SE388849B - Forfarande for framstellning av nya aminer med beta-receptorstimulerande verkan - Google Patents
Forfarande for framstellning av nya aminer med beta-receptorstimulerande verkanInfo
- Publication number
- SE388849B SE388849B SE7401958A SE7401958A SE388849B SE 388849 B SE388849 B SE 388849B SE 7401958 A SE7401958 A SE 7401958A SE 7401958 A SE7401958 A SE 7401958A SE 388849 B SE388849 B SE 388849B
- Authority
- SE
- Sweden
- Prior art keywords
- procedure
- preparation
- beta receptor
- receptor stimulating
- stimulating effects
- Prior art date
Links
- 150000001412 amines Chemical class 0.000 title 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 title 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 title 1
- 230000004936 stimulating effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (30)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7401958A SE388849B (sv) | 1974-02-14 | 1974-02-14 | Forfarande for framstellning av nya aminer med beta-receptorstimulerande verkan |
ZA00750381A ZA75381B (en) | 1974-02-14 | 1975-01-20 | Heart active compounds |
DE19752502993 DE2502993A1 (de) | 1974-02-14 | 1975-01-25 | Amine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
AT96475*#A AT334881B (de) | 1974-02-14 | 1975-02-10 | Verfahren zur herstellung neuer 1-phenoxy-2-hydroxy-3-aminopropane und deren saureadditionssalze |
DD184143A DD118614A5 (de) | 1974-02-14 | 1975-02-12 | |
CH169075A CH616648A5 (de) | 1974-02-14 | 1975-02-12 | |
FI750390A FI62055B (fi) | 1974-02-14 | 1975-02-12 | Foerfarande foer framstaellning av aminer som stimulerar hjaertats beta-receptorer |
SU752104405A SU603332A3 (ru) | 1974-02-14 | 1975-02-12 | Способ получени алканоламинов или их солей в виде рацемата или оптически-активных антиподов |
AU78116/75A AU497441B2 (en) | 1974-02-14 | 1975-02-12 | Heart active compounds |
US05/549,841 US4244969A (en) | 1974-02-14 | 1975-02-13 | Heart active compounds |
IE279/75A IE41350B1 (en) | 1974-02-14 | 1975-02-13 | Substituted phenoxypropanolamines |
NO750468A NO140628C (no) | 1974-02-14 | 1975-02-13 | Analogifremgangsmaate for fremstilling av nye, terapeutisk virksomme aminer |
HUHE678A HU169704B (de) | 1974-02-14 | 1975-02-13 | |
CA220,014A CA1052387A (en) | 1974-02-14 | 1975-02-13 | Heart active compounds |
FR7504553A FR2261000B1 (de) | 1974-02-14 | 1975-02-13 | |
GB6172/75A GB1492647A (en) | 1974-02-14 | 1975-02-13 | Substituted phenoxy propanolamines |
NL7501785A NL7501785A (nl) | 1974-02-14 | 1975-02-14 | Werkwijze ter bereiding van verbindingen die de werking van het hart beinvloeden, aldus bereide verbindingen en farmaceutische preparaten die deze verbindingen bevatten. |
JP50018088A JPS50116433A (de) | 1974-02-14 | 1975-02-14 | |
LU71846A LU71846A1 (de) | 1974-02-14 | 1975-02-14 | |
CS75986A CS202035B2 (en) | 1974-02-14 | 1975-02-14 | Process for preparing new p-hydroxyphenoxypropanolamines |
DK53975AA DK135711B (da) | 1974-02-14 | 1975-02-14 | Analogifremgangsmåde til fremstilling af hidtil ukendte, hjerteaktive substituerede fenoxyisopropanolaminer. |
BE153340A BE825515A (fr) | 1974-02-14 | 1975-02-14 | Composes agissant sur le coeur |
SU762315654A SU609460A3 (ru) | 1974-02-14 | 1976-01-20 | Способ получени производных аминопропанола или их солей |
SU7602314963A SU577971A3 (ru) | 1974-02-14 | 1976-01-23 | Способ получени производных пропаноламина или их солей |
AT414976A AT341497B (de) | 1974-02-14 | 1976-06-08 | Verfahren zur herstellung neuer 1-phenoxy-2-hydroxy-3-aminopropane und deren saureadditionssalze |
AT415076A AT341498B (de) | 1974-02-14 | 1976-06-08 | Verfahren zur herstellung neuer 1-phenoxy-2-hydroxy-3-aminopropane und deren saureadditionssalze |
CS785579A CS202036B2 (en) | 1974-02-14 | 1978-08-28 | Process for preparing new p-hydroxyphenoxypropanolamines |
CS785580A CS202037B2 (en) | 1974-02-14 | 1978-08-28 | Process for preparing new p-hydroxyphenoxypropanolamines |
IT7950875A IT7950875A0 (it) | 1974-02-14 | 1979-11-21 | Composti dotati di attivita' di stimolo dei beta-recettori cardiaci eprocedimento per la loro preparazione |
US06/150,883 US4336267A (en) | 1974-02-14 | 1980-05-19 | Heart active compounds and methods of use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7401958A SE388849B (sv) | 1974-02-14 | 1974-02-14 | Forfarande for framstellning av nya aminer med beta-receptorstimulerande verkan |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7401958L SE7401958L (de) | 1975-08-15 |
SE388849B true SE388849B (sv) | 1976-10-18 |
Family
ID=20320208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7401958A SE388849B (sv) | 1974-02-14 | 1974-02-14 | Forfarande for framstellning av nya aminer med beta-receptorstimulerande verkan |
Country Status (23)
Country | Link |
---|---|
US (2) | US4244969A (de) |
JP (1) | JPS50116433A (de) |
AT (1) | AT334881B (de) |
AU (1) | AU497441B2 (de) |
BE (1) | BE825515A (de) |
CA (1) | CA1052387A (de) |
CH (1) | CH616648A5 (de) |
CS (2) | CS202035B2 (de) |
DD (1) | DD118614A5 (de) |
DE (1) | DE2502993A1 (de) |
DK (1) | DK135711B (de) |
FI (1) | FI62055B (de) |
FR (1) | FR2261000B1 (de) |
GB (1) | GB1492647A (de) |
HU (1) | HU169704B (de) |
IE (1) | IE41350B1 (de) |
IT (1) | IT7950875A0 (de) |
LU (1) | LU71846A1 (de) |
NL (1) | NL7501785A (de) |
NO (1) | NO140628C (de) |
SE (1) | SE388849B (de) |
SU (3) | SU603332A3 (de) |
ZA (1) | ZA75381B (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5001161A (en) * | 1984-01-10 | 1991-03-19 | Aktiebolaget Hassle | Pharmaceutical composition comprising metroprolol succinate |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4210653A (en) * | 1978-06-27 | 1980-07-01 | Merck & Co., Inc. | Pyridyloxypropanolamines |
SE8004088L (sv) * | 1980-06-02 | 1981-12-03 | Haessle Ab | Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ... |
US4396629A (en) * | 1980-12-29 | 1983-08-02 | Sterling Drug Inc. | Compositions, processes and method |
CA1262729A (en) * | 1983-10-19 | 1989-11-07 | Leo Alig | Phenoxypropanolamines |
US5166218A (en) * | 1983-10-19 | 1992-11-24 | Hoffmann-La Roche Inc. | Phenoxypropanolamines and pharmaceutical compositions thereof |
DE3544172A1 (de) * | 1985-12-13 | 1987-06-19 | Lentia Gmbh | Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung |
ATE67480T1 (de) * | 1987-03-26 | 1991-10-15 | Helopharm Petrik Co Kg | Verfahren zur herstellung von 5-hydroxydiprafenon und seiner salze mit saeuren. |
IL126458A (en) * | 1996-04-09 | 2004-06-20 | Nps Pharma Inc | Calcium receptor inhibiting calcilytic compounds |
US6818660B2 (en) | 1996-04-09 | 2004-11-16 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
US5966498A (en) * | 1996-08-07 | 1999-10-12 | Lakewood Engineering And Manufacturing Company | End closure assembly for oil-filled heater |
TW483881B (en) | 1996-12-03 | 2002-04-21 | Nps Pharma Inc | Calcilytic compounds |
US7202261B2 (en) | 1996-12-03 | 2007-04-10 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
JP4604583B2 (ja) * | 2004-07-20 | 2011-01-05 | ダイソー株式会社 | 1−アミド−3−(2−ヒドロキシフェノキシ)−2−プロパノール誘導体、ならびに2−アミドメチル−1,4−ベンゾジオキサン誘導体の製造法 |
IL165365A0 (en) | 2004-11-24 | 2006-01-15 | Q Core Ltd | Finger-type peristaltic pump |
JP4934287B2 (ja) * | 2005-04-05 | 2012-05-16 | 花王株式会社 | 美白剤 |
FR2916441B1 (fr) * | 2007-05-22 | 2009-08-28 | Clariant Specialty Fine Chem | Procede de racemisation d'alpha-aminoacetals optiquement actifs. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL301580A (de) * | 1962-12-11 | |||
GB1069345A (en) * | 1963-07-19 | 1967-05-17 | Ici Ltd | New alkanolamine derivatives |
DE1922003C3 (de) * | 1969-04-30 | 1979-10-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz |
BE790165A (fr) * | 1971-12-14 | 1973-02-15 | Parke Davis & Co | Nouveaux aminoalcanols et procede pour les preparer |
-
1974
- 1974-02-14 SE SE7401958A patent/SE388849B/xx unknown
-
1975
- 1975-01-20 ZA ZA00750381A patent/ZA75381B/xx unknown
- 1975-01-25 DE DE19752502993 patent/DE2502993A1/de not_active Ceased
- 1975-02-10 AT AT96475*#A patent/AT334881B/de not_active IP Right Cessation
- 1975-02-12 CH CH169075A patent/CH616648A5/de not_active IP Right Cessation
- 1975-02-12 AU AU78116/75A patent/AU497441B2/en not_active Expired
- 1975-02-12 SU SU752104405A patent/SU603332A3/ru active
- 1975-02-12 DD DD184143A patent/DD118614A5/xx unknown
- 1975-02-12 FI FI750390A patent/FI62055B/fi not_active Application Discontinuation
- 1975-02-13 US US05/549,841 patent/US4244969A/en not_active Expired - Lifetime
- 1975-02-13 FR FR7504553A patent/FR2261000B1/fr not_active Expired
- 1975-02-13 CA CA220,014A patent/CA1052387A/en not_active Expired
- 1975-02-13 IE IE279/75A patent/IE41350B1/xx unknown
- 1975-02-13 NO NO750468A patent/NO140628C/no unknown
- 1975-02-13 HU HUHE678A patent/HU169704B/hu unknown
- 1975-02-13 GB GB6172/75A patent/GB1492647A/en not_active Expired
- 1975-02-14 DK DK53975AA patent/DK135711B/da unknown
- 1975-02-14 JP JP50018088A patent/JPS50116433A/ja active Pending
- 1975-02-14 BE BE153340A patent/BE825515A/xx unknown
- 1975-02-14 NL NL7501785A patent/NL7501785A/xx not_active Application Discontinuation
- 1975-02-14 LU LU71846A patent/LU71846A1/xx unknown
- 1975-02-14 CS CS75986A patent/CS202035B2/cs unknown
-
1976
- 1976-01-20 SU SU762315654A patent/SU609460A3/ru active
- 1976-01-23 SU SU7602314963A patent/SU577971A3/ru active
-
1978
- 1978-08-28 CS CS785579A patent/CS202036B2/cs unknown
-
1979
- 1979-11-21 IT IT7950875A patent/IT7950875A0/it unknown
-
1980
- 1980-05-19 US US06/150,883 patent/US4336267A/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5001161A (en) * | 1984-01-10 | 1991-03-19 | Aktiebolaget Hassle | Pharmaceutical composition comprising metroprolol succinate |
Also Published As
Publication number | Publication date |
---|---|
FI750390A (de) | 1975-08-15 |
AU497441B2 (en) | 1978-12-14 |
SU577971A3 (ru) | 1977-10-25 |
BE825515A (fr) | 1975-08-14 |
GB1492647A (en) | 1977-11-23 |
NO140628B (no) | 1979-07-02 |
DD118614A5 (de) | 1976-03-12 |
HU169704B (de) | 1977-02-28 |
FR2261000A1 (de) | 1975-09-12 |
DK53975A (de) | 1975-10-06 |
US4336267A (en) | 1982-06-22 |
ATA96475A (de) | 1976-06-15 |
DE2502993A1 (de) | 1975-09-04 |
IE41350L (en) | 1975-08-14 |
AU7811675A (en) | 1976-08-12 |
NL7501785A (nl) | 1975-08-18 |
CA1052387A (en) | 1979-04-10 |
IT7950875A0 (it) | 1979-11-21 |
LU71846A1 (de) | 1975-12-09 |
FR2261000B1 (de) | 1978-07-21 |
SU603332A3 (ru) | 1978-04-15 |
SE7401958L (de) | 1975-08-15 |
CS202035B2 (en) | 1980-12-31 |
US4244969A (en) | 1981-01-13 |
IE41350B1 (en) | 1979-12-19 |
JPS50116433A (de) | 1975-09-11 |
CS202036B2 (en) | 1980-12-31 |
NO750468L (de) | 1975-08-15 |
ZA75381B (en) | 1976-01-28 |
DK135711B (da) | 1977-06-13 |
SU609460A3 (ru) | 1978-05-30 |
NO140628C (no) | 1979-10-10 |
FI62055B (fi) | 1982-07-30 |
DK135711C (de) | 1977-11-21 |
CH616648A5 (de) | 1980-04-15 |
AT334881B (de) | 1977-02-10 |
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