SE447872B - Metallsalt av heparin av injicerbar kvalitet och forfarande for dess framstellning - Google Patents

Metallsalt av heparin av injicerbar kvalitet och forfarande for dess framstellning

Info

Publication number
SE447872B
SE447872B SE7808487A SE7808487A SE447872B SE 447872 B SE447872 B SE 447872B SE 7808487 A SE7808487 A SE 7808487A SE 7808487 A SE7808487 A SE 7808487A SE 447872 B SE447872 B SE 447872B
Authority
SE
Sweden
Prior art keywords
heparin
salt
solution
metal
oxalate
Prior art date
Application number
SE7808487A
Other languages
English (en)
Swedish (sv)
Other versions
SE7808487L (sv
Inventor
J Goulay
J Choay
J-P Duclos
Original Assignee
Choay Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB33170/77A external-priority patent/GB1602439A/en
Application filed by Choay Sa filed Critical Choay Sa
Publication of SE7808487L publication Critical patent/SE7808487L/xx
Publication of SE447872B publication Critical patent/SE447872B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
SE7808487A 1977-08-08 1978-08-08 Metallsalt av heparin av injicerbar kvalitet och forfarande for dess framstellning SE447872B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB33170/77A GB1602439A (en) 1977-08-08 1977-08-08 Purified heparin
GB5204777 1977-12-14

Publications (2)

Publication Number Publication Date
SE7808487L SE7808487L (sv) 1979-02-09
SE447872B true SE447872B (sv) 1986-12-22

Family

ID=26261753

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7808487A SE447872B (sv) 1977-08-08 1978-08-08 Metallsalt av heparin av injicerbar kvalitet och forfarande for dess framstellning

Country Status (14)

Country Link
US (1) US4652555A (en, 2012)
JP (1) JPS5446809A (en, 2012)
AT (1) AT371713B (en, 2012)
AU (1) AU529432B2 (en, 2012)
CA (1) CA1105453A (en, 2012)
CH (1) CH636888A5 (en, 2012)
DE (1) DE2834702A1 (en, 2012)
DK (1) DK350078A (en, 2012)
ES (1) ES472430A1 (en, 2012)
FR (1) FR2400036A1 (en, 2012)
IE (1) IE47169B1 (en, 2012)
IT (1) IT1192564B (en, 2012)
NL (1) NL7808292A (en, 2012)
SE (1) SE447872B (en, 2012)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2461719A2 (fr) * 1979-07-20 1981-02-06 Choay Sa Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
EP0245813B2 (en) * 1986-05-16 2000-03-22 ITALFARMACO S.p.A. EDTA-free heparins, heparin fractions and fragments, processes for their preparation and pharmaceutical compositions containing them
AR243204A1 (es) * 1986-11-21 1993-07-30 Ajorca Sa Un metodo para la depolimerizacion quimica de polisacaridos.
SE8702254D0 (sv) * 1987-05-29 1987-05-29 Kabivitrum Ab Novel heparin derivatives
USRE38743E1 (en) 1990-06-26 2005-06-14 Aventis Pharma S.A. Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events
JP2001231595A (ja) * 1999-12-15 2001-08-28 Fuaruko Bio Syst:Kk 特異的破骨細胞由来酸性ホスファターゼの測定方法
JP4828795B2 (ja) 2002-03-11 2011-11-30 モメンタ ファーマシューティカルズ インコーポレイテッド 硫酸化多糖類の分析
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
AU2009250803A1 (en) * 2008-05-20 2009-11-26 Crystal Clear Partnership Separation of polysaccharides by charge density gradient
ES2340902B1 (es) * 2008-07-01 2011-05-03 Laboratorios Farmaceuticos Rovi, S.A. Composicion farmaceutica con glicosaminoglicanos y su uso en tratamiento de ulceras cronicas.
US8435795B2 (en) * 2010-01-19 2013-05-07 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
DK2617737T3 (en) * 2010-09-14 2017-04-03 Univ Miyazaki HIGH PURPOSE HEPARIN AND PREPARATION PROCEDURE
WO2012115952A1 (en) 2011-02-21 2012-08-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3135660A (en) * 1956-11-09 1964-06-02 Riker Laboratories Inc Method for purifying sulfated carbohydrates with oxidizing agents
US3482014A (en) * 1966-06-29 1969-12-02 Canada Packers Ltd Orally active heparin and method for making and using same
FR2225406A1 (en) * 1973-04-13 1974-11-08 Choay Sa Sodium-free heparin salts - by cation exchange of sodium salts, anticoagulants without side-effects
CA1042001A (en) * 1973-04-13 1978-11-07 Choay S.A. Mixed heparin salts

Also Published As

Publication number Publication date
AT371713B (de) 1983-07-25
CH636888A5 (fr) 1983-06-30
FR2400036A1 (fr) 1979-03-09
DK350078A (da) 1979-02-09
NL7808292A (nl) 1979-02-12
ATA577078A (de) 1982-12-15
JPS6129327B2 (en, 2012) 1986-07-05
JPS5446809A (en) 1979-04-13
DE2834702A1 (de) 1979-02-22
DE2834702C2 (en, 2012) 1988-11-10
IE47169B1 (en) 1984-01-11
ES472430A1 (es) 1979-03-16
AU529432B2 (en) 1983-06-09
FR2400036B1 (en, 2012) 1980-09-19
AU3874878A (en) 1980-02-14
CA1105453A (en) 1981-07-21
IT1192564B (it) 1988-04-20
IE781616L (en) 1979-02-08
US4652555A (en) 1987-03-24
SE7808487L (sv) 1979-02-09
IT7826580A0 (it) 1978-08-08

Similar Documents

Publication Publication Date Title
DE69631996T2 (de) Verfahren zur Herstellung von acylierten Proteinpuder
SE447872B (sv) Metallsalt av heparin av injicerbar kvalitet och forfarande for dess framstellning
DE69632224T2 (de) Reduzierung von Gelation von Fettsäureacylierten Proteinen unter Nutzung von Zitratpuffer
KR0154984B1 (ko) 은행잎 추출물 및 이 추출물 제조방법과 이 추출물을 함유한 약제조성물
FI86141C (fi) Foerfarande foer framstaellning av peritoneal dialysloesning.
JPS5874617A (ja) 人由来血液凝固第７因子含有水溶液の加熱処理方法
EP0143478B1 (en) Stable, aqueous, acidic solution of cis-platinum, suitable for injection
US3933996A (en) Composition comprising radioactive labeled-fibrinogen and albumin
US4476109A (en) Method of preparing gamma globulin suitable for intravenous administration
US4379086A (en) Method of preparing immunoglobulin suitable for intravenous administration using PEG
JPS61197521A (ja) ヘパリン製剤
EP0092186B1 (en) Method of preparing gamma globulin suitable for intravenous administration
NO322334B1 (no) Lyofilisert preparat av human benmorfogenetisk faktor MP52, og fremgangsmate for fremstilling av et lyofilisert preparat av human benmorfogenetisk faktor MP52
GB2027728A (en) Physiologically Acceptable Heparin
CN106361969A (zh) 一种提高参麦药物注射制剂稳定性药物组合物的制备方法
JPH0751064A (ja) 液状パパインとその製造法
DE2459515C3 (de) Arzneimittelzubereitungen mit antidiabetischer Wirkung
US3035983A (en) Process for the production of cobalamin/peptide compositions
KR960010622B1 (ko) 은행잎으로부터 유효활성물질을 추출정제하는 방법
CA1043775A (en) Process for recovering glucagon
CN106474056A (zh) 一种提高叶黄素药物注射制剂稳定性的注射用药物组合物
CN106214629A (zh) 一种灯盏花素药物注射制剂稳定性组合物的制备方法
JPH07247216A (ja) 安定な抗ウィルス注射剤の製法
CN116262101A (zh) 丁苯酞小水针及其制备方法和应用
CN120241792A (zh) 一种优化垂体后叶注射液提纯工艺提高产品质量的方法

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7808487-8

Effective date: 19940310

Format of ref document f/p: F