1) ATE125278T1 (de)
DE (1) DE69203551T2 (de)
DK (1) DK0531091T3 (de)
ES (1) ES2074828T3 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6372880B1 (en) 1997-12-25 2002-04-16 Mitsui Chemicals, Inc. Copolymer and process for preparing the same
AU6510400A (en) * 1999-08-04 2001-03-05 Oakwood Laboratories L.L.C. Slow release microspheres
US7265247B1 (en) 2006-07-28 2007-09-04 Im&T Research, Inc. Substituted phenylsulfur trifluoride and other like fluorinating agents
KR101421920B1 (ko) * 2007-03-23 2014-07-22 우베 인더스트리즈 리미티드 아릴설퍼 펜타플루오라이드의 제조공정
US8399720B2 (en) * 2007-03-23 2013-03-19 Ube Industries, Ltd. Methods for producing fluorinated phenylsulfur pentafluorides
US8030516B2 (en) * 2007-10-19 2011-10-04 Ube Industries, Ltd. Methods for producing perfluoroalkanedi(sulfonyl chloride)
WO2009076345A1 (en) * 2007-12-11 2009-06-18 Im & T Research, Inc. Methods and compositions for producing difluoromethylene-and trifluoromethyl-containing compounds
TW201006787A (en) * 2008-03-07 2010-02-16 Im & T Res Inc Fluorination processes with arylsulfur halotetrafluorides
WO2010022001A1 (en) * 2008-08-18 2010-02-25 Im&T Research, Inc. Methods for preparing fluoroalkyl arylsulfinyl compounds and fluorinated compounds thereto
US8653302B2 (en) * 2008-09-22 2014-02-18 Ube Industries, Ltd. Processes for preparing poly(pentafluorosulfanyl)aromatic compounds
US20100174096A1 (en) * 2009-01-05 2010-07-08 Im&T Research, Inc. Methods for Production of Optically Active Fluoropyrrolidine Derivatives
WO2010081014A1 (en) * 2009-01-09 2010-07-15 Im&T Research, Inc. Novel 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093709A (en) * 1975-01-28 1978-06-06 Alza Corporation Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates)
USRE30170E (en) * 1975-04-04 1979-12-18 Sutures, Inc. Hydrolyzable polymers of amino acid and hydroxy acids
US4428939A (en) * 1981-10-16 1984-01-31 Prockop Darwin J Collagen inhibiting compositions and processes for manufacturing and using same
JPS61172813A (ja) * 1985-01-28 1986-08-04 Japan Atom Energy Res Inst ポリ乳酸を担体とする徐放性複合体の製造方法
JPH0720859B2 (ja) * 1985-02-07 1995-03-08 武田薬品工業株式会社 マイクロカプセルの製造法
US4831107A (en) * 1986-07-28 1989-05-16 Semih Erhan Polymer preparation from lysine and a quinone
JPS6341416A (ja) * 1986-08-08 1988-02-22 Takeda Chem Ind Ltd 鎮痛性ペプチド含有マイクロカプセルの製造法
JP2702729B2 (ja) * 1988-02-24 1998-01-26 エーザイ株式会社 徐放性埋込剤
CA2046830C (en) * 1990-07-19 1999-12-14 Patrick P. Deluca Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer

Also Published As

Publication number Publication date
DE69203551D1 (de) 1995-08-24
ES2074828T3 (es) 1995-09-16
DK0531091T3 (da) 1995-09-11
US5395916A (en) 1995-03-07
EP0531091A1 (de) 1993-03-10
ATE125278T1 (de) 1995-08-15
JPH05202177A (ja) 1993-08-10
EP0531091B1 (de) 1995-07-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee