ES8502962A1 - Un procedimiento para preparar un derivado de acido bifenililpropionico - Google Patents

Un procedimiento para preparar un derivado de acido bifenililpropionico

Info

Publication number
ES8502962A1
ES8502962A1 ES525498A ES525498A ES8502962A1 ES 8502962 A1 ES8502962 A1 ES 8502962A1 ES 525498 A ES525498 A ES 525498A ES 525498 A ES525498 A ES 525498A ES 8502962 A1 ES8502962 A1 ES 8502962A1
Authority
ES
Spain
Prior art keywords
same
carbon atoms
alkyl group
preparing
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES525498A
Other languages
English (en)
Other versions
ES525498A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP15857882A external-priority patent/JPS5948445A/ja
Priority claimed from JP58026559A external-priority patent/JPS59152348A/ja
Priority claimed from JP10151983A external-priority patent/JPS59225143A/ja
Application filed by Kaken Pharmaceutical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Publication of ES8502962A1 publication Critical patent/ES8502962A1/es
Publication of ES525498A0 publication Critical patent/ES525498A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE ACIDO BIFENILILPROPIONICO.COMPRENDE HACER REACCIONAR ACIDO 2-(2-FLUORO-4-BIFENIL) PROPIONICO O UNA SAL DEL MISMO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III) O CON UN COMPUESTO DE FORMULA (IV) PARA OBTENER UN DERIVADO DE ACIDO BIFENILILPROPIONICO DE FORMULA (I) DONDE R ES ALQUILCARBONILOXIALQUILO O UN GRUPO ALQUENILCARBONILOXIALQUILO DE FORMULA (V) DONDE R ES UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO INFERIOR CON C 1 A 5; R ES UN GRUPO ALQUILO CON C 1 A 15 O UN GRUPO ALQUENILO CON C 2 A 8 Y M ES 0 O 1.TIENE APLICACIONES FARMACEUTICAS POR POSEER PROPIEDADES ANALGESICAS, ANTIINFLAMATORIAS Y ANTIPIRETICAS.
ES525498A 1982-09-10 1983-09-08 Un procedimiento para preparar un derivado de acido bifenililpropionico Granted ES525498A0 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15857882A JPS5948445A (ja) 1982-09-10 1982-09-10 ビフエニリルプロピオン酸誘導体およびその製造法
JP58026559A JPS59152348A (ja) 1983-02-19 1983-02-19 ビフエニリルプロピオン酸エステル誘導体およびその製造法
JP10151983A JPS59225143A (ja) 1983-06-06 1983-06-06 ビフエニリルプロピオン酸誘導体およびその製造法

Publications (2)

Publication Number Publication Date
ES8502962A1 true ES8502962A1 (es) 1985-02-01
ES525498A0 ES525498A0 (es) 1985-02-01

Family

ID=27285454

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525498A Granted ES525498A0 (es) 1982-09-10 1983-09-08 Un procedimiento para preparar un derivado de acido bifenililpropionico

Country Status (5)

Country Link
EP (1) EP0103265B1 (es)
AU (1) AU559633B2 (es)
DE (1) DE3368046D1 (es)
ES (1) ES525498A0 (es)
NZ (1) NZ205516A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196567A (en) * 1983-02-19 1993-03-23 Kaken Pharmaceutical Co., Ltd. Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same
JPS601122A (ja) * 1983-06-20 1985-01-07 Green Cross Corp:The ビフエニリルプロピオン酸誘導体脂肪乳剤
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1359987A (en) * 1970-10-12 1974-07-17 Boots Co Ltd 2-substituted biphenylyl propionic acids
EP0032620B2 (en) * 1979-12-19 1987-02-04 The Upjohn Company Process for preparing therapeutic 2-arylpropionic acids and esters, and novel arylmethylmalonate esters

Also Published As

Publication number Publication date
EP0103265A2 (en) 1984-03-21
EP0103265B1 (en) 1986-12-03
EP0103265A3 (en) 1984-07-25
ES525498A0 (es) 1985-02-01
AU1877283A (en) 1984-03-15
AU559633B2 (en) 1987-03-19
DE3368046D1 (en) 1987-01-15
NZ205516A (en) 1986-01-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010402