CL2016000467A1 - Biosensor para medir amoniaco yo amonio en una muestra, kit que comprende el biosensor y métodos de uso - Google Patents

Biosensor para medir amoniaco yo amonio en una muestra, kit que comprende el biosensor y métodos de uso

Info

Publication number
CL2016000467A1
CL2016000467A1 CL2016000467A CL2016000467A CL2016000467A1 CL 2016000467 A1 CL2016000467 A1 CL 2016000467A1 CL 2016000467 A CL2016000467 A CL 2016000467A CL 2016000467 A CL2016000467 A CL 2016000467A CL 2016000467 A1 CL2016000467 A1 CL 2016000467A1
Authority
CL
Chile
Prior art keywords
biosensor
ammonia
container
kit
sample
Prior art date
Application number
CL2016000467A
Other languages
English (en)
Spanish (es)
Inventor
Omar Bilal Ayyub
Adam Michael Behrens
Peter Kofinas
Marchal Lynn Summar
Juan Manuel Cabrera-Luque
Gary Cunningham
Anton Simeonov
Juan MARUGAN
Original Assignee
Univ Maryland
Childrens Nat Medical Ct
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maryland, Childrens Nat Medical Ct, Us Health filed Critical Univ Maryland
Publication of CL2016000467A1 publication Critical patent/CL2016000467A1/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4925Blood measuring blood gas content, e.g. O2, CO2, HCO3
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plasma & Fusion (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
CL2016000467A 2013-08-30 2016-02-29 Biosensor para medir amoniaco yo amonio en una muestra, kit que comprende el biosensor y métodos de uso CL2016000467A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361872149P 2013-08-30 2013-08-30

Publications (1)

Publication Number Publication Date
CL2016000467A1 true CL2016000467A1 (es) 2016-10-28

Family

ID=52587421

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016000467A CL2016000467A1 (es) 2013-08-30 2016-02-29 Biosensor para medir amoniaco yo amonio en una muestra, kit que comprende el biosensor y métodos de uso

Country Status (15)

Country Link
US (2) US9952199B2 (enExample)
EP (2) EP3039422B1 (enExample)
JP (1) JP6646579B2 (enExample)
KR (1) KR102278346B1 (enExample)
CN (1) CN105940300B (enExample)
AU (1) AU2014311977B2 (enExample)
BR (1) BR112016004320B1 (enExample)
CA (1) CA2922821C (enExample)
CL (1) CL2016000467A1 (enExample)
DK (2) DK3039422T3 (enExample)
IL (1) IL244274B (enExample)
MX (1) MX2016002632A (enExample)
SA (1) SA516370640B1 (enExample)
TR (1) TR201903528T4 (enExample)
WO (1) WO2015031911A1 (enExample)

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US20160092653A1 (en) * 2014-09-30 2016-03-31 Koninklijke Philips N.V. NUTRITIONAL INTAKE VIEWER (NutriWeb)
EP3289353B1 (en) * 2015-04-27 2024-09-25 University of Maryland, College Park Device and methods of using device for detection of hyperammonemia
US10792339B2 (en) 2015-07-17 2020-10-06 Children's National Medical Center Methods and compositions for treating phenylketonuria
CN109803685B (zh) 2016-08-16 2023-02-17 瑞士苏黎世联邦理工学院 跨膜pH-梯度聚合物囊泡及其制备方法
KR101920272B1 (ko) * 2016-11-22 2018-11-20 (주)인트인 조명이 개선된 체액 검사장치
CN110945076B (zh) * 2017-09-12 2023-10-17 苏黎士联邦理工大学 用于定量体液中的氨的跨膜pH梯度聚合物囊泡
US11793431B2 (en) 2018-01-12 2023-10-24 Mayo Foundation For Medical Education And Research Systems and methods for the detection and quantification of ammonia and ammonium in fluids
EP3942285B1 (en) * 2019-03-20 2025-05-14 McMaster University Differential signal biosensing for detecting an analyte
US11156991B2 (en) 2019-06-24 2021-10-26 Nanotronics Imaging, Inc. Predictive process control for a manufacturing process
US20220364076A1 (en) * 2019-07-02 2022-11-17 The Texas A&M University System Microfluidic platform for selective exosome isolation
US12596114B2 (en) 2019-09-20 2026-04-07 The Board Of Trustees Of The Leland Stanford Junior University Electrochemical pre-concentration for improved detection of gaseous species in water
US20220361776A1 (en) * 2019-10-23 2022-11-17 The Regents Of The University Of California Sensing devices based on microneedle arrays for sensing applications including ketone bodies monitoring
CN110806448B (zh) * 2019-11-21 2022-03-22 北京市药品检验所 测定复方氨基酸注射液中游离氨的方法
KR102369697B1 (ko) * 2020-05-18 2022-03-03 국민대학교산학협력단 바이오 센싱 모듈, 바이오 센싱 장치, 및 이를 포함하는 바이오 센싱 시스템
JP7558379B2 (ja) * 2020-07-10 2024-09-30 ラジオメーター・メディカル・アー・ペー・エス 血液ガス分析装置、および血液ガス分析装置を備えるシステム、ならびにその使用
EP3968009B1 (en) * 2020-09-10 2024-11-06 Hach Lange GmbH Method for determining ammonium
US20250000957A1 (en) * 2021-09-16 2025-01-02 Arcturus Therapeutics, Inc. Compositions and methods for treating phenylketonuria
EP4449118A4 (en) 2021-12-14 2025-04-02 Gazi Universitesi Rektorlugu Biosensor system for quantitative measurement of phenylalanine from blood
CN114088026B (zh) * 2022-01-20 2022-04-05 江苏奥琳斯邦装备科技股份有限公司 一种应变测量的热压固化装置以及固化方法
US12030045B1 (en) 2023-01-05 2024-07-09 Sequitur Health Corp. Devices, methods, and systems for deriving ammonia gas from whole blood
US12140534B2 (en) 2023-01-05 2024-11-12 Sequitur Health Corp. Devices, methods, and systems for deriving a permeate from a feed solution
GB2633752B (en) * 2023-09-14 2026-03-11 Palintest Ltd Electrochemical detection of monochloramine and/or ammonia
CN121359911B (zh) * 2025-12-17 2026-02-17 华东师范大学 无创体液采样的同型半胱氨酸检测系统

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Also Published As

Publication number Publication date
EP3540429B1 (en) 2020-11-11
US9952199B2 (en) 2018-04-24
CN105940300A (zh) 2016-09-14
IL244274A0 (en) 2016-04-21
US20180284099A1 (en) 2018-10-04
JP2016529515A (ja) 2016-09-23
AU2014311977A1 (en) 2016-03-17
EP3540429A1 (en) 2019-09-18
DK3039422T3 (en) 2019-03-25
US20160231310A1 (en) 2016-08-11
EP3039422A1 (en) 2016-07-06
BR112016004320B1 (pt) 2022-03-03
CA2922821C (en) 2023-01-03
WO2015031911A1 (en) 2015-03-05
CA2922821A1 (en) 2015-03-05
JP6646579B2 (ja) 2020-02-14
BR112016004320A2 (pt) 2017-10-24
AU2014311977B2 (en) 2019-02-21
TR201903528T4 (tr) 2019-04-22
EP3039422A4 (en) 2017-04-19
KR102278346B1 (ko) 2021-07-19
DK3540429T3 (da) 2021-02-15
KR20160048204A (ko) 2016-05-03
CN105940300B (zh) 2019-01-22
US10620187B2 (en) 2020-04-14
IL244274B (en) 2020-09-30
MX2016002632A (es) 2016-10-04
EP3039422B1 (en) 2019-01-09
SA516370640B1 (ar) 2019-02-24

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