IL56393A0 - Amides and hydrazides of ong-chain fatty acids and cyclopropano analogues thereof, their production and pharmaceutical compositions containing them - Google Patents

Amides and hydrazides of ong-chain fatty acids and cyclopropano analogues thereof, their production and pharmaceutical compositions containing them

Info

Publication number
IL56393A0
IL56393A0 IL56393A IL5639379A IL56393A0 IL 56393 A0 IL56393 A0 IL 56393A0 IL 56393 A IL56393 A IL 56393A IL 5639379 A IL5639379 A IL 5639379A IL 56393 A0 IL56393 A0 IL 56393A0
Authority
IL
Israel
Prior art keywords
cyclopropano
ong
hydrazides
analogues
amides
Prior art date
Application number
IL56393A
Other versions
IL56393A (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/881,780 external-priority patent/US4229463A/en
Priority claimed from US05/891,298 external-priority patent/US4194002A/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL56393A0 publication Critical patent/IL56393A0/en
Publication of IL56393A publication Critical patent/IL56393A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04BLIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B22/00Use of inorganic materials as active ingredients for mortars, concrete or artificial stone, e.g. accelerators, shrinkage compensating agents
    • C04B22/0013Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/28Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ceramic Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL56393A 1978-01-09 1979-01-08 Amides of long-chain unsaturated fatty acids and cyclopropano analogues thereof,their production and pharmaceutical compositions containing them IL56393A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US86781378A 1978-01-09 1978-01-09
US86782478A 1978-01-09 1978-01-09
US87283678A 1978-01-27 1978-01-27
US88178178A 1978-02-27 1978-02-27
US05/881,780 US4229463A (en) 1978-02-27 1978-02-27 Unsaturated fatty acid hydrazides
US05/891,298 US4194002A (en) 1978-03-29 1978-03-29 Cholesterol ester-reducing amides of hexahydroindolinols

Publications (2)

Publication Number Publication Date
IL56393A0 true IL56393A0 (en) 1979-03-12
IL56393A IL56393A (en) 1982-08-31

Family

ID=27560330

Family Applications (1)

Application Number Title Priority Date Filing Date
IL56393A IL56393A (en) 1978-01-09 1979-01-08 Amides of long-chain unsaturated fatty acids and cyclopropano analogues thereof,their production and pharmaceutical compositions containing them

Country Status (20)

Country Link
JP (1) JPS54109930A (en)
AU (1) AU529328B2 (en)
CA (1) CA1101871A (en)
CH (1) CH644842A5 (en)
CY (1) CY1294A (en)
DE (1) DE2856856A1 (en)
DK (1) DK3079A (en)
FI (1) FI790025A (en)
FR (1) FR2416885A1 (en)
GB (1) GB2012261B (en)
HK (1) HK80985A (en)
IE (1) IE48077B1 (en)
IL (1) IL56393A (en)
IT (1) IT1110603B (en)
KE (1) KE3546A (en)
MY (1) MY8500133A (en)
NZ (1) NZ189331A (en)
PT (1) PT69052A (en)
SE (1) SE446093B (en)
SG (1) SG42985G (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2937175A1 (en) * 1978-09-18 1980-03-27 Sandoz Ag SECOND AMIDES OF 2-ALKYNOYL ACIDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL COMPOSITIONS
US4297349A (en) 1980-04-15 1981-10-27 Sandoz, Inc. Silicon-bearing carboxylic acids and amides
US4722927A (en) * 1986-04-28 1988-02-02 Warner-Lambert Company Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase
FR2633617B1 (en) * 1988-07-04 1991-02-08 Adir NOVEL BENZOCYCLOHEPTENE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US5290814A (en) * 1988-11-21 1994-03-01 Burroughs Wellcome Co. Anti-atherosclerotic diaryl compounds
EP2282735B1 (en) * 2008-04-21 2019-01-16 Signum Biosciences, Inc. Pp2a modulators for treating alzheimer, parkinson, diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1814334B2 (en) * 1967-12-21 1973-04-19 Sumitomo Chemical Co Ltd , Osaka (Japan) FATTY ACID AMIDES AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
FR2000945A1 (en) * 1968-01-30 1969-09-19 Sumitomo Chemical Co
JPS5835505B2 (en) * 1976-01-09 1983-08-03 エーザイ株式会社 N-(α-methyl-benzyl)-fatty acid amide

Also Published As

Publication number Publication date
IE48077B1 (en) 1984-09-19
NZ189331A (en) 1981-07-13
AU529328B2 (en) 1983-06-02
GB2012261B (en) 1982-12-22
MY8500133A (en) 1985-12-31
SE7900142L (en) 1979-07-10
IL56393A (en) 1982-08-31
HK80985A (en) 1985-10-25
IT7919059A0 (en) 1979-01-04
DK3079A (en) 1979-07-10
FR2416885B1 (en) 1983-04-22
GB2012261A (en) 1979-07-25
JPS54109930A (en) 1979-08-29
FI790025A (en) 1979-07-10
PT69052A (en) 1979-02-01
KE3546A (en) 1985-07-19
CA1101871A (en) 1981-05-26
IE790031L (en) 1979-07-09
CY1294A (en) 1985-10-18
SE446093B (en) 1986-08-11
DE2856856A1 (en) 1979-07-12
FR2416885A1 (en) 1979-09-07
JPS6323987B2 (en) 1988-05-18
SG42985G (en) 1985-12-13
AU4323379A (en) 1979-07-19
CH644842A5 (en) 1984-08-31
IT1110603B (en) 1985-12-23

Similar Documents

Publication Publication Date Title
IL56991A0 (en) 4-halo-3-oxoandrost-4-ene-17 -thiocarboxylic acid esters their preparation and pharmaceutical compositions containing them
PH18091A (en) Novel spiro-oxazolidindiones,pharmaceutical compositions containing same and method of use thereof
IL57662A (en) Acyl-esters of carnitine,process for their preparation and pharmaceutical compositions comprising them
ZA792283B (en) Structural analogs of natural glycerides,process for their preparation and pharmaceutical compositions thereof
GR63213B (en) 4-trifluormethylbenzoic acid derivatives and process of making the same and pharmaceutical compositions containing thereof
MY8700122A (en) N-oxacyclic-alkylpeperidyl-diazacompounds process for their manufacture and pharmaceutical compositions containing them
IL56393A0 (en) Amides and hydrazides of ong-chain fatty acids and cyclopropano analogues thereof, their production and pharmaceutical compositions containing them
IL57215A0 (en) Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof and pharmaceutical compositions containing them
NZ190521A (en) Phenylamino-thiophenacetic acids and pharmaceutical compositions
PH15720A (en) Hypolipidemic derivatives of 4,5-dihydro-4-oxo-furan-2-carboxylic acid,their pharmaceutical compositions and method of use
GB2032423B (en) N - phenyl-indoline derivatives their production and pharmaceutical compositions containing them
IL59002A0 (en) Substituted trifluoroethylamines their production and pharmaceutical compositions containing them
JPS51131888A (en) Production of novel 99 alkylaminooerythromycine and pharmaceutical composition containing same
JPS52136156A (en) Production of novel 177 spirosultine derivatives and corresponding gammaa hydroxylic acid and pharmaceutical composition
IL58384A0 (en) 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them
JPS5531082A (en) Phenoxylactic acid*manufacture and product of derivative thereof
JPS5337651A (en) Production of novel 2*22 dimethyll199norsteroid and pharmaceutical composition
GB2031412B (en) 1-methyl-4-piperidinol esters process for their preparation and pharmaceutical compositions containing them
IL58543A (en) 4,4-dimethyl-4-sila fatty acid amides,their preparation and pharmaceutical compositions containing them
JPS54144381A (en) Novel derivative of 1*33benzodioxine*its manufacture*use as drug and pharmaceutical composition containing it
IL53567A0 (en) Novel derivatives of dithiosalicyclic acid amides their preparation and pharmaceutical compositions containing them
GB1544895A (en) 17-spirosultine derivatives and the corresponding ypsilon-hydroxy acids of estr-3-ones processes for preparing them and pharmaceutical compositions containing them
JPS5214761A (en) Production of 9 alphaa fluorrsteroid and pharmaceutical composition containing the same
IL50166A (en) 7 -(d-2-amino-(1,4-cyclohexadienyl)-acetylamino)-3-hal-3-cephem-4-carboxylic acids their preparation and pharmaceutical compositions containing them
JPS554363A (en) Novel oxime derivative of 33azidomethyll77 aminothiazolylacetamidocephalosporanic acids* their manufacture*their use as drug and pharmaceutic composition containing them