SE452622B - N-(vinblastinoyl-23)-derivat av aminosyror, deras framstellning och farmaceutiska kompositioner - Google Patents

N-(vinblastinoyl-23)-derivat av aminosyror, deras framstellning och farmaceutiska kompositioner

Info

Publication number
SE452622B
SE452622B SE8206981A SE8206981A SE452622B SE 452622 B SE452622 B SE 452622B SE 8206981 A SE8206981 A SE 8206981A SE 8206981 A SE8206981 A SE 8206981A SE 452622 B SE452622 B SE 452622B
Authority
SE
Sweden
Prior art keywords
group
compounds
ethyl
tryptophanate
hydrogen atom
Prior art date
Application number
SE8206981A
Other languages
English (en)
Swedish (sv)
Other versions
SE8206981D0 (sv
SE8206981L (sv
Inventor
A B L Trouet
J A A J Hannart
K S B Rao
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem Sa filed Critical Omnichem Sa
Publication of SE8206981D0 publication Critical patent/SE8206981D0/xx
Publication of SE8206981L publication Critical patent/SE8206981L/xx
Publication of SE452622B publication Critical patent/SE452622B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE8206981A 1981-12-08 1982-12-07 N-(vinblastinoyl-23)-derivat av aminosyror, deras framstellning och farmaceutiska kompositioner SE452622B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU83822A LU83822A1 (fr) 1981-12-08 1981-12-08 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique

Publications (3)

Publication Number Publication Date
SE8206981D0 SE8206981D0 (sv) 1982-12-07
SE8206981L SE8206981L (sv) 1983-06-09
SE452622B true SE452622B (sv) 1987-12-07

Family

ID=19729780

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8206981A SE452622B (sv) 1981-12-08 1982-12-07 N-(vinblastinoyl-23)-derivat av aminosyror, deras framstellning och farmaceutiska kompositioner

Country Status (24)

Country Link
JP (1) JPS58116491A (ja)
AT (1) AT390958B (ja)
AU (1) AU564951B2 (ja)
BE (1) BE895262A (ja)
CA (1) CA1198422A (ja)
CH (1) CH655727A5 (ja)
DD (1) DD205906A5 (ja)
DE (1) DE3245269A1 (ja)
DK (1) DK161833C (ja)
ES (1) ES8401768A1 (ja)
FR (1) FR2517680B1 (ja)
GB (1) GB2111055B (ja)
GR (1) GR77280B (ja)
HU (1) HU187803B (ja)
IE (1) IE55283B1 (ja)
IL (1) IL67366A (ja)
IT (1) IT1157126B (ja)
LU (1) LU83822A1 (ja)
NL (1) NL8204711A (ja)
NZ (1) NZ202708A (ja)
OA (1) OA07270A (ja)
PT (1) PT75949B (ja)
SE (1) SE452622B (ja)
ZA (1) ZA828823B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484691D1 (de) * 1983-04-29 1991-07-18 Omnichem Sa Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
CA1335686C (fr) * 1986-01-13 1995-05-23 Rao K. S. P. Bhushana Vinblastine et composition pharmaceutique les contenant
US4906086A (en) * 1987-06-19 1990-03-06 Honda Giken Kogyo Kabushiki Kaisha Rearview mirror device for motorcycles
FR2626882B1 (fr) * 1988-02-08 1991-11-08 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
WO2014169697A1 (zh) * 2013-04-19 2014-10-23 暨南大学 长春碱类衍生物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US3848234A (en) * 1973-04-04 1974-11-12 Sperry Rand Corp Multi-processor system with multiple cache memories
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.

Also Published As

Publication number Publication date
IE55283B1 (en) 1990-08-01
IL67366A0 (en) 1983-03-31
DK161833C (da) 1992-01-20
ES517942A0 (es) 1984-01-01
ZA828823B (en) 1983-09-28
ES8401768A1 (es) 1984-01-01
AU564951B2 (en) 1987-09-03
DK161833B (da) 1991-08-19
NL8204711A (nl) 1983-07-01
JPS58116491A (ja) 1983-07-11
PT75949B (fr) 1985-10-04
GR77280B (ja) 1984-09-11
BE895262A (fr) 1983-06-07
GB2111055A (en) 1983-06-29
GB2111055B (en) 1985-07-10
FR2517680A1 (fr) 1983-06-10
NZ202708A (en) 1986-01-24
LU83822A1 (fr) 1983-09-01
AU9084782A (en) 1983-06-16
DE3245269A1 (de) 1983-07-21
CA1198422A (en) 1985-12-24
DK541882A (da) 1983-06-09
FR2517680B1 (fr) 1990-05-25
JPH0449557B2 (ja) 1992-08-11
IL67366A (en) 1987-01-30
PT75949A (fr) 1983-01-01
OA07270A (fr) 1984-04-30
IT1157126B (it) 1987-02-11
HU187803B (en) 1986-02-28
DD205906A5 (de) 1984-01-11
SE8206981D0 (sv) 1982-12-07
IE822906L (en) 1983-06-08
CH655727A5 (fr) 1986-05-15
AT390958B (de) 1990-07-25
ATA444982A (de) 1990-01-15
SE8206981L (sv) 1983-06-09
IT8268431A0 (it) 1982-12-07

Similar Documents

Publication Publication Date Title
CN109563120B (zh) 半乳糖凝集素的α-D-半乳糖苷抑制剂
EP0005051B1 (en) 4-desacetyl vlb c-3 carboxhydrazides, their preparation and formulations containing them
CN113645977A (zh) 化合物、组合物和疾病治疗方法
HU185261B (en) Process for preparing n-/vinblastinoyl-23/-derivatives of some aminoacids and peptides
EP3866925A1 (en) Prodrug of galactoside inhibitors of galectins
US11046725B2 (en) Galactoside inhibitor of galectins
DK141511B (da) Analogifremgangsmåde til fremstilling af derivater af vindblastin, leurosidin eller leurocristin.
SE452622B (sv) N-(vinblastinoyl-23)-derivat av aminosyror, deras framstellning och farmaceutiska kompositioner
KR100255074B1 (ko) 콜히친 유도체 및 그의 치료적 용도
KR100306430B1 (ko) 콜히친골격화합물과그들의의약품으로서의용도및이들을함유한조성물
EP0173624A2 (en) 4-(guanin-9-yl) butanals and antiviral compositions containing them
HU176226B (en) Process for producing 4-deacetyl- or 4-deacetoxy-vinblastin-3-carboxamide derivatives
JPH075608B2 (ja) ビンブラスチン誘導体
KR20160087899A (ko) 탁산(Taxane) 화합물 및 제조방법과 그 이용
EP0089678B1 (en) Novel 2-beta-d-ribofuranosylselenazole-4-carboxamide compounds and methods for their production
JP2003527371A (ja) Ｎ−デアセチルチオコルヒチン誘導体及びそれを含有する医薬組成物
JPS58103392A (ja) ３位においてチオメチルヘテロ環基により置換されたセフアロスポリンの新規な誘導体、これら化合物の製造方法およびこれらを含有する薬学的組成物
EP0207336B1 (en) Nitro derivatives of vinblastine-type bis-indoles, a process for preparing same and pharmaceutical compositions containing them
FR2459231A1 (fr) Nouveaux derives de la cystamine utiles comme medicaments
AU2005318227A1 (en) Stereoselective process and crystalline forms of a camptothecin
US4438266A (en) Triazolopyrazinamines useful as adjuncts to radiation therapy
KR970004044B1 (ko) 약물동력학적으로 개선된 세팔로스포린 유도체, 그의 제조방법, 그를 함유하는 약제학적 조성물 및 합성 중간체
EP0205168B1 (en) Furfuryl derivatives of vinblastine-type bis-indoles, a process for preparing same and pharmaceutical compositions containing them
PL188075B1 (pl) Rozpuszczalne w wodzie C-pierścieniowe analogi 20(S)-kamptotecyny, kompozycja farmaceutyczna zawierająca te związki, ich zastosowanie oraz sposób wytwarzania
SE442116B (sv) Sett att framstella cytostatiska foreningar innefattande derivat av vinblastin och leurosidin jemte farmaceutiska beredningar derav

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8206981-6

Effective date: 19930709

Format of ref document f/p: F