SE440726B - Fast farmaceutisk enhetsdosformkropp innefattande ett laminat - Google Patents
Fast farmaceutisk enhetsdosformkropp innefattande ett laminatInfo
- Publication number
- SE440726B SE440726B SE7906942A SE7906942A SE440726B SE 440726 B SE440726 B SE 440726B SE 7906942 A SE7906942 A SE 7906942A SE 7906942 A SE7906942 A SE 7906942A SE 440726 B SE440726 B SE 440726B
- Authority
- SE
- Sweden
- Prior art keywords
- laminate
- drug
- sheets
- water
- layers
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 claims description 29
- 239000000203 mixture Substances 0.000 claims description 27
- 229920002785 Croscarmellose sodium Polymers 0.000 claims description 19
- 239000003814 drug Substances 0.000 claims description 18
- 229940079593 drug Drugs 0.000 claims description 16
- 239000000835 fiber Substances 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 11
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 7
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 6
- 239000002002 slurry Substances 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 5
- 239000012876 carrier material Substances 0.000 claims 1
- 239000010410 layer Substances 0.000 description 43
- 238000000034 method Methods 0.000 description 11
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- 239000000945 filler Substances 0.000 description 9
- 239000011247 coating layer Substances 0.000 description 7
- 229940105329 carboxymethylcellulose Drugs 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
- 238000000354 decomposition reaction Methods 0.000 description 5
- 230000032798 delamination Effects 0.000 description 5
- 238000007789 sealing Methods 0.000 description 5
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 4
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 4
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 4
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 4
- 240000005589 Calophyllum inophyllum Species 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 239000001913 cellulose Substances 0.000 description 3
- 235000010980 cellulose Nutrition 0.000 description 3
- 230000001427 coherent effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000003607 modifier Substances 0.000 description 3
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 239000004014 plasticizer Substances 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- CDOUZKKFHVEKRI-UHFFFAOYSA-N 3-bromo-n-[(prop-2-enoylamino)methyl]propanamide Chemical compound BrCCC(=O)NCNC(=O)C=C CDOUZKKFHVEKRI-UHFFFAOYSA-N 0.000 description 1
- 229920002799 BoPET Polymers 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 235000010643 Leucaena leucocephala Nutrition 0.000 description 1
- 240000007472 Leucaena leucocephala Species 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- 239000005041 Mylar™ Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- ANTSCNMPPGJYLG-UHFFFAOYSA-N chlordiazepoxide Chemical compound O=N=1CC(NC)=NC2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 ANTSCNMPPGJYLG-UHFFFAOYSA-N 0.000 description 1
- 229960004782 chlordiazepoxide Drugs 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 description 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 235000019329 dioctyl sodium sulphosuccinate Nutrition 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000007688 edging Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000011121 hardwood Substances 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- -1 linen Polymers 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 229940068965 polysorbates Drugs 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 239000011122 softwood Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000004260 weight control Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31971—Of carbohydrate
- Y10T428/31975—Of cellulosic next to another carbohydrate
- Y10T428/31978—Cellulosic next to another cellulosic
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Laminated Bodies (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/935,274 US4180558A (en) | 1978-08-21 | 1978-08-21 | Unit dosage forms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7906942L SE7906942L (sv) | 1980-02-22 |
| SE440726B true SE440726B (sv) | 1985-08-19 |
Family
ID=25466839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7906942A SE440726B (sv) | 1978-08-21 | 1979-08-20 | Fast farmaceutisk enhetsdosformkropp innefattande ett laminat |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4180558A (ja) |
| JP (1) | JPS6038366B2 (ja) |
| AT (1) | AT371708B (ja) |
| AU (1) | AU521053B2 (ja) |
| BE (1) | BE878306R (ja) |
| CA (1) | CA1110168A (ja) |
| DE (1) | DE2932615C2 (ja) |
| DK (1) | DK154186C (ja) |
| FR (1) | FR2433942A2 (ja) |
| GB (1) | GB2028135B (ja) |
| IE (1) | IE48678B1 (ja) |
| IT (1) | IT1123531B (ja) |
| LU (1) | LU81614A1 (ja) |
| NL (1) | NL7906232A (ja) |
| PH (1) | PH15463A (ja) |
| SE (1) | SE440726B (ja) |
| ZA (1) | ZA794240B (ja) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0010987B1 (en) * | 1978-11-07 | 1983-10-05 | Beecham Group Plc | Device for oral administration to a ruminant animal |
| JPS5770816A (en) * | 1980-10-17 | 1982-05-01 | Ono Pharmaceut Co Ltd | Multilayered film preparation of prostagladin of prolonged action |
| US4381780A (en) * | 1981-01-19 | 1983-05-03 | Research Corporation | Sustained release delivery system |
| JPS58134019A (ja) * | 1982-02-05 | 1983-08-10 | Ono Pharmaceut Co Ltd | プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法 |
| JPS5948409A (ja) * | 1982-09-10 | 1984-03-19 | Teikoku Seiyaku Kk | 矯正的歯牙移動促進剤 |
| JPS62186953U (ja) * | 1986-05-19 | 1987-11-27 | ||
| US5451673A (en) * | 1993-04-23 | 1995-09-19 | The United States Of America As Represented By The Secretary Of Agriculture | Films fabricated from mixtures of pectin and starch |
| DE19806966A1 (de) * | 1998-02-19 | 1999-09-09 | Lohmann Therapie Syst Lts | Verfahren und Vorrichtung zum Einbringen einer Vielzahl vereinzelter folienförmiger Darreichungsformen in einen Spender unter Bildung eines viellagigen Stapels |
| JP5759544B2 (ja) | 2010-07-02 | 2015-08-05 | ザ プロクター アンド ギャンブルカンパニー | 活性剤を送達する方法 |
| RU2613316C1 (ru) | 2010-07-02 | 2017-03-15 | Дзе Проктер Энд Гэмбл Компани | Способы доставки медицинского активного агента путем введения индивидуальных медицинских изделий, содержащих филамент |
| CN103025929B (zh) | 2010-07-02 | 2015-11-25 | 宝洁公司 | 包含活性剂的长丝、非织造纤维网和制备它们的方法 |
| WO2012003360A2 (en) | 2010-07-02 | 2012-01-05 | The Procter & Gamble Company | Detergent product and method for making same |
| MX337814B (es) | 2010-07-02 | 2016-03-18 | Procter & Gamble | Procedidmiento para fabricar películas a partir de tramas de tela no tejida. |
| EP2578088A1 (en) | 2011-10-06 | 2013-04-10 | Nestec S.A. | Edible web comprising microorganisms |
| EP3573593B1 (en) | 2017-01-27 | 2023-08-30 | The Procter & Gamble Company | Compositions in the form of dissolvable solid structures |
| CN111542590A (zh) | 2018-01-26 | 2020-08-14 | 宝洁公司 | 包含香料的水溶性单位剂量制品 |
| WO2019147532A1 (en) | 2018-01-26 | 2019-08-01 | The Procter & Gamble Company | Water-soluble unit dose articles comprising perfume |
| CN111492047A (zh) | 2018-01-26 | 2020-08-04 | 宝洁公司 | 水溶性制品以及相关方法 |
| WO2019147533A1 (en) | 2018-01-26 | 2019-08-01 | The Procter & Gamble Company | Water-soluble unit dose articles comprising enzyme |
| WO2019168829A1 (en) | 2018-02-27 | 2019-09-06 | The Procter & Gamble Company | A consumer product comprising a flat package containing unit dose articles |
| US10982176B2 (en) | 2018-07-27 | 2021-04-20 | The Procter & Gamble Company | Process of laundering fabrics using a water-soluble unit dose article |
| US12234431B2 (en) | 2018-10-03 | 2025-02-25 | The Procter & Gamble Company | Water-soluble unit dose articles comprising water-soluble fibrous structures and particles |
| WO2020159860A1 (en) | 2019-01-28 | 2020-08-06 | The Procter & Gamble Company | Recycleable, renewable, or biodegradable package |
| EP3712237A1 (en) | 2019-03-19 | 2020-09-23 | The Procter & Gamble Company | Fibrous water-soluble unit dose articles comprising water-soluble fibrous structures |
| CN113544249A (zh) | 2019-03-19 | 2021-10-22 | 宝洁公司 | 减少织物上的恶臭的方法 |
| BR112021023244A2 (pt) | 2019-06-28 | 2022-01-04 | Procter & Gamble | Artigos fibrosos sólidos dissolvíveis contendo tensoativos aniônicos |
| JP7506249B2 (ja) | 2020-07-31 | 2024-06-25 | ザ プロクター アンド ギャンブル カンパニー | ヘアケア用プリル含有水溶性繊維パウチ |
| CA3189776A1 (en) | 2020-08-19 | 2022-02-24 | The Procter & Gamble Company | Flexible, porous, dissolvable solid sheet article containing direct-added microcapsules and process for making same |
| EP4395730A1 (en) | 2021-08-30 | 2024-07-10 | The Procter & Gamble Company | Dissolvable solid structure comprising first and second polymeric structurants |
| MX2024005474A (es) | 2021-12-17 | 2024-05-22 | Procter & Gamble | Articulos de champu fibroso solido disoluble que contienen sales. |
| EP4489719A1 (en) | 2022-03-10 | 2025-01-15 | The Procter & Gamble Company | Dissolvable solid structure having first and second layers |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4029758A (en) * | 1975-12-15 | 1977-06-14 | Hoffmann-La Roche Inc. | Preparation of pharmaceutical unit dosage forms |
-
1978
- 1978-08-21 US US05/935,274 patent/US4180558A/en not_active Expired - Lifetime
-
1979
- 1979-08-10 DE DE2932615A patent/DE2932615C2/de not_active Expired
- 1979-08-14 ZA ZA00794240A patent/ZA794240B/xx unknown
- 1979-08-14 AU AU49925/79A patent/AU521053B2/en not_active Expired
- 1979-08-15 NL NL7906232A patent/NL7906232A/nl not_active Application Discontinuation
- 1979-08-17 PH PH22921A patent/PH15463A/en unknown
- 1979-08-17 JP JP54104122A patent/JPS6038366B2/ja not_active Expired
- 1979-08-20 DK DK348079A patent/DK154186C/da active
- 1979-08-20 LU LU81614A patent/LU81614A1/de unknown
- 1979-08-20 SE SE7906942A patent/SE440726B/sv not_active IP Right Cessation
- 1979-08-20 BE BE0/196780A patent/BE878306R/fr not_active IP Right Cessation
- 1979-08-20 FR FR7920955A patent/FR2433942A2/fr active Granted
- 1979-08-20 CA CA334,136A patent/CA1110168A/en not_active Expired
- 1979-08-20 AT AT560779A patent/AT371708B/de not_active IP Right Cessation
- 1979-08-20 GB GB7928890A patent/GB2028135B/en not_active Expired
- 1979-08-20 IE IE1590/79A patent/IE48678B1/en unknown
- 1979-08-20 IT IT2517079A patent/IT1123531B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| NL7906232A (nl) | 1980-02-25 |
| DK154186B (da) | 1988-10-24 |
| DE2932615C2 (de) | 1985-06-05 |
| PH15463A (en) | 1983-01-24 |
| GB2028135A (en) | 1980-03-05 |
| DK154186C (da) | 1989-03-13 |
| JPS6038366B2 (ja) | 1985-08-31 |
| IT7925170A0 (it) | 1979-08-20 |
| ZA794240B (en) | 1980-08-27 |
| AT371708B (de) | 1983-07-25 |
| FR2433942A2 (fr) | 1980-03-21 |
| AU521053B2 (en) | 1982-03-11 |
| BE878306R (fr) | 1980-02-20 |
| CA1110168A (en) | 1981-10-06 |
| IE791590L (en) | 1980-02-21 |
| AU4992579A (en) | 1980-02-28 |
| DE2932615A1 (de) | 1980-03-06 |
| ATA560779A (de) | 1982-12-15 |
| LU81614A1 (de) | 1980-09-24 |
| SE7906942L (sv) | 1980-02-22 |
| JPS5528986A (en) | 1980-02-29 |
| IT1123531B (it) | 1986-04-30 |
| IE48678B1 (en) | 1985-04-17 |
| GB2028135B (en) | 1983-03-30 |
| DK348079A (da) | 1980-02-22 |
| US4180558A (en) | 1979-12-25 |
| FR2433942B2 (ja) | 1983-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7906942-3 Effective date: 19910315 Format of ref document f/p: F |