SE446093B - Langkedjiga fettsyraamider och -hydrazider samt cyklopropananaloger derav for anvendning som antiaterosklerotiskt medel samt farmaceutisk komposition - Google Patents
Langkedjiga fettsyraamider och -hydrazider samt cyklopropananaloger derav for anvendning som antiaterosklerotiskt medel samt farmaceutisk kompositionInfo
- Publication number
- SE446093B SE446093B SE7900142A SE7900142A SE446093B SE 446093 B SE446093 B SE 446093B SE 7900142 A SE7900142 A SE 7900142A SE 7900142 A SE7900142 A SE 7900142A SE 446093 B SE446093 B SE 446093B
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- cis
- alkyl
- hydrogen
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B22/00—Use of inorganic materials as active ingredients for mortars, concrete or artificial stone, e.g. accelerators, shrinkage compensating agents
- C04B22/0013—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C243/28—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ceramic Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Vascular Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Materials Engineering (AREA)
- Structural Engineering (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86782478A | 1978-01-09 | 1978-01-09 | |
| US86781378A | 1978-01-09 | 1978-01-09 | |
| US87283678A | 1978-01-27 | 1978-01-27 | |
| US88178178A | 1978-02-27 | 1978-02-27 | |
| US05/881,780 US4229463A (en) | 1978-02-27 | 1978-02-27 | Unsaturated fatty acid hydrazides |
| US05/891,298 US4194002A (en) | 1978-03-29 | 1978-03-29 | Cholesterol ester-reducing amides of hexahydroindolinols |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7900142L SE7900142L (sv) | 1979-07-10 |
| SE446093B true SE446093B (sv) | 1986-08-11 |
Family
ID=27560330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7900142A SE446093B (sv) | 1978-01-09 | 1979-01-08 | Langkedjiga fettsyraamider och -hydrazider samt cyklopropananaloger derav for anvendning som antiaterosklerotiskt medel samt farmaceutisk komposition |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS54109930A (xx) |
| AU (1) | AU529328B2 (xx) |
| CA (1) | CA1101871A (xx) |
| CH (1) | CH644842A5 (xx) |
| CY (1) | CY1294A (xx) |
| DE (1) | DE2856856A1 (xx) |
| DK (1) | DK3079A (xx) |
| FI (1) | FI790025A (xx) |
| FR (1) | FR2416885A1 (xx) |
| GB (1) | GB2012261B (xx) |
| HK (1) | HK80985A (xx) |
| IE (1) | IE48077B1 (xx) |
| IL (1) | IL56393A (xx) |
| IT (1) | IT1110603B (xx) |
| KE (1) | KE3546A (xx) |
| MY (1) | MY8500133A (xx) |
| NZ (1) | NZ189331A (xx) |
| PT (1) | PT69052A (xx) |
| SE (1) | SE446093B (xx) |
| SG (1) | SG42985G (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2937175A1 (de) * | 1978-09-18 | 1980-03-27 | Sandoz Ag | Sekundaere amide von 2-alkynoylsaeuren, deren herstellung und deren pharmazeutischen zusammensetzungen |
| US4297349A (en) | 1980-04-15 | 1981-10-27 | Sandoz, Inc. | Silicon-bearing carboxylic acids and amides |
| US4722927A (en) * | 1986-04-28 | 1988-02-02 | Warner-Lambert Company | Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase |
| FR2633617B1 (fr) * | 1988-07-04 | 1991-02-08 | Adir | Nouveaux derives du benzocycloheptene, leur procede de preparation et les compositions pharmaceutiques les renfermant |
| US5290814A (en) * | 1988-11-21 | 1994-03-01 | Burroughs Wellcome Co. | Anti-atherosclerotic diaryl compounds |
| CN102014897B (zh) * | 2008-04-21 | 2015-08-05 | 西格纳姆生物科学公司 | 化合物、组合物和其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1814334B2 (de) * | 1967-12-21 | 1973-04-19 | Sumitomo Chemical Co Ltd , Osaka (Japan) | Fettsaeureamide und diese verbindungen enthaltende arzneimittel |
| FR2000945A1 (xx) * | 1968-01-30 | 1969-09-19 | Sumitomo Chemical Co | |
| JPS5835505B2 (ja) * | 1976-01-09 | 1983-08-03 | エーザイ株式会社 | Ｎ−（α−メチル−ベンジル）−脂肪酸アミド |
-
1978
- 1978-12-30 DE DE19782856856 patent/DE2856856A1/de not_active Ceased
-
1979
- 1979-01-02 CH CH379A patent/CH644842A5/de not_active IP Right Cessation
- 1979-01-03 DK DK3079A patent/DK3079A/da not_active Application Discontinuation
- 1979-01-04 FI FI790025A patent/FI790025A/fi not_active IP Right Cessation
- 1979-01-04 IT IT19059/79A patent/IT1110603B/it active
- 1979-01-05 GB GB79337A patent/GB2012261B/en not_active Expired
- 1979-01-05 CY CY1294A patent/CY1294A/xx unknown
- 1979-01-08 JP JP13879A patent/JPS54109930A/ja active Granted
- 1979-01-08 NZ NZ189331A patent/NZ189331A/xx unknown
- 1979-01-08 IE IE31/79A patent/IE48077B1/en unknown
- 1979-01-08 IL IL56393A patent/IL56393A/xx unknown
- 1979-01-08 SE SE7900142A patent/SE446093B/sv not_active IP Right Cessation
- 1979-01-08 CA CA319,259A patent/CA1101871A/en not_active Expired
- 1979-01-09 PT PT69052A patent/PT69052A/pt unknown
- 1979-01-09 FR FR7900438A patent/FR2416885A1/fr active Granted
- 1979-01-09 AU AU43233/79A patent/AU529328B2/en not_active Ceased
-
1985
- 1985-06-01 SG SG42985A patent/SG42985G/en unknown
- 1985-06-19 KE KE3546A patent/KE3546A/xx unknown
- 1985-10-17 HK HK809/85A patent/HK80985A/xx unknown
- 1985-12-30 MY MY133/85A patent/MY8500133A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI790025A (fi) | 1979-07-10 |
| FR2416885B1 (xx) | 1983-04-22 |
| PT69052A (fr) | 1979-02-01 |
| FR2416885A1 (fr) | 1979-09-07 |
| GB2012261B (en) | 1982-12-22 |
| CA1101871A (en) | 1981-05-26 |
| IE48077B1 (en) | 1984-09-19 |
| DK3079A (da) | 1979-07-10 |
| IT1110603B (it) | 1985-12-23 |
| IL56393A0 (en) | 1979-03-12 |
| NZ189331A (en) | 1981-07-13 |
| KE3546A (en) | 1985-07-19 |
| CH644842A5 (de) | 1984-08-31 |
| AU4323379A (en) | 1979-07-19 |
| IT7919059A0 (it) | 1979-01-04 |
| IL56393A (en) | 1982-08-31 |
| IE790031L (en) | 1979-07-09 |
| SG42985G (en) | 1985-12-13 |
| MY8500133A (en) | 1985-12-31 |
| SE7900142L (sv) | 1979-07-10 |
| JPS54109930A (en) | 1979-08-29 |
| DE2856856A1 (de) | 1979-07-12 |
| GB2012261A (en) | 1979-07-25 |
| CY1294A (en) | 1985-10-18 |
| AU529328B2 (en) | 1983-06-02 |
| HK80985A (en) | 1985-10-25 |
| JPS6323987B2 (xx) | 1988-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7900142-6 Effective date: 19880915 Format of ref document f/p: F |