SE7407913L - - Google Patents
Info
- Publication number
- SE7407913L SE7407913L SE7407913A SE7407913A SE7407913L SE 7407913 L SE7407913 L SE 7407913L SE 7407913 A SE7407913 A SE 7407913A SE 7407913 A SE7407913 A SE 7407913A SE 7407913 L SE7407913 L SE 7407913L
- Authority
- SE
- Sweden
- Prior art keywords
- groups
- carbon atoms
- atom
- oxoalkyl
- carbon atom
- Prior art date
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 229910052799 carbon Inorganic materials 0.000 abstract 4
- 125000005188 oxoalkyl group Chemical group 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2330742A DE2330742C2 (de) | 1973-06-16 | 1973-06-16 | 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7407913L true SE7407913L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-12-17 |
| SE423631B SE423631B (sv) | 1982-05-17 |
Family
ID=5884209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7407913A SE423631B (sv) | 1973-06-16 | 1974-06-14 | Forfarande for framstellning av oxaalhyl-dialkylxantiner |
Country Status (17)
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH608236A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1974-01-22 | 1978-12-29 | Wuelfing J A Fa | |
| DE2507554A1 (de) * | 1975-02-21 | 1976-09-02 | Wuelfing J A Fa | 7-(oxoalkyl)-1,3-dialkylxanthine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE2507555A1 (de) * | 1975-02-21 | 1976-09-02 | Wuelfing J A Fa | 7-(oxoalkyl)-1,3-dialkylxanthine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel |
| JPS54112893A (en) * | 1978-02-21 | 1979-09-04 | Kohjin Co Ltd | Preparation of 1-(5'-oxohexyl)-3,7-diethylxanthine |
| DE2967632D1 (en) * | 1978-04-22 | 1986-12-04 | Beecham Wuelfing Gmbh & Co Kg | Use of a xanthine derivate in the manufacture of a medicament |
| IL59665A0 (en) * | 1979-04-05 | 1980-06-30 | Wuelfing J Kg | Xanthine derivatives,process for their preparation and their use in pharmaceutical compositions |
| EP0157098A1 (en) * | 1980-06-21 | 1985-10-09 | Beecham Wuelfing GmbH & Co KG | Xanthine derivatives, pharmaceuticals compositions containing them and a process for their preparation |
| US4636507A (en) * | 1984-04-30 | 1987-01-13 | Hoechst-Roussel Pharmaceuticals Inc. | Host defense mechanism enhancement |
| JPH062675B2 (ja) * | 1985-04-05 | 1994-01-12 | ヘキストジヤパン株式会社 | 記憶障害治療剤 |
| GB8621869D0 (en) * | 1986-09-11 | 1986-10-15 | Beecham Group Plc | Treatment |
| JPS63225317A (ja) * | 1986-10-06 | 1988-09-20 | Hoechst Japan Kk | 抗消化性潰瘍剤 |
| IT1197516B (it) * | 1986-12-24 | 1988-11-30 | Abc Ist Biolog Chem Spa | Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono |
| US5096906A (en) * | 1986-12-31 | 1992-03-17 | University Of Virginia Alumni Patents Foundation | Method of inhibiting the activity of leukocyte derived cytokines |
| US4965271A (en) * | 1986-12-31 | 1990-10-23 | Hoechst Roussel Pharmaceuticals, Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
| CA2030112A1 (en) * | 1989-11-24 | 1991-05-25 | Yasuo Ito | Xanthine compound, method for preparing thereof, and a pharmaceutical composition comprising the same |
| DE3942872A1 (de) * | 1989-12-23 | 1991-06-27 | Hoechst Ag | Verfahren zur enantioselektiven darstellung von ((omega)-1)-hydroxyalkylxanthinen |
| US6420374B1 (en) | 1990-11-30 | 2002-07-16 | Fred Hutchinson Cancer Research Center | Use of xanthines as immunosuppressants and to inhibit allograft reactions |
| DE59207086D1 (de) * | 1991-05-23 | 1996-10-17 | Hoechst Ag | Die Verwendung von 1-(5-Oxohexyl)-3-methyl-7-n-propyl-xanthin in der Gefässchirurgie |
| MX9203323A (es) * | 1991-07-11 | 1994-07-29 | Hoechst Ag | El empleo de derivados de xantina para el tratamiento de lesiones secundarias de las celulas nerviosas y trastornos funcionales despues de traumas craneo-cerebrales. |
| JP2549480B2 (ja) * | 1991-12-10 | 1996-10-30 | ヘキストジャパン株式会社 | 排尿障害改善剤 |
| EP0570831A2 (de) * | 1992-05-20 | 1993-11-24 | Hoechst Aktiengesellschaft | Verwendung von Xanthinderivaten zur Behandlung von Nervenschädigungen nach Unterbrechung der Blutzirkulation |
| US6020337A (en) * | 1993-04-05 | 2000-02-01 | Cell Therapeutics, Inc. | Electronegative-substituted long chain xanthine compounds |
| US5670506A (en) * | 1993-04-05 | 1997-09-23 | Cell Therapeutics, Inc. | Halogen, isothiocyanate or azide substituted xanthines |
| AU1868195A (en) * | 1994-01-28 | 1995-08-15 | Cell Therapeutics, Inc. | Cell signaling inhibitors |
| US5762953A (en) * | 1996-08-22 | 1998-06-09 | Theratech, Inc. | Transdermal propentofylline compositions for the treatment of Alzheimers disease |
| DE19707655A1 (de) * | 1997-02-26 | 1998-08-27 | Hoechst Ag | Kombinationspräparat zur Anwendung bei Demenz |
| US20040110776A1 (en) * | 2002-02-22 | 2004-06-10 | Iok-Hou Pang | Use of propentofylline to control intraocular pressure |
| BRPI0908107A2 (pt) | 2008-02-29 | 2019-09-24 | Concert Pharmaceuticals Inc | composto derivado de xantina substituída, composição farmacêutica que compreende esse composto, métodos de tratamento de uma enfermidade ou condição em um paciente com necessidade do mesmo, método de tratamento de enfermidade crônica dos rins, do fígado, relacionada com diabetes e de claudicação intermitente |
| US20110053961A1 (en) | 2009-02-27 | 2011-03-03 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
| AU2010289551A1 (en) | 2009-09-02 | 2012-03-01 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
| EP3397640B1 (en) * | 2015-12-29 | 2021-08-04 | INSERM - Institut National de la Santé et de la Recherche Médicale | Xanthine derivative inhibitors of bet proteins |
| CN112724160A (zh) * | 2021-03-19 | 2021-04-30 | 赤峰经方医药技术开发有限责任公司 | 一种己酮可可碱杂质的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH325292A (de) * | 1953-10-21 | 1957-10-31 | Geigy Ag J R | Verfahren zur Herstellung von 7-Oxyalkyl-xanthinderivaten |
| FR1211333A (fr) * | 1955-10-19 | 1960-03-15 | Boehringer Sohn Ingelheim | Perfectionnements apportés aux procédés pour fabriquer des oxyalcoylxanthines |
| US3422107A (en) | 1964-09-05 | 1969-01-14 | Albert Ag Chem Werke | Certain oxoalkyldimethylxanthines and a process for the preparation thereof |
| US3737433A (en) | 1964-09-05 | 1973-06-05 | Albert Ag Chem Werke | Certain oxoalkyldimethylxanthines |
| DE1233405B (de) | 1964-09-05 | 1967-02-02 | Albert Ag Chem Werke | Verfahren zur Herstellung von 7-(Oxoalkyl)-1, 3-dimethylxanthinen |
| DE1235320B (de) * | 1964-09-05 | 1967-03-02 | Albert Ag Chem Werke | Verfahren zur Herstellung von 1-(Oxoalkyl)-3, 7-dimethylxanthinen |
| US3864469A (en) * | 1967-12-16 | 1975-02-04 | Hoechst Ag | Xanthines in pharmaceutical preparations and for stabilization of vitamins |
| DE1810705C3 (de) * | 1968-11-25 | 1980-11-27 | Hoechst Ag, 6000 Frankfurt | Stabilisierung von Vitaminen |
| DE1911279A1 (de) * | 1969-03-05 | 1970-11-12 | Eckert Dr Theodor | Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen |
-
1973
- 1973-06-16 DE DE2330742A patent/DE2330742C2/de not_active Expired
-
1974
- 1974-01-01 AR AR254209A patent/AR208179A1/es active
- 1974-06-11 NO NO742121A patent/NO140300C/no unknown
- 1974-06-11 ES ES427171A patent/ES427171A1/es not_active Expired
- 1974-06-12 ZA ZA00743760A patent/ZA743760B/xx unknown
- 1974-06-13 NL NLAANVRAGE7407890,A patent/NL182806C/xx not_active IP Right Cessation
- 1974-06-14 SE SE7407913A patent/SE423631B/xx not_active IP Right Cessation
- 1974-06-14 GB GB2655574A patent/GB1470220A/en not_active Expired
- 1974-06-14 BE BE145417A patent/BE816332A/xx not_active IP Right Cessation
- 1974-06-14 FR FR7420679A patent/FR2233065B1/fr not_active Expired
- 1974-06-14 CH CH123978A patent/CH612969A5/xx not_active IP Right Cessation
- 1974-06-14 DK DK321574A patent/DK145676C/da active
- 1974-06-14 FI FI1819/74A patent/FI58920C/fi active
- 1974-06-14 JP JP49067265A patent/JPS5233120B2/ja not_active Expired
- 1974-06-14 AT AT491874A patent/AT334388B/de not_active IP Right Cessation
- 1974-06-14 IE IE1258/74A patent/IE39898B1/xx unknown
- 1974-06-14 CH CH748211A patent/CH608807A5/xx not_active IP Right Cessation
-
1975
- 1975-08-22 AR AR260112A patent/AR209319A1/es active
- 1975-08-22 AR AR260113A patent/AR209320A1/es active
-
1979
- 1979-04-23 US US06/032,536 patent/US4289776A/en not_active Expired - Lifetime
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7407913-8 Effective date: 19940710 Format of ref document f/p: F |