SE0103818D0 - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
SE0103818D0
SE0103818D0 SE0103818A SE0103818A SE0103818D0 SE 0103818 D0 SE0103818 D0 SE 0103818D0 SE 0103818 A SE0103818 A SE 0103818A SE 0103818 A SE0103818 A SE 0103818A SE 0103818 D0 SE0103818 D0 SE 0103818D0
Authority
SE
Sweden
Prior art keywords
chemical compounds
compounds
compositions
preparing
processes
Prior art date
Application number
SE0103818A
Other languages
English (en)
Swedish (sv)
Inventor
Howard Tucker
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0103818A priority Critical patent/SE0103818D0/xx
Publication of SE0103818D0 publication Critical patent/SE0103818D0/xx
Priority to TW091132376A priority patent/TW200407139A/zh
Priority to MXPA04004503A priority patent/MXPA04004503A/es
Priority to BR0214140-0A priority patent/BR0214140A/pt
Priority to CNB028225406A priority patent/CN100398535C/zh
Priority to CA002464347A priority patent/CA2464347A1/en
Priority to NZ532411A priority patent/NZ532411A/en
Priority to PL02369758A priority patent/PL369758A1/xx
Priority to IL16169902A priority patent/IL161699A0/xx
Priority to JP2003544041A priority patent/JP4459622B2/ja
Priority to EP02789054A priority patent/EP1448548A1/en
Priority to AU2002353691A priority patent/AU2002353691B2/en
Priority to US10/495,196 priority patent/US7192973B2/en
Priority to RU2004111601/04A priority patent/RU2345990C2/ru
Priority to PCT/SE2002/002055 priority patent/WO2003042205A1/en
Priority to HU0402261A priority patent/HUP0402261A3/hu
Priority to ARP020104333A priority patent/AR037351A1/es
Priority to KR1020047007364A priority patent/KR20050044470A/ko
Priority to MYPI20024233A priority patent/MY137144A/en
Priority to UA20040402736A priority patent/UA77969C2/uk
Priority to IL161699A priority patent/IL161699A/en
Priority to IS7256A priority patent/IS7256A/is
Priority to ZA200403688A priority patent/ZA200403688B/en
Priority to NO20042157A priority patent/NO327221B1/no
Priority to US11/687,257 priority patent/US20070161646A1/en
Priority to IL196059A priority patent/IL196059A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96Sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
SE0103818A 2001-11-15 2001-11-15 Chemical compounds SE0103818D0 (sv)

Priority Applications (26)

Application Number Priority Date Filing Date Title
SE0103818A SE0103818D0 (sv) 2001-11-15 2001-11-15 Chemical compounds
TW091132376A TW200407139A (en) 2001-11-15 2002-11-01 Chemical compounds
KR1020047007364A KR20050044470A (ko) 2001-11-15 2002-11-12 피페리딘 유도체 및 그의 케모킨 수용체 활성의조절제로서의 용도 (특히 ccr5)
US10/495,196 US7192973B2 (en) 2001-11-15 2002-11-12 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially CCR5)
RU2004111601/04A RU2345990C2 (ru) 2001-11-15 2002-11-12 Производные пиперидина в качестве модуляторов активности рецептора ccr5, способы и промежуточные соединения для их получения и фармацевтические композиции, содержащие их
CNB028225406A CN100398535C (zh) 2001-11-15 2002-11-12 哌啶衍生物及其作为趋化因子受体(尤其是ccr5)活性调节剂的用途
CA002464347A CA2464347A1 (en) 2001-11-15 2002-11-12 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
NZ532411A NZ532411A (en) 2001-11-15 2002-11-12 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially CCR5)
PL02369758A PL369758A1 (en) 2001-11-15 2002-11-12 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
IL16169902A IL161699A0 (en) 2001-11-15 2002-11-12 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
JP2003544041A JP4459622B2 (ja) 2001-11-15 2002-11-12 ピペリジン誘導体およびケモカイン・レセプター(特にccr5)活性モジュレーターとしてのその使用
EP02789054A EP1448548A1 (en) 2001-11-15 2002-11-12 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
AU2002353691A AU2002353691B2 (en) 2001-11-15 2002-11-12 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially CCR5)
MXPA04004503A MXPA04004503A (es) 2001-11-15 2002-11-12 Derivados de piperina y su uso como moduladores de actividad receptora de quimiocina (especialmente ccr5).
BR0214140-0A BR0214140A (pt) 2001-11-15 2002-11-12 Derivados de piperidina e sua utilização como moduladores da atividade de receptor de quimiocina (especialmente ccr5)
PCT/SE2002/002055 WO2003042205A1 (en) 2001-11-15 2002-11-12 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
HU0402261A HUP0402261A3 (en) 2001-11-15 2002-11-12 Piperidine derivatives and their use as modulators of chemokine receptor activity, process for their preparation and pharmaceutical compositions containing them
ARP020104333A AR037351A1 (es) 2001-11-15 2002-11-12 Derivados de piperidina, proceso para preparar estos compuestos, composicion farmaceutica, uso de estos compuestos para la manufactura de un medicamento util para el tratamiento de una enfermedad mediada por ccr5 (tal como artritis reumatoidea) y compuestos intermediarios
MYPI20024233A MY137144A (en) 2001-11-15 2002-11-13 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
UA20040402736A UA77969C2 (en) 2001-11-15 2002-12-11 Piperidine derivatives and their use for modulating ccr5 receptor activity, process for their manufacture, pharmaceutical composition and intermediate compound
IL161699A IL161699A (en) 2001-11-15 2004-04-29 Piperidine derivatives, process for their preparation, pharmaceutical compositions comprising them and uses thereof in the manufacture of medicaments
IS7256A IS7256A (is) 2001-11-15 2004-05-10 Píperidínafleiður og notkun þeirra sem stilla á virkni flakkboðaviðtaka (einkum CCR5)
ZA200403688A ZA200403688B (en) 2001-11-15 2004-05-13 Piperidine derivatives and their use as modulators of chemokine receptor activity (especialy CCR5).
NO20042157A NO327221B1 (no) 2001-11-15 2004-05-25 Piperidinderivater, fremgangsmate for deres fremstilling, farmasoytisk preparat, anvendelser og mellomprodukter
US11/687,257 US20070161646A1 (en) 2001-11-15 2007-03-16 Piperidine Derivatives and Their Use as Modulators of Chemokine Receptor Activity (Especially CCR5)
IL196059A IL196059A (en) 2001-11-15 2008-12-18 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0103818A SE0103818D0 (sv) 2001-11-15 2001-11-15 Chemical compounds

Publications (1)

Publication Number Publication Date
SE0103818D0 true SE0103818D0 (sv) 2001-11-15

Family

ID=20286005

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0103818A SE0103818D0 (sv) 2001-11-15 2001-11-15 Chemical compounds

Country Status (23)

Country Link
US (2) US7192973B2 (xx)
EP (1) EP1448548A1 (xx)
JP (1) JP4459622B2 (xx)
KR (1) KR20050044470A (xx)
CN (1) CN100398535C (xx)
AR (1) AR037351A1 (xx)
AU (1) AU2002353691B2 (xx)
BR (1) BR0214140A (xx)
CA (1) CA2464347A1 (xx)
HU (1) HUP0402261A3 (xx)
IL (3) IL161699A0 (xx)
IS (1) IS7256A (xx)
MX (1) MXPA04004503A (xx)
MY (1) MY137144A (xx)
NO (1) NO327221B1 (xx)
NZ (1) NZ532411A (xx)
PL (1) PL369758A1 (xx)
RU (1) RU2345990C2 (xx)
SE (1) SE0103818D0 (xx)
TW (1) TW200407139A (xx)
UA (1) UA77969C2 (xx)
WO (1) WO2003042205A1 (xx)
ZA (1) ZA200403688B (xx)

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SE9902987D0 (sv) * 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
GB2395059B (en) * 2002-11-05 2005-03-16 Imp College Innovations Ltd Structured silicon anode
US20040192738A1 (en) * 2003-03-18 2004-09-30 Aventis Pharma Deutschland Gmbh 2-(Butyl-1-sulfonylamino)-N-[1(R)-(6-methoxypyridin-3-yl)propyl] benzamide, its use as a medicament, and pharmaceutical preparations comprising it
SE0301369D0 (sv) * 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds
SE0302090D0 (sv) * 2003-07-16 2003-07-16 Astrazeneca Ab Chemical compounds
ES2285485T3 (es) * 2003-07-31 2007-11-16 Astrazeneca Ab Derivados de piperidina como moduladores del receptor ccr5.
US7550485B2 (en) * 2003-10-14 2009-06-23 Wyeth Substituted N-heterocycle derivatives and methods of their use
SE0303396D0 (sv) * 2003-12-16 2003-12-16 Astrazeneca Ab Chemical compounds
MXPA06011722A (es) * 2004-04-13 2007-01-25 Incyte Corp Derivados de piperazinilpiperidina como antagonistas del receptor de quimiocina.
TW200610761A (en) * 2004-04-23 2006-04-01 Astrazeneca Ab Chemical compounds
CN1329374C (zh) * 2004-06-09 2007-08-01 上海靶点药物有限公司 作为ccr5拮抗剂的化合物
SE0401656D0 (sv) * 2004-06-24 2004-06-24 Astrazeneca Ab Chemical compounds
SE0401657D0 (sv) * 2004-06-24 2004-06-24 Astrazeneca Ab Chemical compounds
SE0403084D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Chemical process
US20080108586A1 (en) * 2006-09-06 2008-05-08 Incyte Corporation Combination therapy for human immunodeficiency virus infection
WO2009010478A2 (en) * 2007-07-13 2009-01-22 Euroscreen S.A. Use of piperidine derivatives as agonists of chemokine receptor activity
WO2012113103A1 (en) 2011-02-25 2012-08-30 Helsinn Healthcare S.A. Asymmetric ureas and medical uses thereof
US10351535B2 (en) * 2013-12-20 2019-07-16 Esteve Pharmaceuticals, S.A. Piperazine derivatives having multimodal activity against pain
TWI690512B (zh) * 2014-03-07 2020-04-11 瑞士商赫爾辛保健股份有限公司 對位取代的不對稱脲及其醫療用途
FI3390355T3 (fi) 2016-03-22 2023-04-04 Helsinn Healthcare Sa Asymmetrisiä bentseenisulfonyyliureoita ja niiden lääketieteellisiä käyttöjä

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US20070161646A1 (en) 2007-07-12
ZA200403688B (en) 2005-08-10
JP2005510522A (ja) 2005-04-21
UA77969C2 (en) 2007-02-15
EP1448548A1 (en) 2004-08-25
IL161699A (en) 2012-12-31
PL369758A1 (en) 2005-05-02
TW200407139A (en) 2004-05-16
HUP0402261A2 (hu) 2005-02-28
KR20050044470A (ko) 2005-05-12
US20040267016A1 (en) 2004-12-30
MY137144A (en) 2008-12-31
US7192973B2 (en) 2007-03-20
JP4459622B2 (ja) 2010-04-28
CN100398535C (zh) 2008-07-02
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MXPA04004503A (es) 2004-08-11
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RU2345990C2 (ru) 2009-02-10
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WO2003042205A1 (en) 2003-05-22
IS7256A (is) 2004-05-10
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