SA516371583B1 - مركبات بينزو بيران وظيفية واستخدامها - Google Patents

مركبات بينزو بيران وظيفية واستخدامها Download PDF

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Publication number
SA516371583B1
SA516371583B1 SA516371583A SA516371583A SA516371583B1 SA 516371583 B1 SA516371583 B1 SA 516371583B1 SA 516371583 A SA516371583 A SA 516371583A SA 516371583 A SA516371583 A SA 516371583A SA 516371583 B1 SA516371583 B1 SA 516371583B1
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SA
Saudi Arabia
Prior art keywords
cancer
compound
formula
compounds
group
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SA516371583A
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Arabic (ar)
English (en)
Inventor
هيتون اندريو
كيلى جراهام
برون ديفيد
Original Assignee
نوفوجين ليمتد
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Application filed by نوفوجين ليمتد filed Critical نوفوجين ليمتد
Publication of SA516371583B1 publication Critical patent/SA516371583B1/ar

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/10Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing aromatic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SA516371583A 2014-02-07 2016-07-31 مركبات بينزو بيران وظيفية واستخدامها SA516371583B1 (ar)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461937368P 2014-02-07 2014-02-07
US201461987323P 2014-05-01 2014-05-01
PCT/AU2015/050040 WO2015117202A1 (en) 2014-02-07 2015-02-05 Functionalised benzopyran compounds and use thereof

Publications (1)

Publication Number Publication Date
SA516371583B1 true SA516371583B1 (ar) 2019-04-18

Family

ID=53777071

Family Applications (1)

Application Number Title Priority Date Filing Date
SA516371583A SA516371583B1 (ar) 2014-02-07 2016-07-31 مركبات بينزو بيران وظيفية واستخدامها

Country Status (24)

Country Link
US (2) US9701655B2 (enExample)
EP (1) EP2953938B1 (enExample)
JP (1) JP6570042B2 (enExample)
KR (1) KR102395543B1 (enExample)
CN (2) CN108484559A (enExample)
AU (1) AU2015213484B2 (enExample)
BR (1) BR112016018099B8 (enExample)
CA (1) CA2936012C (enExample)
CL (1) CL2016001937A1 (enExample)
DK (1) DK2953938T3 (enExample)
ES (1) ES2643407T3 (enExample)
IL (1) IL241515B (enExample)
LT (1) LT2953938T (enExample)
MX (1) MX368063B (enExample)
MY (1) MY195739A (enExample)
NZ (1) NZ711603A (enExample)
PH (1) PH12016501422B1 (enExample)
PL (1) PL2953938T3 (enExample)
PT (1) PT2953938T (enExample)
RU (1) RU2676766C2 (enExample)
SA (1) SA516371583B1 (enExample)
SG (2) SG11201506988TA (enExample)
SI (1) SI2953938T1 (enExample)
WO (1) WO2015117202A1 (enExample)

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PL2953938T3 (pl) * 2014-02-07 2017-12-29 Novogen Ltd. Funkcjonalizowane związki benzopiranowe i ich zastosowanie
CN107427003B (zh) 2015-02-02 2023-01-31 梅制药公司 联合治疗
US10265294B2 (en) * 2016-03-31 2019-04-23 Yale University Compositions and methods for treating epithelial cancer
EP3439642A4 (en) * 2016-04-06 2019-11-13 Noxopharm Limited IMPROVEMENTS IN RADIOTHERAPY
AU2017247008B2 (en) 2016-04-06 2022-04-07 Noxopharm Limited Isoflavonoid composition with improved pharmacokinetics
CN109730996B (zh) * 2017-03-01 2021-08-24 浙江大学 喹啉结构类型雄激素受体拮抗剂及其应用
EP4125870A1 (en) 2020-03-30 2023-02-08 Noxopharm Limited Methods for the treatment of inflammation associated with infection
CA3181730A1 (en) * 2020-06-11 2021-12-16 Daniel P. Gold Combination therapies
WO2023235929A1 (en) * 2022-06-08 2023-12-14 Noxopharm Limited Functionalised benzopyran compounds and uses thereof
CN118005594B (zh) * 2023-05-24 2024-10-29 内蒙古大学 3-羟基苯并二氢吡喃衍生物的合成及其抗肿瘤活性

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Also Published As

Publication number Publication date
SG11201604490SA (en) 2016-07-28
JP2017507175A (ja) 2017-03-16
PH12016501422B1 (en) 2022-02-16
KR20160110427A (ko) 2016-09-21
MX2016010137A (es) 2017-02-15
PH12016501422A1 (en) 2016-08-31
IL241515A0 (en) 2015-11-30
CN105980372B (zh) 2018-05-08
RU2016133731A (ru) 2018-03-12
CA2936012A1 (en) 2015-08-13
BR112016018099A2 (pt) 2017-08-08
EP2953938B1 (en) 2017-08-02
HK1218914A1 (en) 2017-03-17
MY195739A (en) 2023-02-08
AU2015213484A1 (en) 2015-09-17
CA2936012C (en) 2023-03-07
US9701655B2 (en) 2017-07-11
PL2953938T3 (pl) 2017-12-29
EP2953938A4 (en) 2016-08-10
PT2953938T (pt) 2017-10-09
US10370349B2 (en) 2019-08-06
RU2016133731A3 (enExample) 2018-08-08
LT2953938T (lt) 2017-10-10
AU2015213484B2 (en) 2015-11-05
CN105980372A (zh) 2016-09-28
SG11201506988TA (en) 2015-10-29
CL2016001937A1 (es) 2017-01-20
ES2643407T3 (es) 2017-11-22
DK2953938T3 (en) 2017-10-02
SI2953938T1 (en) 2018-01-31
NZ711603A (en) 2017-05-26
US20160340329A1 (en) 2016-11-24
KR102395543B1 (ko) 2022-05-09
JP6570042B2 (ja) 2019-09-04
BR112016018099B8 (pt) 2023-01-17
WO2015117202A1 (en) 2015-08-13
RU2676766C2 (ru) 2019-01-11
IL241515B (en) 2019-06-30
EP2953938A1 (en) 2015-12-16
MX368063B (es) 2019-09-18
US20180141925A1 (en) 2018-05-24
CN108484559A (zh) 2018-09-04
BR112016018099B1 (pt) 2022-10-11

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