SE433935B - Sett att framstella nya aryloxiaminobutanoler, stereoisomerer och ogiftiga syraadditionssalter derav - Google Patents

Sett att framstella nya aryloxiaminobutanoler, stereoisomerer och ogiftiga syraadditionssalter derav

Info

Publication number
SE433935B
SE433935B SE7501801A SE7501801A SE433935B SE 433935 B SE433935 B SE 433935B SE 7501801 A SE7501801 A SE 7501801A SE 7501801 A SE7501801 A SE 7501801A SE 433935 B SE433935 B SE 433935B
Authority
SE
Sweden
Prior art keywords
compounds
general formula
stereoisomers
acid addition
addition salts
Prior art date
Application number
SE7501801A
Other languages
English (en)
Swedish (sv)
Other versions
SE7501801L (e
Inventor
K Harsanyi
D Korbonits
E Molnar
J Szegi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of SE7501801L publication Critical patent/SE7501801L/xx
Publication of SE433935B publication Critical patent/SE433935B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7501801A 1974-02-20 1975-02-18 Sett att framstella nya aryloxiaminobutanoler, stereoisomerer och ogiftiga syraadditionssalter derav SE433935B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI1449A HU169464B (e) 1974-02-20 1974-02-20

Publications (2)

Publication Number Publication Date
SE7501801L SE7501801L (e) 1975-08-21
SE433935B true SE433935B (sv) 1984-06-25

Family

ID=10994508

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7501801A SE433935B (sv) 1974-02-20 1975-02-18 Sett att framstella nya aryloxiaminobutanoler, stereoisomerer och ogiftiga syraadditionssalter derav

Country Status (22)

Country Link
JP (1) JPS5929063B2 (e)
AT (1) AT339281B (e)
BE (1) BE825745A (e)
BG (2) BG26366A3 (e)
CA (1) CA1074338A (e)
CH (1) CH619684A5 (e)
CS (1) CS199578B2 (e)
DD (1) DD119414A5 (e)
DE (1) DE2506355C2 (e)
DK (1) DK141935B (e)
ES (2) ES434784A1 (e)
FI (1) FI61304C (e)
FR (1) FR2261001B1 (e)
GB (1) GB1457086A (e)
HU (1) HU169464B (e)
IL (1) IL46634A (e)
NL (1) NL182698C (e)
NO (1) NO141754C (e)
PL (2) PL99025B1 (e)
SE (1) SE433935B (e)
SU (1) SU1025327A3 (e)
YU (2) YU36916B (e)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48309A (en) * 1974-10-25 1980-01-31 Robins Co Inc A H 1-aryloxy-4-amino-2-butanols and pharmaceutical compositions containing them
EP0097000B1 (en) * 1982-06-10 1987-09-09 Beecham Wuelfing GmbH & Co KG Amine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1957706C3 (de) * 1968-11-18 1978-06-29 Pfizer Corp., Colon (Panama) Kernsubstituierte 3-Phenoxy-l-phenoxyalkylamino-propan-2-ole und Arzneimittel auf deren Basis
GB1245148A (en) * 1968-11-18 1971-09-08 Pfizer Ltd Propanolamine derivatives
SE384853B (sv) * 1972-04-04 1976-05-24 Haessle Ab Forfarande for framstellning av nya aminer
CH556818A (de) * 1969-09-24 1974-12-13 Ici Ltd Verfahren zur herstellung von alkanolaminderivaten.

Also Published As

Publication number Publication date
YU167681A (en) 1983-04-27
FR2261001B1 (e) 1978-07-21
FR2261001A1 (e) 1975-09-12
IL46634A (en) 1979-01-31
JPS5929063B2 (ja) 1984-07-18
CH619684A5 (en) 1980-10-15
CA1074338A (en) 1980-03-25
IL46634A0 (en) 1975-04-25
JPS50117728A (e) 1975-09-16
SU1025327A3 (ru) 1983-06-23
ATA114075A (de) 1977-02-15
SE7501801L (e) 1975-08-21
DD119414A5 (e) 1976-04-20
FI61304C (fi) 1982-07-12
NO141754B (no) 1980-01-28
DK141935C (e) 1980-12-08
BG26367A4 (bg) 1979-03-15
ES453326A1 (es) 1977-11-16
PL99023B1 (pl) 1978-06-30
NO141754C (no) 1980-05-07
YU37116B (en) 1984-08-31
NO750566L (e) 1975-08-21
CS199578B2 (en) 1980-07-31
HU169464B (e) 1976-11-28
ES434784A1 (es) 1977-03-16
DK141935B (da) 1980-07-21
BG26366A3 (bg) 1979-03-15
FI750443A (e) 1975-08-21
DK60875A (e) 1975-10-20
NL7501951A (nl) 1975-08-22
FI61304B (fi) 1982-03-31
BE825745A (fr) 1975-06-16
NL182698C (nl) 1988-05-02
DE2506355C2 (de) 1983-10-06
PL99025B1 (pl) 1978-06-30
DE2506355A1 (de) 1975-08-21
YU37375A (en) 1982-06-18
YU36916B (en) 1984-08-31
GB1457086A (en) 1976-12-01
AT339281B (de) 1977-10-10

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