SE435997B - Forfarande for framstellning av en stabil losning av ett tetracyklinantibiotikum - Google Patents
Forfarande for framstellning av en stabil losning av ett tetracyklinantibiotikumInfo
- Publication number
- SE435997B SE435997B SE7613959A SE7613959A SE435997B SE 435997 B SE435997 B SE 435997B SE 7613959 A SE7613959 A SE 7613959A SE 7613959 A SE7613959 A SE 7613959A SE 435997 B SE435997 B SE 435997B
- Authority
- SE
- Sweden
- Prior art keywords
- preparing
- procedure
- stable solution
- tetracyclin
- antibiotic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
- A61K31/79—Polymers of vinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyrrole Compounds (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX604076A MX154913A (es) | 1976-01-02 | 1976-12-17 | Procedimiento para preparar soluciones acuosas de tetraciclina en 2-pirrolidona |
MX603876A MX155081A (es) | 1976-01-02 | 1976-12-17 | Procedimiento para preparar soluciones acuosas de doxiciclima en 2-pirrolidona |
MX524476U MX6648E (es) | 1976-01-02 | 1976-12-17 | Procedimiento para preparar soluciones acuosas de oxitetraciclina,en 2-pirrolidona |
MX603976A MX155116A (es) | 1976-01-02 | 1976-12-17 | Procedimiento para preparar soluciones acuosas de clorotetraciclina en 2-pirrolidona |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/646,295 US4018889A (en) | 1976-01-02 | 1976-01-02 | Oxytetracycline compositions |
CA268,177A CA1075603A (en) | 1976-01-02 | 1976-12-17 | Stable solutions of doxycycline in aqueous 2-pyrrolidone |
KR7700012A KR810000900B1 (ko) | 1976-01-02 | 1977-01-06 | 항생물질 조성제의 안정화 방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7613959L SE7613959L (sv) | 1977-07-03 |
SE435997B true SE435997B (sv) | 1984-11-05 |
Family
ID=27164830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7613959A SE435997B (sv) | 1976-01-02 | 1976-12-10 | Forfarande for framstellning av en stabil losning av ett tetracyklinantibiotikum |
Country Status (29)
Country | Link |
---|---|
US (3) | US4018889A (pt) |
JP (1) | JPS5290616A (pt) |
KR (1) | KR810000900B1 (pt) |
AR (1) | AR209242A1 (pt) |
AT (1) | AT345977B (pt) |
BE (1) | BE849885A (pt) |
BG (1) | BG36493A3 (pt) |
CA (2) | CA1075603A (pt) |
CH (1) | CH616080A5 (pt) |
CS (1) | CS205030B2 (pt) |
DD (1) | DD129997A5 (pt) |
DE (1) | DE2659152C2 (pt) |
DK (1) | DK145753C (pt) |
EG (1) | EG12291A (pt) |
FI (1) | FI56116C (pt) |
FR (1) | FR2336937A1 (pt) |
GB (1) | GB1520197A (pt) |
GR (1) | GR65305B (pt) |
HK (1) | HK30181A (pt) |
IE (1) | IE44767B1 (pt) |
IN (1) | IN145845B (pt) |
KE (1) | KE3166A (pt) |
LU (1) | LU76493A1 (pt) |
NL (1) | NL166620C (pt) |
OA (1) | OA05524A (pt) |
PT (1) | PT66017B (pt) |
SE (1) | SE435997B (pt) |
SU (1) | SU1309901A3 (pt) |
ZA (1) | ZA767689B (pt) |
Families Citing this family (102)
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US4126680A (en) * | 1977-04-27 | 1978-11-21 | Pfizer Inc. | Tetracycline antibiotic compositions |
DE2963584D1 (en) * | 1978-08-01 | 1982-10-21 | Ciba Geigy Ag | Stable, liquid pharmaceutical formulation, its preparation and use |
EP0012496B1 (en) * | 1978-12-08 | 1983-07-20 | Beecham Group Plc | A process for the preparation of a solid sodium amoxycillin and aqueous solutions thereof |
US4259331A (en) * | 1979-04-16 | 1981-03-31 | Pfizer Inc. | Oxytetracycline compositions |
IE49934B1 (en) * | 1979-07-02 | 1986-01-08 | Pfizer | Long acting sulfonamide injectable compositions |
IE49933B1 (en) * | 1979-07-05 | 1986-01-08 | Pfizer | Sulfonamide solutions |
US4303643A (en) * | 1979-07-05 | 1981-12-01 | Pfizer Inc. | Sulfonamide compositions |
US4386083A (en) * | 1980-04-10 | 1983-05-31 | Walter Hacke | Injectable oxytetracycline compositions |
US4399127A (en) * | 1980-04-10 | 1983-08-16 | Diamond Shamrock Corporation | Injectable oxytetracycline compositions |
CA1163197A (en) * | 1980-04-10 | 1984-03-06 | Herman Horn | Injectable oxytetracycline compositions |
US4374826A (en) * | 1980-07-21 | 1983-02-22 | Pfizer Inc. | Sulfonamide compositions |
NL178941C (nl) * | 1982-06-15 | 1986-06-16 | Aesculaap Bv | Werkwijze voor de bereiding van een waterig oxytetracyclinepreparaat. |
US4769232A (en) * | 1984-03-22 | 1988-09-06 | Pfizer Inc. | Parenteral formulations of indolmycin |
IE74244B1 (en) * | 1985-10-01 | 1997-07-16 | Bimeda Res Dev Ltd | A process for preparing an antibiotic composition |
HU194493B (en) * | 1985-11-27 | 1988-02-29 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing primycin-containing colloidal basic gel and compositions comprising the same |
FR2608044B1 (fr) * | 1986-12-10 | 1992-09-11 | Sogeval | Composition antibiotique aqueuse a usage veterinaire |
US4906475A (en) * | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
US6756365B2 (en) * | 1991-11-06 | 2004-06-29 | Trustees Of Tufts College | Reducing tetracycline resistance in living cells |
EP0626171A1 (de) * | 1993-05-26 | 1994-11-30 | Winfried Dörnhöfer | Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere |
ES2130069B1 (es) * | 1997-04-10 | 2000-03-01 | Basf Labiana S A | Preparacion farmaceutica con liberacion retardada del producto activo. |
US20020077276A1 (en) * | 1999-04-27 | 2002-06-20 | Fredeking Terry M. | Compositions and methods for treating hemorrhagic virus infections and other disorders |
US6849615B2 (en) | 1999-09-14 | 2005-02-01 | Paratek Pharmaceuticals, Inc. | 13-substituted methacycline compounds |
CA2672722C (en) | 1999-09-14 | 2013-11-05 | Trustees Of Tufts College | Methods of preparing substituted tetracyclines with transition metal-based chemistries |
US8106225B2 (en) * | 1999-09-14 | 2012-01-31 | Trustees Of Tufts College | Methods of preparing substituted tetracyclines with transition metal-based chemistries |
US6500812B2 (en) | 1999-09-14 | 2002-12-31 | Paratek Pharmaceuticals, Inc. | 13-substituted methacycline compounds |
WO2001051089A1 (de) * | 2000-01-13 | 2001-07-19 | Merck Patent Gmbh | Pharmazeutische zubereitungen enthaltend 2-pyrrolidon als lösungsvermittler |
US6833365B2 (en) | 2000-01-24 | 2004-12-21 | Trustees Of Tufts College | Tetracycline compounds for treatment of Cryptosporidium parvum related disorders |
CN1430600A (zh) * | 2000-03-31 | 2003-07-16 | 塔夫茨大学信托人 | 7-和9-氨基甲酸酯、脲、硫脲、硫代氨基甲酸酯,和杂芳基-氨基取代的四环素化合物 |
DE60102815D1 (de) | 2000-05-15 | 2004-05-19 | Paratek Pharm Innc | 7-substituierte kondensierte ring-tetrazyclin- verbindungen |
US20020132798A1 (en) * | 2000-06-16 | 2002-09-19 | Nelson Mark L. | 7-phenyl-substituted tetracycline compounds |
US20040224927A1 (en) * | 2000-06-16 | 2004-11-11 | Trustees Of Tufts College | 7-N-substituted phenyl tetracycline compounds |
AU2001268475A1 (en) * | 2000-06-16 | 2002-01-02 | Trustees Of Tufts College | 7-phenyl-substituted tetracycline compounds |
US7094806B2 (en) * | 2000-07-07 | 2006-08-22 | Trustees Of Tufts College | 7, 8 and 9-substituted tetracycline compounds |
KR100674047B1 (ko) | 2000-07-07 | 2007-01-25 | 트러스티즈 오브 터프츠 칼리지 | 9-치환된 미노사이클린 화합물 |
US20050143353A1 (en) * | 2000-07-07 | 2005-06-30 | Paratek Pharmaceuticals, Inc. | 13-Substituted methacycline compounds |
EA200300136A1 (ru) | 2000-07-07 | 2003-06-26 | Трастис Оф Тафтс Коллидж | 13-замещенное соединение метациклина (варианты) и способ его получения (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния млекопитающего |
ATE504562T1 (de) | 2000-07-07 | 2011-04-15 | Tufts College | 7-, 8- und 9-substitutierte tetracyclinverbindungen |
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US7553828B2 (en) | 2001-03-13 | 2009-06-30 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl substituted minocycline compounds |
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US2987437A (en) * | 1958-03-06 | 1961-06-06 | Gen Aniline & Film Corp | Nematocidal composition |
US3062717A (en) * | 1958-12-11 | 1962-11-06 | Pfizer & Co C | Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation |
US3957972A (en) * | 1966-05-31 | 1976-05-18 | Koninklijke Nederlandsche Gist-En Spiritusfabriek N.V. | Stable solutions of oxytetracycline suitable for parenteral and peroral administration and process of preparation |
NL6607516A (pt) * | 1966-05-31 | 1967-12-01 | ||
DE1767891C3 (de) * | 1968-06-28 | 1980-10-30 | Pfizer | Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat |
US3957980A (en) * | 1972-10-26 | 1976-05-18 | Pfizer Inc. | Doxycycline parenteral compositions |
GB1508601A (en) * | 1974-01-19 | 1978-04-26 | Norbrook Labor Ltd | Oxytetracycline solution |
DK138974B (da) * | 1974-02-19 | 1978-11-27 | Ciba Geigy Ag | Fremgangsmåde til fremstilling af vandige oxytetracyclinopløsninger til parenteral, peroral og lokal anvendelse. |
US3957994A (en) * | 1974-12-19 | 1976-05-18 | Nelson Research & Development Company | Topical anti-inflammatory composition and method of use |
US3932653A (en) * | 1974-12-19 | 1976-01-13 | Nelson Research & Development Co. | Composition and method for topical administration of griseofulvin |
US3969516A (en) * | 1974-12-19 | 1976-07-13 | Nelson Research & Development Company | Composition and method for treatment of acne |
GB1538903A (en) | 1975-04-11 | 1979-01-24 | Nelson Res & Dev | Carrier for a topically applied physiologically active agent or cosmetic agent |
-
1976
- 1976-01-02 US US05/646,295 patent/US4018889A/en not_active Expired - Lifetime
- 1976-12-07 US US05/748,355 patent/US4081528A/en not_active Expired - Lifetime
- 1976-12-07 US US05/748,600 patent/US4086332A/en not_active Expired - Lifetime
- 1976-12-10 SE SE7613959A patent/SE435997B/xx not_active IP Right Cessation
- 1976-12-15 GB GB52394/76A patent/GB1520197A/en not_active Expired
- 1976-12-15 IN IN2209/CAL/76A patent/IN145845B/en unknown
- 1976-12-17 CA CA268,177A patent/CA1075603A/en not_active Expired
- 1976-12-21 IE IE2800/76A patent/IE44767B1/en not_active IP Right Cessation
- 1976-12-23 GR GR52477A patent/GR65305B/el unknown
- 1976-12-23 CA CA268,611A patent/CA1072012A/en not_active Expired
- 1976-12-24 JP JP15613476A patent/JPS5290616A/ja active Granted
- 1976-12-27 PT PT66017A patent/PT66017B/pt unknown
- 1976-12-28 DK DK584676A patent/DK145753C/da not_active IP Right Cessation
- 1976-12-28 EG EG800/76A patent/EG12291A/xx active
- 1976-12-28 DE DE2659152A patent/DE2659152C2/de not_active Expired
- 1976-12-28 BE BE1007849A patent/BE849885A/xx not_active IP Right Cessation
- 1976-12-28 NL NL7614470.A patent/NL166620C/xx not_active IP Right Cessation
- 1976-12-28 CH CH1640076A patent/CH616080A5/fr not_active IP Right Cessation
- 1976-12-28 SU SU762436954A patent/SU1309901A3/ru active
- 1976-12-28 AT AT971776A patent/AT345977B/de active
- 1976-12-28 FI FI763716A patent/FI56116C/fi not_active IP Right Cessation
- 1976-12-29 ZA ZA767689A patent/ZA767689B/xx unknown
- 1976-12-29 LU LU76493A patent/LU76493A1/xx unknown
- 1976-12-29 CS CS768758A patent/CS205030B2/cs unknown
- 1976-12-29 AR AR266034A patent/AR209242A1/es active
- 1976-12-29 OA OA56026A patent/OA05524A/xx unknown
- 1976-12-29 FR FR7639413A patent/FR2336937A1/fr active Granted
- 1976-12-29 BG BG035054A patent/BG36493A3/xx not_active Expired
- 1976-12-29 DD DD7600196699A patent/DD129997A5/xx unknown
-
1977
- 1977-01-06 KR KR7700012A patent/KR810000900B1/ko not_active IP Right Cessation
-
1981
- 1981-07-02 HK HK301/81A patent/HK30181A/xx unknown
- 1981-10-15 KE KE3166A patent/KE3166A/xx unknown
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