SE448239B - Nya penicillinderivat och deras framstellning - Google Patents

Nya penicillinderivat och deras framstellning

Info

Publication number
SE448239B
SE448239B SE7902916A SE7902916A SE448239B SE 448239 B SE448239 B SE 448239B SE 7902916 A SE7902916 A SE 7902916A SE 7902916 A SE7902916 A SE 7902916A SE 448239 B SE448239 B SE 448239B
Authority
SE
Sweden
Prior art keywords
compound
mmol
penam
carboxylic acid
acetyl
Prior art date
Application number
SE7902916A
Other languages
English (en)
Swedish (sv)
Other versions
SE7902916L (sv
Inventor
R L Cundall
D Walker
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE7902916L publication Critical patent/SE7902916L/xx
Publication of SE448239B publication Critical patent/SE448239B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE7902916A 1978-04-03 1979-04-02 Nya penicillinderivat och deras framstellning SE448239B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/893,092 US4322347A (en) 1978-04-03 1978-04-03 2-Carbamoyloxymethyl-penicillin derivatives

Publications (2)

Publication Number Publication Date
SE7902916L SE7902916L (sv) 1979-10-04
SE448239B true SE448239B (sv) 1987-02-02

Family

ID=25401020

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7902916A SE448239B (sv) 1978-04-03 1979-04-02 Nya penicillinderivat och deras framstellning
SE8402090A SE458610B (sv) 1978-04-03 1984-04-13 Foerfarande foer framstaellning av cefem-foereningar
SE8402089A SE458609B (sv) 1978-04-03 1984-04-13 7-acyl-3-karbamoyloxi-3-metyl-cefam-foereningar samt foerfarande foer framstaellning daerav

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE8402090A SE458610B (sv) 1978-04-03 1984-04-13 Foerfarande foer framstaellning av cefem-foereningar
SE8402089A SE458609B (sv) 1978-04-03 1984-04-13 7-acyl-3-karbamoyloxi-3-metyl-cefam-foereningar samt foerfarande foer framstaellning daerav

Country Status (15)

Country Link
US (1) US4322347A (ja)
JP (1) JPS54132594A (ja)
BE (1) BE875247A (ja)
CA (1) CA1140915A (ja)
CH (1) CH642080A5 (ja)
DE (1) DE2912483A1 (ja)
DK (1) DK129779A (ja)
FR (1) FR2421903B1 (ja)
GB (1) GB2017705B (ja)
IE (1) IE49046B1 (ja)
IT (1) IT1116851B (ja)
LU (1) LU81108A1 (ja)
NL (1) NL7902443A (ja)
SE (3) SE448239B (ja)
YU (5) YU41860B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374982A (en) * 1979-11-07 1983-02-22 Bristol-Myers Company Cepham compounds
IT1148888B (it) * 1980-07-15 1986-12-03 Schiena Ricerche Di Composti antibiotici
ZW13589A1 (en) * 1988-10-31 1990-06-13 Hoffmann La Roche Panicillanic acid derivatives
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
AU2012357986B2 (en) 2011-12-20 2017-02-02 Riboscience Llc 4'-Azido, 3'-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication
SI2794629T1 (sl) 2011-12-20 2017-10-30 Riboscience Llc 2'4'-difluoro-2'-metil substituirani nukleozidni derivati k0t zaviralci replikacije hcv-rna
SG11201509427RA (en) 2013-05-16 2015-12-30 Riboscience Llc 4'-azido, 3'-deoxy-3'-fluoro substituted nucleoside derivatives
US20180200280A1 (en) 2013-05-16 2018-07-19 Riboscience Llc 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
BR112015028764B1 (pt) 2013-05-16 2022-09-27 Riboscience Llc Derivados de nucleosídeo de 4-fluoro-2-metil substituídos como inibidores de replicação de rna do hcv
SG11202002431SA (en) 2017-09-21 2020-04-29 Riboscience Llc 4'-fluoro-2'-methyl substituted nucleoside derivatives as inhibitors of hcv rna replication

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3275626A (en) * 1962-07-31 1966-09-27 Lilly Co Eli Penicillin conversion via sulfoxide
US3714156A (en) * 1970-06-22 1973-01-30 Univ California Lactam process
BE787618A (fr) 1971-08-17 1973-02-16 Gist Brocades Nv Procede pour preparer des composes heterocycliques
GB1425827A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephalosporins
US4218374A (en) * 1972-10-20 1980-08-19 Fujisawa Pharmaceutical Company, Limited Penam derivatives
GB1465893A (en) * 1973-02-09 1977-03-02 Gist Brocades Nv I-carboxypropenyl-4-iminothio-azetidine-2-one derivatives methods for their preparation and use
DE2309599A1 (de) * 1973-02-26 1974-09-05 Bayer Ag Verfahren zur herstellung von 7-acylamino-desacetoxy-cephalosporansaeurederivaten
DE2320040A1 (de) 1973-04-19 1974-11-07 Bayer Ag Verfahren zur herstellung von 7acylamino-desacetoxy-cephalosporansaeureester
US4010156A (en) * 1973-04-19 1977-03-01 American Home Products Corporation Process for the rearrangement of penicillins to cephalosporins and intermediate compounds thereof
GB1467604A (en) * 1974-06-27 1977-03-16 Toyama Chemical Co Ltd Bis-type penicillins and process for producing the same
FR2340093A1 (fr) 1976-02-05 1977-09-02 Roussel Uclaf Derives de l'acide 3-carbamoyloxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1573614A (en) * 1976-02-25 1980-08-28 Leo Pharm Prod Ltd Amidinopenicillanoyloxyalkyl cephalosporanates
DE2655949A1 (de) * 1976-12-10 1978-06-15 Gruenenthal Gmbh Neue cephalosporin- und penicillinderivate, verfahren zu deren herstellung und diese produkte enthaltende arzneimittel
US4182711A (en) * 1978-04-27 1980-01-08 Bristol-Myers Company Antibacterial agents of the β-lactam type
CA1125745A (en) * 1978-11-20 1982-06-15 Joseph Kaspi PROCESS FOR PREPARING .beta.-LACTAM ANTIBIOTICS

Also Published As

Publication number Publication date
BE875247A (fr) 1979-10-01
YU75679A (en) 1983-01-21
JPH0217557B2 (ja) 1990-04-20
IT7948457A0 (it) 1979-03-23
JPS54132594A (en) 1979-10-15
GB2017705A (en) 1979-10-10
YU42802B (en) 1988-12-31
DK129779A (da) 1979-10-04
SE458609B (sv) 1989-04-17
CA1140915A (en) 1983-02-08
FR2421903B1 (fr) 1986-08-29
IE790947L (en) 1979-10-03
YU220482A (en) 1983-01-21
IT1116851B (it) 1986-02-10
SE7902916L (sv) 1979-10-04
YU220782A (en) 1983-01-21
SE8402090D0 (sv) 1984-04-13
DE2912483A1 (de) 1979-10-11
SE458610B (sv) 1989-04-17
YU220582A (en) 1983-01-21
LU81108A1 (de) 1979-11-07
CH642080A5 (fr) 1984-03-30
SE8402090L (sv) 1984-04-13
YU220682A (en) 1983-01-21
YU42803B (en) 1988-12-31
US4322347A (en) 1982-03-30
GB2017705B (en) 1982-10-27
NL7902443A (nl) 1979-10-05
SE8402089L (sv) 1984-04-13
YU41860B (en) 1988-02-29
FR2421903A1 (fr) 1979-11-02
YU42050B (en) 1988-04-30
SE8402089D0 (sv) 1984-04-13
IE49046B1 (en) 1985-07-24
YU43096B (en) 1989-02-28

Similar Documents

Publication Publication Date Title
SE461913B (sv) Nya beta-laktamasinhibitor-foereningar vilka aer mellanprodukter vid frammstaellning av antibiotiskt verksamma beta-laktamasfoereningar
JPH05509089A (ja) セファロスポリンおよび同族体、製法および医薬組成物
SE448239B (sv) Nya penicillinderivat och deras framstellning
SE405857B (sv) Forfarande for substituerande av en grupp i 6-resp 7-stellning hos en penicillansyraforening eller cefalosporansyraforening
EP0303172A2 (de) Oxyimino-Cephalosporine
US4122086A (en) Isopenicillins
US4145418A (en) Thienopyridine substituted cephalosporins
US4678782A (en) 3S-formamido azetidinone antibacterial agents, their preparation and use
US4310459A (en) Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters
US3941779A (en) Method for producing 2-(substituted thio)-3-cephem derivatives
US4705852A (en) 1-oxadethia cephalosporin hydroxamic acid derivatives
DE3035259A1 (de) Cephalosporinverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
YOSHIDA et al. STUDIES ON MONOCYCLIC β-LACTAM ANTIBIOTICS II. SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 3-ACYLAMINO-2-AZETIDINONE-1-OXYSULFONIC ACIDS
US4374982A (en) Cepham compounds
US4534898A (en) 1-Oxa-1-dethia-cephalosporin derivatives
CA1050010A (en) Process for preparing-3-methyl-4-(5-tetrazolyl)-a3-cephem compounds
US4518773A (en) "3-Carbamoyloxy cephalosporins"
US4426520A (en) 3-Carbamoyloxy-cepham-4-carboxylic acid derivatives
US4224442A (en) 7-Ureido acetamido substituted cephalosporin antibiotics
US4349551A (en) Penicillin derivatives and compositions containing them
SE445738B (sv) Forfarande for framstellning av en 3-karbamoyloximetylcefalosporinforening
US3985740A (en) 7-[D-(α-amino-α-phenyl-, 2-thienyl- and 3-thienylacetamido)]-3-(5-methylthiazol-2-yl)carbonylthiomethyl-3-cephem-4-carboxylic acids
CA1157013A (en) Process for the preparation of (substituted)-2- carbamoyloxymethylpenam and (substituted)3- carbamoyloxycepham
JPS58128387A (ja) 新規β−ラクタム化合物およびその製法と用途
US4407755A (en) 6-Amino penam derivatives

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7902916-1

Effective date: 19880318

Format of ref document f/p: F