SE0301569D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0301569D0
SE0301569D0 SE0301569A SE0301569A SE0301569D0 SE 0301569 D0 SE0301569 D0 SE 0301569D0 SE 0301569 A SE0301569 A SE 0301569A SE 0301569 A SE0301569 A SE 0301569A SE 0301569 D0 SE0301569 D0 SE 0301569D0
Authority
SE
Sweden
Prior art keywords
novel compounds
novel
compounds
Prior art date
Application number
SE0301569A
Other languages
English (en)
Swedish (sv)
Inventor
Roger Bonnert
Rukhsana Rasul
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0301569A priority Critical patent/SE0301569D0/xx
Publication of SE0301569D0 publication Critical patent/SE0301569D0/xx
Priority to SE0302305A priority patent/SE0302305D0/xx
Priority to TW099109193A priority patent/TW201024261A/zh
Priority to TW093114113A priority patent/TWI328004B/zh
Priority to ARP040101792A priority patent/AR044552A1/es
Priority to PT10180348T priority patent/PT2281815E/pt
Priority to NZ543722A priority patent/NZ543722A/xx
Priority to MXPA05012680A priority patent/MXPA05012680A/es
Priority to AU2004242624A priority patent/AU2004242624B2/en
Priority to EP04734774A priority patent/EP1656346B1/en
Priority to ES04734774T priority patent/ES2322650T3/es
Priority to BRPI0410711A priority patent/BRPI0410711B8/pt
Priority to SI200431669T priority patent/SI2025670T1/sl
Priority to ES08165755T priority patent/ES2361485T3/es
Priority to PL08165755T priority patent/PL2025670T3/pl
Priority to UAA200511010A priority patent/UA84701C2/ru
Priority to EP08165755A priority patent/EP2025670B1/en
Priority to CN2011102633202A priority patent/CN102391171A/zh
Priority to HR20090281T priority patent/HRP20090281T1/xx
Priority to PCT/SE2004/000808 priority patent/WO2004106302A1/en
Priority to PT08165755T priority patent/PT2025670E/pt
Priority to DE602004020072T priority patent/DE602004020072D1/de
Priority to PT04734774T priority patent/PT1656346E/pt
Priority to PL04734774T priority patent/PL1656346T3/pl
Priority to US10/558,228 priority patent/US7687535B2/en
Priority to KR1020117009790A priority patent/KR20110050754A/ko
Priority to KR1020117009788A priority patent/KR101067535B1/ko
Priority to AT08165755T priority patent/ATE502010T1/de
Priority to SI200431874T priority patent/SI2281815T1/sl
Priority to MYPI20041992A priority patent/MY144483A/en
Priority to DK10180348.4T priority patent/DK2281815T3/da
Priority to RU2005137403/04A priority patent/RU2361860C2/ru
Priority to DK08165755.3T priority patent/DK2025670T3/da
Priority to CN2004800146027A priority patent/CN1795174B/zh
Priority to SI200431120T priority patent/SI1656346T1/sl
Priority to PL10180348T priority patent/PL2281815T3/pl
Priority to KR1020057022513A priority patent/KR101067586B1/ko
Priority to JP2006532212A priority patent/JP4541361B2/ja
Priority to DK04734774T priority patent/DK1656346T3/da
Priority to HK06111158.9A priority patent/HK1090635B/xx
Priority to AT04734774T priority patent/ATE425965T1/de
Priority to CA2526866A priority patent/CA2526866C/en
Priority to EP10180348A priority patent/EP2281815B1/en
Priority to DE602004031894T priority patent/DE602004031894D1/de
Priority to ES10180348T priority patent/ES2382606T3/es
Priority to AT10180348T priority patent/ATE552243T1/de
Priority to IL171928A priority patent/IL171928A/en
Priority to CO05118882A priority patent/CO5630030A2/es
Priority to ZA200509598A priority patent/ZA200509598B/en
Priority to IS8189A priority patent/IS2722B/is
Priority to NO20056130A priority patent/NO20056130L/no
Priority to IL194872A priority patent/IL194872A0/en
Priority to US12/397,618 priority patent/US20090163518A1/en
Priority to CY20091100564T priority patent/CY1109104T1/el
Priority to HK11107570.0A priority patent/HK1149563B/en
Priority to HK09105852.7A priority patent/HK1126773B/en
Priority to JP2010082748A priority patent/JP2010155862A/ja
Priority to IS8920A priority patent/IS8920A/is
Priority to US13/047,280 priority patent/US20110263614A1/en
Priority to IL212265A priority patent/IL212265A0/en
Priority to IL212371A priority patent/IL212371A0/en
Priority to HR20110359T priority patent/HRP20110359T1/hr
Priority to CY20111100464T priority patent/CY1111469T1/el
Priority to US13/344,051 priority patent/US20120178764A1/en
Priority to HRP20120390TT priority patent/HRP20120390T1/hr
Priority to CY20121100486T priority patent/CY1112853T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE0301569A 2003-05-27 2003-05-27 Novel compounds SE0301569D0 (sv)

Priority Applications (66)

Application Number Priority Date Filing Date Title
SE0301569A SE0301569D0 (sv) 2003-05-27 2003-05-27 Novel compounds
SE0302305A SE0302305D0 (sv) 2003-05-27 2003-08-27 Novel Compounds
TW099109193A TW201024261A (en) 2003-05-27 2004-05-19 Substituted indoles and preparation and use thereof
TW093114113A TWI328004B (en) 2003-05-27 2004-05-19 Substituted indoles and use thereof
ARP040101792A AR044552A1 (es) 2003-05-27 2004-05-24 Derivados del indol,composiciones farmaceuticas que los contienen y procesos para su preparacion, de utilidad para el tratamiento de trastornos respiratorios
PT10180348T PT2281815E (pt) 2003-05-27 2004-05-25 Composto intermediário de éster etílico do ácido 4-(acetilamino)-3-[(4-clorofenil)tio]-2-metil-1h-indole- 1-acético
NZ543722A NZ543722A (en) 2003-05-27 2004-05-25 Novel substituted 3-sulfur indoles
MXPA05012680A MXPA05012680A (es) 2003-05-27 2004-05-25 Indoles novedosos de 3-azufre sustituidos.
AU2004242624A AU2004242624B2 (en) 2003-05-27 2004-05-25 Novel substituted 3-sulfur indoles
EP04734774A EP1656346B1 (en) 2003-05-27 2004-05-25 1,2,3,4-tetrasubstituted indole for the treatment of respiratory diseases
ES04734774T ES2322650T3 (es) 2003-05-27 2004-05-25 Indol 1,2,3,4-tetrasustituido para el tratamiento de enfermedades respiratorias.
BRPI0410711A BRPI0410711B8 (pt) 2003-05-27 2004-05-25 ácido 4-(acetilamina)-3-[(4-clorofenil)tio]-2-metil-1h-indol-1-acético
SI200431669T SI2025670T1 (sl) 2003-05-27 2004-05-25 Uporaba derivatov 3-feniltio-1H-indol-1-ocetne kisline kot modulatorjev aktivnosti CRTh2 receptorja
ES08165755T ES2361485T3 (es) 2003-05-27 2004-05-25 Uso de derivados de ácido 3-feniltio-1h-indol-acético como moduladores de la actividad del receptor crth2.
PL08165755T PL2025670T3 (pl) 2003-05-27 2004-05-25 Zastosowanie pochodnych kwasu 3-fenylotio-1H-indolo-1-octowego jako modulatorów aktywności receptora CRTh2
UAA200511010A UA84701C2 (ru) 2003-05-27 2004-05-25 Замещенные индолы, способ их получения, их использования
EP08165755A EP2025670B1 (en) 2003-05-27 2004-05-25 Use of 3-phenylthio-1H-indole-1-acetic acid derivatives as modulators of CRTh2 receptor activity
CN2011102633202A CN102391171A (zh) 2003-05-27 2004-05-25 新型取代的3-硫吲哚
HR20090281T HRP20090281T1 (hr) 2003-05-27 2004-05-25 1,2,3,4-tetrasubstituirani indol za liječenje respiratornih bolesti
PCT/SE2004/000808 WO2004106302A1 (en) 2003-05-27 2004-05-25 Novel substituted 3-sulfur indoles
PT08165755T PT2025670E (pt) 2003-05-27 2004-05-25 Utiliza??o de derivados do ?cido 3-feniltio-1h-indole-1-ac?tico como moduladores da actividade dos receptores crth2
DE602004020072T DE602004020072D1 (de) 2003-05-27 2004-05-25 1,2,3,4-tetrasubstituiertes indol zur behandlung von atemwegserkrankungen
PT04734774T PT1656346E (pt) 2003-05-27 2004-05-25 Indole 1,2,3,4-tetrassubstituído para o tratamento de doenças respiratórias
PL04734774T PL1656346T3 (pl) 2003-05-27 2004-05-25 1,2,3,4-Tetrapodstawiony indol do leczenia chorób dróg oddechowych
US10/558,228 US7687535B2 (en) 2003-05-27 2004-05-25 Substituted 3-sulfur indoles
KR1020117009790A KR20110050754A (ko) 2003-05-27 2004-05-25 신규한 치환된 3-황 인돌
KR1020117009788A KR101067535B1 (ko) 2003-05-27 2004-05-25 신규한 치환된 3-황 인돌
AT08165755T ATE502010T1 (de) 2003-05-27 2004-05-25 Verwendung von 3-phenylthio-1h-indol-1-essigsäure-derivate als modulatoren der crth2-rezeptor- aktivität
SI200431874T SI2281815T1 (sl) 2003-05-27 2004-05-25 Vmesna spojina etil estra 4-(acetilamino)-3-((4-klorofenil)tio)-2-metil-1H-indol-1-ocetne kisline
MYPI20041992A MY144483A (en) 2003-05-27 2004-05-25 1,2,3,4-tetrasubstituted indole for the treatment of respiratory diseases
DK10180348.4T DK2281815T3 (da) 2003-05-27 2004-05-25 4-(Acetylamino)-3-[(4-chlorophenyl)thio]-2-methyl-1H-indole-1-acetic acid ethyl ester intermediate compound
RU2005137403/04A RU2361860C2 (ru) 2003-05-27 2004-05-25 Новые замещенные 3-сера-индолы
DK08165755.3T DK2025670T3 (da) 2003-05-27 2004-05-25 Anvendelse af 3-phenylthio-1H-indol-1-eddikesyre-derivater som modulatorer af CRTh2-receptor aktivitet
CN2004800146027A CN1795174B (zh) 2003-05-27 2004-05-25 取代的3-硫吲哚
SI200431120T SI1656346T1 (sl) 2003-05-27 2004-05-25 1,2,3,4-tetrasubstituiran indol za zdravljenje respiratornih bolezni
PL10180348T PL2281815T3 (pl) 2003-05-27 2004-05-25 Związek pośredni, ester etylowy kwasu 4-(acetyloamino)-3-[(4-chlorofenylo}tio]-2-metylo-1H-indolooctowego
KR1020057022513A KR101067586B1 (ko) 2003-05-27 2004-05-25 신규한 치환된 3-황 인돌
JP2006532212A JP4541361B2 (ja) 2003-05-27 2004-05-25 新規３位硫黄置換インドール
DK04734774T DK1656346T3 (da) 2003-05-27 2004-05-25 1,2,3,4-tetrasubstituerede indol til behandling af luftvejssygdomme
HK06111158.9A HK1090635B (en) 2003-05-27 2004-05-25 Substituted 3-sulfur indoles
AT04734774T ATE425965T1 (de) 2003-05-27 2004-05-25 1,2,3,4-tetrasubstituiertes indol zur behandlung von atemwegserkrankungen
CA2526866A CA2526866C (en) 2003-05-27 2004-05-25 Substituted 3-sulfur indoles for treating a disease mediated by crth2
EP10180348A EP2281815B1 (en) 2003-05-27 2004-05-25 4-(Acetylamino)-3-[(4-chlorophenyl)thio]-2-methyl-1H-indole-1-acetic acid ethyl ester intermediate compound
DE602004031894T DE602004031894D1 (de) 2003-05-27 2004-05-25 Verwendung von 3-Phenylthio-1H-indol-1-essigsäure-Derivate als Modulatoren der CRTh2-Rezeptor-Aktivität
ES10180348T ES2382606T3 (es) 2003-05-27 2004-05-25 Compuesto intermedio éster etílico del ácido 4-(acetilamino)-3-[(4-clorofenil)tio]-2-metil-1H-indol-acético
AT10180348T ATE552243T1 (de) 2003-05-27 2004-05-25 4-(acetylamino)-3-ä(4-chlorophenyl)thioü-2-meth l-1h-indole-1-essigsäure-ethyl-ester zwischenverbindung
IL171928A IL171928A (en) 2003-05-27 2005-11-14 Compounds of 4 - (acetylamino) - 3 - [(4 - chlorophenyl) thio] - 2 - methyl - 1H - indole - 1 - acetic acid, salts and their solvates, and their uses in the preparation of medicine
CO05118882A CO5630030A2 (es) 2003-05-27 2005-11-23 Acido 4-(acetilamino)-3-{(4-clorofenil)tio}-2-metil-1h-indol-1-acetico y composicion farmaceutica que lo contiene
ZA200509598A ZA200509598B (en) 2003-05-27 2005-11-28 Novel substituted 3-sulfur indoles
IS8189A IS2722B (is) 2003-05-27 2005-12-20 1, 2, 3, 4- Tetrasetin indól til meðhöndlunar á öndunarfærasjúkdómum
NO20056130A NO20056130L (no) 2003-05-27 2005-12-22 Nye substituerte 3-svovelindoler
IL194872A IL194872A0 (en) 2003-05-27 2008-10-23 Novel substituted 3-sulfur indoles
US12/397,618 US20090163518A1 (en) 2003-05-27 2009-03-04 Novel Compounds
CY20091100564T CY1109104T1 (el) 2003-05-27 2009-05-28 1,2,3,4 τετρα-υποκατεστημενη ινδολη για την αντιμετωπιση ασθενειων του αναπνευστικου
HK11107570.0A HK1149563B (en) 2003-05-27 2009-06-30 4-(acetylamino)-3-[(4-chlorophenyl)thio]-2-methyl-1h-indole-1-acetic acid ethyl ester intermediate compound
HK09105852.7A HK1126773B (en) 2003-05-27 2009-06-30 Use of 3-phenylthio-1h-indole-1-acetic acid derivatives as modulators of crth2 receptor activity
JP2010082748A JP2010155862A (ja) 2003-05-27 2010-03-31 新規３位硫黄置換インドール
IS8920A IS8920A (is) 2003-05-27 2010-08-09 3-(Fenýl eða kínólyl)þíó- 1H-idnól-1-ediksýru afleður sem mótarar á virkni CRTh2 vitaka.
US13/047,280 US20110263614A1 (en) 2003-05-27 2011-03-14 Novel compounds
IL212265A IL212265A0 (en) 2003-05-27 2011-04-11 Novel compounds
IL212371A IL212371A0 (en) 2003-05-27 2011-04-14 Novel compounds
HR20110359T HRP20110359T1 (hr) 2003-05-27 2011-05-16 Upotreba derivata 3-feniltio-1h-indol-1-octene kiseline kao modulatora crth2 receptorske aktivnosti
CY20111100464T CY1111469T1 (el) 2003-05-27 2011-05-16 ΧΡΗΣΗ ΠΑΡΑΓΩΓΩΝ 3-ΦΑΙΝΥΛΘΕΙΟ-1Η-ΙΝΔΟΛΗ-1-ΟΞΙΚΟΥ ΟΞΕΟΣ ΩΣ ΡΥΘΜΙΣΤΕΣ ΤΗΣ ΔΡΑΣΗΣ ΤΟΥ ΥΠΟΔΟΧΕΑ CRTh2
US13/344,051 US20120178764A1 (en) 2003-05-27 2012-01-05 Novel Compounds
HRP20120390TT HRP20120390T1 (hr) 2003-05-27 2012-05-10 Intermedijarni spoj etil estera 4-(acetilamino)-3-[(4-klorofenil)tio]-2-metil-1h-indol-1-octene kiseline
CY20121100486T CY1112853T1 (el) 2003-05-27 2012-05-29 Ενδιαμεση ενωση 4-(ακετυλαμινο)-3-[(4-χλωροφαινυλ)θειο]-2-μεθυλ-1η-ινδολη-1-οξικο οξυ αιθυλεστερα

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