SE466791B - Kolonnfyllningsmaterial och anvaendning av detta foer vaetskekromatografi och blodbehandling - Google Patents
Kolonnfyllningsmaterial och anvaendning av detta foer vaetskekromatografi och blodbehandlingInfo
- Publication number
- SE466791B SE466791B SE8702761A SE8702761A SE466791B SE 466791 B SE466791 B SE 466791B SE 8702761 A SE8702761 A SE 8702761A SE 8702761 A SE8702761 A SE 8702761A SE 466791 B SE466791 B SE 466791B
- Authority
- SE
- Sweden
- Prior art keywords
- filling material
- coating
- calcium phosphate
- particles
- hydroxyapatite
- Prior art date
Links
- 239000000463 material Substances 0.000 title claims description 32
- 238000011049 filling Methods 0.000 title claims description 18
- 239000008280 blood Substances 0.000 title claims 2
- 210000004369 blood Anatomy 0.000 title claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 24
- 239000011248 coating agent Substances 0.000 claims description 18
- 238000000576 coating method Methods 0.000 claims description 18
- 239000001506 calcium phosphate Substances 0.000 claims description 16
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 16
- 235000011010 calcium phosphates Nutrition 0.000 claims description 16
- 239000000758 substrate Substances 0.000 claims description 16
- 150000001875 compounds Chemical class 0.000 claims description 15
- 239000002245 particle Substances 0.000 claims description 14
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 14
- 239000000377 silicon dioxide Substances 0.000 claims description 12
- 239000011575 calcium Substances 0.000 claims description 5
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 4
- 238000004811 liquid chromatography Methods 0.000 claims description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- 239000004793 Polystyrene Substances 0.000 claims description 3
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- 229920002223 polystyrene Polymers 0.000 claims description 3
- 229910019142 PO4 Inorganic materials 0.000 claims description 2
- 239000005365 phosphate glass Substances 0.000 claims description 2
- 229920000728 polyester Polymers 0.000 claims description 2
- 239000011324 bead Substances 0.000 description 15
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 14
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 14
- 238000004544 sputter deposition Methods 0.000 description 10
- 102000016943 Muramidase Human genes 0.000 description 8
- 108010014251 Muramidase Proteins 0.000 description 8
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 description 8
- 239000000945 filler Substances 0.000 description 8
- 239000008187 granular material Substances 0.000 description 8
- 229960000274 lysozyme Drugs 0.000 description 8
- 235000010335 lysozyme Nutrition 0.000 description 8
- 239000004325 lysozyme Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 238000004458 analytical method Methods 0.000 description 5
- 239000000523 sample Substances 0.000 description 5
- 101000693922 Bos taurus Albumin Proteins 0.000 description 4
- 102000018832 Cytochromes Human genes 0.000 description 4
- 108010052832 Cytochromes Proteins 0.000 description 4
- 238000005054 agglomeration Methods 0.000 description 4
- 230000002776 aggregation Effects 0.000 description 4
- 239000012300 argon atmosphere Substances 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 239000002002 slurry Substances 0.000 description 4
- 239000012064 sodium phosphate buffer Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- -1 phosphoric acid compound Chemical class 0.000 description 3
- 238000005086 pumping Methods 0.000 description 3
- 238000005096 rolling process Methods 0.000 description 3
- 238000001694 spray drying Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 229940043430 calcium compound Drugs 0.000 description 1
- 150000001674 calcium compounds Chemical class 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 229910052593 corundum Inorganic materials 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N phosphoric acid Substances OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000012798 spherical particle Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 229910001845 yogo sapphire Inorganic materials 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/282—Porous sorbents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
- B01J20/04—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium
- B01J20/048—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium containing phosphorus, e.g. phosphates, apatites, hydroxyapatites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
- B01J20/28016—Particle form
- B01J20/28019—Spherical, ellipsoidal or cylindrical
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3234—Inorganic material layers
- B01J20/3236—Inorganic material layers containing metal, other than zeolites, e.g. oxides, hydroxides, sulphides or salts
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61158412A JPH07104332B2 (ja) | 1986-07-05 | 1986-07-05 | カラム用充填剤 |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8702761D0 SE8702761D0 (sv) | 1987-07-03 |
SE8702761L SE8702761L (sv) | 1988-01-06 |
SE466791B true SE466791B (sv) | 1992-04-06 |
Family
ID=15671190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8702761A SE466791B (sv) | 1986-07-05 | 1987-07-03 | Kolonnfyllningsmaterial och anvaendning av detta foer vaetskekromatografi och blodbehandling |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPH07104332B2 (enrdf_load_stackoverflow) |
DE (1) | DE3722102A1 (enrdf_load_stackoverflow) |
SE (1) | SE466791B (enrdf_load_stackoverflow) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5441635A (en) * | 1986-07-05 | 1995-08-15 | Asahi Kogaku Kogyo Kabushiki Kaisha | Packing material for liquid chromatography |
JPS6413453A (en) * | 1987-07-08 | 1989-01-18 | Asahi Optical Co Ltd | Packing agent for liquid chromatography |
US5039408A (en) * | 1986-07-05 | 1991-08-13 | Asahi Kogaku Kogyo K.K. | Packing material for liquid chromatography |
USRE35340E (en) * | 1986-07-05 | 1996-10-01 | Asahi Kogaku Kogyo K.K. | Packing material for liquid chromatography |
JPS63126548A (ja) * | 1986-11-14 | 1988-05-30 | Koken Co Ltd | 吸着剤 |
JPH01155263A (ja) * | 1987-12-12 | 1989-06-19 | Asahi Optical Co Ltd | 液体クロマトグラフィー用充填剤及びその製法 |
JPH01162148A (ja) * | 1987-12-18 | 1989-06-26 | Asahi Optical Co Ltd | 液体クロマトグラフィー用充填剤およびその製法 |
DE3823957A1 (de) * | 1988-07-12 | 1990-01-18 | Reinhard Dr Ballhorn | Verfahren zur abtrennung von schwermetallionen aus waessrigen loesungen |
JPH02147857A (ja) * | 1988-11-29 | 1990-06-06 | Kobe Steel Ltd | クロマトグラフィー分離用球状担体およびその製造方法 |
DE69033632T2 (de) * | 1989-04-21 | 2001-05-03 | Asahi Kogaku Kogyo K.K., Tokio/Tokyo | Filterschicht |
JPH087197B2 (ja) * | 1989-05-23 | 1996-01-29 | 積水化学工業株式会社 | 液体クロマトグラフィー用充填剤とその製造法 |
JPH0822377B2 (ja) * | 1990-03-02 | 1996-03-06 | 株式会社サンギ | カラム用充填剤 |
JPH0627098A (ja) * | 1992-05-15 | 1994-02-04 | Fuji Shirishia Kagaku Kk | クロマト分離用充填剤 |
JPH07289886A (ja) * | 1992-11-25 | 1995-11-07 | Hokkaido Sogo Gijutsu Kenkyusho:Kk | アパタイト高分散複合セラミックスおよびその製造方法 |
CH686518A5 (de) * | 1993-10-05 | 1996-04-15 | Asahi Optical Co Ltd | Granulares Polymerkomposit, Herstellungsverfahren fur dieses und diagnostische Mittel. |
DE4447927B4 (de) * | 1993-10-05 | 2006-07-27 | Pentax Corp. | Diagnosemittel und Verfahren zu dessen Herstellung |
AU2005202022A1 (en) * | 2004-05-25 | 2005-12-15 | Rohm And Haas Company | Drying method for macroporous polymers, and method of preparation and use of macroporous polymers made using the method |
JP2009106798A (ja) * | 2007-10-26 | 2009-05-21 | Hitachi Maxell Ltd | 粗面化処理が施された高密度機能性粒子、その製造方法およびそれを用いた標的物質の処理方法 |
JP5463537B2 (ja) * | 2008-02-22 | 2014-04-09 | HOYA Technosurgical株式会社 | 分離方法 |
HK1250516A1 (zh) * | 2015-05-28 | 2018-12-21 | 伊穆特丽克斯治疗股份有限公司 | 通用血液制品及其制备和使用方法 |
JP2017119230A (ja) | 2015-12-28 | 2017-07-06 | Jnc株式会社 | 吸着剤およびその製造方法 |
WO2020128021A1 (en) * | 2018-12-20 | 2020-06-25 | Solvay Sa | Particles comprising hydroxyapatite, process for making and their use |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60143762A (ja) * | 1983-10-03 | 1985-07-30 | Mitsui Toatsu Chem Inc | クロマトグラフイ−用ヒドロキシアパタイト |
-
1986
- 1986-07-05 JP JP61158412A patent/JPH07104332B2/ja not_active Expired - Lifetime
-
1987
- 1987-07-03 SE SE8702761A patent/SE466791B/sv not_active IP Right Cessation
- 1987-07-03 DE DE19873722102 patent/DE3722102A1/de active Granted
Also Published As
Publication number | Publication date |
---|---|
SE8702761D0 (sv) | 1987-07-03 |
SE8702761L (sv) | 1988-01-06 |
DE3722102C2 (enrdf_load_stackoverflow) | 1991-04-25 |
DE3722102A1 (de) | 1988-01-14 |
JPS6316044A (ja) | 1988-01-23 |
JPH07104332B2 (ja) | 1995-11-13 |
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Legal Events
Date | Code | Title | Description |
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NAL | Patent in force |
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NUG | Patent has lapsed |