SE501389C2 - Farmaceutiskt preparat och förfarande för dess framställning - Google Patents

Farmaceutiskt preparat och förfarande för dess framställning

Info

Publication number
SE501389C2
SE501389C2 SE9201299A SE9201299A SE501389C2 SE 501389 C2 SE501389 C2 SE 501389C2 SE 9201299 A SE9201299 A SE 9201299A SE 9201299 A SE9201299 A SE 9201299A SE 501389 C2 SE501389 C2 SE 501389C2
Authority
SE
Sweden
Prior art keywords
preparation
film
tablet
dissolves
clodronate
Prior art date
Application number
SE9201299A
Other languages
English (en)
Swedish (sv)
Other versions
SE9201299D0 (sv
SE9201299L (sv
Inventor
Juhani Posti
Kirsi Katila
Pertti Rantala
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Priority to SE9201299A priority Critical patent/SE501389C2/sv
Publication of SE9201299D0 publication Critical patent/SE9201299D0/xx
Priority to TW082102782A priority patent/TW273515B/zh
Priority to IL105403A priority patent/IL105403A/en
Priority to CZ942614A priority patent/CZ282871B6/cs
Priority to US08/318,650 priority patent/US5525354A/en
Priority to DE0637236T priority patent/DE637236T1/de
Priority to HU9403067A priority patent/HU219342B/hu
Priority to AU39550/93A priority patent/AU671830B2/en
Priority to PCT/FI1993/000166 priority patent/WO1993021907A1/en
Priority to RU94045950A priority patent/RU2116074C1/ru
Priority to CA002134196A priority patent/CA2134196C/en
Priority to DE69305335T priority patent/DE69305335T2/de
Priority to DK93908973.6T priority patent/DK0637236T3/da
Priority to JP51895893A priority patent/JP3536106B2/ja
Priority to AT93908973T priority patent/ATE143802T1/de
Priority to EP93908973A priority patent/EP0637236B1/en
Priority to ES93908973T priority patent/ES2094539T3/es
Publication of SE9201299L publication Critical patent/SE9201299L/xx
Priority to NO944001A priority patent/NO306654B1/no
Priority to FI944961A priority patent/FI110667B/fi
Priority to EE9400134A priority patent/EE03107B1/xx
Publication of SE501389C2 publication Critical patent/SE501389C2/sv
Priority to GR970400013T priority patent/GR3022249T3/el
Priority to HK13097A priority patent/HK13097A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SE9201299A 1992-04-24 1992-04-24 Farmaceutiskt preparat och förfarande för dess framställning SE501389C2 (sv)

Priority Applications (22)

Application Number Priority Date Filing Date Title
SE9201299A SE501389C2 (sv) 1992-04-24 1992-04-24 Farmaceutiskt preparat och förfarande för dess framställning
TW082102782A TW273515B (no) 1992-04-24 1993-04-13
IL105403A IL105403A (en) 1992-04-24 1993-04-15 Pharmaceutical preparation containing dichloromethylene bisphosphonic acid and process for its manufacture
ES93908973T ES2094539T3 (es) 1992-04-24 1993-04-21 Preparacion farmaceutica y procedimiento para su preparacion.
CA002134196A CA2134196C (en) 1992-04-24 1993-04-21 Pharmaceutical preparation and process for its manufacture
AT93908973T ATE143802T1 (de) 1992-04-24 1993-04-21 Pharmazeutische zubereitung und verfahren für ihre herstellung
DE0637236T DE637236T1 (de) 1992-04-24 1993-04-21 Pharmazeutische zubereitung und verfahren für ihre herstellung.
HU9403067A HU219342B (en) 1992-04-24 1993-04-21 Oral pharmaceutical preparation comprising clodronate as active ingredient and process for its manufacture
AU39550/93A AU671830B2 (en) 1992-04-24 1993-04-21 A Pharmaceutical Preparation of Dichloromethylene Bisphosphonic Acid with Enteric Coating for Oral Use
PCT/FI1993/000166 WO1993021907A1 (en) 1992-04-24 1993-04-21 Pharmaceutical preparation and process for its manufacture
RU94045950A RU2116074C1 (ru) 1992-04-24 1993-04-21 Фармацевтический препарат и способ его приготовления
CZ942614A CZ282871B6 (cs) 1992-04-24 1993-04-21 Farmaceutický přípravek pro orální použití a způsob jeho výroby
DE69305335T DE69305335T2 (de) 1992-04-24 1993-04-21 Pharmazeutische zubereitung und verfahren für ihre herstellung
DK93908973.6T DK0637236T3 (da) 1992-04-24 1993-04-21 Farmaceutisk præparat og fremgangsmåde til dets fremstilling
JP51895893A JP3536106B2 (ja) 1992-04-24 1993-04-21 製剤及びその製造方法
US08/318,650 US5525354A (en) 1992-04-24 1993-04-21 Pharmaceutical preparation and process for its manufacture
EP93908973A EP0637236B1 (en) 1992-04-24 1993-04-21 Pharmaceutical preparation and process for its manufacture
FI944961A FI110667B (fi) 1992-04-24 1994-10-21 Menetelmä farmaseuttisen valmisteen valmistamiseksi
NO944001A NO306654B1 (no) 1992-04-24 1994-10-21 Farmasöytisk preparat inneholdende diklormetylenbisfosfonsyre eller salt derav for oral tilförsel
EE9400134A EE03107B1 (et) 1992-04-24 1994-11-15 Ravimpreparaat ja meetod selle valmistamiseks
GR970400013T GR3022249T3 (en) 1992-04-24 1997-01-09 Pharmaceutical preparation and process for its manufacture.
HK13097A HK13097A (en) 1992-04-24 1997-02-05 Pharmaceutical preparation and process for its manufacture

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9201299A SE501389C2 (sv) 1992-04-24 1992-04-24 Farmaceutiskt preparat och förfarande för dess framställning

Publications (3)

Publication Number Publication Date
SE9201299D0 SE9201299D0 (sv) 1992-04-24
SE9201299L SE9201299L (sv) 1993-10-25
SE501389C2 true SE501389C2 (sv) 1995-01-30

Family

ID=20386054

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9201299A SE501389C2 (sv) 1992-04-24 1992-04-24 Farmaceutiskt preparat och förfarande för dess framställning

Country Status (21)

Country Link
US (1) US5525354A (no)
EP (1) EP0637236B1 (no)
JP (1) JP3536106B2 (no)
AT (1) ATE143802T1 (no)
AU (1) AU671830B2 (no)
CA (1) CA2134196C (no)
CZ (1) CZ282871B6 (no)
DE (2) DE69305335T2 (no)
DK (1) DK0637236T3 (no)
EE (1) EE03107B1 (no)
ES (1) ES2094539T3 (no)
FI (1) FI110667B (no)
GR (1) GR3022249T3 (no)
HK (1) HK13097A (no)
HU (1) HU219342B (no)
IL (1) IL105403A (no)
NO (1) NO306654B1 (no)
RU (1) RU2116074C1 (no)
SE (1) SE501389C2 (no)
TW (1) TW273515B (no)
WO (1) WO1993021907A1 (no)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6406714B1 (en) 1992-12-02 2002-06-18 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids
HU220872B1 (en) 1993-05-15 2002-06-29 Roche Diagnostics Gmbh Tablets containing dichloromethylene diphosphonic acid as active agent with enhanced bioavailability and process for producing them
US5431920A (en) * 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
FI94926C (fi) * 1993-11-12 1995-11-27 Leiras Oy Menetelmä klodronaattivalmisteen valmistamiseksi
US20010007863A1 (en) 1998-06-18 2001-07-12 Merck & Co., Inc. Wet granulation formulation for bisphosphonic acids
TW390813B (en) * 1994-04-29 2000-05-21 Merck & Co Inc Wet granulation formulation for bisphosphonic acids
FI98343C (fi) * 1995-03-21 1997-06-10 Orion Yhtymae Oy Peroraalinen formulaatio
DE19719680A1 (de) 1997-05-09 1998-11-19 Boehringer Mannheim Gmbh Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
JPH11137208A (ja) * 1997-11-14 1999-05-25 Nikken Chem Co Ltd 口腔内速溶性固形物及びその製造方法
EP0998933A1 (de) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Verfahren zur Herstellung von bisphosphonathaltigen pharmazeutischen Zusammensetzungen zur oralen Applikation
EP0998932A1 (de) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung
US7658938B2 (en) 1999-02-22 2010-02-09 Merrion Reasearch III Limited Solid oral dosage form containing an enhancer
EP1154761B1 (en) * 1999-02-22 2008-02-20 Merrion Research I Limited Solid oral dosage form containing an enhancer
SE9901272D0 (sv) * 1999-04-09 1999-04-09 Astra Ab New improved formulation
US6562974B2 (en) 2000-02-01 2003-05-13 The Procter & Gamble Company Process for making geminal bisphosphonates
US6410520B2 (en) 2000-02-01 2002-06-25 The Procter & Gamble Company Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate
JP4489356B2 (ja) 2001-05-11 2010-06-23 メリオン リサーチ スリー リミテッド 浸透促進剤
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
US20080286359A1 (en) 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
US7645460B2 (en) 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of risedronate
US7645459B2 (en) 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of bisphosphonates
US20080287400A1 (en) 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
MX2008012678A (es) 2006-04-07 2008-12-17 Merrion Res Iii Ltd Forma de dosis oral solida que contiene un mejorador.
KR20110007242A (ko) 2008-05-07 2011-01-21 메리온 리서치 Ⅲ 리미티드 펩티드 조성물 및 그의 제조 방법
DE102008022520A1 (de) * 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
US9089484B2 (en) 2010-03-26 2015-07-28 Merrion Research Iii Limited Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
CN103476419A (zh) 2011-01-07 2013-12-25 梅里翁第三研究有限公司 口服投药的含铁药物组合物
ES2975708T3 (es) 2015-01-29 2024-07-12 Novo Nordisk As Comprimidos que comprenden agonista del GLP-1 y recubrimiento entérico

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
DE3767998D1 (de) * 1986-12-20 1991-03-14 Boehringer Mannheim Gmbh Clodronat-haltige arzneimittel und verfahren zur herstellung derselben.
JP2782691B2 (ja) * 1987-09-29 1998-08-06 ワーナー−ランバート・コンパニー 腸溶製剤の安定化
FR2629716B1 (fr) * 1988-04-07 1991-07-19 Sanofi Sa Composition pharmaceutique pour administration orale a base d'un derive d'acide diphosphonique

Also Published As

Publication number Publication date
FI110667B (fi) 2003-03-14
HK13097A (en) 1997-02-14
WO1993021907A1 (en) 1993-11-11
FI944961A0 (fi) 1994-10-21
EE03107B1 (et) 1998-08-17
HU9403067D0 (en) 1994-12-28
EP0637236B1 (en) 1996-10-09
CA2134196C (en) 2004-02-10
IL105403A (en) 1998-03-10
HUT74572A (en) 1997-01-28
SE9201299D0 (sv) 1992-04-24
FI944961A (fi) 1994-10-21
JP3536106B2 (ja) 2004-06-07
HU219342B (en) 2001-03-28
TW273515B (no) 1996-04-01
US5525354A (en) 1996-06-11
CZ282871B6 (cs) 1997-11-12
ES2094539T3 (es) 1997-01-16
SE9201299L (sv) 1993-10-25
ATE143802T1 (de) 1996-10-15
JPH07505898A (ja) 1995-06-29
DE637236T1 (de) 1995-07-06
RU94045950A (ru) 1996-11-10
DE69305335D1 (de) 1996-11-14
CA2134196A1 (en) 1993-11-11
GR3022249T3 (en) 1997-04-30
RU2116074C1 (ru) 1998-07-27
AU671830B2 (en) 1996-09-12
NO944001L (no) 1994-10-21
IL105403A0 (en) 1993-08-18
EP0637236A1 (en) 1995-02-08
NO944001D0 (no) 1994-10-21
DE69305335T2 (de) 1997-04-30
NO306654B1 (no) 1999-12-06
AU3955093A (en) 1993-11-29
DK0637236T3 (da) 1997-03-17
CZ261494A3 (en) 1995-02-15

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