SE0300119D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0300119D0
SE0300119D0 SE0300119A SE0300119A SE0300119D0 SE 0300119 D0 SE0300119 D0 SE 0300119D0 SE 0300119 A SE0300119 A SE 0300119A SE 0300119 A SE0300119 A SE 0300119A SE 0300119 D0 SE0300119 D0 SE 0300119D0
Authority
SE
Sweden
Prior art keywords
sup
novel compounds
compounds
formula
relates
Prior art date
Application number
SE0300119A
Other languages
English (en)
Swedish (sv)
Inventor
Simon Guile
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0300119A priority Critical patent/SE0300119D0/xx
Publication of SE0300119D0 publication Critical patent/SE0300119D0/xx
Priority to EP04702477A priority patent/EP1587812B1/en
Priority to PCT/SE2004/000052 priority patent/WO2004065394A1/en
Priority to BRPI0406801A priority patent/BRPI0406801B8/pt
Priority to PL378222A priority patent/PL214682B1/pl
Priority to MXPA05007496A priority patent/MXPA05007496A/es
Priority to JP2006500750A priority patent/JP4519121B2/ja
Priority to DE602004001857T priority patent/DE602004001857T2/de
Priority to RU2005121494/04A priority patent/RU2331647C2/ru
Priority to HK06102161.3A priority patent/HK1081959B/en
Priority to NZ541217A priority patent/NZ541217A/en
Priority to ES04702477T priority patent/ES2270337T3/es
Priority to KR1020117022785A priority patent/KR20110125256A/ko
Priority to AU2004206012A priority patent/AU2004206012B2/en
Priority to KR1020057013126A priority patent/KR101107486B1/ko
Priority to CA2512441A priority patent/CA2512441C/en
Priority to AT04702477T priority patent/ATE335748T1/de
Priority to US10/542,197 priority patent/US7384951B2/en
Priority to UAA200506377A priority patent/UA81788C2/uk
Priority to CNB2004800071073A priority patent/CN100334093C/zh
Priority to IL169370A priority patent/IL169370A/en
Priority to ZA2005/05364A priority patent/ZA200505364B/en
Priority to EGNA2005000380 priority patent/EG25613A/xx
Priority to IS7965A priority patent/IS2376B/is
Priority to NO20053826A priority patent/NO333702B1/no
Priority to US12/115,171 priority patent/US20080214579A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE0300119A 2003-01-17 2003-01-17 Novel compounds SE0300119D0 (sv)

Priority Applications (26)

Application Number Priority Date Filing Date Title
SE0300119A SE0300119D0 (sv) 2003-01-17 2003-01-17 Novel compounds
CNB2004800071073A CN100334093C (zh) 2003-01-17 2004-01-15 噻吩并嘧啶二酮及其在调节自身免疫疾病中的用途
KR1020117022785A KR20110125256A (ko) 2003-01-17 2004-01-15 티에노피리미딘디온 및 그들의 자가면역 질환 조절 용도
KR1020057013126A KR101107486B1 (ko) 2003-01-17 2004-01-15 티에노피리미딘디온 및 그들의 자가면역 질환 조절 용도
BRPI0406801A BRPI0406801B8 (pt) 2003-01-17 2004-01-15 derivados de tieno-pirimidinodiona e uso dos mesmos na modulação de doenças autoimunes
PL378222A PL214682B1 (pl) 2003-01-17 2004-01-15 Tienopirymidynodiony, sposób ich wytwarzania oraz zawierajacy je srodek farmaceutyczny
MXPA05007496A MXPA05007496A (es) 2003-01-17 2004-01-15 Tienopirimidindionas y su uso en la modulacion de enfermedades autoinmunes.
JP2006500750A JP4519121B2 (ja) 2003-01-17 2004-01-15 自己免疫疾患の調節におけるチエノピリミジンジオンとその使用
DE602004001857T DE602004001857T2 (de) 2003-01-17 2004-01-15 Thienopyrimidindione und deren verwendung bei der modulierung von autoimmunerkrankungen
RU2005121494/04A RU2331647C2 (ru) 2003-01-17 2004-01-15 Тиенопиримидиндионы и их применение в модулировании аутоиммунного заболевания
HK06102161.3A HK1081959B (en) 2003-01-17 2004-01-15 Thienopyrimidinediones and their use in the modulation of autoimmune disease
NZ541217A NZ541217A (en) 2003-01-17 2004-01-15 Thienopyrimidinediones and their use in the modulation of autoimmune disease
ES04702477T ES2270337T3 (es) 2003-01-17 2004-01-15 Tienopirimidindionas y su uso en la modulacion de la enfermedad autoinmunitaria.
EP04702477A EP1587812B1 (en) 2003-01-17 2004-01-15 Thienopyrimidinediones and their use in the modulation of autoimmune disease
AU2004206012A AU2004206012B2 (en) 2003-01-17 2004-01-15 Thienopyrimidinediones and their use in the modulation of autoimmune disease
PCT/SE2004/000052 WO2004065394A1 (en) 2003-01-17 2004-01-15 Thienopyrimidinediones and their use in the modulation of autoimmune disease
CA2512441A CA2512441C (en) 2003-01-17 2004-01-15 Thienopyrimidinediones and their use in the modulation of autoimmune disease
AT04702477T ATE335748T1 (de) 2003-01-17 2004-01-15 Thienopyrimidindione und deren verwendung bei der modulierung von autoimmunerkrankungen
US10/542,197 US7384951B2 (en) 2003-01-17 2004-01-15 Thienopyrimidinediones and their use in the modulation of autoimmune disease
UAA200506377A UA81788C2 (uk) 2003-01-17 2004-01-15 Тієнопіримідиндіони і їх використання у модуляції аутоімунних хвороб
IL169370A IL169370A (en) 2003-01-17 2005-06-23 Thienopyrimidinediones and their use in the modulation of autoimmune disease
ZA2005/05364A ZA200505364B (en) 2003-01-17 2005-07-01 Thienopyrimidinediones and their use in the modulation of autoimmune disease
EGNA2005000380 EG25613A (en) 2003-01-17 2005-07-12 Thienopyrimidinediones and their use in the modulation of autoimmune disease
IS7965A IS2376B (is) 2003-01-17 2005-07-29 Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi
NO20053826A NO333702B1 (no) 2003-01-17 2005-08-15 Tienopyrimidindioner, fremgangsmater for deres fremstilling, farmasoytiske preparater som inneholder dem og deres anvendelse i terapi.
US12/115,171 US20080214579A1 (en) 2003-01-17 2008-05-05 Thienopyrimidinediones and their use in the modulation of autoimmune disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0300119A SE0300119D0 (sv) 2003-01-17 2003-01-17 Novel compounds

Publications (1)

Publication Number Publication Date
SE0300119D0 true SE0300119D0 (sv) 2003-01-17

Family

ID=20290154

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0300119A SE0300119D0 (sv) 2003-01-17 2003-01-17 Novel compounds

Country Status (23)

Country Link
US (2) US7384951B2 (https=)
EP (1) EP1587812B1 (https=)
JP (1) JP4519121B2 (https=)
KR (2) KR101107486B1 (https=)
CN (1) CN100334093C (https=)
AT (1) ATE335748T1 (https=)
AU (1) AU2004206012B2 (https=)
BR (1) BRPI0406801B8 (https=)
CA (1) CA2512441C (https=)
DE (1) DE602004001857T2 (https=)
EG (1) EG25613A (https=)
ES (1) ES2270337T3 (https=)
IL (1) IL169370A (https=)
IS (1) IS2376B (https=)
MX (1) MXPA05007496A (https=)
NO (1) NO333702B1 (https=)
NZ (1) NZ541217A (https=)
PL (1) PL214682B1 (https=)
RU (1) RU2331647C2 (https=)
SE (1) SE0300119D0 (https=)
UA (1) UA81788C2 (https=)
WO (1) WO2004065394A1 (https=)
ZA (1) ZA200505364B (https=)

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* Cited by examiner, † Cited by third party
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GB0117583D0 (en) * 2001-07-19 2001-09-12 Astrazeneca Ab Novel compounds
GB0118479D0 (en) * 2001-07-28 2001-09-19 Astrazeneca Ab Novel compounds
SE0300120D0 (sv) * 2003-01-17 2003-01-17 Astrazeneca Ab Novel compounds
MXPA05007495A (es) * 2003-01-17 2005-09-21 Astrazeneca Ab Tienopiridazinonas y su uso en la modulacion de enfermedades autoinmunes.
CN1925855B (zh) 2003-12-19 2010-06-16 普莱希科公司 开发Ret调节剂的化合物和方法
US7498342B2 (en) 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
US7846941B2 (en) 2005-05-17 2010-12-07 Plexxikon, Inc. Compounds modulating c-kit and c-fms activity and uses therefor
UA95244C2 (ru) 2005-06-22 2011-07-25 Плексикон, Инк. Соединения и способ модулирования активности киназ, и показания для их применения
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
JP2010514695A (ja) 2006-12-21 2010-05-06 プレキシコン，インコーポレーテッド キナーゼ調節のための化合物および方法およびそのための適応症
WO2008079909A1 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
PE20121126A1 (es) 2006-12-21 2012-08-24 Plexxikon Inc Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
GB0713479D0 (en) * 2007-07-11 2007-08-22 Syngenta Participations Ag Substituted aromatic heterocyclic compounds as fungicides
WO2009012283A1 (en) 2007-07-17 2009-01-22 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
WO2010089580A1 (en) 2009-02-06 2010-08-12 Astrazeneca Ab Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4
EP2411395B1 (en) * 2009-03-23 2013-05-29 Glenmark Pharmaceuticals S.A. Furopyrimidinedione derivatives as trpa1 modulators
WO2010109328A1 (en) * 2009-03-23 2010-09-30 Glenmark Pharmaceuticals, S.A. Isothiazolo-pyrimidinedione derivatives as trpa1 modulators
MY172424A (en) 2009-04-03 2019-11-25 Hoffmann La Roche Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
CN106220623A (zh) 2009-11-06 2016-12-14 普莱希科公司 用于激酶调节的化合物和方法及其适应症
US9624213B2 (en) 2011-02-07 2017-04-18 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
WO2013109972A2 (en) 2012-01-20 2013-07-25 Regents Of The University Of Minnesota Therapeutic compounds
WO2013112881A1 (en) 2012-01-27 2013-08-01 Thomas Jefferson University Mct protein inhibitor-related prognostic and therapeutic methods
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
US10022372B2 (en) 2013-04-19 2018-07-17 Thomas Jefferson University Caveolin-1 related methods for treating glioblastoma with temozolomide
PL3060562T3 (pl) * 2013-10-21 2022-01-10 Genosco Podstawione związki pirymidynowe i ich zastosowanie jako inhibitory syk
CA2974697A1 (en) 2015-01-22 2016-07-28 The Scripps Research Institute Pyrimidine-2,4-(1h,3h)-dione derivatives and pharmaceutical compositions thereof and their use as inhibitors of monocarboxylate transporters
UY36586A (es) * 2015-03-26 2016-10-31 Bayer Pharma AG Heterociclilmetiltienouracilos y uso de los mismos
KR101730536B1 (ko) * 2016-03-17 2017-05-02 주식회사 골프존 스크린 골프 시스템에서 구현되는 컨텐츠 전송 서비스 방법, 컨텐츠 전송 서비스를 위한 모바일 단말기의 제어방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록매체
KR101712838B1 (ko) * 2016-03-17 2017-03-07 주식회사 골프존 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101712836B1 (ko) * 2016-03-17 2017-03-22 주식회사 골프존 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
TWI823932B (zh) * 2018-05-11 2023-12-01 中國大陸商迪哲（江蘇）醫藥有限公司 三唑并嘧啶化合物及其在治療癌症中之用途
CN119080799B (zh) * 2024-09-27 2025-12-05 山东大学 一种n-羟基噻吩并嘧啶二酮类衍生物及其制备方法与应用

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US738495A (en) * 1902-12-26 1903-09-08 William E Sherwood Thill-coupling.
WO1999029695A1 (en) 1997-12-05 1999-06-17 Astrazeneca Uk Limited Novel compounds
US6469014B1 (en) * 1997-05-28 2002-10-22 Astrazeneca Ab Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy
SE9702001D0 (sv) 1997-05-28 1997-05-28 Astra Pharma Prod Novel compounds
US6232320B1 (en) 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
DE69912618T2 (de) 1998-08-28 2004-10-28 Astrazeneca Ab NEUE THIENO[2,3-d]PYRIMIDINDIONE, VERFAHREN FÜR IHRE HERSTELLUNG UND IHRE VERWENDUNG IN DER THERAPIE
EP1280806B1 (en) * 2000-05-04 2004-08-04 AstraZeneca AB THIENO 2,3-d]PYRIMIDINEDIONES AND THEIR USE AS PHARMACEUTICALS
GB0117583D0 (en) * 2001-07-19 2001-09-12 Astrazeneca Ab Novel compounds
GB0118479D0 (en) 2001-07-28 2001-09-19 Astrazeneca Ab Novel compounds
MXPA05007495A (es) 2003-01-17 2005-09-21 Astrazeneca Ab Tienopiridazinonas y su uso en la modulacion de enfermedades autoinmunes.
SE0300120D0 (sv) * 2003-01-17 2003-01-17 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
WO2004065394A1 (en) 2004-08-05
CN1761672A (zh) 2006-04-19
NZ541217A (en) 2008-05-30
RU2005121494A (ru) 2006-02-10
ZA200505364B (en) 2006-09-27
MXPA05007496A (es) 2005-09-21
CA2512441C (en) 2012-01-03
DE602004001857T2 (de) 2007-05-24
IL169370A (en) 2011-05-31
JP4519121B2 (ja) 2010-08-04
RU2331647C2 (ru) 2008-08-20
KR101107486B1 (ko) 2012-01-19
CN100334093C (zh) 2007-08-29
NO20053826L (no) 2005-10-17
EP1587812A1 (en) 2005-10-26
AU2004206012B2 (en) 2007-06-14
PL378222A1 (pl) 2006-03-20
IS7965A (is) 2005-07-29
NO333702B1 (no) 2013-08-26
IL169370A0 (en) 2007-07-04
UA81788C2 (uk) 2008-02-11
ATE335748T1 (de) 2006-09-15
IS2376B (is) 2008-07-15
EP1587812B1 (en) 2006-08-09
EG25613A (en) 2012-03-22
ES2270337T3 (es) 2007-04-01
JP2006516974A (ja) 2006-07-13
DE602004001857D1 (de) 2006-09-21
US7384951B2 (en) 2008-06-10
BRPI0406801A (pt) 2006-01-17
PL214682B1 (pl) 2013-09-30
KR20110125256A (ko) 2011-11-18
NO20053826D0 (no) 2005-08-15
HK1081959A1 (en) 2006-05-26
US20060052400A1 (en) 2006-03-09
AU2004206012A1 (en) 2004-08-05
BRPI0406801B8 (pt) 2021-05-25
KR20050092760A (ko) 2005-09-22
US20080214579A1 (en) 2008-09-04
BRPI0406801B1 (pt) 2018-04-03
CA2512441A1 (en) 2004-08-05

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