SE431871B - Forfarande for framstellning av 2-brom-6-fluor-n-2-imidazolidinylidenbensamin - Google Patents

Forfarande for framstellning av 2-brom-6-fluor-n-2-imidazolidinylidenbensamin

Info

Publication number
SE431871B
SE431871B SE7707689A SE7707689A SE431871B SE 431871 B SE431871 B SE 431871B SE 7707689 A SE7707689 A SE 7707689A SE 7707689 A SE7707689 A SE 7707689A SE 431871 B SE431871 B SE 431871B
Authority
SE
Sweden
Prior art keywords
imidazolidinylideenbenamine
bromo
fluoro
preparing
procedure
Prior art date
Application number
SE7707689A
Other languages
English (en)
Swedish (sv)
Other versions
SE7707689L (sv
Inventor
H Stehle
H Koppe
W Kummer
W Hoefke
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of SE7707689L publication Critical patent/SE7707689L/xx
Publication of SE431871B publication Critical patent/SE431871B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/50Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electric Clocks (AREA)
SE7707689A 1976-07-03 1977-07-01 Forfarande for framstellning av 2-brom-6-fluor-n-2-imidazolidinylidenbensamin SE431871B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2630060A DE2630060C2 (de) 1976-07-03 1976-07-03 2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung

Publications (2)

Publication Number Publication Date
SE7707689L SE7707689L (sv) 1978-01-04
SE431871B true SE431871B (sv) 1984-03-05

Family

ID=5982175

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7707689A SE431871B (sv) 1976-07-03 1977-07-01 Forfarande for framstellning av 2-brom-6-fluor-n-2-imidazolidinylidenbensamin

Country Status (32)

Country Link
US (1) US4166859A (cs)
JP (1) JPS6026108B2 (cs)
AT (1) AT354436B (cs)
AU (1) AU507260B2 (cs)
BE (1) BE856395A (cs)
BG (1) BG28049A3 (cs)
CA (1) CA1088550A (cs)
CH (2) CH633273A5 (cs)
CS (1) CS204005B2 (cs)
DD (1) DD132965A5 (cs)
DE (1) DE2630060C2 (cs)
DK (1) DK146281C (cs)
ES (4) ES460351A1 (cs)
FI (1) FI64146C (cs)
FR (1) FR2356642B1 (cs)
GB (1) GB1575147A (cs)
GR (1) GR63636B (cs)
HU (1) HU180429B (cs)
IE (1) IE45109B1 (cs)
IL (1) IL52433A (cs)
LU (1) LU77679A1 (cs)
MX (1) MX4841E (cs)
NL (2) NL188643C (cs)
NO (2) NO145951C (cs)
NZ (1) NZ184539A (cs)
PH (1) PH14572A (cs)
PL (1) PL102918B1 (cs)
PT (1) PT66756B (cs)
SE (1) SE431871B (cs)
SU (2) SU680644A3 (cs)
YU (1) YU161977A (cs)
ZA (1) ZA773979B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2806811A1 (de) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben
DE2806775A1 (de) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
US4644007A (en) * 1981-11-20 1987-02-17 Alcon Laboratories, Inc. 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
US4515800A (en) * 1981-11-20 1985-05-07 Icilio Cavero Method of lowering intraocular pressure using phenylimino-imidazoles
US4517199A (en) * 1981-11-20 1985-05-14 Alcon Laboratories, Inc. Method for lowering intraocular pressure using phenylimino-imidazoles
US4461904A (en) * 1981-11-20 1984-07-24 Alcon Laboratories, Inc. 2-(Trisubstituted phenylimino)-imidazolines
DE3437694A1 (de) * 1984-10-15 1986-04-17 Boehringer Ingelheim Vetmedica GmbH, 6507 Ingelheim Verwendung einer substanz als sedativum
US4587257A (en) * 1984-12-14 1986-05-06 Alcon Laboratories, Inc. Control of ocular bleeding using clonidine derivatives
JPH0317363Y2 (cs) * 1986-11-19 1991-04-12
US5441339A (en) * 1992-10-22 1995-08-15 Prince Corporation Vehicle light
WO2005000818A1 (en) 2003-06-27 2005-01-06 Warner-Lambert Company Llc 5-substituted-4-`(substituted phenyl)!amino!-2-pyridone deviatives for use as mek inhibitors
CN115784896A (zh) * 2022-11-24 2023-03-14 山东诚创蓝海医药科技有限公司 一种2-溴-6-氟苯胺的制备方法
CN116063184A (zh) * 2022-12-28 2023-05-05 浙江车头制药股份有限公司 一种2-溴-6-氟苯胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770874B2 (de) * 1968-07-12 1977-09-15 Veb Arzneimittelwerk Dresden, Ddr 8122 Radebeul Verfahren zur herstellung von 2-(2,6- dichlorphenylamino)-imidazolin-2
BE787683A (fr) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-phenylimino-imidazolidines, leurs sels d'addition avec des acides et procedes pour les fabriquer
DE2446758C3 (de) * 1974-10-01 1979-01-04 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie
DE2542702C2 (de) * 1975-09-25 1983-11-10 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Verfahren zur Herstellung von 1-Benzoyl-2-(2,6-dichlorphenylamino)-2-imidazolin

Also Published As

Publication number Publication date
BE856395A (fr) 1978-01-02
NO1994024I1 (no) 1994-11-25
JPS535164A (en) 1978-01-18
CH633275A5 (de) 1982-11-30
JPS6026108B2 (ja) 1985-06-21
DD132965A5 (de) 1978-11-22
ZA773979B (en) 1979-03-28
YU161977A (en) 1983-01-21
IE45109B1 (en) 1982-06-16
PT66756B (de) 1979-06-07
GB1575147A (en) 1980-09-17
CS204005B2 (en) 1981-03-31
US4166859A (en) 1979-09-04
PL102918B1 (pl) 1979-05-31
ES466850A1 (es) 1978-10-01
NL188643C (nl) 1992-08-17
NL7707308A (nl) 1978-01-05
DK146281C (da) 1984-01-30
ES466851A1 (es) 1978-10-01
FI64146B (fi) 1983-06-30
AT354436B (de) 1979-01-10
FR2356642A1 (fr) 1978-01-27
NL188643B (nl) 1992-03-16
LU77679A1 (cs) 1978-09-14
CA1088550A (en) 1980-10-28
NO145951C (no) 1982-06-30
CH633273A5 (de) 1982-11-30
HU180429B (en) 1983-03-28
DK146281B (da) 1983-08-22
MX4841E (es) 1982-10-28
DK296477A (da) 1978-01-04
FI771972A (cs) 1978-01-04
ATA438777A (de) 1979-06-15
NL930111I1 (nl) 1993-10-18
FR2356642B1 (fr) 1985-07-19
NO772329L (no) 1978-01-03
FI64146C (fi) 1983-10-10
ES460351A1 (es) 1978-08-16
BG28049A3 (en) 1980-02-25
NL930111I2 (nl) 1995-04-03
GR63636B (en) 1979-11-27
PL199298A1 (pl) 1978-03-28
IL52433A0 (en) 1977-10-31
IE45109L (en) 1978-01-03
NZ184539A (en) 1980-03-05
DE2630060C2 (de) 1984-04-19
SE7707689L (sv) 1978-01-04
AU507260B2 (en) 1980-02-07
AU2662077A (en) 1979-01-04
PT66756A (de) 1977-08-01
IL52433A (en) 1980-09-16
NO145951B (no) 1982-03-22
SU665800A3 (ru) 1979-05-30
DE2630060A1 (de) 1978-01-12
SU680644A3 (ru) 1979-08-15
PH14572A (en) 1981-09-24
ES466852A1 (es) 1978-10-01

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