SE406763B - Forfarande for framstellning av nya imidazoliner med antihypertensiv verkan - Google Patents

Forfarande for framstellning av nya imidazoliner med antihypertensiv verkan

Info

Publication number
SE406763B
SE406763B SE7210578A SE1057872A SE406763B SE 406763 B SE406763 B SE 406763B SE 7210578 A SE7210578 A SE 7210578A SE 1057872 A SE1057872 A SE 1057872A SE 406763 B SE406763 B SE 406763B
Authority
SE
Sweden
Prior art keywords
procedure
preparation
hypertensive effect
imidazolines
new
Prior art date
Application number
SE7210578A
Other languages
English (en)
Inventor
W L Matier
W T Comer
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE406763B publication Critical patent/SE406763B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/46—Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/52—Nitrogen atoms not forming part of a nitro radical with hetero atoms directly attached to said nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7210578A 1971-08-16 1972-08-15 Forfarande for framstellning av nya imidazoliner med antihypertensiv verkan SE406763B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17232171A 1971-08-16 1971-08-16
US00268380A US3821244A (en) 1971-08-16 1972-07-03 2-amino-4-phenyl-2-imidazolines

Publications (1)

Publication Number Publication Date
SE406763B true SE406763B (sv) 1979-02-26

Family

ID=26867960

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7210578A SE406763B (sv) 1971-08-16 1972-08-15 Forfarande for framstellning av nya imidazoliner med antihypertensiv verkan

Country Status (16)

Country Link
US (1) US3821244A (sv)
JP (1) JPS5719106B2 (sv)
BE (1) BE787617A (sv)
CA (1) CA1018174A (sv)
CH (2) CH579055A5 (sv)
DE (1) DE2240256A1 (sv)
DK (1) DK139098B (sv)
FR (1) FR2150766B1 (sv)
GB (1) GB1347930A (sv)
HU (1) HU165660B (sv)
IE (1) IE36865B1 (sv)
IL (1) IL40123A (sv)
NL (1) NL7211173A (sv)
PH (2) PH11940A (sv)
SE (1) SE406763B (sv)
YU (1) YU35355B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914249A (en) * 1973-10-30 1975-10-21 Mead Johnson & Co 4-(3,4-Dichlorophenyl)-2-(methylamino)-2-imadazoline
US3953348A (en) * 1973-12-13 1976-04-27 Standard Oil Company Oil-soluble reaction products of intermediate (a) from a high molecular weight olefin polymer, acetonitrile, and chlorine with (b) a piperazine, and lubricant compositions containing the same
HU179019B (en) * 1978-11-01 1982-08-28 Gyogyszekutato Intezet Process for preparing 4-//3,4-dialkoxy-phenyl/-alkyl/- 2imidazolidinone derivatives
JPS5877051U (ja) * 1981-11-16 1983-05-24 富士通株式会社 Ｉｃアダプタ
DE3674054D1 (de) * 1985-04-26 1990-10-18 Hoffmann La Roche 1,3-disubstituierte imidazoliumsalze.
AU6831996A (en) * 1995-09-07 1997-03-27 Novartis Ag Substituted phosphinic compounds and their use as pharmaceuticals
HUP0400405A3 (en) * 2004-02-10 2009-03-30 Sanofi Synthelabo Pyrimidine derivatives, process for producing them, their use, pharmaceutical compositions containing them and their intermediates

Also Published As

Publication number Publication date
NL7211173A (sv) 1973-02-20
DE2240256A1 (de) 1973-02-22
CA1018174A (en) 1977-09-27
JPS5719106B2 (sv) 1982-04-20
FR2150766B1 (sv) 1976-05-21
IL40123A (en) 1975-05-22
YU35355B (en) 1980-12-31
CH579055A5 (sv) 1976-08-31
PH11940A (en) 1978-09-15
CH591451A5 (sv) 1977-09-15
DK139098B (da) 1978-12-18
GB1347930A (en) 1974-02-27
IE36865B1 (en) 1977-03-16
DK139098C (sv) 1979-05-28
IE36865L (en) 1973-02-16
JPS4829770A (sv) 1973-04-19
US3821244A (en) 1974-06-28
HU165660B (sv) 1974-10-28
FR2150766A1 (sv) 1973-04-13
YU207472A (en) 1980-06-30
IL40123A0 (en) 1972-10-29
PH11915A (en) 1978-09-08
BE787617A (fr) 1973-02-16

Similar Documents

Publication Publication Date Title
FI56686B (fi) Foerfarande foer framstaellning av 7-aminocefalosporansyraderivat med antibiotis verkan
SE417205B (sv) Forfarande for framstellning av foreningar med autibiotisk verkan
FI56839B (fi) Foerfarande foer framstaellning av nya antibakteriella penicillinderivat
SE389670B (sv) Forfarande for framstellning av aroyl-substituerade pyrroler med terapeutisk verkan
SE405599B (sv) Forfarande for framstellning av pyridazinoner med terapeutisk verkan
SE380529B (sv) Analogiforfaranden for framstellning av nya azepinderivat
SE380522B (sv) Forfarande for framstellning av (1- (p-klorbensoyl)-5-metoxi-2-metyl-3-indol) - acetoxiettiksyra med antiflogistisk verkan
SE405477B (sv) Forfarande for framstellning av tetrazolyl-kinaldinsyraderivat med farmakologisk verkan
SE397680B (sv) Forfarande for framstellning av nya heterocykliska estrar av bensopyranopyridiner
SE405851B (sv) Forfarande for framstellning av nya 2-aminometylenindanoner med analgetisk verkan
SE395892B (sv) Forfarande for framstellning av piperidyl-bensimidazoliner med terapeutisk verkan
SE401673B (sv) Forfarande for framstellning av 2-substituerade 5-sulfamyl-bensoesyror med plasmalipidsenkande verkan
SE406763B (sv) Forfarande for framstellning av nya imidazoliner med antihypertensiv verkan
SE386902B (sv) Forfarande for framstellning av nya cefalosporiner
FI55499B (fi) Foerfarande foer framstaellning av nya n-substituerade imidazoler med antimykotisk verkan
SE382980B (sv) Forfarande for framstellning av nya derivat av hexahydrofenantridin
SE386681B (sv) Forfarande for framstellning av nya cefalosporinderivat
SE387936B (sv) Forfarande for framstellning av substituerade metoxiaminer
SE384210B (sv) Forfarande for framstellning av nya nitrosokarbamidderivat
SE409866B (sv) Forfarande for framstellning av adenosinderivat
SE417206B (sv) Forfarande for framstellning av foreningar med autibiotisk verkan
SE394680B (sv) Forfarande for framstellning av cykliska fosfamidderivat
SE389108B (sv) Forfarande for framstellning av cyklopropylfenylpyrrolidinderivat med farmakologisk verkan
SE395689B (sv) Forfarande for framstellning av vissa angivna bensalacetonamidinohydrazonderivat med antiviral verkan
SE390733B (sv) Forfarande for framstellning av nya substituerade n-hydroxialkyl-2-fenylamino-imidazoliner-(2) med blocktryckssenkande effekt