SE0101038D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0101038D0
SE0101038D0 SE0101038A SE0101038A SE0101038D0 SE 0101038 D0 SE0101038 D0 SE 0101038D0 SE 0101038 A SE0101038 A SE 0101038A SE 0101038 A SE0101038 A SE 0101038A SE 0101038 D0 SE0101038 D0 SE 0101038D0
Authority
SE
Sweden
Prior art keywords
sup
novel compounds
therapy
general formula
pharmaceutical compositions
Prior art date
Application number
SE0101038A
Other languages
English (en)
Swedish (sv)
Inventor
Tomas Eriksson
Karolina Lawitz
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0101038A priority Critical patent/SE0101038D0/xx
Publication of SE0101038D0 publication Critical patent/SE0101038D0/xx
Priority to SI200230517T priority patent/SI1372651T1/sl
Priority to CA002441933A priority patent/CA2441933A1/en
Priority to CNA028070968A priority patent/CN1538844A/zh
Priority to DE60218641T priority patent/DE60218641T2/de
Priority to US10/472,017 priority patent/US7345063B2/en
Priority to JP2002574972A priority patent/JP2004524345A/ja
Priority to DK02708893T priority patent/DK1372651T3/da
Priority to ES02708893T priority patent/ES2280511T3/es
Priority to IL15765302A priority patent/IL157653A0/xx
Priority to NZ528296A priority patent/NZ528296A/en
Priority to BR0208336-1A priority patent/BR0208336A/pt
Priority to KR10-2003-7012302A priority patent/KR20030085030A/ko
Priority to MXPA03008443A priority patent/MXPA03008443A/es
Priority to PT02708893T priority patent/PT1372651E/pt
Priority to AT02708893T priority patent/ATE355842T1/de
Priority to PCT/SE2002/000541 priority patent/WO2002076457A1/en
Priority to EP02708893A priority patent/EP1372651B1/en
Priority to ZA200306792A priority patent/ZA200306792B/en
Priority to NO20034215A priority patent/NO20034215L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
SE0101038A 2001-03-23 2001-03-23 Novel compounds SE0101038D0 (sv)

Priority Applications (20)

Application Number Priority Date Filing Date Title
SE0101038A SE0101038D0 (sv) 2001-03-23 2001-03-23 Novel compounds
EP02708893A EP1372651B1 (en) 2001-03-23 2002-03-19 Novel amides, preparation and therapeutic use as modulators of ccr-receptor activity
ES02708893T ES2280511T3 (es) 2001-03-23 2002-03-19 Nuevas amidas, preparacion y uso terapeutico como moduladores de la actividad del receptor de ccr.
NZ528296A NZ528296A (en) 2001-03-23 2002-03-19 Novel amides, preparation and therapeutic use as modulators of CCR-receptor activity
CNA028070968A CN1538844A (zh) 2001-03-23 2002-03-19 用作ccr受体活性调节剂的新型酰胺类化合物、其制备及治疗用途
DE60218641T DE60218641T2 (de) 2001-03-23 2002-03-19 Neue amide, herstellung und therapeutische verwendung als modulatoren der ccr-rezeptor-aktivität
US10/472,017 US7345063B2 (en) 2001-03-23 2002-03-19 Amides, preparation and therapeutic use as modulators of CCR-receptor activity
JP2002574972A JP2004524345A (ja) 2001-03-23 2002-03-19 Ｃｃｒ受容体活性のモジュレーターとしての新規アミド、製法、および治療的使用
DK02708893T DK1372651T3 (da) 2001-03-23 2002-03-19 Hidtil ukendte amider, fremstilling og terapeutisk anvendelse som modulatorer af CCR-receptoraktivitet
SI200230517T SI1372651T1 (sl) 2001-03-23 2002-03-19 Novi amidi, priprava in terapevtska uporaba kot modulatorji aktivnosti CCR-receptorjev
IL15765302A IL157653A0 (en) 2001-03-23 2002-03-19 Novel amides, preparation and therapeutic use as modulators of ccr-receptor activity
CA002441933A CA2441933A1 (en) 2001-03-23 2002-03-19 Novel amides, preparation and therapeutic use as modulators of ccr-receptor activity
BR0208336-1A BR0208336A (pt) 2001-03-23 2002-03-19 Novas amidas, preparação e uso terapêutico como moduladores de atividade de receptor-ccr
KR10-2003-7012302A KR20030085030A (ko) 2001-03-23 2002-03-19 신규 아미드, 이의 제법 및 ｃｃｒ-수용체 활성조절자로서의 치료 용도
MXPA03008443A MXPA03008443A (es) 2001-03-23 2002-03-19 Amidas nuevas, preparacion y uso terapeutico como moduladores de actividad del receptor ccr.
PT02708893T PT1372651E (pt) 2001-03-23 2002-03-19 Novas amidas, preparação e utilização terapia como moduladores da actividade do receptor ccr
AT02708893T ATE355842T1 (de) 2001-03-23 2002-03-19 Neue amide, herstellung und therapeutische verwendung als modulatoren der ccr-rezeptor- aktivität
PCT/SE2002/000541 WO2002076457A1 (en) 2001-03-23 2002-03-19 Novel amides, preparation and therapeutic use as modulators of ccr-receptor activity
ZA200306792A ZA200306792B (en) 2001-03-23 2003-08-29 Novel amides, preparation and therapeutic use as modulators of CCR-receptor activity.
NO20034215A NO20034215L (no) 2001-03-23 2003-09-22 Nye amider, fremstilling og terapeutisk anvendelse av modulatorer av CCR-reseptoraktivitet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0101038A SE0101038D0 (sv) 2001-03-23 2001-03-23 Novel compounds

Publications (1)

Publication Number Publication Date
SE0101038D0 true SE0101038D0 (sv) 2001-03-23

Family

ID=20283509

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0101038A SE0101038D0 (sv) 2001-03-23 2001-03-23 Novel compounds

Country Status (20)

Country Link
US (1) US7345063B2 (xx)
EP (1) EP1372651B1 (xx)
JP (1) JP2004524345A (xx)
KR (1) KR20030085030A (xx)
CN (1) CN1538844A (xx)
AT (1) ATE355842T1 (xx)
BR (1) BR0208336A (xx)
CA (1) CA2441933A1 (xx)
DE (1) DE60218641T2 (xx)
DK (1) DK1372651T3 (xx)
ES (1) ES2280511T3 (xx)
IL (1) IL157653A0 (xx)
MX (1) MXPA03008443A (xx)
NO (1) NO20034215L (xx)
NZ (1) NZ528296A (xx)
PT (1) PT1372651E (xx)
SE (1) SE0101038D0 (xx)
SI (1) SI1372651T1 (xx)
WO (1) WO2002076457A1 (xx)
ZA (1) ZA200306792B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
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CO5300399A1 (es) 2000-02-25 2003-07-31 Astrazeneca Ab Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen
US7005439B2 (en) * 2000-06-20 2006-02-28 Astrazeneca Ab Compounds
AR028948A1 (es) * 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
EP1661889A4 (en) * 2003-09-05 2009-08-05 Ono Pharmaceutical Co ANTAGONIST OF THE CHEMOKINE RECEPTOR AND ITS USE FOR MEDICAL PURPOSES
PT1899322E (pt) 2005-06-28 2009-11-09 Sanofi Aventis Derivados de isoquinolina como inibidores de rho-cinase
RS52241B (en) 2005-07-26 2012-10-31 Sanofi CYCLOHEXYLAMINE ISOHINOLONE DERIVATIVES AS RHO-KINASE INHIBITORS
BRPI0613861B8 (pt) 2005-07-26 2021-05-25 Sanofi Aventis derivados de isoquinolona piperidinil-substituídos como inibidores de rho-cinase
TW200738634A (en) * 2005-08-02 2007-10-16 Astrazeneca Ab New salt
ATE490243T1 (de) 2006-12-27 2010-12-15 Sanofi Aventis Cycloalkylaminsubstituierte isochinolin- und isochinolinonderivate
MX2009006517A (es) 2006-12-27 2009-06-26 Sanofi Aventis Nuevos derivados de isoquinolina e isoquinolinona sustituidos.
JP5405316B2 (ja) 2006-12-27 2014-02-05 サノフイ シクロアルキルアミン置換イソキノリン誘導体
WO2008077555A2 (en) 2006-12-27 2008-07-03 Sanofi-Aventis Substituted isoquinolines and their use as rho-kinase inhibitors
ES2625266T3 (es) 2006-12-27 2017-07-19 Sanofi Derivados de isoquinolona sustituidos con cicloalquilamina
CN101616909B (zh) 2006-12-27 2013-09-11 塞诺菲-安万特股份有限公司 作为Rho-激酶抑制剂的被取代的异喹啉和异喹啉酮衍生物
MX2010013974A (es) 2008-06-24 2011-01-14 Sanofi Aventis Isoquinolinas e isoquinolinonas 6-sustituidas.
CN102131784B (zh) 2008-06-24 2014-08-27 赛诺菲-安万特 作为rho激酶抑制剂的取代的异喹啉和异喹啉酮
JP5715561B2 (ja) 2008-06-24 2015-05-07 サノフイ 二及び多環式置換イソキノリン及びイソキノリノン誘導体

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JP4782342B2 (ja) * 1999-12-17 2011-09-28 サノフィ−アベンティス フェノキシプロパノールアミン類、それらの製造方法およびそれらを含む医薬組成物
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CO5300399A1 (es) * 2000-02-25 2003-07-31 Astrazeneca Ab Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen
GB0011838D0 (en) 2000-05-17 2000-07-05 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
ATE355842T1 (de) 2007-03-15
WO2002076457A1 (en) 2002-10-03
ZA200306792B (en) 2004-11-29
KR20030085030A (ko) 2003-11-01
BR0208336A (pt) 2004-03-23
IL157653A0 (en) 2004-03-28
US7345063B2 (en) 2008-03-18
PT1372651E (pt) 2007-05-31
DE60218641T2 (de) 2007-11-29
MXPA03008443A (es) 2004-01-29
CA2441933A1 (en) 2002-10-03
NO20034215D0 (no) 2003-09-22
ES2280511T3 (es) 2007-09-16
US20040122020A1 (en) 2004-06-24
DE60218641D1 (de) 2007-04-19
JP2004524345A (ja) 2004-08-12
CN1538844A (zh) 2004-10-20
EP1372651A1 (en) 2004-01-02
NO20034215L (no) 2003-11-24
NZ528296A (en) 2005-03-24
SI1372651T1 (sl) 2007-06-30
DK1372651T3 (da) 2007-05-29
EP1372651B1 (en) 2007-03-07

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