SE446185B - Forfarande for framstellning av pyridinylaminoalkyletrar - Google Patents

Forfarande for framstellning av pyridinylaminoalkyletrar

Info

Publication number
SE446185B
SE446185B SE7802927A SE7802927A SE446185B SE 446185 B SE446185 B SE 446185B SE 7802927 A SE7802927 A SE 7802927A SE 7802927 A SE7802927 A SE 7802927A SE 446185 B SE446185 B SE 446185B
Authority
SE
Sweden
Prior art keywords
formula
acid
group
solvent
methyl
Prior art date
Application number
SE7802927A
Other languages
English (en)
Swedish (sv)
Other versions
SE7802927L (sv
Inventor
Philipsborn G Von
W Boell
D Lenke
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of SE7802927L publication Critical patent/SE7802927L/xx
Publication of SE446185B publication Critical patent/SE446185B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C2204/00—Features not otherwise provided for
    • A61C2204/002—Features not otherwise provided for using batteries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SE7802927A 1977-03-17 1978-03-14 Forfarande for framstellning av pyridinylaminoalkyletrar SE446185B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772711655 DE2711655A1 (de) 1977-03-17 1977-03-17 Pyridinyl-aminoalkylaether

Publications (2)

Publication Number Publication Date
SE7802927L SE7802927L (sv) 1978-09-18
SE446185B true SE446185B (sv) 1986-08-18

Family

ID=6003884

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7802927A SE446185B (sv) 1977-03-17 1978-03-14 Forfarande for framstellning av pyridinylaminoalkyletrar

Country Status (27)

Country Link
US (1) US4206117A (nl)
JP (1) JPS53116382A (nl)
AT (2) AT364360B (nl)
AU (1) AU525566B2 (nl)
BE (1) BE864917A (nl)
CA (1) CA1108148A (nl)
CH (1) CH638186A5 (nl)
CS (2) CS202011B2 (nl)
DD (1) DD134090A5 (nl)
DE (1) DE2711655A1 (nl)
DK (1) DK118578A (nl)
ES (1) ES467931A1 (nl)
FI (1) FI74962C (nl)
FR (1) FR2383930A1 (nl)
GB (1) GB1599061A (nl)
GR (1) GR64096B (nl)
HU (1) HU177287B (nl)
IE (1) IE46484B1 (nl)
IL (1) IL54265A0 (nl)
IT (1) IT1093796B (nl)
LU (1) LU79235A1 (nl)
NL (1) NL189563C (nl)
NO (1) NO150605C (nl)
SE (1) SE446185B (nl)
SU (2) SU799658A3 (nl)
YU (2) YU63678A (nl)
ZA (1) ZA781552B (nl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474781A (en) * 1979-04-02 1984-10-02 Merck & Co., Inc. Treating hypertension with aminoalkoxypyridines
DE3008522A1 (de) * 1980-03-06 1981-09-17 Basf Ag, 6700 Ludwigshafen 4-(alpha)-cycloamino-arylmethyl-6-methyl-1,3-dihydro-furo (3,4-c) -pyridin-7-ole, ihre herstellung und verwendung
IL62602A (en) * 1980-05-19 1984-06-29 Labaz Sanofi Nv Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them
JPS588066A (ja) * 1981-07-03 1983-01-18 Otsuka Pharmaceut Co Ltd 光学活性〔ｓ〕−（−）−カルボスチリル誘導体の製造法
DE3373466D1 (de) * 1982-06-10 1987-10-15 Beecham Wuelfing Gmbh & Co Kg Amine derivatives
DE3519693A1 (de) * 1985-06-01 1987-01-02 Basf Ag Pyridin-derivate, ihre herstellung und verwendung
GB8603475D0 (en) * 1986-02-12 1986-03-19 Glaxo Group Ltd Chemical compounds
GB8703007D0 (en) * 1987-02-10 1987-03-18 Glaxo Group Ltd Chemical compounds
GB9012926D0 (en) * 1990-06-09 1990-08-01 Scras Pyrrolo-pyridine derivatives
ES2173683T3 (es) * 1990-11-30 2002-10-16 Otsuka Pharma Co Ltd Inhibidor del radical superoxido.
MY128323A (en) 1996-09-30 2007-01-31 Otsuka Pharma Co Ltd Thiazole derivatives for inhibition of cytokine production and of cell adhesion
US20010034357A1 (en) * 2000-02-02 2001-10-25 Nan-Horng Lin Substituted pyridine compounds useful for controlling chemical synaptic transmission
CA2521135A1 (en) * 2003-04-07 2004-10-28 Kalypsys, Inc. N-containing heteroaromatic compounds as modulators of ppars and methods of treating metabolic disorders
LT3135672T (lt) * 2008-10-10 2020-05-25 Vm Discovery, Inc. Kompozicijos ir būdai skirti gydyti alkoholio vartojimo sutrikimus, skausmą ir kitas ligas
KR101698153B1 (ko) * 2010-04-26 2017-01-23 광주과학기술원 Ｐ2ｘ1 및 ｐ2ｘ3 수용체 길항제로 사용되는 신규한 피리딘 카르복실산계 화합물, 이의 제조방법 및 이를 포함하는 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1572768A (en) * 1925-06-26 1926-02-09 Winthrop Chem Co Inc Pharmaceutical product
US1881236A (en) * 1929-08-10 1932-10-04 Soc Of Chemical Ind Basic ethers of the pyridine series
US3535328A (en) * 1967-09-01 1970-10-20 Exxon Research Engineering Co Certain substituted aminothioethoxy pyridines
AR207133A1 (es) * 1973-02-20 1976-09-15 Ciba Geigy Ag Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino-propano
US4115575A (en) * 1973-02-20 1978-09-19 Ciba-Geigy Corporation 2-(3-Amino-2-hydroxy-propoxy)-pyrazines
US4073909A (en) * 1973-10-08 1978-02-14 Sandoz Ltd. Isoquinoline compounds
CH591448A5 (nl) 1974-05-14 1977-09-15 Ciba Geigy Ag
CH614711A5 (nl) * 1975-04-08 1979-12-14 Sandoz Ag
GB1504424A (en) * 1975-08-09 1978-03-22 Beecham Group Ltd Isoquinoline-derived aminoethers
GB1485919A (en) 1975-08-12 1977-09-14 Grindstedvaerket As Pyridine derivatives
US4060601A (en) * 1976-06-15 1977-11-29 Merck & Co., Inc. Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines

Also Published As

Publication number Publication date
YU225282A (en) 1983-02-28
FI780842A (fi) 1978-09-18
FR2383930A1 (fr) 1978-10-13
FR2383930B1 (nl) 1982-10-22
YU63678A (en) 1983-01-21
SU850002A3 (ru) 1981-07-23
CA1108148A (en) 1981-09-01
NL189563C (nl) 1993-05-17
CS202012B2 (en) 1980-12-31
BE864917A (fr) 1978-09-15
IT1093796B (it) 1985-07-26
ATA84080A (de) 1981-03-15
DE2711655C2 (nl) 1987-07-16
NL189563B (nl) 1992-12-16
NO150605B (no) 1984-08-06
FI74962C (fi) 1988-04-11
AT364361B (de) 1981-10-12
DD134090A5 (de) 1979-02-07
JPS53116382A (en) 1978-10-11
CH638186A5 (de) 1983-09-15
YU41016B (en) 1986-10-31
AT364360B (de) 1981-10-12
FI74962B (fi) 1987-12-31
CS202011B2 (en) 1980-12-31
IE46484B1 (en) 1983-06-29
ATA187878A (de) 1981-03-15
ES467931A1 (es) 1979-07-01
IL54265A0 (en) 1978-06-15
JPS6123790B2 (nl) 1986-06-07
LU79235A1 (de) 1978-06-28
HU177287B (en) 1981-09-28
US4206117A (en) 1980-06-03
SU799658A3 (ru) 1981-01-23
GB1599061A (en) 1981-09-30
IT7821099A0 (it) 1978-03-10
ZA781552B (en) 1979-04-25
NL7802719A (nl) 1978-09-19
NO780931L (no) 1978-09-19
NO150605C (no) 1984-11-14
SE7802927L (sv) 1978-09-18
IE780503L (en) 1978-09-17
GR64096B (en) 1980-01-22
AU525566B2 (en) 1982-11-11
DE2711655A1 (de) 1978-09-21
AU3419578A (en) 1979-09-20
DK118578A (da) 1978-09-18

Similar Documents

Publication Publication Date Title
SE446185B (sv) Forfarande for framstellning av pyridinylaminoalkyletrar
DK160981B (da) Arylsulfonylurinstof-derivater, fremgangsmaade til fremstilling deraf, anvendelse af disse som terapeutisk og antineoplastisk middel samt farmaceutiske midler indeholdende saadanne derivater
WO2006061379A1 (en) Phenylpiperazine derivatives with a combination of partial dopamine-d2 receptor agonism and serotonin reuptake inhibition
NO324750B1 (no) Substituerte N-benzylindol-3-yl-glyokylinsyrederivater med anti-tumoreffekt, og farmasoytiske preparater som inneholder slike.
JPS59206364A (ja) １−ピリミジニルオキシ−３−ヘテロアリ−ルアルキルアミノ−２−プロパノ−ルおよびその製法と用途
WO2003024937A1 (en) Benzimidazolylalkoxyaryl alkanoic acid derivatives and their use as antihyperglycemics
FI63402B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d- och d1-trans-5-fenyl-2,3,4,4a 5,9b-hexahydro-1h-pyrido(4,3-b)indolderivat
HU190639B (en) Process for production of new aminoguanidin derivatives
US5519025A (en) 4-indolylpiperazinyl derivatives
Nguyen et al. Oxidation of aldehyde semicarbazones with lead dioxide: Application to the syntheses of 2‐amino‐1, 3, 4‐oxadiazoles and 2, 4‐dihydro‐1, 2, 4‐triazol‐3‐ones
Greenwood et al. 2-Aryloxymethyl-2, 3, 5, 6-tetrahydro-1, 4-oxazines, a new class of antidepressants
AU728090B2 (en) Intermediates for the preparation of 2-imidazoline-5-ones
Watanabe et al. Synthesis of novel succinamide derivatives having the 5, 11-dihydro-6H-pyrido [2, 3-b][1, 4] benzodiazepin-6-one skeleton as potent and selective M2 muscarinic receptor antagonists. I
AU598034B2 (en) 1,3-disubstituted imidazolium salts
Klioze et al. Synthesis and antihypertensive activity of 2-benzamido-1, 2, 3, 4, 6, 7, 12, 12b-octahydroindolo [2, 3-a] quinolizines
FI82245B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 5-aminoalkyl- -karbolinderivat.
HU206090B (en) Process for producing new 1-phenyl-1,4-dihydro-3-amino-4-oxopyridazine derivatives and pharmaceutical compositions comprising such compounds as active ingredient
AU7168000A (en) New aminopyrroline compounds, a process for their preparation and pharmaceutical compositions containing them
CN101041636B (zh) 一种合成杂环烯酮缩胺衍生物的方法
US3998842A (en) Diazepino[1,2-α]indoles
US6127362A (en) 9,10-diazatricyclo[4,4,1,12,5 ] decane and 2,7-diazatricyclo [4,4,0,03,8 ] decane derivatives having analgesic activity
SE430692B (sv) Sett att framstella 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl) kinazolinhydroklorid med antihypertensiv verkan
US3373163A (en) N-methyl-piperazides of alicyclic and heterocyclic carboxylic acids
US3141893A (en) 4-amino-coumarins
SE460419B (sv) Substituerade 1-pyridyloxi-3-indolylalkylamino-2-propanoler, foerfarande foer framstaellning av dessa och en farmaceutisk komposition

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7802927-9

Effective date: 19931008

Format of ref document f/p: F