SE452619B - Nytt forfarande for framstellning av cefalosporiner - Google Patents

Nytt forfarande for framstellning av cefalosporiner

Info

Publication number
SE452619B
SE452619B SE8105452A SE8105452A SE452619B SE 452619 B SE452619 B SE 452619B SE 8105452 A SE8105452 A SE 8105452A SE 8105452 A SE8105452 A SE 8105452A SE 452619 B SE452619 B SE 452619B
Authority
SE
Sweden
Prior art keywords
formula
het
acid
mmol
thiol ester
Prior art date
Application number
SE8105452A
Other languages
English (en)
Swedish (sv)
Other versions
SE8105452L (sv
Inventor
S Iimura
J Okumura
T Naito
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE8105452L publication Critical patent/SE8105452L/xx
Publication of SE452619B publication Critical patent/SE452619B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE8105452A 1980-09-15 1981-09-14 Nytt forfarande for framstellning av cefalosporiner SE452619B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/187,273 US4316024A (en) 1980-09-15 1980-09-15 Dioxo piperazine compounds

Publications (2)

Publication Number Publication Date
SE8105452L SE8105452L (sv) 1982-03-16
SE452619B true SE452619B (sv) 1987-12-07

Family

ID=22688303

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8105452A SE452619B (sv) 1980-09-15 1981-09-14 Nytt forfarande for framstellning av cefalosporiner
SE8505891A SE458607B (sv) 1980-09-15 1985-12-12 1-metyltetrazol-5-yl-(4-etyl-2,3-dioxopierazin-1-yl)-karbonyltiolat och tetrazolo-(1,5-b)pyridazin-6-yl-(4-etyl-2,3-dioxopiperazin-l-yl) karbonyltiolat

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8505891A SE458607B (sv) 1980-09-15 1985-12-12 1-metyltetrazol-5-yl-(4-etyl-2,3-dioxopierazin-1-yl)-karbonyltiolat och tetrazolo-(1,5-b)pyridazin-6-yl-(4-etyl-2,3-dioxopiperazin-l-yl) karbonyltiolat

Country Status (10)

Country Link
US (1) US4316024A (ru)
JP (2) JPS5781490A (ru)
DK (2) DK161521C (ru)
ES (1) ES8301238A1 (ru)
FI (1) FI76349C (ru)
GR (1) GR74670B (ru)
HU (1) HU184882B (ru)
IT (1) IT1209898B (ru)
SE (2) SE452619B (ru)
YU (2) YU44963B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0047014B1 (en) * 1980-09-02 1986-01-15 Asahi Kasei Kogyo Kabushiki Kaisha Novel thioesters and process for the preparation of the same
CH648038A5 (de) * 1981-01-19 1985-02-28 Sandoz Ag 7-((carboxymethoxyimino)-1h-pyrazol-3-yl-acetyl)amino-3-desacetoxy-3-(1-methyl-1h-tetrazol-5-yl-thio)cephalosporansaeure und salze, verfahren zur herstellung und verwendung.
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
DE3485860T2 (de) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
SI8711089A8 (en) * 1987-06-11 1996-08-31 Krka Tovarna Zdravil Process for preparation of 6-/d(-)-alpha-(4-ethyl-2,3-dioxo-1- piperazine-carboxyamido)-phenylacetamido/-penicillanic acid
CN102372728B (zh) * 2011-11-28 2013-12-11 齐鲁安替制药有限公司 一种头孢菌素类化合物的合成方法
CN102372729B (zh) * 2011-12-14 2014-09-24 哈药集团制药总厂 一种合成头孢哌酮钠化合物的新方法
CN103641847B (zh) * 2013-11-28 2016-04-20 山东鑫泉医药有限公司 头孢哌酮酸的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087424A (en) * 1974-05-09 1978-05-02 Toyama Chemical Co., Ltd. Novel penicillins and cephalosporins and process for producing the same
JPS51115491A (en) * 1975-04-03 1976-10-12 Sumitomo Chem Co Ltd Method for preparing 77* *44hydroxyy1*5 naphthyridinee33carboxyamino ** phenylacetamido*cephalosporins
JPS6052711B2 (ja) * 1978-03-09 1985-11-20 旭化成株式会社 セフアロスポリン化合物の製法
JPS5520711A (en) * 1978-08-01 1980-02-14 Asahi Chem Ind Co Ltd New 1,3,4-thiadiazol-5-ylthiol esters and their preparation
US4198504A (en) * 1978-11-02 1980-04-15 Bristol-Myers Company [3-(Pyridinium)-7-(naphthyiridinyl carbonylamino)acetamido]cephalosporanic acid derivatives

Also Published As

Publication number Publication date
YU44963B (en) 1991-06-30
DK8991A (da) 1991-01-18
SE8505891D0 (sv) 1985-12-12
DK161521B (da) 1991-07-15
SE8505891L (sv) 1985-12-12
DK161521C (da) 1991-12-23
SE8105452L (sv) 1982-03-16
DK164505C (da) 1992-11-23
JPH0285278A (ja) 1990-03-26
FI76349B (fi) 1988-06-30
JPS5781490A (en) 1982-05-21
ES505465A0 (es) 1982-12-01
JPH0246587B2 (ru) 1990-10-16
DK404181A (da) 1982-03-16
HU184882B (en) 1984-10-29
YU213181A (en) 1984-06-30
DK164505B (da) 1992-07-06
ES8301238A1 (es) 1982-12-01
FI76349C (fi) 1988-10-10
YU44754B (en) 1991-02-28
JPH0245636B2 (ru) 1990-10-11
IT8149296A0 (it) 1981-09-15
YU217483A (en) 1985-10-31
US4316024A (en) 1982-02-16
SE458607B (sv) 1989-04-17
IT1209898B (it) 1989-08-30
FI812821L (fi) 1982-03-16
DK8991D0 (da) 1991-01-18
GR74670B (ru) 1984-07-02

Similar Documents

Publication Publication Date Title
HU198044B (en) Process for production of 2-oxo-1-/(substituated sulphonil)-/amin/-carbonil)-asetidines and medical preparatives containing these substances
SE452619B (sv) Nytt forfarande for framstellning av cefalosporiner
US4760060A (en) 3-heteroaralkylthio carbacephem compounds and antibacterial pharmaceutical composition
CS243499B2 (en) Method of new beta-lactams production
SE470259B (sv) Mellanprodukter till cefalosporiner
Crowell et al. 3-Sulfonyl-1-carba-1-dethiacephems
US4695639A (en) Thiazole derivatives
AU690482B2 (en) Process for producing cephalosporin antibiotics
SU1114338A3 (ru) Способ получени производных цефалоспорин-1-оксида
EP0329785A1 (en) Cephalosporin derivatives
EP0289002B1 (en) Novel cephalosporin compounds and antibacterial agents
Yoshida et al. Studies on anti-Helicobacter pylori agents. Part 2: New cephem derivatives
EP0191989B1 (en) Antibiotic isoxazole derivatives, their production and use
NL8203124A (nl) 2-oxo-azetidinen en werkwijzen voor het bereiden en toepassen van deze verbindingen.
US3953439A (en) Substituted phenylglycylcephalosporins
SE445738B (sv) Forfarande for framstellning av en 3-karbamoyloximetylcefalosporinforening
US4107440A (en) Intermediates for preparing substituted phenylglycylcephalosporins
US4044047A (en) Intermediates for preparing substituted phenylglycylcephalosporins
GB2146996A (en) 3-azidocephalosporins as intermediates and novel antibacterial agents
GB2193213A (en) 6-trifluoromethyl-1H-benzotriazol-1-yl diphenylphosphate and its use in preparing cephalosporin derivatives
US4497811A (en) 1-Oxadethiacephalosporin compound and antibacterial agent containing the _same
Inamoto et al. STUDIES ON β-LACTAM ANTIBIOTICS XIX. STRUCTURE-ACTIVITY RELATIONSHIPS OF CEPHALOSPORINS HAVING A THIADIAZOLYLTHIOMETHYL GROUP AT THE C-3 SIDE CHAIN
KR930001405B1 (ko) 2-(4-치환아미노-3-옥소-이속사졸리디닐)-5-옥소-2-테트라히드로푸란카르복실산 유도체의 제조방법
US4022895A (en) Substituted phenylglycylcephalosporins
US4013764A (en) Pharmaceutical compositions comprising substituted phenylglycylcephalosporins and methods of treating bacterial infections

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8105452-0

Effective date: 19940410

Format of ref document f/p: F