NL7906232A - Vaste, uit een laminaat opgebouwde farmaceutische preparaten. - Google Patents
Vaste, uit een laminaat opgebouwde farmaceutische preparaten. Download PDFInfo
- Publication number
- NL7906232A NL7906232A NL7906232A NL7906232A NL7906232A NL 7906232 A NL7906232 A NL 7906232A NL 7906232 A NL7906232 A NL 7906232A NL 7906232 A NL7906232 A NL 7906232A NL 7906232 A NL7906232 A NL 7906232A
- Authority
- NL
- Netherlands
- Prior art keywords
- laminate
- sheets
- drug
- layers
- paper
- Prior art date
Links
- 239000007787 solid Substances 0.000 title claims description 6
- 239000000825 pharmaceutical preparation Substances 0.000 title description 3
- 239000003814 drug Substances 0.000 claims description 30
- 239000002552 dosage form Substances 0.000 claims description 28
- 239000000203 mixture Substances 0.000 claims description 26
- 229940079593 drug Drugs 0.000 claims description 25
- 229920002785 Croscarmellose sodium Polymers 0.000 claims description 21
- 239000000835 fiber Substances 0.000 claims description 11
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 9
- 239000000725 suspension Substances 0.000 claims description 5
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 4
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 4
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 4
- 230000001476 alcoholic effect Effects 0.000 claims description 3
- 239000010410 layer Substances 0.000 description 41
- 238000000034 method Methods 0.000 description 14
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
- 239000000945 filler Substances 0.000 description 7
- 239000011247 coating layer Substances 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 239000000758 substrate Substances 0.000 description 6
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 5
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 5
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 5
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 5
- 238000007789 sealing Methods 0.000 description 5
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000007884 disintegrant Substances 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 229940105329 carboxymethylcellulose Drugs 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 239000001913 cellulose Substances 0.000 description 3
- 235000010980 cellulose Nutrition 0.000 description 3
- 230000032798 delamination Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000003607 modifier Substances 0.000 description 3
- 229920003043 Cellulose fiber Polymers 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- ANTSCNMPPGJYLG-UHFFFAOYSA-N chlordiazepoxide Chemical compound O=N=1CC(NC)=NC2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 ANTSCNMPPGJYLG-UHFFFAOYSA-N 0.000 description 2
- 229960004782 chlordiazepoxide Drugs 0.000 description 2
- 230000001427 coherent effect Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000003475 lamination Methods 0.000 description 2
- -1 pectin Chemical class 0.000 description 2
- 239000004014 plasticizer Substances 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 241000220479 Acacia Species 0.000 description 1
- 229920002799 BoPET Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- 235000010643 Leucaena leucocephala Nutrition 0.000 description 1
- 241001082241 Lythrum hyssopifolia Species 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- 239000005041 Mylar™ Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 229920002522 Wood fibre Polymers 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000003490 calendering Methods 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000011121 hardwood Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229940068965 polysorbates Drugs 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 239000011122 softwood Substances 0.000 description 1
- 239000007892 solid unit dosage form Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 238000004260 weight control Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31971—Of carbohydrate
- Y10T428/31975—Of cellulosic next to another carbohydrate
- Y10T428/31978—Cellulosic next to another cellulosic
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Laminated Bodies (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93527478 | 1978-08-21 | ||
| US05/935,274 US4180558A (en) | 1978-08-21 | 1978-08-21 | Unit dosage forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7906232A true NL7906232A (nl) | 1980-02-25 |
Family
ID=25466839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7906232A NL7906232A (nl) | 1978-08-21 | 1979-08-15 | Vaste, uit een laminaat opgebouwde farmaceutische preparaten. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4180558A (ja) |
| JP (1) | JPS6038366B2 (ja) |
| AT (1) | AT371708B (ja) |
| AU (1) | AU521053B2 (ja) |
| BE (1) | BE878306R (ja) |
| CA (1) | CA1110168A (ja) |
| DE (1) | DE2932615C2 (ja) |
| DK (1) | DK154186C (ja) |
| FR (1) | FR2433942A2 (ja) |
| GB (1) | GB2028135B (ja) |
| IE (1) | IE48678B1 (ja) |
| IT (1) | IT1123531B (ja) |
| LU (1) | LU81614A1 (ja) |
| NL (1) | NL7906232A (ja) |
| PH (1) | PH15463A (ja) |
| SE (1) | SE440726B (ja) |
| ZA (1) | ZA794240B (ja) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0010987B1 (en) * | 1978-11-07 | 1983-10-05 | Beecham Group Plc | Device for oral administration to a ruminant animal |
| JPS5770816A (en) * | 1980-10-17 | 1982-05-01 | Ono Pharmaceut Co Ltd | Multilayered film preparation of prostagladin of prolonged action |
| US4381780A (en) * | 1981-01-19 | 1983-05-03 | Research Corporation | Sustained release delivery system |
| JPS58134019A (ja) * | 1982-02-05 | 1983-08-10 | Ono Pharmaceut Co Ltd | プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法 |
| JPS5948409A (ja) * | 1982-09-10 | 1984-03-19 | Teikoku Seiyaku Kk | 矯正的歯牙移動促進剤 |
| JPS62186953U (ja) * | 1986-05-19 | 1987-11-27 | ||
| US5451673A (en) * | 1993-04-23 | 1995-09-19 | The United States Of America As Represented By The Secretary Of Agriculture | Films fabricated from mixtures of pectin and starch |
| DE19806966A1 (de) * | 1998-02-19 | 1999-09-09 | Lohmann Therapie Syst Lts | Verfahren und Vorrichtung zum Einbringen einer Vielzahl vereinzelter folienförmiger Darreichungsformen in einen Spender unter Bildung eines viellagigen Stapels |
| JP5759544B2 (ja) | 2010-07-02 | 2015-08-05 | ザ プロクター アンド ギャンブルカンパニー | 活性剤を送達する方法 |
| RU2613316C1 (ru) | 2010-07-02 | 2017-03-15 | Дзе Проктер Энд Гэмбл Компани | Способы доставки медицинского активного агента путем введения индивидуальных медицинских изделий, содержащих филамент |
| CN103025929B (zh) | 2010-07-02 | 2015-11-25 | 宝洁公司 | 包含活性剂的长丝、非织造纤维网和制备它们的方法 |
| WO2012003360A2 (en) | 2010-07-02 | 2012-01-05 | The Procter & Gamble Company | Detergent product and method for making same |
| MX337814B (es) | 2010-07-02 | 2016-03-18 | Procter & Gamble | Procedidmiento para fabricar películas a partir de tramas de tela no tejida. |
| EP2578088A1 (en) | 2011-10-06 | 2013-04-10 | Nestec S.A. | Edible web comprising microorganisms |
| EP3573593B1 (en) | 2017-01-27 | 2023-08-30 | The Procter & Gamble Company | Compositions in the form of dissolvable solid structures |
| CN111542590A (zh) | 2018-01-26 | 2020-08-14 | 宝洁公司 | 包含香料的水溶性单位剂量制品 |
| WO2019147532A1 (en) | 2018-01-26 | 2019-08-01 | The Procter & Gamble Company | Water-soluble unit dose articles comprising perfume |
| CN111492047A (zh) | 2018-01-26 | 2020-08-04 | 宝洁公司 | 水溶性制品以及相关方法 |
| WO2019147533A1 (en) | 2018-01-26 | 2019-08-01 | The Procter & Gamble Company | Water-soluble unit dose articles comprising enzyme |
| WO2019168829A1 (en) | 2018-02-27 | 2019-09-06 | The Procter & Gamble Company | A consumer product comprising a flat package containing unit dose articles |
| US10982176B2 (en) | 2018-07-27 | 2021-04-20 | The Procter & Gamble Company | Process of laundering fabrics using a water-soluble unit dose article |
| US12234431B2 (en) | 2018-10-03 | 2025-02-25 | The Procter & Gamble Company | Water-soluble unit dose articles comprising water-soluble fibrous structures and particles |
| WO2020159860A1 (en) | 2019-01-28 | 2020-08-06 | The Procter & Gamble Company | Recycleable, renewable, or biodegradable package |
| EP3712237A1 (en) | 2019-03-19 | 2020-09-23 | The Procter & Gamble Company | Fibrous water-soluble unit dose articles comprising water-soluble fibrous structures |
| CN113544249A (zh) | 2019-03-19 | 2021-10-22 | 宝洁公司 | 减少织物上的恶臭的方法 |
| BR112021023244A2 (pt) | 2019-06-28 | 2022-01-04 | Procter & Gamble | Artigos fibrosos sólidos dissolvíveis contendo tensoativos aniônicos |
| JP7506249B2 (ja) | 2020-07-31 | 2024-06-25 | ザ プロクター アンド ギャンブル カンパニー | ヘアケア用プリル含有水溶性繊維パウチ |
| CA3189776A1 (en) | 2020-08-19 | 2022-02-24 | The Procter & Gamble Company | Flexible, porous, dissolvable solid sheet article containing direct-added microcapsules and process for making same |
| EP4395730A1 (en) | 2021-08-30 | 2024-07-10 | The Procter & Gamble Company | Dissolvable solid structure comprising first and second polymeric structurants |
| MX2024005474A (es) | 2021-12-17 | 2024-05-22 | Procter & Gamble | Articulos de champu fibroso solido disoluble que contienen sales. |
| EP4489719A1 (en) | 2022-03-10 | 2025-01-15 | The Procter & Gamble Company | Dissolvable solid structure having first and second layers |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4029758A (en) * | 1975-12-15 | 1977-06-14 | Hoffmann-La Roche Inc. | Preparation of pharmaceutical unit dosage forms |
-
1978
- 1978-08-21 US US05/935,274 patent/US4180558A/en not_active Expired - Lifetime
-
1979
- 1979-08-10 DE DE2932615A patent/DE2932615C2/de not_active Expired
- 1979-08-14 ZA ZA00794240A patent/ZA794240B/xx unknown
- 1979-08-14 AU AU49925/79A patent/AU521053B2/en not_active Expired
- 1979-08-15 NL NL7906232A patent/NL7906232A/nl not_active Application Discontinuation
- 1979-08-17 PH PH22921A patent/PH15463A/en unknown
- 1979-08-17 JP JP54104122A patent/JPS6038366B2/ja not_active Expired
- 1979-08-20 DK DK348079A patent/DK154186C/da active
- 1979-08-20 LU LU81614A patent/LU81614A1/de unknown
- 1979-08-20 SE SE7906942A patent/SE440726B/sv not_active IP Right Cessation
- 1979-08-20 BE BE0/196780A patent/BE878306R/fr not_active IP Right Cessation
- 1979-08-20 FR FR7920955A patent/FR2433942A2/fr active Granted
- 1979-08-20 CA CA334,136A patent/CA1110168A/en not_active Expired
- 1979-08-20 AT AT560779A patent/AT371708B/de not_active IP Right Cessation
- 1979-08-20 GB GB7928890A patent/GB2028135B/en not_active Expired
- 1979-08-20 IE IE1590/79A patent/IE48678B1/en unknown
- 1979-08-20 IT IT2517079A patent/IT1123531B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| DK154186B (da) | 1988-10-24 |
| DE2932615C2 (de) | 1985-06-05 |
| PH15463A (en) | 1983-01-24 |
| GB2028135A (en) | 1980-03-05 |
| DK154186C (da) | 1989-03-13 |
| SE440726B (sv) | 1985-08-19 |
| JPS6038366B2 (ja) | 1985-08-31 |
| IT7925170A0 (it) | 1979-08-20 |
| ZA794240B (en) | 1980-08-27 |
| AT371708B (de) | 1983-07-25 |
| FR2433942A2 (fr) | 1980-03-21 |
| AU521053B2 (en) | 1982-03-11 |
| BE878306R (fr) | 1980-02-20 |
| CA1110168A (en) | 1981-10-06 |
| IE791590L (en) | 1980-02-21 |
| AU4992579A (en) | 1980-02-28 |
| DE2932615A1 (de) | 1980-03-06 |
| ATA560779A (de) | 1982-12-15 |
| LU81614A1 (de) | 1980-09-24 |
| SE7906942L (sv) | 1980-02-22 |
| JPS5528986A (en) | 1980-02-29 |
| IT1123531B (it) | 1986-04-30 |
| IE48678B1 (en) | 1985-04-17 |
| GB2028135B (en) | 1983-03-30 |
| DK348079A (da) | 1980-02-22 |
| US4180558A (en) | 1979-12-25 |
| FR2433942B2 (ja) | 1983-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| CNR | Transfer of rights (patent application after its laying open for public inspection) |
Free format text: HOFFMANN-LA ROCHE AG. F. - |
|
| BV | The patent application has lapsed |