SE405856B - Forfarande for framstellning av 8-alkyl-5-oxo-2-piperazino-5,8-dihydro-pyrido(2,3-d)pyrimidin-6-karbonsyror - Google Patents

Forfarande for framstellning av 8-alkyl-5-oxo-2-piperazino-5,8-dihydro-pyrido(2,3-d)pyrimidin-6-karbonsyror

Info

Publication number
SE405856B
SE405856B SE7310615A SE7310615A SE405856B SE 405856 B SE405856 B SE 405856B SE 7310615 A SE7310615 A SE 7310615A SE 7310615 A SE7310615 A SE 7310615A SE 405856 B SE405856 B SE 405856B
Authority
SE
Sweden
Prior art keywords
oxo
pyrimidine
formula
solution
dihydropyrido
Prior art date
Application number
SE7310615A
Other languages
English (en)
Swedish (sv)
Inventor
M Pesson
Original Assignee
Bellon Labor Sa Roger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bellon Labor Sa Roger filed Critical Bellon Labor Sa Roger
Publication of SE405856B publication Critical patent/SE405856B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE7310615A 1972-08-02 1973-08-01 Forfarande for framstellning av 8-alkyl-5-oxo-2-piperazino-5,8-dihydro-pyrido(2,3-d)pyrimidin-6-karbonsyror SE405856B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7227876A FR2194420B1 (xx) 1972-08-02 1972-08-02

Publications (1)

Publication Number Publication Date
SE405856B true SE405856B (sv) 1979-01-08

Family

ID=9102758

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7310615A SE405856B (sv) 1972-08-02 1973-08-01 Forfarande for framstellning av 8-alkyl-5-oxo-2-piperazino-5,8-dihydro-pyrido(2,3-d)pyrimidin-6-karbonsyror

Country Status (22)

Country Link
US (1) US3950338A (xx)
JP (5) JPS5245719B2 (xx)
BE (1) BE802860A (xx)
CA (1) CA1074793A (xx)
CH (1) CH580100A5 (xx)
CS (1) CS212738B2 (xx)
DD (1) DD107282A5 (xx)
DE (1) DE2338325C2 (xx)
DK (1) DK152731C (xx)
FR (1) FR2194420B1 (xx)
GB (1) GB1406381A (xx)
HK (1) HK32477A (xx)
HU (1) HU167999B (xx)
IN (1) IN139119B (xx)
MY (1) MY7700267A (xx)
NL (1) NL170734C (xx)
PL (4) PL94195B1 (xx)
RO (2) RO68652A (xx)
SE (1) SE405856B (xx)
SU (3) SU691091A3 (xx)
YU (1) YU36957B (xx)
ZA (1) ZA735152B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4129737A (en) * 1972-08-02 1978-12-12 Laboratoire Roger Bellon Process for the preparation of an 8-alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)pyrimidine-6-carboxylic acid
JPS578110B2 (xx) * 1972-12-27 1982-02-15
JPS5059391A (xx) * 1973-09-28 1975-05-22
JPS5824438B2 (ja) * 1974-02-12 1983-05-20 大日本製薬株式会社 ２−（１− ピペラジニル ） ピリド （２，３−ｄ） ピリミジンユウドウタイノセイホウ
JPS5612636B2 (xx) * 1974-02-13 1981-03-23
GB1484138A (en) * 1974-03-14 1977-08-24 Bellon Labor Sa Roger Pyrido pyrimidine derivatives
JPS52151195A (en) * 1976-06-10 1977-12-15 Teijin Ltd Preparation of pyridopyrimidine carboxylic acid derivatives
JPS5312889A (en) * 1976-07-22 1978-02-04 Dainippon Pharmaceut Co Ltd P-aminobenzylpiperazine dervatives
JPS52106897A (en) * 1977-01-10 1977-09-07 Dainippon Pharmaceut Co Ltd Synthesis of piperazine derivatives
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten
DE2903850A1 (de) * 1979-02-01 1980-08-07 Bayer Ag 2-amino-8-cyclopropyl-5-oxo-5,8- dihydro-pyrido eckige klammer auf 2,3-d eckige klammer zu -pyrimidin-6-carnonsaeuren, verfahren zu ihrer herstellung sowie ihrer verwendung als antibakterielle mittel
US4215216A (en) * 1979-04-18 1980-07-29 American Home Products Corporation 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives
IT1209163B (it) * 1979-12-21 1989-07-10 Unibios S P A Trecate Novara Procedimento per la fabbricazione di: 6-alcossicarbonil-8-etil-5-oxo-5,8diidro-aperta par. quadrata 2,3-dchiusa par. quadrata-primidine 2-sostituite ed acidi libri corrispondenti.
JPS5693075A (en) * 1979-12-27 1981-07-28 Rhythm Watch Co Ltd Chiming mechanism for clock
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
US4774246A (en) * 1984-01-26 1988-09-27 Abbott Laboratories Quinoline antibacterial compounds
US4851535A (en) * 1985-01-23 1989-07-25 Toyama Chemical Co., Ltd. Nicotinic acid derivatives
JPS6229023A (ja) * 1985-07-30 1987-02-07 豊田合成株式会社 照明付きスイツチ用回路
US4689325A (en) * 1985-12-23 1987-08-25 Abbott Laboratories Isoxazolo-pyrido-phenoxazine and isothiazolo-pyrido-phenoxazine derivatives
US4687770A (en) * 1985-12-23 1987-08-18 Abbott Laboratories Isoxazolo-pyrido-benzoxazine and isothiazolo-pyrido-benzoxazine derivatives
JPS636489U (xx) * 1986-06-30 1988-01-16
US7133189B2 (en) 2002-02-22 2006-11-07 Tdk Corporation Magnetic garnet material, faraday rotator, optical device, bismuth-substituted rare earth-iron-garnet single-crystal film and method for producing the same and crucible for producing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641027A (en) * 1968-08-14 1972-02-08 American Home Prod 5 6 78-tetrahydro - 5 - oxo-pyrid o(23-d)-pyrimidine - 6 -carbonitriles and related compounds
JPS4837279B1 (xx) * 1970-08-29 1973-11-09
US3673184A (en) * 1970-09-02 1972-06-27 Dainippon Pharmaceutical Co Certain 2-substituted-5,8-dihydro-5-oxopyrido{8 2,3-d{9 pyrimidine-6-carboxylic acid derivatives

Also Published As

Publication number Publication date
CA1074793A (en) 1980-04-01
HU167999B (xx) 1976-02-28
JPS554755B2 (xx) 1980-01-31
DK152731B (da) 1988-05-02
FR2194420B1 (xx) 1975-10-17
NL7310731A (xx) 1974-02-05
DK152731C (da) 1988-10-24
JPS52106900A (en) 1977-09-07
DE2338325C2 (de) 1983-01-13
JPS5245719B2 (xx) 1977-11-17
JPS52111595A (en) 1977-09-19
JPS5516594B2 (xx) 1980-05-02
YU36957B (en) 1984-08-31
BE802860A (fr) 1973-11-16
FR2194420A1 (xx) 1974-03-01
PL94195B1 (xx) 1977-07-30
CS212738B2 (en) 1982-03-26
US3950338A (en) 1976-04-13
MY7700267A (en) 1977-12-31
DD107282A5 (xx) 1974-07-20
HK32477A (en) 1977-06-30
CH580100A5 (xx) 1976-09-30
GB1406381A (en) 1975-09-17
IN139119B (xx) 1976-05-08
ZA735152B (en) 1974-06-26
JPS5516593B2 (xx) 1980-05-02
SU691091A3 (ru) 1979-10-05
RO63452A (fr) 1978-07-15
JPS5434760B2 (xx) 1979-10-29
JPS4955694A (xx) 1974-05-30
SU544375A3 (ru) 1977-01-25
AU5880573A (en) 1975-02-06
JPS52106898A (en) 1977-09-07
NL170734C (nl) 1982-12-16
NL170734B (nl) 1982-07-16
DE2338325A1 (de) 1974-02-07
SU552032A3 (ru) 1977-03-25
JPS52106899A (en) 1977-09-07
YU208873A (en) 1982-02-25
PL94155B1 (xx) 1977-07-30
RO68652A (ro) 1980-01-15
PL94081B1 (xx) 1977-07-30
PL91614B1 (xx) 1977-03-31

Similar Documents

Publication Publication Date Title
SE405856B (sv) Forfarande for framstellning av 8-alkyl-5-oxo-2-piperazino-5,8-dihydro-pyrido(2,3-d)pyrimidin-6-karbonsyror
US4359578A (en) Naphthyridine derivatives and salts thereof useful as antibacterial agents
SU1588282A3 (ru) Способ получени производного хинолина, или его фармацевтически приемлемого сложного эфира, или фармацевтически приемлемых солей указанного производного или его эфира
Matsumoto et al. 1, 4-Dihydro-4-oxopyridinecarboxylic acids as antibacterial agents. 2. Synthesis and structure-activity relationships of 1, 6, 7-trisubstituted 1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acids, including enoxacin, a new antibacterial agent
KR910006806B1 (ko) 퀴놀린 유도체의 제조방법
FI77855B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 6-fluor-1,4-dihydro-4-oxo-3- kinolinkarboxylsyraderivat.
SU1075976A3 (ru) Способ получени производных 1,8-нафтиридина или их солей
CA1083149A (en) Derivatives of 10,11-dihydrobenzo 4,5 cyclohepta l,2- b -pyrazolo 4,3-e pyridine-5 (1h)ones
US4382937A (en) Naphthyridine derivatives and their use as anti-bacterials
US4051247A (en) Method of using 7-hydroxy-benzo[ij]quinolizine-2-carboxylic acid derivatives
AU1572188A (en) Process for the preparation of quinoline carboxylic acids
US4696928A (en) Substituted dihydroimidazo[1,2-a]quinoxalines
US3560483A (en) 1,4-dialkyl-3,6-diphenylepi(thio,dithia or tetrathia)-2,5-piperazinediones
US3673177A (en) Substituted 4-(anilinomethylene)-3-galanthamaninones
US4129737A (en) Process for the preparation of an 8-alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)pyrimidine-6-carboxylic acid
US4034094A (en) 8-Alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)pyrimidine-6-carboxylic acids for treating urinary tract infections
US4720495A (en) Benzo[ij]quinolizine-2-carboxylic acids useful for treating bacterial infection
US3313818A (en) 7, 10-dihydro-3, 10-dioxo-7-(lower-alkyl)-3h-pyrano[3, 2-f]quinoline-3-carboxylic acid derivatives
US3976651A (en) 7-Hydroxy-benzo[ij]quinolizine-2-carboxylic acids, intermediates, and a method for their production
CA1059509A (en) 8-alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d) pyrimidine-6-carboxylic acids and their preparation
US2657206A (en) 2, 4-diamino-5-aryloxy-pyrimidines
US4060527A (en) Pyrido[2,3-c]-acridine-1-hydroxy-2-carboxylic acid derivatives
SU1519529A3 (ru) Способ получени производного хинолина, его фармацевтически приемлемого сложного эфира или фармацевтически приемлемой соли производного хинолина или сложного эфира
US3985753A (en) 7-Hydroxy-benzo[ij]quinolizine-2-carboxylic acids and derivatives thereof
SU1558915A1 (ru) 2-(5 @ -Нитрофурил)-2,3-дигидро-5Н-1,3,4-тиадиазоло[2,3-в]-хиназолинон-5, про вл ющий противомикробную активность