ES8600232A1 - Procedimiento para preparar bencenos sustituidos. - Google Patents

Procedimiento para preparar bencenos sustituidos.

Info

Publication number
ES8600232A1
ES8600232A1 ES523333A ES523333A ES8600232A1 ES 8600232 A1 ES8600232 A1 ES 8600232A1 ES 523333 A ES523333 A ES 523333A ES 523333 A ES523333 A ES 523333A ES 8600232 A1 ES8600232 A1 ES 8600232A1
Authority
ES
Spain
Prior art keywords
alkyl
benzenes
mercapto
oxy
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523333A
Other languages
English (en)
Other versions
ES523333A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES523333A0 publication Critical patent/ES523333A0/es
Publication of ES8600232A1 publication Critical patent/ES8600232A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

PROCEDIMIENTO PARA PREPARAR BENCENOS SUSTITUIDOS.COMPRENDE: HIDROLIZAR, POR HIDROLISIS ALCALINA, EN UN MEDIO ACUOSO O ALCOLICO ACUOSO, A UNA TEMPERATURA ENTRE 15JC Y LA TEMPERATURA DE REFLUJO, UN COMPUESTO DE FORMULA (II) EN LA QUE, O BIEN, X ES F S Y Z ES -OR5 EN DONDE R5 ES C 1 A 4 O X ES F NH Y Z ES -NH2, PARA PREPARAR UN COMPUESTO DE FORMULA (I) EN LA QUE R3 ES H; Y OPCIONALMENTE ACILAR EL COMPUESTO DE FORMULA (I) EN LA QUE R2 Y/O R3 ES (N) UN ATOMO DE H, EN PRESENCIA DE UN DISOLVENTE O DILUYENTE INERTE, A UNA TEMPERATURA ENTRE 15 Y 50JC; Y/O SOMETER A S-S-DIMERIZACION UN COMPUESTO DE FORMULA (I) A LA QUE R3 ES H, POR OXIDACION, EN PRESENCIA DE OXIGENO ATMOSFERICO Y EN UN MEDIO ALCALINO, A UNA TEMPERATURA DE 15 A 50JC, PARA OBTENER UN COMPUESTO DE FORMULA (I) EN LA QUE R3 ES UN GRUPO DE FORMULA (A), R, R1 Y R2 SON H O ALQUILO DE C 1 A 6, Y A ES UN RADICAL ALQUILENO DE CADENA RECTA.SE UTILIZA COMO AGENTES ANALGESICOS Y/O ANTIPIRETICOS.
ES523333A 1982-06-17 1983-06-16 Procedimiento para preparar bencenos sustituidos. Expired ES8600232A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH374682 1982-06-17

Publications (2)

Publication Number Publication Date
ES523333A0 ES523333A0 (es) 1985-10-01
ES8600232A1 true ES8600232A1 (es) 1985-10-01

Family

ID=4262594

Family Applications (1)

Application Number Title Priority Date Filing Date
ES523333A Expired ES8600232A1 (es) 1982-06-17 1983-06-16 Procedimiento para preparar bencenos sustituidos.

Country Status (16)

Country Link
JP (1) JPS5916872A (es)
AU (1) AU1585283A (es)
BE (1) BE897034A (es)
DE (1) DE3320746A1 (es)
DK (1) DK279383A (es)
ES (1) ES8600232A1 (es)
FI (1) FI832097L (es)
FR (1) FR2528832B1 (es)
GB (1) GB2121800B (es)
IL (1) IL68974A0 (es)
IT (1) IT1197665B (es)
NL (1) NL8302108A (es)
PT (1) PT76877B (es)
SE (1) SE8303410L (es)
WO (1) WO1984000032A1 (es)
ZA (1) ZA834471B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743585A (en) * 1986-11-21 1988-05-10 Warner-Lambert Company Renin inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH442313A (de) * 1963-03-18 1967-08-31 Hoffmann La Roche Verfahren zur Herstellung von heterocyclischen Verbindungen

Also Published As

Publication number Publication date
DK279383D0 (da) 1983-06-16
AU1585283A (en) 1983-12-22
IT1197665B (it) 1988-12-06
IL68974A0 (en) 1983-10-31
ES523333A0 (es) 1985-10-01
DE3320746A1 (de) 1983-12-22
FI832097L (fi) 1983-12-18
JPS5916872A (ja) 1984-01-28
GB2121800A (en) 1984-01-04
SE8303410L (sv) 1983-12-18
FI832097A0 (fi) 1983-06-10
GB8316053D0 (en) 1983-07-20
FR2528832A1 (fr) 1983-12-23
WO1984000032A1 (en) 1984-01-05
SE8303410D0 (sv) 1983-06-15
DK279383A (da) 1983-12-18
PT76877B (en) 1986-03-11
BE897034A (fr) 1983-12-13
PT76877A (en) 1983-07-01
GB2121800B (en) 1985-09-11
FR2528832B1 (fr) 1985-10-25
NL8302108A (nl) 1984-01-16
IT8348521A0 (it) 1983-06-16
ZA834471B (en) 1985-02-27

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