AU529328B2 - Alphatic and cycloaliphatic amides and hydrazides - Google Patents

Alphatic and cycloaliphatic amides and hydrazides

Info

Publication number
AU529328B2
AU529328B2 AU43233/79A AU4323379A AU529328B2 AU 529328 B2 AU529328 B2 AU 529328B2 AU 43233/79 A AU43233/79 A AU 43233/79A AU 4323379 A AU4323379 A AU 4323379A AU 529328 B2 AU529328 B2 AU 529328B2
Authority
AU
Australia
Prior art keywords
alphatic
hydrazides
cycloaliphatic
amides
cycloaliphatic amides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU43233/79A
Other languages
English (en)
Other versions
AU4323379A (en
Inventor
John G. Heider
Faizulla Gulamhusein Kathawala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/881,780 external-priority patent/US4229463A/en
Priority claimed from US05/891,298 external-priority patent/US4194002A/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of AU4323379A publication Critical patent/AU4323379A/en
Application granted granted Critical
Publication of AU529328B2 publication Critical patent/AU529328B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B22/00—Use of inorganic materials as active ingredients for mortars, concrete or artificial stone, e.g. accelerators, shrinkage compensating agents
    • C04B22/0013—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/28—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ceramic Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU43233/79A 1978-01-09 1979-01-09 Alphatic and cycloaliphatic amides and hydrazides Ceased AU529328B2 (en)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US86781378A 1978-01-09 1978-01-09
US86782478A 1978-01-09 1978-01-09
US867813 1978-01-09
US867824 1978-01-09
US87283678A 1978-01-27 1978-01-27
US872836 1978-01-27
US88178178A 1978-02-27 1978-02-27
US881780 1978-02-27
US05/881,780 US4229463A (en) 1978-02-27 1978-02-27 Unsaturated fatty acid hydrazides
US881781 1978-02-27
US05/891,298 US4194002A (en) 1978-03-29 1978-03-29 Cholesterol ester-reducing amides of hexahydroindolinols
US891298 1978-03-29

Publications (2)

Publication Number Publication Date
AU4323379A AU4323379A (en) 1979-07-19
AU529328B2 true AU529328B2 (en) 1983-06-02

Family

ID=27560330

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43233/79A Ceased AU529328B2 (en) 1978-01-09 1979-01-09 Alphatic and cycloaliphatic amides and hydrazides

Country Status (20)

Country Link
JP (1) JPS54109930A (xx)
AU (1) AU529328B2 (xx)
CA (1) CA1101871A (xx)
CH (1) CH644842A5 (xx)
CY (1) CY1294A (xx)
DE (1) DE2856856A1 (xx)
DK (1) DK3079A (xx)
FI (1) FI790025A (xx)
FR (1) FR2416885A1 (xx)
GB (1) GB2012261B (xx)
HK (1) HK80985A (xx)
IE (1) IE48077B1 (xx)
IL (1) IL56393A (xx)
IT (1) IT1110603B (xx)
KE (1) KE3546A (xx)
MY (1) MY8500133A (xx)
NZ (1) NZ189331A (xx)
PT (1) PT69052A (xx)
SE (1) SE446093B (xx)
SG (1) SG42985G (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2937175A1 (de) * 1978-09-18 1980-03-27 Sandoz Ag Sekundaere amide von 2-alkynoylsaeuren, deren herstellung und deren pharmazeutischen zusammensetzungen
US4297349A (en) 1980-04-15 1981-10-27 Sandoz, Inc. Silicon-bearing carboxylic acids and amides
US4722927A (en) * 1986-04-28 1988-02-02 Warner-Lambert Company Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase
FR2633617B1 (fr) * 1988-07-04 1991-02-08 Adir Nouveaux derives du benzocycloheptene, leur procede de preparation et les compositions pharmaceutiques les renfermant
US5290814A (en) * 1988-11-21 1994-03-01 Burroughs Wellcome Co. Anti-atherosclerotic diaryl compounds
EP2282735B1 (en) * 2008-04-21 2019-01-16 Signum Biosciences, Inc. Pp2a modulators for treating alzheimer, parkinson, diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1814334B2 (de) * 1967-12-21 1973-04-19 Sumitomo Chemical Co Ltd , Osaka (Japan) Fettsaeureamide und diese verbindungen enthaltende arzneimittel
FR2000945A1 (xx) * 1968-01-30 1969-09-19 Sumitomo Chemical Co
JPS5835505B2 (ja) * 1976-01-09 1983-08-03 エーザイ株式会社 Ｎ−（α−メチル−ベンジル）−脂肪酸アミド

Also Published As

Publication number Publication date
IE48077B1 (en) 1984-09-19
NZ189331A (en) 1981-07-13
GB2012261B (en) 1982-12-22
MY8500133A (en) 1985-12-31
SE7900142L (sv) 1979-07-10
IL56393A (en) 1982-08-31
HK80985A (en) 1985-10-25
IT7919059A0 (it) 1979-01-04
DK3079A (da) 1979-07-10
FR2416885B1 (xx) 1983-04-22
GB2012261A (en) 1979-07-25
JPS54109930A (en) 1979-08-29
FI790025A (fi) 1979-07-10
PT69052A (fr) 1979-02-01
KE3546A (en) 1985-07-19
CA1101871A (en) 1981-05-26
IE790031L (en) 1979-07-09
CY1294A (en) 1985-10-18
SE446093B (sv) 1986-08-11
DE2856856A1 (de) 1979-07-12
FR2416885A1 (fr) 1979-09-07
IL56393A0 (en) 1979-03-12
JPS6323987B2 (xx) 1988-05-18
SG42985G (en) 1985-12-13
AU4323379A (en) 1979-07-19
CH644842A5 (de) 1984-08-31
IT1110603B (it) 1985-12-23

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