SE464303B - 5-fluorouracilderivat, foerfarande foer framstaellning av detta och en anticancerkomposition - Google Patents

5-fluorouracilderivat, foerfarande foer framstaellning av detta och en anticancerkomposition

Info

Publication number
SE464303B
SE464303B SE8701118A SE8701118A SE464303B SE 464303 B SE464303 B SE 464303B SE 8701118 A SE8701118 A SE 8701118A SE 8701118 A SE8701118 A SE 8701118A SE 464303 B SE464303 B SE 464303B
Authority
SE
Sweden
Prior art keywords
compound
formula
fluorouracil
reaction
cyano
Prior art date
Application number
SE8701118A
Other languages
English (en)
Swedish (sv)
Other versions
SE8701118L (sv
SE8701118D0 (sv
Inventor
S Fujii
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61181027A external-priority patent/JPS63301880A/ja
Priority claimed from JP62034161A external-priority patent/JPS63201127A/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of SE8701118D0 publication Critical patent/SE8701118D0/xx
Publication of SE8701118L publication Critical patent/SE8701118L/xx
Publication of SE464303B publication Critical patent/SE464303B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE8701118A 1986-07-25 1987-03-18 5-fluorouracilderivat, foerfarande foer framstaellning av detta och en anticancerkomposition SE464303B (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP17646486 1986-07-25
JP61181027A JPS63301880A (ja) 1985-09-03 1986-07-30 ５−フルオロウラシル誘導体
JP62034161A JPS63201127A (ja) 1987-02-17 1987-02-17 ５−フルオロウラシル誘導体を含有する制癌剤

Publications (3)

Publication Number Publication Date
SE8701118D0 SE8701118D0 (sv) 1987-03-18
SE8701118L SE8701118L (sv) 1988-01-26
SE464303B true SE464303B (sv) 1991-04-08

Family

ID=27288338

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8701118A SE464303B (sv) 1986-07-25 1987-03-18 5-fluorouracilderivat, foerfarande foer framstaellning av detta och en anticancerkomposition

Country Status (10)

Country Link
KR (2) KR950009857B1 (fr)
CH (1) CH671578A5 (fr)
DE (1) DE3709699C2 (fr)
DK (1) DK169520B1 (fr)
ES (1) ES2004904A6 (fr)
FR (1) FR2605006B1 (fr)
GB (1) GB2192880B (fr)
IT (1) IT1207785B (fr)
NL (1) NL194043C (fr)
SE (1) SE464303B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4864021A (en) * 1984-10-30 1989-09-05 Otsuka Pharmaceutical Co., Ltd. 5-fluorouracil derivatives
NL194430C (nl) 1989-01-05 2002-04-04 Otsuka Pharma Co Ltd Niet-injecteerbaar farmaceutisch preparaat met anti-kankerwerking.
KR0172134B1 (ko) * 1990-07-19 1999-02-01 오오쓰까 아끼히코 고형 제제
ES2619937T3 (es) * 2009-10-27 2017-06-27 Delta-Fly Pharma, Inc. Nuevo derivado de 5-fluorouracilo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK174238B1 (da) * 1984-10-30 2002-10-07 Otsuka Pharma Co Ltd 5-Fluoruracilderivater, deres fremstilling og lægemidler indeholdende sådanne forbindelser
JPS61114739A (ja) * 1984-11-08 1986-06-02 Mitsubishi Rayon Co Ltd 不飽和カルボン酸製造用触媒の調製法

Also Published As

Publication number Publication date
DK133387A (da) 1988-01-26
GB2192880B (en) 1990-05-09
NL194043C (nl) 2001-05-03
IT8705150A0 (it) 1987-03-30
DK169520B1 (da) 1994-11-21
NL8700742A (nl) 1988-02-16
KR880001635A (ko) 1988-04-25
DE3709699A1 (de) 1988-02-04
CH671578A5 (fr) 1989-09-15
DK133387D0 (da) 1987-03-16
NL194043B (nl) 2001-01-02
GB2192880A (en) 1988-01-27
IT1207785B (it) 1989-06-01
FR2605006B1 (fr) 1990-01-12
KR880001630A (ko) 1988-04-25
ES2004904A6 (es) 1989-02-16
KR950011394B1 (ko) 1995-10-02
FR2605006A1 (fr) 1988-04-15
GB8706972D0 (en) 1987-04-29
SE8701118L (sv) 1988-01-26
KR950009857B1 (ko) 1995-08-29
DE3709699C2 (de) 1996-09-05
SE8701118D0 (sv) 1987-03-18

Similar Documents

Publication Publication Date Title
AU2013296420B2 (en) N-alkyl 2-(disubstituted)alkynyladenosine-5-uronamides as A2A agonists
JPH05506240A (ja) ５―ベンジルバルビツレート誘導体
MX2015002695A (es) Derivados biciclicos fusionados de sulfamoilo y su uso como medicamentos para el tratamiento de la hepatitis b.
CA2193644A1 (fr) Purine, indol et pyrimidine de (dihydroxyboryl)alkyle a substitution en n, utiles comme inhibiteurs de cytokines inflammatoires
JP6516305B2 (ja) 選択的ｊａｋ３及び／又はｊａｋ１キナーゼ阻害剤である芳香族複素環式化合物の調製方法及びその使用
SE464303B (sv) 5-fluorouracilderivat, foerfarande foer framstaellning av detta och en anticancerkomposition
JP2002519413A (ja) ヒト免疫不全ウイルスの複製を阻害するピペラジン誘導体
AU2020285269B2 (en) Bicyclic compound as RIP-1 kinase inhibitor and application thereof
WO1993019075A1 (fr) Derives acides phosphoniques antiviraux d'analogues de purine
JPH05501404A (ja) ヌクレオシド誘導体
WO1994014831A1 (fr) Nucleosides de dihydropyrimidine a proprietes antivirales
JPH04500968A (ja) ヌクレオシド誘導体
JPH0564931B2 (fr)
EP0425669B1 (fr) 1-amino-5-halogeno-uraciles, procede de preparation de ces composes, et agents depresseurs du systeme nerveux central les contenant en tant qu'ingredients actifs
JPS62501632A (ja) ４−置換−６−アリ−ルピリミジン化合物
JPH061768A (ja) キノリン誘導体のフマル酸塩
KR20190026910A (ko) 4-시아노-n-(2-(4,4-다이메틸사이클로헥스-1-엔-1-일)-6-(2,2,6,6-테트라메틸테트라하이드로-2h-피란-4-일)피리딘-3-일)-1h-이미다졸-2-카르복스아미드의 결정질 형태
CN114206841A (zh) Cd73抑制剂
CA1086316A (fr) Nucleosides acycliques de purine
CN112142731B (zh) 一种2，4-二取代嘧啶衍生物及其制备方法和用途
WO2001044195A1 (fr) Dérivés hétérocycliques et médicaments
JPS6360929A (ja) 抗腫瘍剤
CN102666563A (zh) 作为a2a受体激动剂的烷氧基羰基氨基炔基腺苷化合物及其衍生物
JP2512735B2 (ja) フルオロメチルチオリボ−ス誘導体及び腫瘍処置剤
US20170283452A9 (en) N-alkyl 2-(disubstituted)alkynyladenosine-5-uronamides as a2a agonists

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8701118-5

Format of ref document f/p: F

NUG Patent has lapsed