SA516370640B1 - وسيلة وطرق لاستخدام الوسيلة للكشف عن فرط أمونيا الدم - Google Patents

وسيلة وطرق لاستخدام الوسيلة للكشف عن فرط أمونيا الدم Download PDF

Info

Publication number
SA516370640B1
SA516370640B1 SA516370640A SA516370640A SA516370640B1 SA 516370640 B1 SA516370640 B1 SA 516370640B1 SA 516370640 A SA516370640 A SA 516370640A SA 516370640 A SA516370640 A SA 516370640A SA 516370640 B1 SA516370640 B1 SA 516370640B1
Authority
SA
Saudi Arabia
Prior art keywords
biosensor
rrr
sample
see
ammonia
Prior art date
Application number
SA516370640A
Other languages
Arabic (ar)
English (en)
Inventor
مايكل بيرينس آدم
سيمونوف انطوان
كوفيناس بيتر
جونينجام جاري
ماروجان جوان
مانويل كابريرا-لوكيو جوان
بلال ايوب عمر
لاين سومار مارشيل
Original Assignee
تشيلدرينز ناشونال ميديكل سينتر
ذا يونايتد ستيتس اوف امريكا، از ريبرسنتد باي ذا سيكرتاري، ديبارتمنت اوف هيلث آند هيومان سيرفيسز، اوفيس اوف تيكولوجي ترانسفير، ناشونال انستيتيوت اوف هيلث
يونفيرسيتي اوف ماريلاند، كوليج بارك
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by تشيلدرينز ناشونال ميديكل سينتر, ذا يونايتد ستيتس اوف امريكا، از ريبرسنتد باي ذا سيكرتاري، ديبارتمنت اوف هيلث آند هيومان سيرفيسز، اوفيس اوف تيكولوجي ترانسفير، ناشونال انستيتيوت اوف هيلث, يونفيرسيتي اوف ماريلاند، كوليج بارك filed Critical تشيلدرينز ناشونال ميديكل سينتر
Publication of SA516370640B1 publication Critical patent/SA516370640B1/ar

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4925Blood measuring blood gas content, e.g. O2, CO2, HCO3
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plasma & Fusion (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
SA516370640A 2013-08-30 2016-02-28 وسيلة وطرق لاستخدام الوسيلة للكشف عن فرط أمونيا الدم SA516370640B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361872149P 2013-08-30 2013-08-30
PCT/US2014/053756 WO2015031911A1 (en) 2013-08-30 2014-09-02 Device and methods of using device for detection of hyperammonemia

Publications (1)

Publication Number Publication Date
SA516370640B1 true SA516370640B1 (ar) 2019-02-24

Family

ID=52587421

Family Applications (1)

Application Number Title Priority Date Filing Date
SA516370640A SA516370640B1 (ar) 2013-08-30 2016-02-28 وسيلة وطرق لاستخدام الوسيلة للكشف عن فرط أمونيا الدم

Country Status (15)

Country Link
US (2) US9952199B2 (enExample)
EP (2) EP3039422B1 (enExample)
JP (1) JP6646579B2 (enExample)
KR (1) KR102278346B1 (enExample)
CN (1) CN105940300B (enExample)
AU (1) AU2014311977B2 (enExample)
BR (1) BR112016004320B1 (enExample)
CA (1) CA2922821C (enExample)
CL (1) CL2016000467A1 (enExample)
DK (2) DK3540429T3 (enExample)
IL (1) IL244274B (enExample)
MX (1) MX2016002632A (enExample)
SA (1) SA516370640B1 (enExample)
TR (1) TR201903528T4 (enExample)
WO (1) WO2015031911A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160092653A1 (en) * 2014-09-30 2016-03-31 Koninklijke Philips N.V. NUTRITIONAL INTAKE VIEWER (NutriWeb)
WO2016176366A1 (en) * 2015-04-27 2016-11-03 University Of Maryland, College Park Device and methods of using device for detection of hyperammonemia
US10792339B2 (en) 2015-07-17 2020-10-06 Children's National Medical Center Methods and compositions for treating phenylketonuria
CA3026706C (en) 2016-08-16 2024-01-09 Eth Zurich Transmembrane ph-gradient polymersomes and their use in the scavenging of ammonia and its methylated analogs
KR101920272B1 (ko) * 2016-11-22 2018-11-20 (주)인트인 조명이 개선된 체액 검사장치
PL3668927T3 (pl) * 2017-09-12 2024-06-24 Eth Zurich Przezbłonowe polimerosomy z gradientem pH do ilościowego oznaczania amoniaku w płynach ustrojowych
KR20250103785A (ko) * 2018-01-12 2025-07-07 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 체액 중의 암모니아 및 암모늄의 검출 및 정량화를 위한 시스템 및 방법
WO2020186362A1 (en) * 2019-03-20 2020-09-24 Mcmaster University Differential signal biosensing for detecting an analyte
US11156991B2 (en) 2019-06-24 2021-10-26 Nanotronics Imaging, Inc. Predictive process control for a manufacturing process
US20220364076A1 (en) * 2019-07-02 2022-11-17 The Texas A&M University System Microfluidic platform for selective exosome isolation
WO2021055792A1 (en) * 2019-09-20 2021-03-25 The Board Of Trustees Of The Leland Stanford Junior University Electrochemical pre-concentration for improved detection of gaseous species in water
AU2020370511A1 (en) * 2019-10-23 2022-06-09 President And Fellows Of Harvard College Sensing devices based on microneedle arrays for sensing applications including ketone bodies monitoring
CN110806448B (zh) * 2019-11-21 2022-03-22 北京市药品检验所 测定复方氨基酸注射液中游离氨的方法
KR102369697B1 (ko) * 2020-05-18 2022-03-03 국민대학교산학협력단 바이오 센싱 모듈, 바이오 센싱 장치, 및 이를 포함하는 바이오 센싱 시스템
WO2022008714A1 (en) * 2020-07-10 2022-01-13 Radiometer Medical Aps A blood gas analyzer and a system comprising a blood gas analyzer, and use thereof
EP3968009B1 (en) * 2020-09-10 2024-11-06 Hach Lange GmbH Method for determining ammonium
US20250000957A1 (en) * 2021-09-16 2025-01-02 Arcturus Therapeutics, Inc. Compositions and methods for treating phenylketonuria
EP4449118A4 (en) 2021-12-14 2025-04-02 Gazi Universitesi Rektorlugu Biosensor system for quantitative measurement of phenylalanine from blood
CN114088026B (zh) * 2022-01-20 2022-04-05 江苏奥琳斯邦装备科技股份有限公司 一种应变测量的热压固化装置以及固化方法
US12030045B1 (en) 2023-01-05 2024-07-09 Sequitur Health Corp. Devices, methods, and systems for deriving ammonia gas from whole blood
US12140534B2 (en) 2023-01-05 2024-11-12 Sequitur Health Corp. Devices, methods, and systems for deriving a permeate from a feed solution
GB2633752A (en) * 2023-09-14 2025-03-26 Palintest Ltd Electrochemical detection of monochloramine and/or ammonia

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5786053A (en) * 1980-11-18 1982-05-28 Yokogawa Hokushin Electric Corp Method and device for measuring amino compound
JPS59187249A (ja) * 1983-04-07 1984-10-24 Fuji Electric Corp Res & Dev Ltd 尿素窒素分析装置
JPS63218860A (ja) * 1987-03-07 1988-09-12 Aoki Hiroko 溶液中のアンモニアの定量方法
US5128015A (en) 1988-03-15 1992-07-07 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
JP2739484B2 (ja) * 1988-09-29 1998-04-15 株式会社ヤトロン 自動分析装置用尿素窒素測定試薬
JPH02104272A (ja) * 1988-10-12 1990-04-17 Ricoh Co Ltd 液体検出装置
US5243516A (en) 1989-12-15 1993-09-07 Boehringer Mannheim Corporation Biosensing instrument and method
US4999582A (en) 1989-12-15 1991-03-12 Boehringer Mannheim Corp. Biosensor electrode excitation circuit
US4963814A (en) 1989-12-15 1990-10-16 Boehringer Mannheim Corporation Regulated bifurcated power supply
US4999632A (en) 1989-12-15 1991-03-12 Boehringer Mannheim Corporation Analog to digital conversion with noise reduction
DE4318519C2 (de) 1993-06-03 1996-11-28 Fraunhofer Ges Forschung Elektrochemischer Sensor
JP2704046B2 (ja) 1993-06-08 1998-01-26 ベーリンガー マンハイム コーポレーション 適切な電極の接続を検出し、サンプル片及びチェック片を区別するバイオセンシングメータ
US5366609A (en) 1993-06-08 1994-11-22 Boehringer Mannheim Corporation Biosensing meter with pluggable memory key
US5405511A (en) 1993-06-08 1995-04-11 Boehringer Mannheim Corporation Biosensing meter with ambient temperature estimation method and system
US5352351A (en) 1993-06-08 1994-10-04 Boehringer Mannheim Corporation Biosensing meter with fail/safe procedures to prevent erroneous indications
US5762770A (en) 1994-02-21 1998-06-09 Boehringer Mannheim Corporation Electrochemical biosensor test strip
AU2365895A (en) * 1994-04-26 1995-11-16 Regents Of The University Of Michigan, The Unitary sandwich enzyme immunoassay cassette, device and method of use
US5624537A (en) 1994-09-20 1997-04-29 The University Of British Columbia - University-Industry Liaison Office Biosensor and interface membrane
US5698083A (en) 1995-08-18 1997-12-16 Regents Of The University Of California Chemiresistor urea sensor
JPH09271398A (ja) * 1996-02-09 1997-10-21 Asahi Chem Ind Co Ltd アンモニア測定法および測定用組成物
JP2000146899A (ja) 1998-11-06 2000-05-26 Horiba Ltd アンモニウムイオン測定装置
ES2224614T3 (es) 1999-03-19 2005-03-01 Sapporo Immuno Diagnostic Laboratory Procedimiento de analisis de substrato y biosensor.
US6645359B1 (en) 2000-10-06 2003-11-11 Roche Diagnostics Corporation Biosensor
US6662439B1 (en) 1999-10-04 2003-12-16 Roche Diagnostics Corporation Laser defined features for patterned laminates and electrodes
CA2453141A1 (en) * 2001-07-09 2003-01-23 Arizona Board Of Regents A Body Corporate Acting On Behalf Of Arizona State University Afinity biosensor for monitoring of biological process
US7150975B2 (en) * 2002-08-19 2006-12-19 Animas Technologies, Llc Hydrogel composition for measuring glucose flux
US9101302B2 (en) 2004-05-03 2015-08-11 Abbott Diabetes Care Inc. Analyte test device
JP2006126092A (ja) * 2004-10-29 2006-05-18 Ntt Advanced Technology Corp 薄層流路および透析膜を有する微小バイオセンサ
US8409864B2 (en) * 2006-01-06 2013-04-02 Renal Solutions, Inc. Ammonia sensor and system for use
US20090294302A1 (en) * 2008-05-28 2009-12-03 John Pasqua Use of Alginate to Reduce Hematocrit Bias in Biosensors
JP2010160134A (ja) * 2008-12-11 2010-07-22 Unitika Ltd 検知材および定量方法
JP2014010145A (ja) 2012-07-02 2014-01-20 Aquatech Co Ltd 液中アンモニアを検知し、反応を制御する装置

Also Published As

Publication number Publication date
CL2016000467A1 (es) 2016-10-28
US20180284099A1 (en) 2018-10-04
EP3039422B1 (en) 2019-01-09
JP6646579B2 (ja) 2020-02-14
DK3540429T3 (da) 2021-02-15
US9952199B2 (en) 2018-04-24
EP3540429A1 (en) 2019-09-18
IL244274A0 (en) 2016-04-21
IL244274B (en) 2020-09-30
CN105940300B (zh) 2019-01-22
KR20160048204A (ko) 2016-05-03
EP3540429B1 (en) 2020-11-11
US10620187B2 (en) 2020-04-14
BR112016004320A2 (pt) 2017-10-24
JP2016529515A (ja) 2016-09-23
EP3039422A4 (en) 2017-04-19
BR112016004320B1 (pt) 2022-03-03
TR201903528T4 (tr) 2019-04-22
AU2014311977B2 (en) 2019-02-21
KR102278346B1 (ko) 2021-07-19
AU2014311977A1 (en) 2016-03-17
CN105940300A (zh) 2016-09-14
CA2922821C (en) 2023-01-03
CA2922821A1 (en) 2015-03-05
WO2015031911A1 (en) 2015-03-05
US20160231310A1 (en) 2016-08-11
MX2016002632A (es) 2016-10-04
DK3039422T3 (en) 2019-03-25
EP3039422A1 (en) 2016-07-06

Similar Documents

Publication Publication Date Title
SA516370640B1 (ar) وسيلة وطرق لاستخدام الوسيلة للكشف عن فرط أمونيا الدم
JP2016529515A5 (enExample)
CN103805170B (zh) 一种用于识别硫化氢的特异性荧光探针及其应用
JP5829766B2 (ja) 酵素法を利用したヘモグロビンA1c定量分析のための溶血試薬組成物
ElKaoutit et al. A comparison of three amperometric phenoloxidase–Sonogel–Carbon based biosensors for determination of polyphenols in beers
EP3517966B1 (en) Reagent composition for measuring glycated hemoglobin and method for measuring glycated hemoglobin using same
Li et al. Glucose biosensor based on the room-temperature phosphorescence of TiO2/SiO2 nanocomposite
CN108276990A (zh) 一种区分GSH、Cys、NAC荧光探针及其制备方法和应用
JP4520999B2 (ja) ポリマー電解質、電気化学的測定用の半電池、およびこれらの使用
CN103472055B (zh) 基于纳米金形成的可视化检测过氧化氢酶的方法
Pavão e Pavão et al. A Simple, Cost‐effective, and Environmentally Friendly Method for Determination of Ciprofloxacin in Drugs and Urine Samples Based on Electrogenerated Chemiluminescence
CN107084938B (zh) 基于壳聚糖-铂模拟氧化酶的碱性磷酸酶测定方法
Cavalieri et al. Studies on the Structure of Nucleic Acids. VI. The Kinetics of Desoxyribonuclease Action1
CN109971463B (zh) 一种检测细胞内溶酶体no的比率型荧光探针及其应用
CN106967721A (zh) Atp核酸适配体、利用纳米金显色检测atp的方法及试剂盒
KR102802646B1 (ko) 시료 내 바이오마커를 이용하는 질병 자가 진단 장치
López et al. A sensitive glucose biosensor based on brushite, a biocompatible cement
Zhou et al. Advanced electrochemical strategy for in vivo detection of electrochemically inactive molecules
CN111088320A (zh) α-L-岩藻糖苷酶测定试剂
Vymazalová et al. Photocolorimetric biosensor for detection of cholinergic organophosphorus compounds
US11268953B2 (en) Reagent composition for measuring glycated hemoglobin and method for measuring glycated hemoglobin using same
KR20240062120A (ko) 바이오마커 검출체, 그의 제조방법, 및 바이오마커 검출방법
EP0753742B1 (en) Stable liquid urobilinogen control composition
Baker Glucose Oxidase and Prussian Blue Nanoparticles Encapsulated within a Xerogel for Electrochemical Detection of Glucose
KR101496411B1 (ko) 산소 측정용 미세전극의 보정 방법