SE423903B - Forfarande for framstellning av 9 alfa, 21-dihalogen-11 beta,17 alfa-dihydroxi-6 alfa-flour-16 alfa-metyl-pregna-1,4-dien-3,20-dion-estrar - Google Patents
Forfarande for framstellning av 9 alfa, 21-dihalogen-11 beta,17 alfa-dihydroxi-6 alfa-flour-16 alfa-metyl-pregna-1,4-dien-3,20-dion-estrarInfo
- Publication number
- SE423903B SE423903B SE7613920A SE7613920A SE423903B SE 423903 B SE423903 B SE 423903B SE 7613920 A SE7613920 A SE 7613920A SE 7613920 A SE7613920 A SE 7613920A SE 423903 B SE423903 B SE 423903B
- Authority
- SE
- Sweden
- Prior art keywords
- alfa
- dione
- dihydroxy
- diene
- beta
- Prior art date
Links
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 229910052731 fluorine Chemical group 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1615175A CH621801A5 (en) | 1975-12-12 | 1975-12-12 | Process for the preparation of polyhalosteroids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7613920L SE7613920L (sv) | 1977-06-13 |
| SE423903B true SE423903B (sv) | 1982-06-14 |
Family
ID=4414846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7613920A SE423903B (sv) | 1975-12-12 | 1976-12-10 | Forfarande for framstellning av 9 alfa, 21-dihalogen-11 beta,17 alfa-dihydroxi-6 alfa-flour-16 alfa-metyl-pregna-1,4-dien-3,20-dion-estrar |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE849268A (de) |
| CH (4) | CH621801A5 (de) |
| SE (1) | SE423903B (de) |
| ZA (1) | ZA767382B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118271385B (zh) * | 2024-04-01 | 2025-02-14 | 湖南玉新药业有限公司 | 卤倍他索丙酸酯粗品的精制方法 |
-
1975
- 1975-12-12 CH CH1615175A patent/CH621801A5/de not_active IP Right Cessation
-
1976
- 1976-12-10 SE SE7613920A patent/SE423903B/xx not_active IP Right Cessation
- 1976-12-10 BE BE173138A patent/BE849268A/xx not_active IP Right Cessation
- 1976-12-10 ZA ZA767382A patent/ZA767382B/xx unknown
-
1979
- 1979-09-18 CH CH841679A patent/CH622271A5/de not_active IP Right Cessation
- 1979-09-18 CH CH841579A patent/CH622270A5/de not_active IP Right Cessation
- 1979-09-18 CH CH841479A patent/CH621802A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA767382B (en) | 1977-11-30 |
| CH622271A5 (en) | 1981-03-31 |
| BE849268A (fr) | 1977-06-10 |
| SE7613920L (sv) | 1977-06-13 |
| CH622270A5 (en) | 1981-03-31 |
| CH621802A5 (en) | 1981-02-27 |
| CH621801A5 (en) | 1981-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
Ref document number: 7613920-3 Format of ref document f/p: F |
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| NUG | Patent has lapsed |
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